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Topic Review
Nutrients’ Role in Epigenetic Modifications
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by an aberrant immune response and persistent inflammation. Epigenetic changes are dynamic and susceptible to modification in response to environmental stimuli, which provides a feasible intervention to influence epigenetic homeostasis through an “epigenetic diet.” The term epigenetic diet was previously described by Daniel et al., referring to the consumption of certain foods, such as soy, grapes, vegetables, and green tea, which exert mechanisms against aging and cancer. 
  • 1.8K
  • 28 Feb 2023
Topic Review
Carbon Nanotubes
Carbon nanotubes are a quasi-one-dimensional nanomaterial having excellent compatibility with cementitious material. Recently several research carried out utilising different types of Carbon nanotubes (Single wall carbon nanotube, multiwall carbon nanotube, -COOH and -OH functionalised carbon nanotube etc.) to investigate its influences in terms of flowability, microstructure, mechanical, and durability properties. CNT is chemically inert material but addition of small doses of CNTs can significantly improve the mechanical and microstructural properties of concrete/cementitious composites. CNT act as nucleating agents and promote the higher growth of C-S-H. However, improvement of mechanical, microstructural  and durability properties depends on CNTs concentration, physical properties and type of CNTs. 
  • 1.8K
  • 27 Oct 2020
Topic Review
ElectroKinetic Remediation
The ElectroKinetic Remediation Technology (EKRT) is an electrochemical approach that is applied for the remediation of contaminated soils. Electrochemical approaches have gained prominence thanks to the many possible applications and their proven effectiveness. This is particularly evident in the case of inorganic/ionic contaminants, which are not subject to natural attenuation (biological degradation) and are difficult to treat adequately with conventional methods.
  • 1.8K
  • 01 Feb 2021
Topic Review
Tumor-Associated Macrophages
Resident macrophage populations within tumors are termed tumor-associated macrophages (TAMs) and can comprise up to half of the tumor mass. In established solid malignancies, the anti-tumor functions of TAMs such as phagocytosis and cytotoxic activity are suppressed, and TAMs are subverted to facilitate tumor growth.
  • 1.8K
  • 29 Mar 2022
Topic Review
Fibrous Concretes Produced by Using Wollastonite
Production of cement and aggregate used in cement-based composites causes many environmental and energy problems. Decreasing the usage of cement and aggregate is a crucial and currently relevant challenge to provide sustainability. Inert materials can also be used instead of cement and aggregates, similar to pozzolanic materials, and they have positive effects on cement-based composites. One of the inert materials used in cement-based composites is wollastonite (calcium metasilicate-CaSiO3), which has been investigated and attracted attention of many researchers.
  • 1.8K
  • 19 Oct 2022
Topic Review
Microchromosome Organization in Birds
Interchromosomal rearrangements involving microchromosomes are rare events in birds. To date, they have been found mostly in Neognathae and Neoaves (e.g., Psittaciformes, Falconiformes, and Cuculiformes), although only a few orders have been analyzed. Hence, cytogenomic studies focusing on microchromosomes in species belonging to different bird orders are essential to shed more light on the avian chromosome and karyotype evolution. Relevant hypothetical Neognathae, Neoaves and other ancestral karyotypes can be reconstructed to trace these rearrangements. In a more recent study, a comparative chromosome mapping for chicken microchromosomes 10 to 28 was performed using interspecies BAC-based FISH hybridization in five species, representing four Neoaves orders (Caprimulgiformes, Piciformes, Suliformes, and Trogoniformes). These results suggest that the ancestral microchromosomal syntenies are conserved in Pteroglossus inscriptus (Piciformes), Ramphastos tucanus tucanus (Piciformes), and Trogon surrucura surrucura (Trogoniformes). On the other hand, chromosome reorganization in Phalacrocorax brasilianus (Suliformes) and Hydropsalis torquata (Caprimulgiformes) included fusions involving both macro- and microchromosomes. Fissions in macrochromosomes were observed in P. brasilianus and H. torquata. No interchromosomal rearrangement involving microchromosomes were found to be shared between avian orders where rearrangements were detected. These findings suggest that convergent evolution involving microchromosomal change is a rare event in birds and may be appropriate in cytotaxonomic inferences in orders where these rearrangements occurred.
