2-Minute Neuroscience: Schizophrenia
  • View Times: 0
  • |
  • Release Date: 2023-11-21
Neuroscience Made Simpler
2-Minute Neuroscience: Zolpidem (Ambien)
2-Minute Neuroscience: Zolpidem (Ambien)
10-Minute Neuroscience: Depression
10-Minute Neuroscience: Depression
2-Minute Neuroscience: Sleepwalking
2-Minute Neuroscience: Sleepwalking
2-Minute Neuroscience: Vertigo
2-Minute Neuroscience: Vertigo
2-Minute Neuroscience: Migraine
2-Minute Neuroscience: Migraine
2-Minute Neuroscience: Methylphenidate
2-Minute Neuroscience: Methylphenidate
2-Minute Neuroscience: DMT
2-Minute Neuroscience: DMT
2-Minute Neuroscience: Cochlear Implants
2-Minute Neuroscience: Cochlear Implants
2-Minute Neuroscience: Frontotemporal Dementia
2-Minute Neuroscience: Frontotemporal Dementia
2-Minute Neuroscience: Spina Bifida
2-Minute Neuroscience: Spina Bifida
2-Minute Neuroscience: Sleep Paralysis
2-Minute Neuroscience: Sleep Paralysis
2-Minute Neuroscience: Fatal Insomnia
2-Minute Neuroscience: Fatal Insomnia
2-Minute Neuroscience: PTSD
2-Minute Neuroscience: PTSD
2-Minute Neuroscience: Schizophrenia
2-Minute Neuroscience: Schizophrenia
2-Minute Neuroscience: COVID-19 & the Brain
2-Minute Neuroscience: COVID-19 & the Brain
2-Minute Neuroscience: Obsessive-Compulsive Disorder
2-Minute Neuroscience: Obsessive-Compulsive Disorder
2-Minute Neuroscience: ADHD
2-Minute Neuroscience: ADHD
2-Minute Neuroscience: Restless Legs Syndrome
2-Minute Neuroscience: Restless Legs Syndrome
2-Minute Neuroscience: Autism
2-Minute Neuroscience: Autism
2-Minute Neuroscience: Narcolepsy
2-Minute Neuroscience: Narcolepsy
2-Minute Neuroscience: MDMA
2-Minute Neuroscience: MDMA
2-Minute Neuroscience: Brain Aneurysms
2-Minute Neuroscience: Brain Aneurysms
2-Minute Neuroscience: Bell's Palsy
2-Minute Neuroscience: Bell's Palsy
2-Minute Neuroscience: Tinnitus
2-Minute Neuroscience: Tinnitus
2-Minute Neuroscience: Ketamine
2-Minute Neuroscience: Ketamine
2-Minute Neuroscience: Chronic Traumatic Encephalopathy
2-Minute Neuroscience: Chronic Traumatic Encephalopathy
2-Minute Neuroscience: Motor Neurons
2-Minute Neuroscience: Motor Neurons
2-Minute Neuroscience: Phantom Limb
2-Minute Neuroscience: Phantom Limb
10-Minute Neuroscience: Visual Pathways
10-Minute Neuroscience: Visual Pathways
10-Minute Neuroscience: Action Potentials
10-Minute Neuroscience: Action Potentials
10-Minute Neuroscience: Synapses
10-Minute Neuroscience: Synapses
10-Minute Neuroscience: Neurons
10-Minute Neuroscience: Neurons
2-Minute Neuroscience: Tourette Syndrome
2-Minute Neuroscience: Tourette Syndrome
2-Minute Neuroscience: Withdrawal Reflex
2-Minute Neuroscience: Withdrawal Reflex
2-Minute Neuroscience: Serotonin-Norepinephrine Reuptake Inhibitors
2-Minute Neuroscience: Serotonin-Norepinephrine Reuptake Inhibitors
2-Minute Neuroscience: Cerebral Cortex
2-Minute Neuroscience: Cerebral Cortex
2-Minute Neuroscience: Deep Brain Stimulation
2-Minute Neuroscience: Deep Brain Stimulation
2-Minute Neuroscience: Meningitis
2-Minute Neuroscience: Meningitis
2-Minute Neuroscience: Wernicke-Korsakoff Syndrome
2-Minute Neuroscience: Wernicke-Korsakoff Syndrome
2-Minute Neuroscience: Corneal Reflex
2-Minute Neuroscience: Corneal Reflex
2-Minute Neuroscience: CBD
2-Minute Neuroscience: CBD
2-Minute Neuroscience: THC
