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Topic Review
Single-Crystal Nickel-Cobalt-Manganese Cathode Research
The booming electric vehicle industry continues to place higher requirements on power batteries related to economic-cost, power density and safety. The positive electrode materials play an important role in the energy storage performance of the battery. The nickel-rich NCM (LiNixCoyMnzO2 with x + y + z = 1) materials have received increasing attention due to their high energy density, which can satisfy the demand of commercial-grade power batteries. Prominently, single-crystal nickel-rich electrodes with s unique micron-scale single-crystal structure possess excellent electrochemical and mechanical performance, even when tested at high rates, high cut-off voltages and high temperatures.
  • 4.1K
  • 27 Dec 2022
Topic Review
Newgrounds
Newgrounds (collectively Newgrounds.com, Inc.) is an American online entertainment and social media website and company. It hosts user-generated content such as gaming, filming, audio and artwork composition in four respective website categories. While AOL and Geocities had statically hosted user-generated content, Newgrounds provided visitor-driven voting and ranking of user-generated animations. The site's founder and owner, Thomas "Tom" Fulp, founded the site and company in 1995 and produces in-house content over at the headquarters and offices, based in the Glenside neighborhood of Cheltenham Township, Pennsylvania.
  • 4.1K
  • 19 Oct 2022
Topic Review
Earwax
Earwax, also known by the medical term cerumen, is a brown, orange, red, yellowish or gray waxy substance secreted in the ear canal of humans and other mammals. It protects the skin of the human ear canal, assists in cleaning and lubrication, and provides protection against bacteria, fungi, and water. Earwax consists of dead skin cells, hair, and the secretions of cerumen by the ceruminous and sebaceous glands of the outer ear canal. Major components of earwax are long chain fatty acids, both saturated and unsaturated, alcohols, squalene, and cholesterol. Excess or compacted cerumen is the buildup of ear wax causing a blockage in the ear canal and it can press against the eardrum or block the outside ear canal or hearing aids, potentially causing hearing loss.
  • 4.1K
  • 07 Nov 2022
Topic Review
Carbohydrates, Deep and REM Sleep
Carbohydrate quantity was shown to affect sleep architecture, and especially N3 and REM sleep stages. Alterations in both quantity and quality of carbohydrate intake showed a significant effect on sleep initiation. Variations in carbohydrate quality significantly affected measures of sleep continuation. Further studies are needed to assess the effect of long-term carbohydrate interventions on sleep. 
  • 4.1K
  • 28 Sep 2021
Topic Review
Three-Dimensional Printing of Living Mycelium-Based Composites
The construction industry makes a significant contribution to global CO2 emissions. Material extraction, processing, and demolition account for most of its environmental impact. As a response, there is an increasing interest in developing and implementing innovative biomaterials that support a circular economy, such as mycelium-based composites. The mycelium is the network of hyphae of fungi. Mycelium-based composites are renewable and biodegradable biomaterials obtained by ceasing mycelial growth on organic substrates, including agricultural waste.
  • 4.1K
  • 04 Sep 2023
Topic Review
Purple Tomatoes
Purple tomatoes represent a recent variant of tomato fruits characterized by a purple coloration, not present in the more common red fruited varieties. This peculiar pigmentation is due to the presence of anthocyanins. These are plant secondary metabolites responsible for red, purple and blue colorations of flowers, fruits and leaves in many species. They are usually assumed with the diet, being rich sources mostly represented by red and purple fruits or dark vegetables (e.g., berries, cherries, plums, grapes, black beans, red onions, eggplant, red cabbage, purple sweet potatoes). As other polyphenolic compounds, they can provide many health benefits, and, as a consequence, their consumption can be helpful in reducing the incidence of cardiovascular, metabolic and degenerative or chronic diseases and of certain types of cancer. Tomato fruits are naturally rich of carotenoids, vitamins and polyphenols, but do not contain anthocyanins, due to mutations in their specific biosynthetic pathway. However, in recent years, either through genetic engineering or introgression by breeding of specific gene variants using wild relatives, this biosynthetic block has been overcome. This allowed the production of the new tomatoes’ phenotypes characterized by purple pigmentation localized only on the fruit peel or in both peel and flesh. In purple tomatoes, the high concentrations of anthocyanins that can be achieved, and not to the detriment of other metabolites, represent a real added nutritional value of these fruits.
