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Topic Review
Detection of Viruses Using Electrochemical Biosensors
Electrochemical biosensors have tremendous potential for point-of-care virus detection due to their portability and simple detection methods. The main limitation of this method is its sensitivity. Numerous studies have been conducted in an attempt to enhance the key elements of electrochemical-based biosensing systems.
  • 1.7K
  • 13 Sep 2022
Topic Review
Plug-in Electric Vehicles in Australia
The adoption of plug-in electric vehicles in Australia is driven mostly by state-based electric vehicle targets and monetary incentives to support the adoption and deployment of low- or zero-emission vehicles. The monetary incentives include electric vehicle subsidies, interest-free loans, registration exemptions, stamp duty exemptions, the luxury car tax exemption and discounted parking for both private and commercial purchases. The Clean Energy Finance Corporation, energy providers, car loan providers and car insurance providers also offer their own financial incentives for electric vehicle purchases including Macquarie Bank offering the lowest electric car loan of 2.99%. The Victorian and New South Wales governments target between 50% to 53% of new car sales to be electric vehicles by 2030. The New South Wales Government also aim for the vast majority of new cars sold in the state to be electric vehicles by 2035. The New South Wales Government are also planning and stated they must ban the sale of internal combustion-engine vehicles by 2035. Similarly, the Victorian Government's "Infrastructure Victoria" initiative called for the government to ban the sale of petrol and diesel engine vehicles by 2035 at the latest. South Australia's Liberal government aim for 100% of new car sales to be electric vehicles by 2035, and plan to ensure electric vehicles are mainstream and the "common choice" for new vehicle purchases in 2030. The ACT also plan for 100% of new car sales to be EVs by 2030. The Australian states with EV sales targets represent approximately 65% of the Australian population. This means 65% of the Australian population has a target to reach more than 50% EV car sales by 2030. However, this target could be reached sooner if the two largest states governments of New South Wales and Victoria enact their plan to ban the sale of petrol and diesel vehicles by 2035. High adoption of electric vehicles could save Australian drivers $500 billion by 2035. While a slow uptake of electric vehicles would result in a 1 trillion cost to the Australian health system by 2050. Although air pollution would cause the deaths of at least 2500 people across Sydney and Melbourne in the year 2030, even if the federal government swiftly clamped down on poisonous car fuels. A Federal Government target for 100% of car sales to be electric vehicles before 2050 could also be included in the Federal Government's National Electric Vehicle Strategy. This is because Prime Minister Scott Morrison stated in 2021 that the government's goal is to reach net-zero emissions by 2050, which would require a national transition to 100% electric vehicles before 2050. 60% of Australians also want a net-zero emissions target by 2050. Scott Morrison will deliver a target for net-zero emissions by 2050 to the 2021 UN Climate Conference. The New South Wales treasurer, Matt Kean, said the federal Nationals should resign if they didn't support a national target for net-zero emissions by 2050. To reach net-zero emissions by 2050, electric vehicles will also need to represent 50% of car sales by 2035.
  • 1.7K
  • 15 Nov 2022
Topic Review
Biology and Ecology of Armeria maritima
Tolerance to heavy metals in plants is a model process used to study adaptations to extremely unfavorable environments. One species capable of colonizing areas with high contents of heavy metals is Armeria maritima (Mill.) Wild. A. maritima plants growing in metalliferous areas differ in their morphological features and tolerance levels to heavy metals compared to individuals of the same species growing in non-metalliferous areas. The Armeria maritima (A. maritima) adaptations to heavy metals occur at the organismal, tissue, and cellular levels (e.g., the retention of metals in roots, enrichment of the oldest leaves with metals, accumulation of metals in trichomes, and excretion of metals by salt glands of leaf epidermis). This species also undergoes physiological and biochemical adaptations (e.g., the accumulation of metals in vacuoles of the root’s tannic cells and secretion of such compounds as glutathione, organic acids, or HSP17). 
  • 1.7K
  • 29 Mar 2023
Topic Review
Energy Management and Control Techniques for Electric Vehicle
Electric vehicles (EVs) are universally recognized as an incredibly effective method of lowering gas emissions and dependence on oil for transportation. Electricity, rather than more traditional fuels like gasoline or diesel, is used as the main source of energy to recharge the batteries in EVs. Future oil demand should decline as a result of the predicted rise in the number of EVs on the road. The charging infrastructure is considered as a key element of EV technology where the recent research is mostly focused. A strong charging infrastructure that serves both urban and rural areas, especially those with an unstable or nonexistent electrical supply, is essential in promoting the global adoption of EVs.
  • 1.7K
  • 10 Aug 2023
Topic Review
Application of Through Glass Via Technology
Glass has emerged as a highly versatile substrate for various sensor and MEMS (microelectromechanical systems) packaging applications, including electromechanical, thermal, optical, biomedical, and RF devices, due to its exceptional properties such as high geometrical tolerances, outstanding heat and chemical resistance, excellent high-frequency electrical properties, and the ability to be hermetically sealed. In these applications, Through Glass Via (TGV) technology plays a vital role in manufacturing and packaging by creating electrical interconnections through glass substrates.