2-Minute Neuroscience: THC
2-Minute Neuroscience: Alien Hand Syndrome
2-Minute Neuroscience: Alien Hand Syndrome
2-Minute Neuroscience: Melatonin
2-Minute Neuroscience: Melatonin
2-Minute Neuroscience: Psilocybin
2-Minute Neuroscience: Psilocybin
2-Minute Neuroscience: Agonism, Antagonism, & Allosteric Modulation
2-Minute Neuroscience: Agonism, Antagonism, & Allosteric Modulation
2-Minute Neuroscience: LSD
2-Minute Neuroscience: LSD
2-Minute Neuroscience: Beta-Endorphin
2-Minute Neuroscience: Beta-Endorphin
2-Minute Neuroscience: L-DOPA
2-Minute Neuroscience: L-DOPA
2-Minute Neuroscience: Parasympathetic Nervous System
2-Minute Neuroscience: Parasympathetic Nervous System
2-Minute Neuroscience: Sympathetic Nervous System
2-Minute Neuroscience: Sympathetic Nervous System
2-Minute Neuroscience: Indirect Pathway of the Basal Ganglia
2-Minute Neuroscience: Indirect Pathway of the Basal Ganglia
2-Minute Neuroscience: Direct Pathway of the Basal Ganglia
2-Minute Neuroscience: Direct Pathway of the Basal Ganglia
2-Minute Neuroscience: Functional Magnetic Resonance Imaging (fMRI)
2-Minute Neuroscience: Functional Magnetic Resonance Imaging (fMRI)
2-Minute Neuroscience: Norepinephrine
2-Minute Neuroscience: Norepinephrine
2-Minute Neuroscience: Sodium-Potassium Pump
2-Minute Neuroscience: Sodium-Potassium Pump
2-Minute Neuroscience: Electroencephalography (EEG)
2-Minute Neuroscience: Electroencephalography (EEG)
2-Minute Neuroscience: Trochlear Nerve (Cranial Nerve IV)
2-Minute Neuroscience: Trochlear Nerve (Cranial Nerve IV)
2-Minute Neuroscience: Oculomotor Nerve (Cranial Nerve III)
2-Minute Neuroscience: Oculomotor Nerve (Cranial Nerve III)
2-Minute Neuroscience: Touch Receptors
2-Minute Neuroscience: Touch Receptors
2-Minute Neuroscience: Hypoglossal Nerve (Cranial Nerve XII)
2-Minute Neuroscience: Hypoglossal Nerve (Cranial Nerve XII)
2-Minute Neuroscience: Accessory Nerve (Cranial Nerve XI)
2-Minute Neuroscience: Accessory Nerve (Cranial Nerve XI)
2-Minute Neuroscience: Prefrontal Cortex
2-Minute Neuroscience: Prefrontal Cortex
2-Minute Neuroscience: Vagus Nerve (Cranial Nerve X)
2-Minute Neuroscience: Vagus Nerve (Cranial Nerve X)
2-Minute Neuroscience: Phototransduction
2-Minute Neuroscience: Phototransduction
2-Minute Neuroscience: Glossopharyngeal Nerve (Cranial Nerve IX)
2-Minute Neuroscience: Glossopharyngeal Nerve (Cranial Nerve IX)
2-Minute Neuroscience: Methadone
2-Minute Neuroscience: Methadone
2-Minute Neuroscience: Vestibulocochlear Nerve (Cranial Nerve VIII)
2-Minute Neuroscience: Vestibulocochlear Nerve (Cranial Nerve VIII)
2-Minute Neuroscience: Nicotine
2-Minute Neuroscience: Nicotine
2-Minute Neuroscience: Facial Nerve (Cranial Nerve VII)
2-Minute Neuroscience: Facial Nerve (Cranial Nerve VII)
2-Minute Neuroscience: Abducens Nerve (Cranial Nerve VI)
2-Minute Neuroscience: Abducens Nerve (Cranial Nerve VI)
2-Minute Neuroscience: Concussions
2-Minute Neuroscience: Concussions
2-Minute Neuroscience: Trigeminal Nerve (Cranial Nerve V)
2-Minute Neuroscience: Trigeminal Nerve (Cranial Nerve V)
2-Minute Neuroscience: Opioids
2-Minute Neuroscience: Opioids
2-Minute Neuroscience: Optic Nerve (Cranial Nerve II)
2-Minute Neuroscience: Optic Nerve (Cranial Nerve II)
2-Minute Neuroscience: Olfactory Nerve (Cranial Nerve I)
