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Topic Review
Biological Activities of Thiophenes
Thiophenes represent a small family of natural metabolites featured by one to five thiophene rings. Numerous plant species belonging to the family Asteraceae commonly produce thiophenes. These metabolites possessed remarkable bioactivities, including antimicrobial, antiviral, anti-inflammatory, larvicidal, antioxidant, insecticidal, cytotoxic, and nematicidal properties.
  • 2.7K
  • 16 Jan 2024
Topic Review
Maned Wolf
The Maned Wolf (Chrysocyon brachyurus) is a distinctive canid species native to South America, particularly inhabiting grasslands and savannas. Despite its name, the Maned Wolf is not closely related to wolves but represents a unique evolutionary lineage within the canid family. Recognizable for its long, slender legs, reddish-brown fur, and distinctive black mane, this solitary omnivore plays a crucial role in its ecosystem as both a predator and a seed disperser.
  • 2.7K
  • 28 Feb 2024
Topic Review
Resources Cycle
Resources cycle means volatility in the resources sector over a period of time based on metrics such as value or production volume. Resource cycles present considerable heterogeneity with differing time lines but generally run from a low point (production, demand or value) through a period of increase, before returning to a comparable low point. Since the turn of the century this concept has driven discourse and research into housing markets, investment opportunities and socioeconomic change in resource towns of a country as the impacts of mining driven change become increasingly pronounced.
  • 2.7K
  • 23 Aug 2021
Topic Review
Fossil Fuels Lobby
"Fossil fuels lobby" is a term used to label the paid representatives of large fossil fuel (oil, gas, coal) and electric utilities corporations who attempt to influence governmental policy. So-called Big Oil companies such as ExxonMobil, Royal Dutch Shell, BP, Total S.A., Chevron Corporation, and ConocoPhillips are amongst the largest corporations associated with the fossil fuels lobby. General Electric, Southern Company, First Energy, and the Edison Electric Institute are also among the most influential electric utilities corporations. By sector, "Energy/Nat Resource" comes fifth, behind "Misc Business", "Finance/Insur/RealEst", Health and "Communic/Electronics".
  • 2.7K
  • 27 Oct 2022
Topic Review
Biological Barriers to Oral Drug Delivery Systems
The oral route is the most preferred route for systemic and local drug delivery. However, the oral drug delivery system faces the harsh physiological and physicochemical environment of the gastrointestinal tract, which limits the bioavailability and targeted design of oral drug delivery system.
  • 2.7K
  • 08 Feb 2023
Topic Review
Basic Principles and Operation Modes of AFM
Atomic force microscopy (AFM) is a method that provides the nanometer-resolution three-dimensional imaging of living cells in their native state in their natural physiological environment. AFM is a versatile tool for the high-resolution three-dimensional imaging, nanomechanical characterization and measurement of inter- and intramolecular forces in living and non-living structures. The AFM probe, which has a nm-sized tip, measures the interatomic forces between the sample surface and the tip apex. Sample preparation for AFM measurements is simple, and there is no need for the freezing, metal coating or staining of the sample. As a result, there is little-to-no damage to the sample, and the functions of biological systems can be preserved. AFM works in both air and liquids; so, physiological buffers and growth media can be used to study living cells. The high resolution of AFM allows the imaging of atoms on hard surfaces and molecules on soft biological samples.
  • 2.7K
  • 12 Jun 2023
Topic Review
Nutritional Composition of Ripe Hass Avocado Pulp
Avocados (Persea americana) are a unique fruit that can provide health benefits when included in a healthy diet. As health care moves towards precision health and targeted therapies or preventative medicine, it is critical to understand foods and their dietary components. The nutritional composition and plant physiology of the Hass avocado is strikingly different from other fruits. The ripe fruit is rich in oleic acid, fiber, micronutrients (e.g., folate, vitamin K, copper, pantothenic acid), and various important phytochemicals, such as lutein, zeaxanthin, and phytosterols.