  • 4.1K
  • 15 Jan 2021
Topic Review
High Performance Liquid Chromatography with Fluorescence Detection Methods
Steroids are compounds widely available in nature and synthesized for therapeutic and medical purposes. Although several analytical techniques are available for the quantification of steroids, their analysis is challenging due to their low levels and complex matrices of the samples. The efficiency and quick separation of the high performance liquid chromatography (HPLC) combined with the sensitivity, selectivity, simplicity, and cost-efficiency of fluorescence, make HPLC coupled to fluorescence detection (HPLC-FLD) an ideal tool for routine measurement and detection of steroids.
  • 4.1K
  • 01 Aug 2022
Topic Review
Physical Activity Patterns
Although “physical activity pattern” (PAP) is a widely used expression, its precise meaning remains vague. Indeed, PAP is sometimes used to describe physical activity (PA) levels/intensities, however the term is also applied to express how PA averages differ among group,  between different days (i.e., week and weekend days), across seasons (e.g., summer, winter), and between school and vacation time. A lack of a formal definition for PAP has not prevented researchers from using a vast array of instruments to measure PA (accelerometers, pedometers, questionnaires, direct observations, and heart rate monitors) in an attempt to capture PAP. Discrepancies also exist in how PAP has been expressed with researchers using daily mean PA, heart rate frequency, number of daily steps, time engaged in certain types of activity, and/or engagement in sports activities. Researchers have also used numerous statistical procedures in their attempts to capture PAP. Notwithstanding this diversity, we suggest that PAP should be used to jointly capture similarities/dissimilarities as well as stabilities/changes in children’s PA at an intra-personal level. PAP should be used to best describe individual streams of behaviours, and not exclusively PA levels/intensities. A formal and clear definition of PAP would support important, systematic, and coherent lines of empirical enquiry.
  • 4.1K
  • 24 Apr 2021
Topic Review
Translation
In molecular biology and genetics, translation is the process in which ribosomes in the cytoplasm or endoplasmic reticulum synthesize proteins after the process of transcription of DNA to RNA in the cell's nucleus. The entire process is called gene expression. In translation, messenger RNA (mRNA) is decoded in a ribosome, outside the nucleus, to produce a specific amino acid chain, or polypeptide. The polypeptide later folds into an active protein and performs its functions in the cell. The ribosome facilitates decoding by inducing the binding of complementary tRNA anticodon sequences to mRNA codons. The tRNAs carry specific amino acids that are chained together into a polypeptide as the mRNA passes through and is "read" by the ribosome. Translation proceeds in three phases: In prokaryotes (bacteria and archaea), translation occurs in the cytosol, where the large and small subunits of the ribosome bind to the mRNA. In eukaryotes, translation occurs in the cytoplasm or across the membrane of the endoplasmic reticulum in a process called co-translational translocation. In co-translational translocation, the entire ribosome/mRNA complex binds to the outer membrane of the rough endoplasmic reticulum (ER) and the new protein is synthesized and released into the ER; the newly created polypeptide can be stored inside the ER for future vesicle transport and secretion outside the cell, or immediately secreted. Many types of transcribed RNA, such as transfer RNA, ribosomal RNA, and small nuclear RNA, do not undergo translation into proteins. A number of antibiotics act by inhibiting translation. These include anisomycin, cycloheximide, chloramphenicol, tetracycline, streptomycin, erythromycin, and puromycin. Prokaryotic ribosomes have a different structure from that of eukaryotic ribosomes, and thus antibiotics can specifically target bacterial infections without any harm to a eukaryotic host's cells.
  • 4.1K
  • 14 Nov 2022
Topic Review
Step-Down Partial Power DC-DC Converters
Photovoltaic (PV) systems made-up by two-stages of energy conversion are attractive from the operation point view. It is because the MPPT range is extended, due to the voltage decoupling between the PV system and the dc-link. Nevertheless, the additional conversion stage increases the volume, cost and power converter losses. Therefore, in large-scale PV systems formed by series connection of PV modules, most of commercial inverters are based on a single-stage system. The concept of partial power converters (PPC), previously implemented as a step-up stage, has not fully covered all PV applications. In this work, a PPC performing step-down operation is proposed and analyzed for a PV string application. This concept is actually interesting from the industry point of view, since with the new isolation standards of PV modules reaching 1500V, larger strings are currently starting to become popular. Since grid connection remains below 690V, larger strings impose more demanding operation for single-stage central inverters (required to operate at lower modulation indexes and demand higher blocking voltage devices). 