2-Minute Neuroscience: Olfactory Nerve (Cranial Nerve I)
2-Minute Neuroscience: Brain Tumors
2-Minute Neuroscience: Brain Tumors
2-Minute Neuroscience: Glial Cells
2-Minute Neuroscience: Glial Cells
2-Minute Neuroscience: Stages of Sleep
2-Minute Neuroscience: Stages of Sleep
2-Minute Neuroscience: HPA Axis
2-Minute Neuroscience: HPA Axis
2-Minute Neuroscience: Huntington's Disease
2-Minute Neuroscience: Huntington's Disease
2-Minute Neuroscience: Amphetamine
2-Minute Neuroscience: Amphetamine
2-Minute Neuroscience: Corpus Callosum
2-Minute Neuroscience: Corpus Callosum
2-Minute Neuroscience: Pons
2-Minute Neuroscience: Pons
2-Minute Neuroscience: Parkinson's Disease
2-Minute Neuroscience: Parkinson's Disease
2-Minute Neuroscience: Hydrocephalus
2-Minute Neuroscience: Hydrocephalus
2-Minute Neuroscience: Dopamine
2-Minute Neuroscience: Dopamine
2-Minute Neuroscience: Stroke
2-Minute Neuroscience: Stroke
2-Minute Neuroscience: Glutamate
2-Minute Neuroscience: Glutamate
2-Minute Neuroscience: Blood Supply of the Brain
2-Minute Neuroscience: Blood Supply of the Brain
2-Minute Neuroscience: Neurotransmitter Release
2-Minute Neuroscience: Neurotransmitter Release
2-Minute Neuroscience: Serotonin
2-Minute Neuroscience: Serotonin
2-Minute Neuroscience: Oxytocin
2-Minute Neuroscience: Oxytocin
2-Minute Neuroscience: Long-Term Potentiation (LTP)
2-Minute Neuroscience: Long-Term Potentiation (LTP)
2-Minute Neuroscience: Wernicke's Area
2-Minute Neuroscience: Wernicke's Area
2-Minute Neuroscience: Broca's Area
2-Minute Neuroscience: Broca's Area
2-Minute Neuroscience: Acetylcholine
2-Minute Neuroscience: Acetylcholine
2-Minute Neuroscience: GABA
2-Minute Neuroscience: GABA
2-Minute Neuroscience: Taste
2-Minute Neuroscience: Taste
2-Minute Neuroscience: Alcohol
2-Minute Neuroscience: Alcohol
2-Minute Neuroscience: Olfaction
2-Minute Neuroscience: Olfaction
2-Minute Neuroscience: Selective Serotonin Reuptake Inhibitors (SSRIs)
2-Minute Neuroscience: Selective Serotonin Reuptake Inhibitors (SSRIs)
2-Minute Neuroscience: Midbrain
2-Minute Neuroscience: Midbrain
2-Minute Neuroscience: Periaqueductal Gray (PAG)
2-Minute Neuroscience: Periaqueductal Gray (PAG)
2-Minute Neuroscience: Benzodiazepines
2-Minute Neuroscience: Benzodiazepines
2-Minute Neuroscience: Caffeine
2-Minute Neuroscience: Caffeine
2-Minute Neuroscience: Long-Term Depression (LTD)
2-Minute Neuroscience: Long-Term Depression (LTD)
2-Minute Neuroscience: Amyotrophic Lateral Sclerosis (ALS)
2-Minute Neuroscience: Amyotrophic Lateral Sclerosis (ALS)
2-Minute Neuroscience: Pineal Gland
2-Minute Neuroscience: Pineal Gland
2-Minute Neuroscience: Primary Somatosensory Cortex
2-Minute Neuroscience: Primary Somatosensory Cortex
2-Minute Neuroscience: Suprachiasmatic Nucleus
2-Minute Neuroscience: Suprachiasmatic Nucleus
2-Minute Neuroscience: Nucleus Accumbens
2-Minute Neuroscience: Nucleus Accumbens
2-Minute Neuroscience: Ventral Tegmental Area (VTA)
2-Minute Neuroscience: Ventral Tegmental Area (VTA)
2-Minute Neuroscience: Medulla Oblongata
2-Minute Neuroscience: Medulla Oblongata
2-Minute Neuroscience: Vestibular System
2-Minute Neuroscience: Vestibular System
2-Minute Neuroscience: Amygdala
2-Minute Neuroscience: Amygdala
2-Minute Neuroscience: Striatum
