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Topic Review
Optic Flow in Postural Control
Optic flow stimuli are crucial for the control of stance in the upright position. The visual control of posture has recently received a lot of interest from several researchers. One of the most intriguing aspects is the contribution of the different parts of the visual field in the control of stance.
  • 1.4K
  • 17 Jun 2021
Topic Review
Latin-American Genes in Rheumatoid Arthritis
The successful implementation of personalized medicine will rely on the integration of information obtained at the level of populations with the specific biological, genetic, and clinical characteristics of an individual. However, because genome-wide association studies tend to focus on populations of European descent, there is a wide gap to bridge between Caucasian and non-Caucasian populations before personalized medicine can be fully implemented, and rheumatoid arthritis (RA) is not an exception. In this review, we discuss advances in our understanding of genetic determinants of RA risk among global populations, with a focus on the Latin American population. Geographically restricted genetic diversity may have important implications for health and disease that will remain unknown until genetic association studies have been extended to include Latin American and other currently under-represented ancestries. The next few years will witness many breakthroughs in personalized medicine, including applications for common diseases and risk stratification instruments for targeted prevention/intervention strategies. Not all of these applications may be extrapolated from the Caucasian experience to Latin American or other under-represented populations.
  • 1.4K
  • 04 Nov 2020
Topic Review
Honey Bee Colony Losses
Various factors have been considered to be contributing to honey bee losses, and recent investigations have established some of the most important ones, in particular, pests and diseases, bee management, including bee keeping practices and breeding, the change in climatic conditions, agricultural practices, and the use of pesticides. The global picture highlights the ectoparasitic mite Varroa destructor as a major factor in colony loss. Last but not least, microsporidian parasites, mainly Nosema ceranae, also contribute to the problem. Thus, it is obvious that there are many factors affecting honey bee colony losses globally. Increased monitoring and scientific research should throw new light on the factors involved in recent honey bee colony losses.
  • 1.4K
  • 16 Nov 2020
Topic Review
HMM and SBA Porous Materials
Mesoporous silicas have enjoyed great interest among scientists practically from the moment of their discovery thanks to their unique attractive properties. Many types of mesoporous silicas have been described in literature, the most thoroughly MCM-41 and SBA-15 ones. The methods of syntheses, characterization and use of mesoporous silicas from SBA (Santa Barbara Amorphous) and HMM (Hybrid Mesoporous Materials) groups are presented. The first group is represented by (i) SBA-1 of three-dimensional cubic structure and (ii) SBA-2 of three-dimensional combined hexagonal and cubic structures. The HMM group is represented by (i) HMM-1 of two-dimensional hexagonal structure and (ii) HMM-2 of three-dimensional structure. The paper provides comprehensive information on the above-mentioned silica materials available so far, also including the data for the silicas modified with metal ions or/and organic functional groups and examples of the materials applications.
  • 1.4K
  • 18 Mar 2021
Topic Review
Metabolic-(Dysfunction) Associated Fatty Liver Disease
Metabolic- (dysfunction) associated fatty liver disease (MAFLD) represents the predominant hepatopathy and one of the most important systemic, metabolic-related disorders all over the world associated with severe medical and socio-economic repercussions due to its growing prevalence, clinical course (steatohepatitis and/or hepatocellular-carcinoma), and related extra-hepatic comorbidities. 
  • 1.4K
  • 01 Jun 2021
Topic Review
Antisense Oligonucleotides for Vaccine Improvement
Antisense oligonucleotides (ASOs) are synthetically prepared short single-stranded deoxynucleotide sequences that have been validated as therapeutic agents and as a valuable tool in molecular driving biology. ASOs can block the expression of specific target genes via complementary hybridization to mRNA. Due to their high specificity and well-known mechanism of action, there has been a growing interest in using them for improving vaccine efficacy. Several studies have shown that ASOs can improve the efficacy of vaccines either by inducing antigen modification such as enhanced expression of immunogenic molecules or by targeting certain components of the host immune system to achieve the desired immune response. However, despite their extended use, some problems such as insufficient stability and low cellular delivery have not been sufficiently resolved to achieve effective and safe ASO-based vaccines.
