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Topic Review
PEDOT:PSS/Nonionic WPU
Poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) has the merits of high electrical conductivity and solution processability, and can be dispersed in water. To improve the stretchability of PEDOT:PSS-based transparent electrode films, the intrinsically conducting polymer PEDOT:PSS was blended with highly stretchable nonionic waterborne polyurethane (WPU) and coated on a thermoplastic polyurethane (TPU) film. Nonionic WPU has good compatibility with PEDOT:PSS, without affecting the acidity. 
  • 1.9K
  • 16 Mar 2022
Topic Review
Design and Development of Novel Nutraceuticals
The global prevalence of nutraceuticals is reflected in the increasing number of commercially available nutraceuticals and their wide range of applications. Therefore, a unique opportunity emerges for their further exploration using innovative, reliable, accurate, low cost, and high hit rate methods to design and develop next generation nutraceuticals. Towards this direction, computational techniques constitute an influential trend for academic and industrial research, providing not only the chemical tools necessary for further mechanism characterization but also the starting point for the development of novel nutraceuticals. 
  • 1.9K
  • 27 May 2022
Topic Review
Green Innovation and Corporate Social Responsibility
Indonesia’s government policy recommends that medium and large companies carry out corporate social responsibility programs. These programs provide sustainability for the company because they can involve community social relations, economic growth, and increasing environmental awareness. Corporate social responsibility can increase green innovation in companies with the stability of environmentally friendly materials, emission reductions for the surrounding community, and saving energy use. Corporate social responsibility has a positive effect on firm performance because the company has maintained the continuity of the process. After all, it has a harmonious relationship with the community. Furthermore, green innovation positively affects firm performance because the company can reduce energy use and utilize environmentally friendly resources. Therefore, green innovation can mediate the influence of corporate social responsibility and firm performance. 
  • 1.9K
  • 31 May 2022
Topic Review
Molecular Markers
Fungi are amongst the most abundant and diverse organisms. Despite being widely known for their adverse role in food spoilage or as pathogens for humans, animals, or plants, they also present several beneficial effects. Fungi contribute to human well-being due to their role as decomposers, degrading decay matter into smaller molecules which can be easily used by other ecosystem members. These organisms can produce medicinal compounds or modulate protective immune responses in human intestine. Fungi intervene in diverse food processes or act as a food supply. Due to fungal diversity, the unequivocal identification of these organisms is crucial to increasing their practical applications and decreasing their adverse effects.
  • 1.9K
  • 02 Aug 2022
Topic Review
Biological Effects of Radiotherapy in Cancer Cells
Radiotherapy remains an effective conventional method of treatment for patients with cancer. However, the clinical efficacy of radiotherapy is compromised by the development of radioresistance of the tumor cells during the treatment. The main goal of radiotherapy is to destroy or slow tumor growth by using high-energy radiation, such as X-rays, gamma (γ) rays, electrons, protons, neutrons, and carbon ions. The efficacy of killing is influenced by a number of factors, including the type of radiation, the total dose, the fractionation rate, and the targeted organs.
  • 1.9K
  • 24 Oct 2022
Topic Review
Former Constellation
Former constellations are old historical Western constellations that for various reasons are no longer widely recognised or are not officially recognised by the International Astronomical Union (IAU). Prior to 1930, many of these defunct constellations were traditional in one or more countries or cultures. Some only lasted decades but others were referred to over many centuries. All are now recognised only for having classical or historical value. Many former constellations had complex Latinised names after objects, people, or mythological or zoological creatures. Others with unwieldy names were shortened for convenience. For example, Scutum Sobiescianum was reduced to Scutum, Mons Mensae to Mensa, and Apparatus Sculptoris to Sculptor. Some of the Northern Sky's former constellations were placed in the less populated regions between the traditional brighter constellations just to fill gaps. In the Southern Sky, new constellations were often created from about the 15th century by voyagers who began journeying south of the Equator. European countries like England, France, the Netherlands, German or Italian states, etc., often supported and popularised their own constellation outlines. In some cases, different constellations occupied overlapping areas and included the same stars. These former constellations are often found in older books, star charts, or star catalogues. The 88 modern constellation names and boundaries were standardised by Eugene Delporte for the IAU in 1930, under an international agreement, removing any possible astronomical ambiguities between astronomers from different countries. Nearly all former or defunct constellations differ in their designated boundaries in as much as they have outlines that do not follow the exact lines of right ascension and declination.