2-Minute Neuroscience: Striatum
2-Minute Neuroscience: Epilepsy
2-Minute Neuroscience: Epilepsy
2-Minute Neuroscience: Multiple Sclerosis
2-Minute Neuroscience: Multiple Sclerosis
2-Minute Neuroscience: Alzheimer's Disease
2-Minute Neuroscience: Alzheimer's Disease
2-Minute Neuroscience: Neuromuscular Junction
2-Minute Neuroscience: Neuromuscular Junction
2-Minute Neuroscience: Knee-Jerk Reflex
2-Minute Neuroscience: Knee-Jerk Reflex
2-Minute Neuroscience: Substantia Nigra
2-Minute Neuroscience: Substantia Nigra
2-Minute Neuroscience: Corticospinal Tract
2-Minute Neuroscience: Corticospinal Tract
2-Minute Neuroscience: Basal Ganglia
2-Minute Neuroscience: Basal Ganglia
2-Minute Neuroscience: Motor Cortex
2-Minute Neuroscience: Motor Cortex
2-Minute Neuroscience: Cerebellum
2-Minute Neuroscience: Cerebellum
2-Minute Neuroscience: Effects of Cocaine
2-Minute Neuroscience: Effects of Cocaine
2-Minute Neuroscience: Blood-Brain Barrier
2-Minute Neuroscience: Blood-Brain Barrier
2-Minute Neuroscience: Myelin
2-Minute Neuroscience: Myelin
2-Minute Neuroscience: Pain and the Anterolateral System
2-Minute Neuroscience: Pain and the Anterolateral System
2-Minute Neuroscience: Touch and the Dorsal Columns-Medial Lemniscus
2-Minute Neuroscience: Touch and the Dorsal Columns-Medial Lemniscus
2-Minute Neuroscience: The Cochlea
2-Minute Neuroscience: The Cochlea
2-Minute Neuroscience: The Retina
2-Minute Neuroscience: The Retina
2-Minute Neuroscience: The Hippocampus
2-Minute Neuroscience: The Hippocampus
2-Minute Neuroscience: The Thalamus
2-Minute Neuroscience: The Thalamus
2-Minute Neuroscience: The Brainstem
2-Minute Neuroscience: The Brainstem
2-Minute Neuroscience: The Meninges
2-Minute Neuroscience: The Meninges
2-Minute Neuroscience: The Ventricles
2-Minute Neuroscience: The Ventricles
2-Minute Neuroscience: Directional Terms in Neuroscience
2-Minute Neuroscience: Directional Terms in Neuroscience
2-Minute Neuroscience: Spinal Cord Cross-Section
2-Minute Neuroscience: Spinal Cord Cross-Section
2-Minute Neuroscience: Exterior of the Spinal Cord
2-Minute Neuroscience: Exterior of the Spinal Cord
2-Minute Neuroscience: Reward System
2-Minute Neuroscience: Reward System
2-Minute Neuroscience: Limbic System
2-Minute Neuroscience: Limbic System
2-Minute Neuroscience: Hypothalamus & Pituitary Gland
2-Minute Neuroscience: Hypothalamus & Pituitary Gland
2-Minute Neuroscience: Neuroimaging
2-Minute Neuroscience: Neuroimaging
2-Minute Neuroscience: Early Neural Development
2-Minute Neuroscience: Early Neural Development
2-Minute Neuroscience: Receptors & Ligands
2-Minute Neuroscience: Receptors & Ligands
2-Minute Neuroscience: Lobes/Landmarks of the Brain Surface
2-Minute Neuroscience: Lobes/Landmarks of the Brain Surface
2-Minute Neuroscience: Divisions of the Nervous System
2-Minute Neuroscience: Divisions of the Nervous System
2-Minute Neuroscience: Action Potential
2-Minute Neuroscience: Action Potential
2-Minute Neuroscience: Membrane Potential
2-Minute Neuroscience: Membrane Potential
2-Minute Neuroscience: Synaptic Transmission
2-Minute Neuroscience: Synaptic Transmission
2-Minute Neuroscience: The Neuron
2-Minute Neuroscience: The Neuron
Playlist
  • schizophrenia
  • severe psychiatric condition
Video Introduction

