Your browser does not fully support modern features. Please upgrade for a smoother experience.
Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort by:
Most Viewed Latest Alphabetical (A-Z) Alphabetical (Z-A)
Filter:
All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review
Gamma-Sarcoglycanopathy
Limb-girdle muscular dystrophies (LGMDs) represent a group of muscle diseases due to monogenic mutations encoding muscle proteins that are defective for heterozygous and homozygous mutations prevalent in certain regions.
  • 1.8K
  • 20 Apr 2023
Topic Review
Deep Learning Approaches for Wildfires Using Satellite Data
Wildland fires are one of the most dangerous natural risks, causing significant economic damage and loss of lives worldwide. Every year, millions of hectares are lost, and experts warn that the frequency and severity of wildfires will increase in the coming years due to climate change. To mitigate these hazards, numerous deep learning models were developed to detect and map wildland fires, estimate their severity, and predict their spread. In this paper, we provide a comprehensive review of recent deep learning techniques for detecting, mapping, and predicting wildland fires using satellite remote sensing data. We begin by introducing remote sensing satellite systems and their use in wildfire monitoring. Next, we review the deep learning methods employed for these tasks, including fire detection and mapping, severity estimation, and spread prediction. We further present the popular datasets used in these studies. Finally, we address the challenges faced by these models to accurately predict wildfire behaviors, and suggest future directions for developing reliable and robust wildland fire models.
  • 1.8K
  • 24 May 2023
Topic Review
Sport and Abuse in Uganda
Uganda, officially known as the Republic of Uganda, is a landlocked country in east central Africa and is one of the 49 sub-Saharan countries. It is bordered by Kenya in the east, the Democratic Republic of Congo in the west, South Sudan in the north and Tanzania and Rwanda in the south and southwest, respectively. It is also known as the ‘Pearl of Africa’, which is an expression affiliated to Winston Churchill who used it to describe the country’s flora and fauna. There are 49 ethnic groups in Uganda.
  • 1.8K
  • 10 Nov 2023
Topic Review
AMP-activated Protein Kinase
We live and to do so we must breathe and eat, so are we a combination of what we eat and breathe? Here we will consider this question, and the role in this respect of the AMP-activated protein kinase (AMPK). Emerging evidence suggests that AMPK facilitates central and peripheral reflexes that coordinate breathing and oxygen supply, and contributes to central regulation of feeding and food choice. We propose, therefore, that oxygen supply to the body is aligned with not only the quantity we eat, but also nutrient-based diet selection, and that the cell-specific expression pattern of AMPK subunit isoforms is critical to appropriate system alignment in this respect. If this is the case, then aberrant cell-specific changes in the expression of AMPK subunit isoforms could give rise, in part, to known associations between a wide variety of conditions associated with metabolic disorder.
  • 1.8K
  • 10 May 2021
Topic Review
Nonlinear Damping Identification
In recent decades, nonlinear damping identification (NDI) in structural dynamics has attracted wide research interests and intensive studies. Different NDI strategies, from conventional to more advanced, have been developed for a variety of structural types. With apparent advantages over classical linear methods, these strategies are able to quantify the nonlinear damping characteristics, providing powerful tools for the analysis and design of complex engineering structures.
  • 1.8K
  • 05 Jan 2021
Topic Review
Târnave Vineyard
Located at the intersection of the geographical coordinates of 46°–47° Northern latitude and 23°–24° Eastern longitude, Târnave vineyards are part of the viticultural zone 1 of Romania. They are situated on the Transylvanian Plateau. The most significant viticultural area of Transylvania, the prestigious Târnave vineyard, named so because most of the vineyards are located on the slopes that delineate the valleys of the rivers Târnava Mare and Târnava Mică, is known and appreciated for its quality wines with a specific flavor and a good sugar/acidity balance.