  • 1.9K
  • 05 Nov 2022
Topic Review
Regeneration in Reptiles
The ability to repair injuries among reptiles, i.e., ectothermic amniotes, is similar to that of mammals with some noteworthy exceptions. While large wounds in turtles and crocodilians are repaired through scarring, the reparative capacity involving the tail derives from a combined process of wound healing and somatic growth, the latter being continuous in reptiles. When the tail is injured in juvenile crocodilians, turtles and tortoises as well as the tuatara (Rhynchocephalia: Sphenodon punctatus, Gray 1842), the wound is repaired in these reptiles and some muscle and connective tissue and large amounts of cartilage are regenerated during normal growth. This process, here indicated as “regengrow”, can take years to produce tails with similar lengths of the originals and results in only apparently regenerated replacements. 
  • 1.9K
  • 18 Sep 2021
Topic Review
Transcriptionally Active Chromatin Structure
Chromatin structure can either positively or negatively regulates transcription and plays an essential role in eukaryotic gene expression and cell identity. 
  • 1.9K
  • 13 May 2021
Topic Review
Agriculture and Pollinator Biodiversity
Pollinator biodiversity is greatly affected by industrialized agriculture practices. Agroecological alternatives for food production must be implemented. 
  • 1.9K
  • 22 Jul 2021
Topic Review
Seed Geometry in the Vitaceae
The Vitaceae Juss., in the basal lineages of Rosids, contains sixteen genera and 950 species, mainly of tropical lianas. The family has been divided in five tribes: Ampelopsideae, Cisseae, Cayratieae, Parthenocisseae and Viteae. Seed shape is variable in this family and is described based on the comparison of bi-dimensional seed images with geometric models. Ten morphological types are described in the Vitaceae. Seven of them are general and three specific. Among the general types, three are shared with the Arecaceae and correspond to geometric figures well described (lenses, superellipses and elongated waterdrops). Four additional groups include waterdrops, normal or rounded, heart curves, normal or rounded, elongated heart curves and other elongated curves, respectively. Finally, the three specific types correspond to heart curves of the Cayratia and Pseudocayratia types, heart curves of the Squared Heart Curve (SqHC) type of Ampelocissus and Ampelopsis, and Elongated Superellipse-Heart Curves (ESHCs), frequent in Tetrastigma species and observed also in Cissus species and R. rhomboidea. All these groups are defined by geometric models obtained by the representation of algebraic equations. Modifications in the equations result in models adjusting to the shape of seeds for each species.
  • 1.9K
  • 13 Sep 2021
Topic Review
Early Childhood Education in China
Early childhood education (ECE) in China has become complex and multi-dimensional. Chinese parents/caregivers are actively involved in ECE.
  • 1.9K
  • 13 Oct 2021
Topic Review
Keratin 6, 16 and 17
Located at the skin surface, keratinocytes (KCs) are constantly exposed to external stimuli and are the first responders to invading pathogens and injury. Upon skin injury, activated KCs secrete an array of alarmin molecules, providing a rapid and specific innate immune response against danger signals. However, dysregulation of the innate immune response of KCs may lead to uncontrolled inflammation and psoriasis pathogenesis. Keratins (KRT) are the major structural intermediate filament proteins in KCs and are expressed in a highly specific pattern at different differentiation stages of KCs. While KRT14-KRT5 is restricted to basal proliferative KCs, and KRT10-KRT1 is restricted to suprabasal differentiated KCs in normal skin epidermis, the wound proximal KCs downregulate KRT10-K1 and upregulate KRT16/KRT17-KRT6 upon skin injury. Recent studies have recognized KRT6/16/17 as key early barrier alarmins and upregulation of these keratins alters proliferation, cell adhesion, migration and inflammatory features of KCs, contributing to hyperproliferation and innate immune activation of KCs in response to an epidermal barrier breach, followed by the autoimmune activation of T cells that drives psoriasis. 
  • 1.9K
  • 21 Mar 2022
Topic Review
End Effectors in Agricultural Robotic Harvesting Systems
An end effector is a peripheral device attached to a robot’s wrist, enabling interaction during a task. For harvesting robots, the end effector is considered the contact point between the robot and the product to be harvested. Robotic systems have been designed to cover labor shortage, to increase the speed of harvesting, and to improve the efficiency of harvesting.
  • 1.9K
  • 30 Aug 2022
Topic Review
Pig and Wild-Boar Distinguishing
The pig, one of the most important livestock species, is a meaningful source of global meat production. It is necessary to prove whether a food product that a discerning customer selects in a store is actually made from pork or venison, or does not contain it at all. The problem of food authenticity is widespread worldwide, and cases of meat adulteration have accelerated the development of food and the identification methods of feed species. It is worth noting that several different molecular biology techniques can identify a porcine component.