  • 2.7K
  • 17 Jul 2023
Topic Review
Food Waste Valorisation Techniques
Food waste valorisation techniques aim to convert food waste into value-added products that can be integrated into various stages of the food supply chain. Some sustainable techniques for food waste valorisation include composting, anaerobic digestion, bioconversion, and upcycling.
  • 2.7K
  • 14 Aug 2023
Topic Review
Humidification and Dehumidification Desalination
Humidification–dehumidification desalination (HDH) is described as a novel volume reduction method that employs a carrier gas for the thermal desalination of water. Currently used for small scale desalination, the advantages provided by the HDH method are too great to be ignored. The benefits of the process include the use of low-grade energy and simple design and construction.
  • 2.7K
  • 14 Jan 2022
Topic Review
Imaging Techniques in Adult Acquired Flatfoot Deformity
Adult acquired flatfoot deformity (AAFD) is a disorder caused by repetitive overloading, which leads to progressive posterior tibialis tendon (PTT) insufficiency. It mainly affects middle-aged women and occurs with foot pain, malalignment, and loss of function. After clinical examination, imaging plays a key role in the diagnosis and management of this pathology. Imaging allows confirmation of the diagnosis, monitoring of the disorder, outcome assessment and complication identification. 
  • 2.7K
  • 28 Jan 2023
Topic Review
Volatile Organic Compounds
Volatile organic compounds (VOCs) are promising alternatives to synthetic pesticides in pest and disease management. VOCs are gaining interest due to the various advantages of their application, such as the reduction in residuals in the environment and their ease of application in different agricultural systems. 
  • 2.7K
  • 18 Apr 2023
Topic Review
Punica Granatum Vrs COVID-19
Punica granatum is historically known worldwide as a versatile medicinal fruit. 2 major varieties are presented (i) indo Ayurvedic type (Punica Ayurvedica ? ) that is small, harsh and yields no juice and (ii) the juice variety which is commercialised. Indo-Iranian joint effort presents a tome of textual data pertaining to the medicinal aspects of Punica. Ayurvedic texts and Occidental research modelled papers in tabulated form chronologically succinctly bringing out the evidence based historiography & medico-cultural heritage. On such platform a range of formulations; fruit-to-finished product are presented for the 1st time machine makeable and very specifically also by hand, at home. Poly pathology spectrum; versatile therapeutic range; medico-legal; lyophilisation; sterilisation; etc. aspects are also indicated. Includes Tablets; Suspensions for General to Geriatric case types. Ground breaking. Frank.
  • 2.7K
  • 27 Oct 2020
Topic Review
Relation between Energy Efficiency and Industry 4.0
The industrial sector is the most energy-consuming sector before the transport and residential sectors. It accounts for about 31% of the overall energy consumption. For this reason, manufacturers are placing increasing emphasis on energy efficiency through improvements in energy management, energy devices, and insulation. Energy efficiency improvement is the application of engineering principles and best practices to control the energy consumption of a facility. It is a continuous process that requires the full involvement of all stakeholders (managers, engineers, workers, etc.) to identify, formulate proposals, and implement energy efficiency technologies and practices to reduce energy consumption. Many technologies and practices are currently available and in development that could save energy if adopted by industry, classified into two main categories: energy management technologies and energy devices. In addition, various tools and methods are used, such as energy monitoring tools, process modeling and integration, optimization and simulation tools, energy analysis and decision support tools, etc. One of the recent innovations is the introduction of Industry 4.0 in manufacturing, in other words, the transition to the new industrial era.
  • 2.7K
  • 15 Jun 2022
Topic Review
YAP/TAZ Activation in Head and Neck Cancer
The Hippo signaling pathway, originally discovered as a mechanism regulating tissue growth and organ size, transduces intracellular and extracellular signals to regulate the transcriptional co-activators YAP and TAZ. Alterations in the Hippo pathway resulting in persistent YAP and TAZ activation have emerged as major oncogenic drivers. The researchers' analysis of the human Head and neck squamous cell carcinoma (HNSCC) oncogenome revealed multiple genomic alterations impairing Hippo signaling and activating YAP and TAZ, which in turn contribute to HNSCC development. This includes mutations and deletions of the FAT1 gene (29%) and amplification of the WWTR1 (encoding TAZ, 14%) and YAP1 genes (8%), together representing one of the most genetically altered signaling mechanisms in this malignancy. 