  • 1.7K
  • 18 Jan 2024
Topic Review
Development of the Cogeneration Sector in Spain
Combined Heat and Power (CHP) has been identified by the EU as a powerful resource capable of making substantial contributions to energy savings and reducing GHG emissions. Spain’s effort to promote CHP has been prolific since the 1980s. In this regard, there have been various Laws, Royal Decrees (RDs) and European Union (EU) Directives addressed to reach the national objectives set for the CHP sector. Despite these attempts, the evolution and growth of installed CHP capacity has been irregular, compared to other technologies. Likewise, the academic treatment of the Spanish CHP evolution has not deserved the same attention as other technologies such as wind, photovoltaic and thermal solar systems. As a result, this article is aimed at providing a comprehensive overview of the regulatory frameworks applied to the Spanish CHP sector and analysing the reasons behind the variable evolution of the installed CHP capacity.
  • 1.7K
  • 20 Feb 2024
Topic Review
Retinoic Acid and Stemness
Stem cells have the capacity of self-renewal and, through proliferation and differentiation, are responsible for the embryonic development, postnatal development, and the regeneration of tissues in the adult organism. Cancer stem cells, analogous to the physiological stem cells, have the capacity of self-renewal and may account for growth and recurrence of tumors. Development and regeneration of healthy tissues and tumors depend on the balance of different genomic and nongenomic signaling pathways that regulate stem cell quiescence, proliferation, and differentiation. During evolution, this balance became dependent on all-trans retinoic acid (RA), a molecule derived from the environmental factor vitamin A. 
  • 1.7K
  • 22 Sep 2021
Topic Review
The Classification of Fraudulent Bank Transactions
The modern financial sector requires high security standards due to rapid technological progress. Banks utilize many security measures for transactions, including artificial intelligence (AI), neural networks, and machine learning. The use of these techniques allows advanced technological problems to be solved. The most common types of financial frauds are money laundering, identity fraud, and credit and debit card frauds.
  • 1.7K
  • 11 Jul 2023
Topic Review
Steel Fibers on Tensile Properties of Ultra-High-Performance Concrete
Ultra-high-performance concrete (UHPC) is an advanced cement-based material with excellent mechanical properties and durability. However, with the improvement of UHPC’s compressive properties, its insufficient tensile properties have gradually attracted attention.
  • 1.7K
  • 11 Mar 2024
Topic Review
Chitosan and its Derivatives
Chitosan (CS) is a hemi-synthetic cationic linear polysaccharide produced by the deacetylation of chitin. CS is non-toxic, highly biocompatible, and biodegradable, and it has a low immunogenicity. Additionally, CS has inherent antibacterial properties and a mucoadhesive character and can disrupt epithelial tight junctions, thus acting as a permeability enhancer. As such, CS and its derivatives are well-suited for the challenging field of ocular drug delivery. In the present review article, we will discuss the properties of CS that contribute to its successful application in ocular delivery before reviewing the latest advances in the use of CS for the development of novel ophthalmic delivery systems. Colloidal nanocarriers (nanoparticles, micelles, liposomes) will be presented, followed by CS gels and lenses and ocular inserts. Finally, instances of CS coatings, aiming at conferring mucoadhesiveness to other matrixes, will be presented.
  • 1.7K
  • 31 Jul 2020
Topic Review
Tungurahua Volcano (Ecuador)
Since April of 2015, the ash dispersion and ash fallout due to Vulcanian eruptions at Tungurahua, one of the most active volcanoes in Ecuador, have been forecasted daily. For this purpose, our forecasting system uses the meteorological Weather Research and Forecasting (WRF) and the FALL3D models. Previously, and based on field data, laboratory, and numerical studies, corresponding eruption source parameters (ESP) have been defined. We analyzed the historically forecasted results of the ash fallout quantities over four years (April 2015 to March 2019), in order to obtain the average isomass and probability maps for three-month periods: February–March–April (FMA), May–June–July (MJJ), August–September–October (ASO), and November–December–January (NDJ). Our results indicate similar ash fallout shapes during MJJ and ASO, with a clear and defined tendency toward the west of the volcano; this tendency is less defined during NDJ and FMA. The proximal region west of the volcano (about 100 km to the west) has the highest probability (>70%) of being affected by ash fallout. The distant region to the west (more than 100 km west) presented low to medium probabilities (10%–70%) of ash fallout. The cities of Guaranda (W, 60% to 90%), Riobamba (SW, 70%), and Ambato (NW, 50% to 60%) have the highest probabilities of being affected by ash fallout. Among the large Ecuadorian cities, Guayaquil (SW, 10% to 30%) has low probability, and Quito (N, ≤5%) and Cuenca (SSE, <5%) have very low probabilities of being affected by ash fallout. High ash clouds can move in different directions, compared to wind transport near the surface. Therefore, it is possible to detect ash clouds by remote sensing which, in Ecuador, is limited to the layers over the meteorological clouds, which move in a different direction than low wind; the latter produces ash fallout over regions in different directions compared to the detected ash clouds. In addition to the isomass/probability maps and detected ash clouds, forecasting is permanently required in Ecuador.