  • 1.4K
  • 07 Jun 2021
Topic Review
Emotion Regulation in Autobiographical Memories
When facing a negative event, people implement different strategies to regulate ongoing emotions. Although the previous literature has suggested that the emotional intensity of a negative episode is associated with the characteristics of the subsequent autobiographical memory, it is still unknown whether emotion regulation (ER) moderates this relationship. In the present study, we provided undergraduate students with a smartphone-based diary to report a negative episode immediately after its occurrence and rate the momentary use of two ER strategies: cognitive reappraisal and rumination. To explore autobiographical memory, two “surprise” recall tasks were performed one week and one month after the event. According to the results, cognitive reappraisal was linked with better memory performances, and a tendency to retrospectively underestimate the negativity of highly intense events was observed only in participants adopting high rates of this strategy. Conversely, intense rumination was found to be associated with less detailed memories of emotionally intense events, as well as with higher emotional involvement with negative episodes over time, regardless of their intensity. The results support the maladaptive role of rumination and the adaptive influence of cognitive reappraisal on autobiographical memory. 
  • 1.4K
  • 16 Jul 2021
Topic Review
Lattice Boltzmann Method
Biofilm growth and evolution are very complex interactions among physicochemical and biological processes. Mathematical models are critical to modern biotechnology—both in research and in the engineering practice. Thus, many models of biofilms have been developed to include various biofilm reactor modules. However, considerable challenges exist in modelling microbial processes where mesoscopic dynamics of nutrient transport must be coupled with microscopic bacteria growth and their elementary biochemical reactions at reactive or enzymatic interfaces, in addition to the microbiological and/or ecological aspects of the “micro” organisms involved in biofilms. Lattice Boltzmann Method (LBM) treats flows in terms of fictive parcels of particles which reside on a mesh and conduct translation according to collision steps entailing overall fluid-like behavior. The goal of this review is to discuss and identify the opportunities of applying different LBM-based models to specific areas of biofilm research as well as unique challenges that LBM-based models must overcome.
  • 1.4K
  • 19 Jul 2021
Topic Review
Zebrafish Motile Cilia
Zebrafish is a vertebrate teleost widely used in many areas of research. As embryos, they develop quickly and provide unique opportunities for research studies owing to their transparency for at least 48 h post fertilization. Zebrafish have many ciliated organs that include primary cilia as well as motile cilia. Using zebrafish as an animal model helps to better understand human diseases such as Primary Ciliary Dyskinesia (PCD), an autosomal recessive disorder that affects cilia motility, currently associated with more than 50 genes. 
  • 1.4K
  • 22 Sep 2021
Topic Review
Nano-Sized Energetic Materials (nEMs)
As a hot research topic, nano-scale energetic materials (nEMs) have recently attracted much attention in the fields of energy storage and release, catalysis, and adsorption, owing to their unique large specific surface areas (SSA) and extraordinary properties, as the structures, compositions, sizes, and shapes vary on the atomic and molecular scale.
  • 1.4K
  • 05 Jan 2022
Topic Review
Intestinal Organoids
Following advances in primary cell culture techniques, organoids have been developed. Such technological breakthroughs have opened a new path in the study of microbial infectious diseases, and thus opened onto new strategies to control foodborne hazards. 
  • 1.4K
  • 07 Jan 2022
Topic Review
Tumor Necrosis Factor and Lymphotoxin
The tumor necrosis factor (TNF) ligand family includes 19 ligands, which each contain a C-terminal TNF homology domain (THD). Each ligand binds to one or multiple TNF receptors (TNFR), containing extracellular cysteine-rich domains (CRD) for ligand binding. Tumor necrosis factor (TNF or TNF-α) and lymphotoxin (LT) are the first two cytokines that have been characterized as TNF superfamily members. They have a homologous amino acid sequence and were both discovered based on their anti-tumor effects. Moreover, both ligands bind to TNF receptor type 1 and type 2 (TNFR1 and TNFR2) and mediate similar cell signaling transduction.
  • 1.4K
  • 19 Jan 2022
Topic Review
Perfluoropyridine
The fluorine atom exhibits many unique properties, including a small atomic radius, large electronegativity, and minimal polarizability. Thus, when coupled with carbon in the form of a C-F bond, organofluorine compounds with highly sought after properties can be obtained. Perfluoropyridine (PFPy) is an organofluorine compound that has been employed for a variety of applications, from straightforward chemical synthesis to more advanced functions, such as fluorinated networks and polymers. This can be directly attributed to the highly reactive nature of PFPy, especially towards nucleophilic aromatic substitution (SNAr).
