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Topic Review
Microbiota–Gut–Brain Axis in Mood Disorders
The microbiota–gut–brain axis is a bidirectional communication pathway that enables the gut microbiota to communicate with the brain through direct and indirect signaling pathways to influence brain physiology, function, and even behavior. Several taxonomic changes in the gut microbiota have been reported in neurodevelopmental disorders, mood disorders such as anxiety and depression, and neurodegenerative disorders such as Alzheimer’s disease. 
  • 1.6K
  • 17 Feb 2022
Topic Review
Infrared Spectroscopy Technology
Food or raw materials themselves contain substances that may endanger human health and are called toxic and harmful substances in food, which can be divided into endogenous, exogenous toxic, and harmful substances and biological toxins. Therefore, realizing the rapid, efficient, and nondestructive testing of toxic and harmful substances in food is of great significance to ensure food safety and improve the ability of food safety supervision. Among the nondestructive detection methods, infrared spectroscopy technology has become a powerful solution for detecting toxic and harmful substances in food with its high efficiency, speed, easy operation, and low costs, while requiring less sample size and is nondestructive, and has been widely used in many fields.
  • 1.6K
  • 31 Mar 2022
Topic Review
Carbon Nanotube Based High Performance Biosensing Platform
After the COVID-19 pandemic, the development of an accurate diagnosis and monitoring of diseases became a more important issue. In order to fabricate high-performance and sensitive biosensors, many researchers and scientists have used many kinds of nanomaterials such as metal nanoparticles (NPs), metal oxide NPs, quantum dots (QDs), and carbon nanomaterials including graphene and carbon nanotubes (CNTs). Among them, CNTs have been considered important biosensing channel candidates due to their excellent physical properties such as high electrical conductivity, strong mechanical properties, plasmonic properties, and so on. 
  • 1.6K
  • 26 Sep 2022
Topic Review
Shark Barrier
A shark barrier (otherwise known as a "shark-proof enclosure" or "beach enclosure") is seabed-to-surface protective barrier that is placed around a beach to protect people from shark attacks. Often confused with shark nets, shark barriers form a fully enclosed swimming area that prevents sharks from entering (nets aim to reduce shark populations). Shark barrier design has evolved from rudimentary fencing materials to netted structures held in place with buoys and anchors. Recent designs have used plastics to increase strength, versatility and to reduce the environmental damage of bycatch.
  • 1.6K
  • 27 Sep 2022
Topic Review
Orthodontically Induced Inflammatory Root Resorption
Orthodontically induced inflammatory root resorption (OIIRR) is considered an undesired and inevitable complication induced by orthodontic forces. This inflammatory mechanism is regulated by immune cells that precede orthodontic tooth movement (OTM) and can influence the severity of OIIRR. OIIRR occurs on almost all tooth roots exposed to orthodontic forces.
  • 1.6K
  • 20 Oct 2022
Topic Review
Cortes of Cádiz
The Cortes of Cádiz was a revival of the traditional cortes (Spanish parliament), which as an institution had not functioned for many years, but it met as a single body, rather than divided into estates as with previous ones. The General and Extraordinary Cortes that met in the port of Cádiz starting 24 September 1810 "claimed legitimacy as the sole representative of Spanish sovereignty", following the French invasion and occupation of Spain during the Napoleonic Wars and the abdication of the monarch Ferdinand VII and his father Charles IV. It met as one body, and its members represented the entire Spanish Empire, that is, not only Spain but also Spanish America and the Philippines. The Cortes of Cádiz was seen then, and by historians today, as a major step towards liberalism and democracy in the history of Spain and Spanish America. The liberal Cortes drafted and ratified the Spanish Constitution of 1812, which established a constitutional monarchy and eliminated many institutions that privileged some groups over others.
  • 1.6K
  • 25 Oct 2022
Topic Review
Impact of Artificial Intelligence on Dental Education
Most dental educators have limited knowledge and skills to assess AI applications, as they were not trained to do so. Also, AI technology has evolved exponentially. Factual reliability and opportunities with OpenAI Inc.’s ChatGPT are considered critical inflection points in the era of generative AI. Updating curricula at dental institutions is inevitable as advanced deep-learning approaches take over the clinical areas of dentistry and reshape diagnostics, treatment planning, management, and telemedicine screening. With advances in AI language models, communication with patients will change, and the foundations of dental education, including essay, thesis, or scientific paper writing, will need to adapt. However, there is a growing concern about its ethical and legal implications, and further consensus is needed for the safe and responsible implementation of AI in dental education.