  • 1.7K
  • 21 Aug 2020
Topic Review
Sec61
The heterotrimeric Sec61 complex of the ER membrane represents the major entry point for precursor polypeptides into the membrane or lumen of the ER. It forms a polypeptide-conducting channel, who's gating (i.e. opening and closing) involves various interactions partners. Mutations in the genes, which are coding for the Sec61 subunits or their interaction partners, can cause diseases (termed Sec61-channelopathies).
  • 1.7K
  • 02 Sep 2025
Topic Review
Circular Carbon Economy (CCE)
The circular carbon economy (CCE) system achieves a balance by closing the carbon circle, capturing CO2emissions, and using them economically after their initial linear use. This approach differs in that it does not focus solely on reducing or avoiding the increase in the amounts of carbon. The steady increase in carbon dioxide levels requires increased effort to mitigate their impact.
  • 1.7K
  • 10 Nov 2021
Topic Review
Interleukin (IL)-4 and IL-13 in Inflammatory Arthritis
Interleukin (IL)-4 and IL-13 belong to the T helper 2 (Th2) cytokine family, along with IL-3, IL-5, and IL-9. These cytokines are key mediators of allergic inflammation. 
  • 1.7K
  • 07 Dec 2021
Topic Review
Seed Amplification Assays for α-Synuclein
Various disease-associated forms or strains of α-synuclein (αSynD) can spread and accumulate in a prion-like fashion during synucleinopathies such as Parkinson’s disease (PD), Lewy body dementia (DLB), and multiple system atrophy (MSA). This capacity for self-propagation has enabled the development of seed amplification assays (SAAs) that can detect αSynD in clinical samples. Notably, α-synuclein real-time quaking-induced conversion (RT-QuIC) and protein misfolding cyclic amplification (PMCA) assays have evolved as ultrasensitive, specific, and relatively practical methods for detecting αSynD in a variety of biospecimens including brain tissue, CSF, skin, and olfactory mucosa from synucleinopathy patients.  
  • 1.7K
  • 22 Apr 2022
Topic Review
Mineralizing Fluids at Porphyry Deposits of Cu−Mo−Au System
The porphyry type of hydrothermal mineral deposits is of paramount economic importance because deposits of this type host much of the world’s reserves of Cu, Mo, and Re, as well as much Re and remarkable reserves of critical elements such as Ag, Pd, Te, Se, Bi, Zn, and Pb. Porphyry deposits are conventionally classified into mineralogical–geochemical types according to their dominant valuable components. The most economically important porphyry-type deposits are those of the Cu (Au), Cu–Mo (Au), Mo, and Au types.
  • 1.7K
  • 05 May 2022
Topic Review
Agri-Food Wastes for Bioplastics
Agri-food wastes (such as brewer’s spent grain, olive pomace, residual pulp from fruit juice production, etc.) are produced annually in very high quantities posing a serious problem, both environmentally and economically. These wastes can be used as secondary starting materials to produce value-added goods within the principles of the circular economy. Agri-food waste is produced in large quantities and derives from many sources (from breweries, from the pressing of olives, from the production of fruit and vegetables, etc.). Consequently, the problem of their disposal arises both from the point of view of costs and means. However, precisely because these wastes represent a great added value for the substances they contain and which can be exploited, it is profitable to reuse and recycle them.
  • 1.7K
  • 20 Sep 2022
Topic Review
Lignin as Renewable Building Block for Sustainable Polyurethanes
Lignin, being a natural aromatic polymer rich in functional hydroxyl groups, has been drawing the interest of academia and industry for its valorization, especially for the development of polymeric materials. Among the different types of polymers that can be derived from lignin, polyurethanes (PUs) are amid the most important ones, especially due to their wide range of applications. Lignin, being a natural aromatic polymer rich in functional hydroxyl groups, has been drawing the interest of academia and industry for its valorization, especially for the development of polymeric materials. Among the different types of polymers that can be derived from lignin, polyurethanes (PUs) are amid the most important ones, especially due to their wide range of applications. 
  • 1.7K
  • 20 Oct 2022
Topic Review
Positive and Negative Affect Schedule
The Positive and Negative Affect Schedule (PANAS) is a self-report questionnaire that consists of two 10-item scales to measure both positive and negative affect. Each item is rated on a 5-point scale of 1 (not at all) to 5 (very much). The measure has been used mainly as a research tool in group studies, but can be utilized within clinical and non-clinical populations as well. Shortened, elongated, and children's versions of the PANAS have been developed, taking approximately 5–10 minutes to complete. Clinical and non-clinical studies have found the PANAS to be a reliable and valid instrument in the assessment of positive and negative affect.
  • 1.7K
  • 28 Oct 2022
Topic Review
Oxidative Stress in Chronic Obstructive Pulmonary Disease
Since chronic obstructive pulmonary disease (COPD) is a heterogeneous disease, a specific anti-inflammatory therapy for this disease has not been established yet. Oxidative stress is recognized as a major predisposing factor to COPD related inflammatory responses, resulting in pathological features of small airway fibrosis and emphysema. 
  • 1.7K
  • 06 Feb 2023
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