In a globalized context, characterized by dominant trends towards the homogenization of food products and taste, local and niche productions play a vital role in creating effective strategies of territorial development. Albanian food heritage is definitely one of the most various of the Western Balkans. The Ottoman domination and the Mediterranean position just in front of Italy led to an incredible mix of cultures and traditions. As Albania is a candidate to join the European Union, it has a stronger opportunity of protecting its excellent-quality food products with PDO and PGI marks. Moreover, Albania’s territory shares fundamental features with Gargano lakes, especially with relation to the county of Dibër, where Ulez and Shkopet lakes are located. Both the areas’ traditional food products are and can be an important factor of sustainable and participatory development, and the present contribution aims at exploring possible paths of territorial development at a cross-border level, in the framework of a sort of “dialogue” between the two regions through Geographical Indications (GIs).
Glaucoma, a neurodegenerative disease, has a varied pathogenesis scenario, including elevated intraocular pressure (IOP), and hypoxic conditions in the retina. Consequently, degenerating optic axons at the optic nerve head are observed clinically when extensive damage has already occurred. Following elevated IOP, changes in retinal ganglion cells lead to apoptosis immediately followed by degeneration of their optic axons. Degradation of axons leads to cupping of the optic nerve head and visual field losses. Here we emphasize that it is the retinal ganglion cells that are initial targets of elevated IOP, and, together with hyperactivity of retinal astrocytes, create the ischemic conditions which represent the earliest sign in the pathogenesis of glaucoma.
Magnetic nanoparticles (MNPs) have great potential in various areas such as medicine, cancer therapy and diagnostics, biosensing, and material science. In particular, magnetite (Fe3O4) nanoparticles are extensively used for numerous bioapplications due to their biocompatibility, high saturation magnetization, chemical stability, large surface area, and easy functionalization. This paper describes magnetic nanoparticle physical and biological properties, emphasizing synthesis approaches, toxicity, and various biomedical applications, focusing on the most recent advancements in the areas of therapy, diagnostics, theranostics, magnetic separation, and biosensing.