  • 2.7K
  • 11 May 2022
Topic Review
Consent Decree
A consent decree is an agreement or settlement that resolves a dispute between two parties without admission of guilt (in a criminal case) or liability (in a civil case), and most often refers to such a type of settlement in the United States . The plaintiff and the defendant ask the court to enter into their agreement, and the court maintains supervision over the implementation of the decree in monetary exchanges or restructured interactions between parties. It is similar to and sometimes referred to as an antitrust decree, stipulated judgment, settlement agreements, or consent judgment. Consent decrees are frequently used by federal courts to ensure that businesses and industries adhere to regulatory laws in areas such as antitrust law, employment discrimination, and environmental regulation.
  • 2.7K
  • 07 Nov 2022
Topic Review
Classification of the Luting Materials
A dental luting material aids in the retention and stability of indirect restorations on the prepared tooth structure. The luting materials can generally be classified by their chemical compositions, bonding mechanisms or clinical indications.
  • 2.7K
  • 15 Nov 2022
Topic Review
Intercession of the Theotokos
The Intercession of the Theotokos, or the Protection of Our Most Holy Lady Theotokos and Ever-Virgin Mary, is a feast of the Mother of God celebrated in the Eastern Orthodox and Byzantine Catholic Churches. The feast celebrates the protection afforded the faithful through the intercessions of the Theotokos (lit. Mother of God, the Eastern title of the Virgin Mary). In the Slavic Orthodox Churches it is celebrated as the most important solemnity besides the Twelve Great Feasts and Pascha. The feast is commemorated in Eastern Orthodoxy as a whole, but by no means as fervently as it is in Russia , Belarus and Ukraine . It is not a part of the ritual traditions of, and therefore is not celebrated by, the Oriental Orthodox Churches or some jurisdictions that allow Western Rite Orthodoxy. Yet the feast is perfectly consistent with the theology of these sister churches. It is celebrated on October 14 (OS October 1). The Western Rite Communities of the Russian Orthodox Church Outside of Russia (ROCOR) do celebrate this feast on their calendar.
  • 2.7K
  • 24 Nov 2022
Topic Review
Characteristics and Hazards of Lead–Zinc Tailings
Lead–zinc tailings are the typical solid wastes in mines with high yield and low utilization rates in some countries. They are mainly stockpiled in tailings reservoirs, occupying massive land resources and threatening the health of the environment. 
  • 2.7K
  • 17 Jan 2023
Topic Review
Pyrazole Biomolecules as Cancer and Inflammation Therapeutics
The pyrazole moiety is a heterocyclic ring system (five membered) with 3 C and 2 N in adjacent sites. Pyrazole compounds have an extensive past of applications, being used as herbicides, agrochemicals, and as active pharmaceutical agents. Pyrazole derivatives exhibit anti-inflammatory properties and have been shown to target several cancer cell lines, such as COX (I/II).
  • 2.7K
  • 10 Feb 2023
Topic Review
Bluetooth Low Energy Mesh Networks
Bluetooth Low Energy (BLE) is an increasingly prevalent Wireless Ad-Hoc Network (WAHN) technology for battery-powered Internet of Things (IoT) devices [1]. The BLE standard was introduced by the Bluetooth Special Interest Group (SIG) in Bluetooth version 4.0, and subsequently enhanced in versions 4.2 and 5. Initially, BLE 4.x adopted the legacy Bluetooth Personal Area Network (PAN) model for multi-hop communications and the interconnection of networks. BLE 5 intends to address these inadequacies via the implementation of pure mesh topology to provide enhanced network coverage, inter-network connectivity, and improved security [2].
  • 2.7K
  • 28 Oct 2020
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