  • 1.8K
  • 21 Oct 2022
Topic Review
Polymer-Matrix Composites - Environmental Fatigue, Creep, Long-Term Durability
Polymer-matrix composites are widely used in engineering applications. Yet, environmental factors impact their macroscale fatigue and creep performances significantly, owing to several mechanisms acting at the microstructure level. Seawater, due to a combination of high salinity and pressures, low temperature and biotic media present, also contributes to the acceleration of fatigue and creep damage. Similarly, other liquid corrosive agents penetrate into cracks induced by cyclic loading and cause dissolution of the resin and breakage of interfacial bonds. UV radiation either increases the crosslinking density or scissions chains, embrittling the surface layer of a given matrix. Temperature cycles close to the glass transition damage the fibre–matrix interface, promoting microcracking and hindering fatigue and creep performance. The microbial and enzymatic degradation of biopolymers is also studied, with the former responsible for metabolising specific matrices and changing their microstructure and/or chemical composition. 
  • 1.8K
  • 07 Jul 2023
Topic Review
Successful and Emerging Cyberbullying Prevention Programs
The advent of the internet has channeled more online-related tasks into our lives and they have become a pre-requisite. One of the concerns with high internet usage is the multiplication of cyber-associated risky behaviors such as cyber aggression and/or cyberbullying. Cyberbullying is an emerging issue that needs immediate attention from many stakeholders.
  • 1.8K
  • 27 Sep 2023
Topic Review
Arch-Dams’ Building Risk Reduction
The are thousands of large dams over the globe. The importance of dams is rapidly increasing due to the impact of climate change on increasing hydrological process variability and on water planning and management need. This study tackles a review for the concrete arch-dams’ design process, from a dual sustainability/safety management approach. On one hand, Sustainability is evaluated through a design optimization for dams´ stability and deformation analysis. On the other hand, safety is directly related to the reduction and consequences of failure risk. For that, several scenarios about stability and deformation, identifying desirable and undesirable actions, were estimated. More than 100 specific parameters regarding dam-reservoir-foundation-sediments system and their interactions have been collected. Also, a summary of mathematical modelling was made, and more than 100 references were summarized. The following consecutive steps, required to design engineering (why act), maintenance (when to act) and operations activities (how to act), were evaluated: individuation of hazards, definition of failure potential and estimation of consequences (harm to people, assets and environment). Results show that the area to model the dam–foundation interaction is around 3.0 Hd2, the system-damping ratio and vibration period is 8.5% and 0.39 s. Also, maximum elastic and elasto-plastic displacements are ~0.10–0.20 m. The failure probability for stability is 34%, whereas for deformation it is 29%
  • 1.8K
  • 30 Oct 2020
Topic Review
Non-Fullerene Acceptors of IDIC/ITIC Families
IDIC/ITIC families of non-fullerene acceptors has boosted the photovoltaic performances of bulk-heterojunction organic solar cells. The fine tuning of the photophysical, morphological and processability properties with the aim of reaching higher and higher photocurrent efficiencies has prompted uninterrupted worldwide research on these peculiar families of organic compounds.
  • 1.8K
  • 17 Nov 2020
Topic Review
Candida Albicans in Psoriasis
Psoriasis is a T cell-mediated skin disease resulting from epithelial and immunological cells’ interactions, which affects around 2% of the population worldwide. Its onset is influenced by genetic and environmental factors, particularly infections among which Streptococcus pyogenes is the best characterized. However, the commensal fungus Candida albicans has been also associated to triggering psoriasis. Here we discuss what it is known about the link betweeen Candida and psoriasis pathogenesis.
  • 1.8K
  • 22 Sep 2021
Topic Review
Glycosides
Glycosides have been identified in almost every type of plant tissue including leaves, roots, stems, and reproductive organs (i.e., flowering and fruiting bodies). The direct role of glycosides in plants is still uncertain, but it is hypothesized that glycosides were a part of the “chemodiversity” necessary for plants to survive. The addition of sugar moieties onto hydrophobic aglycones changes the overall polarity and water solubility of the aglycone. The increased polarity of the glycoside allows for detoxification, storage, and transport within the plant.
  • 1.8K
  • 11 May 2021
Topic Review
Particle-Bound Mercury Characterization
Particulate Bound Hg (PBM) consists of all airborne particulate containing Hg, including both stable condensed and gaseous forms adsorbed on atmospheric particulate matter (PM); it is operationally sampled and quantified by pulling air through a glass fiber or a quartz filter. PBM usually includes all those particles with a diameter <2.5 μm, even if its characterization depends on the pore size of the filter used for its collection. The accurate dimensional characterization is then essential to estimate the dry deposition of PBM, as well as any other particulate pollutant; the particles diameters directly influence gravitational sedimentation and the PBM residence time in the atmosphere. In addition, PBM chemical speciation, as well as for the other Hg forms, is fundamental to understand PBM bioavailability and therefore the effects on human .