  • 1.8K
  • 11 Aug 2021
Topic Review
Chemical and Cell-Based Antioxidant Assays
Antioxidants remain interesting molecules of choice for suppression of the toxic effects of free radicals in foods and human systems. The current practice involves the use of mainly synthetic molecules as potent antioxidant agents. However, due to the potential negative impact on human health, there is an intensive effort within the research community to develop natural alternatives with similar antioxidant efficacy but without the negative side effects of synthetic molecules. Still, the successful development of new molecules depends on the use of reliable chemical or cell culture assays to screen antioxidant properties. Chemical antioxidant assays include the determination of scavenging ability against free radicals such as DPPH, superoxide anion radicals, hydroxyl radicals, hydrogen peroxide, and nitric oxide. Other antioxidant tests include the ability of compounds to bind and sequester prooxidant metal cations, reduce ferric iron, and attenuate the rate of lipid oxidation. Ex vivo tests utilize cell cultures to confirm entry of the molecules into cells and the ability to quench synthetic intracellular free radicals or to stimulate the increased biosynthesis of endogenous antioxidants.
  • 1.8K
  • 19 Aug 2021
Topic Review
Extended Theory of Planned Behavior
First described by Ajzen in 1985, the Theory of Planned Behavior (TPB) is one of the most widely used theories to predict and explain behavioral intentions and behavior. According to the TPB, attitude, subjective norm and perceived behavioral control towards a certain behavior determine the intention to perform this behavior. In relation to our study, attitude describes the extent to which student teachers evaluate the implementation of ESD in schools as positive or negative. The subjective norm refers to the perceived social pressure that important reference people from professional or private life expect ESD implementation in their work as teachers. Perceived behavioral control describes the perceived control of actually being able to implement ESD in schools.
  • 1.8K
  • 26 Aug 2021
Topic Review
Impacts of Drugs on Skeleton in Forensic Anthropology
Forensic anthropologists rely on a number of parameters when analyzing human skeletal remains to assist in the identification of the deceased, predominantly age-at-death, sex, stature, ancestry or population affinity, and any unique identifying features. During the examination of human remains, it is important to be aware that the skeletal features considered when applying anthropological methods may be influenced and modified by a number of factors, prescription drugs (including medical and non-medical use) and other commonly used drugs. Through different mechanisms, drugs can alter bone mineral density, causing osteopenia, osteoporosis, increase the risk of fractures, osteonecrosis, and oral changes.
  • 1.8K
  • 22 Apr 2022
Topic Review
Savoia-Marchetti SM.75
The Savoia-Marchetti SM.75 was an Italian passenger and military transport aircraft of the 1930s and 1940s. It was a low-wing, trimotor monoplane of mixed metal and wood construction with a retractable tailwheel undercarriage. It was the last of a line of transport aeroplanes that Alessandro Marchetti began building in the early 1930s. The SM.75 was fast, robust, capable of long-range flight and could carry up to 24 passengers for 1,000 miles.
  • 1.8K
  • 24 Oct 2022
Topic Review
List of Metric Units
Metric units are units based on the metre, gram or second and decimal (power of ten) multiples or sub-multiples of these. The most widely used examples are the units of the International System of Units (SI). By extension they include units of electromagnetism from the CGS and SI units systems, and other units for which use of SI prefixes has become the norm. Other unit systems using metric units include:
  • 1.8K
  • 27 Oct 2022
Topic Review
Diverticulosis
Diverticulosis is the condition of having multiple pouches (diverticula) in the colon that are not inflamed. These are outpockets of the colonic mucosa and submucosa through weaknesses of muscle layers in the colon wall, and may be due in part to low-fiber diet prompting changes in intestinal microflora with consequent low-grade inflammation. Diverticula do not cause symptoms in most people. Diverticular disease occurs when diverticula become clinically inflamed, a condition known as diverticulitis. Diverticula typically occur in the sigmoid colon, which is commonplace for increased pressure. The left side of the colon is more commonly affected in the United States while the right side is more commonly affected in Asia. Diagnosis is often during routine colonoscopy or as an incidental finding during CT scan. It is common in Western countries with about half of those over the age of 60 affected in Canada and the United States. Diverticula are uncommon before the age of 40, and increase in incidence beyond that age. Rates are lower in Africa; the reasons for this remain unclear but may involve the greater prevalence of a high fiber diet in contrast with the lower-fiber diet characteristic of many Western populations.