  • 1.9K
  • 31 Oct 2022
Topic Review
Oral Melanosis
Oral melanosis is a benign pigmented lesion arising in the oral cavity. Oral pigmentation is asymptomatic and does not usually cause any alteration to the texture or thickness of the affected area. The colour can be uniform or speckled and can appear solitary or as multiple lesions. Depending on the site, depth, and quantity of pigment, the appearance can vary considerably. Oral pigmentation is found in the following places: Oral pigmentation affects about 3% of the population and is most likely seen in those with dark skin; however people with light skin have, on average, 30 local pigmented areas and in some circumstances will present intra-orally. They are more often found in females than males and the typical age at presentation is 40 years although they can appear at any age. Diagnosis of oral pigmentation is by a complete history taken by the clinican followed by a thorough clinical examination. Management of such lesions is typically by close clinical monitoring, photographs and measuring tools. A biopsy may be indicated where the following features are present: large or new-pigmented lesions and those with a papular appearance or irregular colouration.
  • 1.9K
  • 11 Nov 2022
Topic Review
Chitosan-Based Electrochemical Sensors for Pharmaceuticals Detection
This research explores advances in the detection and quantification of pharmaceutical substances, with a focus on the development of high-performance electrochemical sensors, particularly those based on chitosan, to address the need for sensitive and selective detection techniques in various applications.
  • 1.9K
  • 07 Sep 2023
Topic Review
Renewable Energy Hybrid Systems
Renewable energies are those sources of energy that can be obtained naturally without depleting the planet’s resources. Hybrid renewable energy systems are those that combine two or more renewable energy sources to generate electricity.
  • 1.9K
  • 20 Oct 2023
Topic Review
Health and Oral Health Coaching
Health-related behavior based on diet is an important determinant of oral health in independent elderly. Aging impairs senses, mastication, oral status, and function, causing nutritional needs and diet insufficiencies that contribute to a vicious circle of impairment. But the present needs of independent older adults suggest that health research and oral health care should shift from disease management and therapy to integral customized and personal treatment plans, including lifestyle, psychological, nutritional, and oral health coaching approaches. In this paper health coaching approaches in medical and dental settings are valued as to their effectiveness for older adults. Furthermore, coaching approaches for seniors are discussed and coaching models for better senior patient-dentist cooperation on the diet issue are suggested. Diet and oral health coaching is proven to be a modern senior patient-centered approach that needs to be incorporated at all relevant settings. It should aim to empower older adults in co-management of their oral diseases or bad diet habits affecting their oral health. This can be carried out through an incorporated educational plan for dentists either at the postgraduate or professional level since advantages seem to enhance the quality of life of the independent elderly.
  • 1.9K
  • 31 Jan 2022
Topic Review
Histone Monoubiquitination in Chromatin Remodelling
Chromatin remodelling is a major mechanism by which cells control fundamental processes including gene expression, the DNA damage response (DDR) and ensuring the genomic plasticity required by stem cells to enable differentiation. The post-translational modification of histone H2B resulting in addition of a single ubiquitin, in humans at lysine 120 (K120; H2Bub1) and in yeast at K123, has key roles in transcriptional elongation associated with the RNA polymerase II-associated factor 1 complex (PAF1C) and in the DDR. H2Bub1 itself has been described as having tumour suppressive roles and a number of cancer-related proteins and/or complexes are recognised as part of the H2Bub1 interactome. These include the RING finger E3 ubiquitin ligases RNF20, RNF40 and BRCA1, the guardian of the genome p53, the PAF1C member CDC73, subunits of the switch/sucrose non-fermenting (SWI/SNF) chromatin remodelling complex and histone methyltransferase complexes DOT1L and COMPASS, as well as multiple deubiquitinases including USP22 and USP44. While globally depleted in many primary human malignancies, including breast, lung and colorectal cancer, H2Bub1 is selectively enriched at the coding region of certain highly expressed genes, including at p53 target genes in response to DNA damage, functioning to exercise transcriptional control of these loci.
  • 1.9K
  • 16 Dec 2020
Topic Review
Criminal Poisonings
Criminal poisonings are among the least frequently detected crimes in the world. Lack of suspicion of this type of event by police officers and prosecutors, clinical symptoms imitating many somatic diseases and technical difficulties in diagnostics, as well as high research costs make the actual frequency of these events difficult to estimate. The substance used for criminal poisoning is often characterized by: lack of taste, color and smell, delayed action, easy availability and difficulty to detect.
  • 1.9K
  • 24 Aug 2022
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