  • 4.1K
  • 01 Nov 2020
Topic Review
Mechanical Properties of BCC-Structured High-Entropy Alloys
A new metallurgical strategy was introduced to develop advanced materials with outstanding performance—high-entropy alloys (HEAs). Today, HEAs contain five or more multiple principle metallic elements in equal or near-equal atomic percentages. HEAs’ four core effects—high configurational entropy, sluggish diffusion, severe lattice distortion, and the cock-tail effect—are mainly responsible for their various physical and mechanical properties. HEAs present promising properties, such as high strength and fracture toughness at room temperature and high temperatures and have excellent wear resistance, and corrosion resistance, along with high-temperature oxidation.
  • 4.1K
  • 28 Mar 2022
Topic Review
Wearable Stretch Sensors
Wearable sensors are beneficial for continuous health monitoring, movement analysis, rehabilitation, evaluation of human performance. Wearable stretch sensors are increasingly being used for human movement monitoring. The content presented provides a review of wearable stretch sensors as well the design, development and validation of a wearable soft-robotic-stretch sensors. 
  • 4.1K
  • 25 Feb 2021
Topic Review
Polymer Solar Cells Based on PEDOT:PSS Electrodes
Solution-processed polymer solar cells (PSCs) have advantages of low cost, solution processability, light weight, and excellent flexibility. Recent progress in materials synthesis and devices engineering has boosted the power conversion efficiency (PCE) of single-junction PSCs over 17%. Poly(3,4-ethylenedioxythiophene): poly(styrenesulfonate) (PEDOT:PSS) is one of the most promising candidates for electrodes due to its high conductivity (>4000 S/cm), excellent transmittance (>90%), intrinsically high work function (WF > 5.0 eV), and aqueous solution processability. To date, a great number of single-junction PSCs based on PEDOT:PSS electrodes have realized a PCE over 12%.
  • 4.1K
  • 10 Dec 2021
Topic Review
Antibacterial Designs for Implantable Medical Devices
The uses of implantable medical devices are safer and more common since sterilization methods and techniques were established a century ago; however, device-associated infections (DAIs) are still frequent and becoming a leading complication as the number of medical device implantations keeps increasing.
  • 4.1K
  • 01 Aug 2022
Topic Review
Web Television
Web television is original episodic online video content produced for broadcast on the Internet via the World Wide Web. The phrase "web television" is also sometimes used to refer to Internet television in general, which includes Internet-transmission of programs produced for both online and traditional terrestrial, cable, or satellite broadcast. Web television content includes web series such as Carmilla, Husbands, Red vs. Blue, Teenagers, The Lizzie Bennet Diaries, and Video Game High School, among hundreds of others; original miniseries such as Dr. Horrible's Sing-Along Blog; animated shorts such as those of Homestar Runner; and exclusive video content that supplements conventional television broadcasts. The current major distributors of web television are Amazon, Crackle, Hulu, Netflix, Newgrounds, Roku, and YouTube. Examples of web television production companies include: Generate LA-NY, Next New Networks, Revision3, and Vuguru. In 2008, the International Academy of Web Television, headquartered in Los Angeles, formed in order to organize and support web television actors, authors, executives, and producers. The organization also administers the selection of winners for the Streamy Awards. In 2009, the Los Angeles Web Series Festival was founded. Several other festivals and award shows have been dedicated solely to web content, including the Indie Series Awards and the Vancouver Web Series Festival. In 2013, in response to the shifting of the soap opera All My Children from broadcast to web television, a new category for "Fantastic web-only series" in the Daytime Emmy Awards was created. Later that year, Netflix made history by earning the first Primetime Emmy Award nominations for web television series, for Arrested Development, Hemlock Grove, and House of Cards, at the 65th Primetime Emmy Awards. Hulu earned the first Emmy win for Outstanding Drama Series, for The Handmaid's Tale at the 69th Primetime Emmy Awards.