  • 1.6K
  • 20 Feb 2023
Topic Review
Potential of Brown Algae
Brown algae have been part of the human diet for hundreds of years, however, in recent years, commercial and scientific interest in brown algae has increased due to the growing demand for healthier diet by the world population. Brown algae and its metabolites, such as carotenoids, polysaccharides, phlorotannins, and proteins, have been associated with multiple beneficial health effects for different diseases, such as cardiovascular diseases, one of the main causes of death in Europe.
  • 1.6K
  • 19 Feb 2021
Topic Review
Alpha-Ketoglutarate and 5-HMF
Clinical and pre-clinical studies of an anti-tumoral solution containing aKG, 5-HMF, N-acetyl-selenomethionine, and N-acetylmethionine for treating tumors showed, on one hand, good therapeutic efficacy during infusion therapy in prostate cancer patients by increasing the PSA doubling time; on the other hand, a reduction of tumoral mass was shown in lung cancer patients.
  • 1.6K
  • 19 Nov 2021
Topic Review
5G Wearable Devices
One potential way of enhancing capacity and data rates in the current and future mobile and wireless generations is the bandwidth. The data rates are directly proportional to the bandwidth. The higher bandwidth provides higher data rates. However, current frequency bands, i.e., 1.7 GHz GSM band, 1.8 GHz 4G/LTE band, 2.0 GHz 4G/LTE band, 2.1 LTE band, and 2.6 GHz band, provide limited bandwidth. Recently, high-frequency bands including 24 GHz (n258), 28 GHz (n257 and n261), 37 GHz (n260), and 39 GHz (n260) in addition to some future recommended bands, i.e., 47 and 60 GHz, have been considered for 5G applications.
  • 1.6K
  • 11 Jan 2022
Topic Review
Organosolv Lignin-Based Polyurethane
Polyurethanes (PUs) present an important class of polymers due to outstanding mechanical, chemical and physical properties. Thus, they find application in many industrial sectors in the form of flexible or rigid foams, coatings, adhesives, elastomers, thermoplasts or thermosets. Modern PU coating applications include self-healing coating films that can also be applied to rather rough surfaces, such as wood.
  • 1.6K
  • 22 Mar 2022
Topic Review
Air Emissions by Canada's Pulp and Paper Mills
The pulp and paper industry is a major contributor to water and air pollution globally. Pulp and paper processing is an intensive energy consuming process that produces multiple contaminants that pollute water, air, and affect ecological and human health. In Canada, the National Pollutant Release Inventory (NPRI) is used to assess the release of air pollutants into the atmosphere from industrial facilities (including pulp and paper mills) and provides a repository of annual emissions reported by individual facilities. 
  • 1.6K
  • 28 Apr 2022
Topic Review
Nanosecond Pulsed Electric Field Applications
Nanosecond Pulsed Electric Field (nsPEF) is an electrostimulation technique first developed in 1995; nsPEF requires the delivery of a series of pulses of high electric fields in the order of nanoseconds into biological tissues or cells. They primary effects in cells is the formation of membrane nanopores and the activation of ionic channels, leading to an incremental increase in cytoplasmic Ca2+ concentration, which triggers a signaling cascade producing a variety of effects: from apoptosis up to cell differentiation and proliferation. Further, nsPEF may affect organelles, making nsPEF a unique tool to manipulate and study cells. This technique is exploited in a broad spectrum of applications, such as: sterilization in the food industry, seed germination, anti-parasitic effects, wound healing, increased immune response, activation of neurons and myocites, cell proliferation, cellular phenotype manipulation, modulation of gene expression, and as a novel cancer treatment.
  • 1.6K
  • 16 Jun 2022
Topic Review
Go Strategy and Tactics
The game of Go has simple rules that can be learned very quickly but, as with chess and similar board games, complex strategies may be deployed by experienced players.