  • 1.8K
  • 10 Nov 2022
Topic Review
Heat Shock Proteins in Cellular Homeostasis
Heat shock proteins (Hsps) are a family of ubiquitously expressed stress proteins and extrinsic chaperones that are required for viability and cell growth in all living organisms. These proteins are highly conserved and produced in all cellular organisms when exposed to stress. Hsps play a significant role in protein synthesis and homeostasis, as well as in the maintenance of overall health in crustaceans against various internal and external environmental stresses. Recent reports have suggested that enhancing in vivo Hsp levels via non-lethal heat shock, exogenous Hsps, or plant-based compounds, could be a promising strategy used to develop protective immunity in crustaceans against both abiotic and biotic stresses.
  • 1.8K
  • 29 Nov 2022
Topic Review
mRNA Localization to the Endoplasmic Reticulum by Zipcodes
Subcellular mRNA localization is an evolutionarily conserved mechanism to spatially and temporally drive local translation and, in turn, protein targeting. Hence, this mechanism achieves precise control of gene expression and establishes functional and structural networks during cell growth and development as well as during stimuli response. Since its discovery in ascidian eggs, mRNA localization has been extensively studied in animal and yeast cells. mRNA localization to the endoplasmic reticulum (ER) has also been well established since its discovery in cereal endosperm cells in the early 1990s. Storage protein mRNA targeting to distinct subdomains of the ER determines efficient accumulation of the corresponding proteins in different endosomal storage sites and, in turn, underlies storage organelle biogenesis in cereal grains. The targeting process requires the presence of RNA localization elements, also called zipcodes, and specific RNA-binding proteins that recognize and bind these zipcodes and recruit other factors to mediate active transport.
  • 1.8K
  • 24 Nov 2022
Topic Review
Analysis of Optical Coherence Tomography Images
Optical coherence tomography (OCT) is a noninvasive imaging technique that provides high-resolution cross-sectional retina images, enabling ophthalmologists to gather crucial information for diagnosing various retinal diseases. The images acquired from the patients in raw format might be associated with poor contrast, noise, low light, and other artefacts. Several image enhancement techniques are needed to extract useful information. Several approaches can be used to enhance the quality of the OCT image, such as denoising the images to classify diseases through pathologies segmentation.
  • 1.8K
  • 06 Apr 2023
Topic Review
Telocytes
Telocytes/CD34+ stromal cells in the normal and pathological peripheral nervous system (PNS). We consider the following aspects: (A) general characteristics of telocytes; (B) the presence, characteristics and arrangement of telocytes in the normal PNS, including i) nerve epi-perineurium and endoneurium (e.g., telopodes extending into the endoneurial space); ii) sensory nerve endings (e.g., Meissner and Pacinian corpuscles, and neuromuscular spindles); iii) ganglia; and iv) the intestinal autonomic nervous system; (C) the telocytes in the pathologic PNS, encompassing (i) hyperplastic neurogenic processes (neurogenic hyperplasia of the appendix and gallbladder), highly demonstrative of telocyte characteristics and relations, (ii) PNS tumours, such as neurofibroma, schwannoma and granular cell tumour. 