  • 1.8K
  • 05 Jul 2021
Topic Review
Multilevel Single Use Plastics Governance
Unsustainable production and consumption patterns of single-use plastics (SUP) are causing worldwide negative environmental and socioeconomic impacts on land-based and marine ecosystems. As a transboundary problem, global governance of plastics includes international agreements and voluntary multi-stakeholder platforms, focused mainly on oceans and marine life. Nevertheless, adaptation and mitigation strategies are required in local territories. National governments and municipalities have approved uneven local policies with inconsistent standards. This entry briefly discusses plastic pollution, global and regional responses, particular emphasis in Latin America, and the regional framework of the Pacific Alliance. 
  • 1.8K
  • 07 Jul 2021
Topic Review
Microbial Pyrrolnitrin
Pyrrolnitrin (PRN) is a microbial pyrrole halometabolite of immense antimicrobial significance for agricultural, pharmaceutical and industrial implications. The compound and its derivatives have been isolated from rhizospheric fluorescent or non-fluorescent pseudomonads, Serratia and Burkholderia. They are known to confer biological control against a wide range of phytopathogenic fungi, and thus offer strong plant protection prospects against soil and seed-borne phytopathogenic diseases. Although chemical synthesis of PRN has been obtained using different steps, microbial production is still the most useful option for producing this metabolite. In many of the plant-associated isolates of Serratia and Burkholderia, production of PRN is dependent on the quorum-sensing regulation that usually involves N-acylhomoserine lactone (AHL) autoinducer signals. When applied on the organisms as antimicrobial agent, the molecule impedes synthesis of key biomolecules (DNA, RNA and protein), uncouples with oxidative phosphorylation, inhibits mitotic division and hampers several biological mechanisms. 
  • 1.8K
  • 01 Sep 2021
Topic Review
Oxidative Quality of Dairy Powders
Lipid oxidation (LO) is a primary cause of quality deterioration in fat-containing dairy powders and is often used as an estimation of a products shelf-life and consumer acceptability. The LO process produces numerous volatile organic compounds (VOC) including aldehydes, ketones and alcohols, which are known to contribute to the development of off-flavours in dairy powders. The main factors influencing the oxidative state of dairy powders and the various analytical techniques used to detect VOC as indicators of LO in dairy powders are outlined.
  • 1.8K
  • 19 Oct 2021
Topic Review
Travel sentiment after COVID-19
Tourism and hospitality actors face an unprecedented challenge in reigniting these industries through digital communication. All past knowledge regarding tourist behavior and preferences has been rendered less relevant since the outbreak of the COVID-19 pandemic. These changes result in enforced changes that need to be acknowledged. Several reports have pointed to the existence of a travel sentiment. This travel sentiment integrates the travel intentions and concerns, and trip planning which can be actionable by digital communication.
  • 1.8K
  • 19 Nov 2021
Topic Review
Algae and Fungi: use in Pre-Hispanic Mexico
The use of microorganisms in Mexico began before the Spanish conquest. Grains and fruit were fermented for thousands of years around the world, and Mexico was no exception. Many beverages are still prepared nowadays using an assortment of different microorganisms. These beverages use several yeasts, including Saccharomyces and non-Saccharomyces species. Although not conclusive, it has been suggested (and strong evidence points towards it) that pre-Hispanic cultures not only fermented beverages, but also distilled them.
  • 1.8K
  • 13 Dec 2021
Topic Review
Metal-Catalyzed Synthesis of the OSe Compounds
Organoselenium (OSe) compounds have recently gained considerable interest as a potential class of organic motifs due to their outstanding applications in synthetic organic and medicinal chemistry and their possible properties in materials science. These are attributed to the exceptional properties of the selenium (Se) element.
  • 1.8K
  • 02 Jun 2022
Topic Review
Bacterial Lipopolysaccharides
Bacterial lipopolysaccharides (LPS), also referred to as endotoxins, are major outer surface membrane components present on almost all Gram-negative bacteria and are major determinants of sepsis-related clinical complications including septic shock. LPS acts as a strong stimulator of innate or natural immunity in a wide variety of eukaryotic species ranging from insects to humans including specific effects on the adaptive immune system.
  • 1.8K
  • 25 Aug 2022
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