  • 1.6K
  • 27 Oct 2022
Topic Review
Social Learning Tools
Social learning tools are tools used for pedagogical and andragogical purposes that utilize social software and/or social media in order to facilitate learning through interactions between individuals and systems. The idea of setting up "social learning tools" is to make education more convenient and widespread. It also allows an interaction between users and/or the software which can bring a different aspect to learning. People can acquire knowledge by distance learning tools, for instance, Facebook, Twitter, Khan Academy and so on. Social learning tools may mediate in formal or informal learning environments to help create connections between learners, instructors and information. These connections form dynamic knowledge networks. Social learning tools are used in schools for teaching/learning and in businesses for training. Within a school environment, the use of social learning tools can affect not only the user (student) but his/her caretaker as well as his/her instructor. It brings a different approach to the traditional way of learning which affects the student and his/her support circle. Companies also use social learning tools. They used them to improve knowledge transfer within departments and across teams. Businesses use a variety of these tools to create a social learning environment. They are also used in company settings to help improve team work, problem solving, and performance in stressful situations. Social learning tools are used for people who are willing to share their good ideas/thoughts with someone else. The ideas can be related to either the academic studies or any other daily skills that we want to share with others. Social learning tools connect learning to our daily lives. It creates a learning environment more truthful to today's society. There are a couple of common elements that should be present in a social learning tool. Technology should be involved to allow physical and cognitive learning. There should be interactions between the people who use the tool and interactions with the software. Another element is trust. Users should trust the software and what other people have created.
  • 1.6K
  • 15 Nov 2022
Topic Review
The Role of ABC Transporters in the Skin
ABC transporters are expressed in skin cells to protect them against harmful xenobiotics. These transmembrane proteins have a number of additional functions that ensure skin homeostasis. 
  • 1.6K
  • 03 Jan 2023
Topic Review
New insights in Liver Regeneration
The physiological importance of the liver is demonstrated by its unique and essential ability to regenerate following extensive injuries affecting its function. By regenerating, the liver reacts to hepatic damage and thus enables homeostasis to be restored. The actors involved in the regenerative process are numerous and many of them are also pivotal players in both the immune and non-immune inflammatory process, that is observed in the early stages of hepatic regeneration. Balance of Th17/Treg is important in liver inflammatory process outcomes. 
  • 1.6K
  • 08 Feb 2023
Topic Review
Molecular Mechanism of Neuromyelitis Optica Spectrum Disorders
Neuromyelitis optica (NMO) is a rare autoimmune inflammatory disorder affecting the central nervous system (CNS), specifically the optic nerve and the spinal cord, with severe clinical manifestations, including optic neuritis (ON) and transverse myelitis. Initially, NMO was wrongly understood as a condition related to multiple sclerosis (MS), due to a few similar clinical and radiological features, until the discovery of the AQP4 antibody (NMO-IgG/AQP4-ab).NMO was expanded to NMO spectrum disorder (NMOSD) because of its varied clinical phenotypes. NMOSD is characterized by the activation of the complement cascade, granulocyte, eosinophil and lymphocyte infiltration, oligodendrocyte, and astrocyte injury, demyelination, and neuronal loss. The studies on gut microbiota and NMOSD explain the correlation between gut dysbiosis and NMOSD by signifying the abundance of pathogenic bacteria and reduction in commensal organisms, which cause abnormal metabolism and metabolic signals in the pathogenesis of autoimmune diseases such as NMOSD. 
  • 1.6K
  • 27 Apr 2023
Topic Review
‘Buildability’ in the Digital Age
Since the emergence of the concept of “buildability” in 1983, numerous studies have focused on improving project performance through buildability. Initially, the buildability discourse was based on narrow definitions and focused on aspects that could improve construction performance.
  • 1.6K
  • 23 Nov 2023
Topic Review
Quietism
Quietism in philosophy sees the role of philosophy as broadly therapeutic or remedial. Quietist philosophers believe that philosophy has no positive thesis to contribute, but rather that its value is in defusing confusions in the linguistic and conceptual frameworks of other subjects, including non-quietist philosophy. For quietists, advancing knowledge or settling debates (particularly those between realists and non-realists) is not the job of philosophy, rather philosophy should liberate the mind by diagnosing confusing concepts.
  • 1.6K
  • 17 Nov 2022
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