  • 1.8K
  • 26 Oct 2020
Topic Review
G-Quadruplexes: Emerging Anticancer Roles
G-quadruplexes, a family of (thermodynamically and kinetically stable) tetraplex helices, are non-canonical secondary structures derived from guanine (G)-rich sequences of nucleic acids. G-quadruplexes were found to occur in functionally-important regions of the human genome, including the telomere tandem sequences, several proto-oncogene promoters and other regulatory regions, ribosomal DNA (rDNA), as well as mRNA sequences encoding for proteins with roles in tumorigenesis, thus establishing a clear connection between G-quadruplexes and known hallmarks of cancer. Stabilization of G-quadruplexes belonging to the above categories, by means of small-molecule intervention, has been correlated with a range of anticancer effects, which has led to classifying G-quadruplexes as novel potential targets in anticancer research. The most common ways in which G-quadruplexes are now understood to serve in an anticancer capacity are presented herein.
  • 1.8K
  • 03 Mar 2021
Topic Review
Quenchbody
The detection of viruses, disease biomarkers, physiologically active substances, drugs, and chemicals is of great significance in many areas of our lives. Immunodetection technology is based on the specificity and affinity of antigen–antibody reactions. Compared with other analytical methods such as liquid chromatography coupled with mass spectrometry, which requires a large and expensive instrument, immunodetection has the advantages of simplicity and good selectivity and is thus widely used in disease diagnosis and food/environmental monitoring. Quenchbody (Q-body), a new type of fluorescent immunosensor, is an antibody fragment labeled with fluorescent dyes. When the Q-body binds to its antigen, the fluorescence intensity increases. The detection of antigens by changes in fluorescence intensity is simple, easy to operate, and highly sensitive.
  • 1.8K
  • 20 Apr 2021
Topic Review
Lactobacillus plantarum GKM3
In age-accelerated SAMP8 mouse model, GKM3 groups showed significantly increased latency in the passive avoidance test and time of successful avoidance in the active avoidance test. The TBARS and 8-OHdG from the aged mice brains also showed a significant reduction in the groups treated with GKM3. In addition, lower accumulation of the amyloid-β protein was found in SAMP8 mice brains with the supplement of GKM3. These results indicated that L. plantarum GKM3 delayed the process of aging, alleviated age-related cognitive impairment, and reduced oxidative stress.
  • 1.8K
  • 30 Aug 2021
Topic Review
Flagellum/Stigma in Euglena gracilis
Cell division of unicellular microalgae is a fascinating process of proliferation, at which whole organelles are regenerated and distributed to two new lives. We performed dynamic live cell imaging of Euglena gracilis using optical microscopy to elucidate the mechanisms involved in the regulation of the eyespot and flagellum during cell division and distribution of the organelles into the two daughter cells. Single cells of the wild type (WT) and colorless SM-ZK cells were confined in a microfluidic device, and the appearance of the eyespot (stigma) and emergent flagellum was tracked in sequential video-recorded images obtained by automatic cell tracking and focusing. We examined 12 SM-ZK and 10 WT cells and deduced that the eyespot diminished in size and disappeared at an early stage of cell division and remained undetected for 26–97 min (62 min on average, 22 min in deviation). Subsequently, two small eyespots appeared and were distributed into the two daughter cells. Additionally, the emergent flagellum gradually shortened to zero-length, and two flagella emerged from the anterior ends of the daughter cells. Our observation revealed that the eyespot and flagellum of E. gracilis are degraded once in the cell division, and the carotenoids in the eyespot are also decomposed. Subsequently, the two eyespots/flagella are regenerated for distribution into daughter cells. As a logical conclusion, the two daughter cells generated from a single cell division possess the equivalent organelles and each E. gracilis cell has eternal or non-finite life span. The two newly regenerated eyespot and flagellum grow at different rates and mature at different timings in the two daughter cells, resulting in diverse cell characteristics in E. gracilis.
  • 1.8K
  • 05 Nov 2021
  • Page
  • of
  • 2799
Featured Entry Collections
>>

Featured Reprints

>>
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Encyclopedia of Engineering
Encyclopedia of Social Sciences
Encyclopedia of Medieval Royal Iconography
Academic Video Service
Feedback