  • 1.4K
  • 10 Mar 2022
Topic Review
Mineralogy and Geochemistry of Ferromanganese Crusts
Late Pleistocene–Holocene rocks from the western part of Cocos-Nazca Spreading Centre (C-NSC) include ferromanganese crusts that elucidate the geochemistry and mineralogy of a deep-sea geological setting. Geochemical, mineralogical and petrological signatures indicate complex formation influenced by mild hydrothermal processes. These crusts consist mostly of mixed birnessite, todorokite-buserite, and Mn-(Fe) vernadite with traces of diagenetic manganates (asbolane), Fe-oxides and oxyhydroxides or hydrothermally associated and relatively pure Mn-oxyhydroxides (manganite). The average Mn/Fe ratio is 2.7, which suggests predominant mixed hydrogenous-early diagenetic crusts with hydrothermal influences. The mean concentrations of three prospective metals (Ni, Cu and Co) are low: 0.17, 0.08 and 0.025 wt %, respectively. The total content of ΣREY is also low, and ranges from 81 to 741 mg/kg (mean 339 mg/kg).
  • 1.4K
  • 27 May 2022
Topic Review
Timeline of Yellow Fever
This is a timeline of yellow fever. Major events such as historical epidemics and medical developments are described.
  • 1.4K
  • 03 Nov 2022
Topic Review
Live Streaming World News
Live streaming world news refers to live videos streams of world television news which are provided via streaming television or via streaming media by various television networks and television news outlets, from various countries. These are provided through Smart TV, or else through the networks' own websites, or also possibly via internet television, especially YouTube, or via video on demand services, subscription video on demand websites such as e.g. Hulu, mobile apps, or digital media players that are designed to play streaming television, such as e.g. the Roku media player. It is distinct from news broadcasts that are transmitted via conventional broadcast television; since it is not transmitted via cable television services, and not via over-the-air television that is transmitted via over-the-air broadcasting. For some twenty-four-hour news channels, the content being shown via its streaming news service, and via its broadcast television channels, may be identical; however, for regular commercial networks, the content of the streaming news may be quite different than what is being broadcast; i.e. the broadcast channels may carry standard television entertainment, while the streaming service is devoted to news only. One example of this is the ABC Network of the United States, and its streaming online news service.
  • 1.4K
  • 02 Dec 2022
Topic Review
Virtual Collection for Distributed Photovoltaic Data
With the rapid development of distributed photovoltaic systems (DPVS), the shortage of data monitoring devices and the difficulty of comprehensive coverage of measurement equipment has become more significant, bringing great challenges to the efficient management and maintenance of DPVS. Virtual collection is a new DPVS data collection scheme with cost-effectiveness and computational efficiency that meets the needs of distributed energy management but lacks attention and research.
  • 1.4K
  • 08 Dec 2022
Biography
Peter L. Jensen
Peter Laurits Jensen (16 May 1886 – 26 October 1961) was a Danish American engineer, inventor and entrepreneur. He founded Magnavox Company and Jensen Radio Manufacturing Company. Peter Laurits Jensen was born on the island of Falster in Denmark during 1886. His education was in Danish high schools from which he graduated in 1902. He attended Amherst College in Massachusetts and graduated w
  • 1.4K
  • 27 Dec 2022
Topic Review
Enhanced Heat Transfer Technology for Helium–Xenon Gas Mixtures
As one of the most promising working substances for space nuclear power sources, research on the heat transfer characteristics of helium–xenon gas mixtures has become the key issue in focus. The ultimate goal is to improve the heat transfer efficiency of helium–xenon mixture in space nuclear power supply.
  • 1.4K
  • 29 Dec 2022
Topic Review
Development, Phenotypes, and Functional Characteristics of Eosinophil Lineage
The existence of eosinophils was documented histopathologically in the first half of the 19th century. However, the term “eosinophils” was first used by Paul Ehrlich in 1878. Since their discovery and description, their existence has been associated with asthma, allergies, and antihelminthic immunity. Eosinophils may also be responsible for various possible tissue pathologies in many eosinophil-associated diseases. 
  • 1.4K
  • 10 Apr 2023
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