This video is adapted from: https://www.youtube.com/watch?v=pjTmZqBNB78

Schizophrenia is a potentially severe psychiatric condition that involves a variety of symptoms. In this video, I discuss the neuroscience of schizophrenia. [1][2][3][4]

TRANSCRIPT:

Schizophrenia is a potentially severe psychiatric condition that involves a variety of symptoms. The symptoms of schizophrenia are often categorized as positive, negative, or cognitive. Positive symptoms involve the development of a behavior or thought pattern that isn’t normally present, such as hallucinations and/or delusions. Negative symptoms involve the loss of a normal function, and include lack of motivation, blunted emotion, or difficulty experiencing pleasure. Cognitive symptoms are those that affect someone’s ability to think clearly, and include deficits in attention, memory, and/or concentration.

The neuroscience of schizophrenia has been difficult to sort out, but a great deal of research has focused on neurotransmitter abnormalities at the root of the disorder. Dopamine has received much of this attention, with the general hypothesis being that dopamine activity is too high in certain parts of the brain in schizophrenia. This hypothesis was originally formulated based on the findings that drugs used to treat schizophrenia act to reduce dopamine activity, and drugs that increase dopamine levels (such as amphetamine) can induce behavior that in some ways resembles the psychotic states schizophrenic patients experience. The idea that increased dopamine activity plays a role in schizophrenic symptoms is now supported by a large body of evidence.

However, dopamine irregularities alone do not seem to explain all the symptoms of schizophrenia. Glutamate abnormalities, such as dysfunctional glutamate receptors, also occur in schizophrenia, and these may be capable of accounting for some negative and cognitive symptoms—something that dopamine levels have been less successful in explaining. Additionally, it has been proposed that dysfunction in glutamate systems may precede and lead to the dopamine hyperactivity observed in schizophrenia. While it’s uncertain what causes these neurotransmitter abnormalities to emerge in the first place, it’s generally believed that schizophrenia can be traced back to disruptions in early neural development that occur due to the influence of both genetic and environmental factors.

References
  1. Howes O, McCutcheon R, Stone J. Glutamate and dopamine in schizophrenia: an update for the 21st century. J Psychopharmacol. 2015 Feb;29(2):97-115. doi: 10.1177/0269881114563634. Epub 2015 Jan 13. PMID: 25586400; PMCID: PMC4902122.
  2. Howes OD, Murray RM. Schizophrenia: an integrated sociodevelopmental-cognitive model. Lancet. 2014 May 10;383(9929):1677-1687. doi: 10.1016/S0140-6736(13)62036-X. Epub 2013 Dec 6. PMID: 24315522; PMCID: PMC4127444.
  3. K
  4. Owen MJ, Sawa A, Mortensen PB. Schizophrenia. Lancet. 2016 Jul 2;388(10039):86-97. doi: 10.1016/S0140-6736(15)01121-6. Epub 2016 Jan 15. PMID: 26777917; PMCID: PMC4940219.
Full Transcript
1000/1000
Hot Most Recent
©Text is available under the terms and conditions of the Creative Commons-Attribution ShareAlike (CC BY-SA) license; additional terms may apply. By using this site, you agree to the Terms and Conditions and Privacy Policy.

Confirm

Are you sure to Delete?
Yes No
Cite
If you have any further questions, please contact Encyclopedia Editorial Office.
Challenged, N. 2-Minute Neuroscience: Schizophrenia. Encyclopedia. Available online: https://encyclopedia.pub/video/video_detail/977 (accessed on 21 December 2024).
Challenged N. 2-Minute Neuroscience: Schizophrenia. Encyclopedia. Available at: https://encyclopedia.pub/video/video_detail/977. Accessed December 21, 2024.
Challenged, Neuroscientifically. "2-Minute Neuroscience: Schizophrenia" Encyclopedia, https://encyclopedia.pub/video/video_detail/977 (accessed December 21, 2024).
Challenged, N. (2023, November 21). 2-Minute Neuroscience: Schizophrenia. In Encyclopedia. https://encyclopedia.pub/video/video_detail/977
Challenged, Neuroscientifically. "2-Minute Neuroscience: Schizophrenia." Encyclopedia. Web. 21 November, 2023.
Video Production Service
Feedback