  • 4.1K
  • 01 Dec 2022
Topic Review
Senescence in Physiological Processes and Age-Related Diseases
Cellular senescence is a physiological mechanism that has both beneficial and detrimental consequences. Senescence limits tumorigenesis, lifelong tissue damage, and is involved in different biological processes, such as morphogenesis, regeneration, and wound healing. 
  • 4.1K
  • 28 Mar 2023
Topic Review
Homelessness
Homelessness is the circumstance when people are without a permanent dwelling, such as a house or apartment. People who are homeless are most often unable to acquire and maintain regular, safe, secure and adequate housing. The legal definition of homeless varies from country to country, or among different jurisdictions in the same country or region. The term homeless may also include people whose primary night-time residence is in a homeless shelter, a domestic violence shelter, long-term residence in a motel, a vehicle, squatting, cardboard boxes, a tent city, tarpaulins, shanty town structures made of discarded building materials or other ad hoc housing situations. According to the UK homelessness charity Crisis, a home is not just a physical space: it also provides roots, identity, security, a sense of belonging and a place of emotional wellbeing. United States government homeless enumeration studies also include people who sleep in a public or private place not designed for use as a regular sleeping accommodation for human beings. There are a number of organizations who provide help for the homeless. In 2005, an estimated 100 million (1 in 65 at the time) people worldwide were homeless and as many as 1 billion people live as squatters, refugees or in temporary shelter, all lacking adequate housing. In Western countries, the majority of homeless are men (50–80%), with single males particularly overrepresented. However, current data suggests similar rates of homeless males and females. Most countries provide a variety of services to assist homeless people. These services often provide food, shelter (beds) and clothing and may be organized and run by community organizations (often with the help of volunteers) or by government departments or agencies. These programs may be supported by the government, charities, churches and individual donors. Many cities also have street newspapers, which are publications designed to provide employment opportunity to homeless people. While some homeless have jobs, some must seek other methods to make a living. Begging or panhandling is one option, but is becoming increasingly illegal in many cities. People who are homeless may have additional conditions, such as physical or mental health issues or substance addiction; these issues make resolving homelessness a challenging policy issue. Homeless people, and homeless organizations, are sometimes accused or convicted of fraudulent behaviour. Criminals are also known to exploit homeless people, ranging from identity theft to tax and welfare scams. These incidents often lead to negative connotations on the homeless as a group.
  • 4.1K
  • 30 Oct 2022
Topic Review
Wire
Wire is an encrypted communication and collaboration app created by Wire Swiss. It is available for iOS, Android, Windows, macOS, Linux, and web browsers such as Firefox. Wire offers a collaboration suite featuring messenger, voice calls, video calls, conference calls, file-sharing, and external collaboration – all protected by a secure end-to-end-encryption. Wire offers three solutions built on its security technology: Wire Pro – which offers Wire's collaboration feature for businesses, Wire Enterprise – includes Wire Pro capabilities with added features for large-scale or regulated organizations, and Wire Red – the on-demand crisis collaboration suite. They also offer Wire Personal, which is a secure messaging app for personal use.
  • 4.1K
  • 04 Nov 2022
Topic Review
Ketamine and Driving, Cognitive, and Motor Ability
Ketamine is a medication that has many medical purposes but also has been used illicitly by people for its dissociative properties. While driving under the influence of drugs, drivers are more likely to be involved in and cause more accidents than drivers who do not drive under the influence.  A study with ketamine and a ketamine-like medication, rapasitnel, showed that those who were given ketamine experienced more sleepiness and had decreased self-reported motivation and confidence in their driving abilities. Moreover, there seem to be significant differences in the acute versus persistent effects of ketamine, as well as the anesthetic versus subanesthetic doses, both in terms of effects and outcomes. These divergent effects complicate the clinical uses of ketamine, specifically involving driving, drowsiness, and cognitive abilities. 
  • 4.1K
  • 16 Mar 2023
Topic Review
Early-Age Cracking in Concrete
Cracking is a common problem in concrete structures in real-life service conditions. In fact, crack-free concrete structures are very rare to find in real world. Concrete can undergo early-age cracking depending on the mix composition, exposure environment, hydration rate, and curing conditions.
  • 4.1K
  • 27 Jun 2021
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