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Topic Review
3D Geological Property Modeling Methods
Three-dimensional (3D) geological property modeling is used to quantitatively characterize various geological attributes in 3D space based on geostatistics with the help of computer visualization technology, and the results are often stored in grid data. The 3D geological property modeling includes two main components, grid model generation and property interpolation.
  • 2.7K
  • 15 Jun 2022
Topic Review
Definition and Mechanistic Description of Urban-Rural Integration Development
Urban-rural integration has been found to be an inevitable trend in the development of urban-rural relations and a vital measure to tackle the unbalanced and uncoordinated development between urban and rural areas. The urban–rural relationship is a vital issue in human social development and has aroused wide attention from scholars worldwide. Urban-rural integration is an advanced stage in the development of urban-rural relations and reflects the evolution of urban-rural relations, which can be traced back to the urban-rural development concept of the ideal socialists.
  • 2.7K
  • 27 Jul 2022
Topic Review
Shorebird in West and East Coast of India
Shorebirds constitute a highly diverse group of migrant species that require a high amount of energy in association with their long-distance migration. They are documented in nearly all shorelines of the world except Antarctica. The seasonal migration of shorebirds is an important biological event, characterized by long-distance travel among breeding, stopover and wintering sites driven by seasonal influences on resources. 
  • 2.7K
  • 01 Nov 2022
Topic Review
Factors that Affect Happiness
Happiness is a crucial human disposition that denotes a construct characterizing positive feelings in individuals and overall well-being. It can be perceived as a relatively stable state linked to diverse facets of an individual’s life and distinguishes itself from more transient emotions like joy or sadness. The comprehension of happiness holds significant importance in philosophical, psychological, scholarly, narrative, and governmental spheres, but conclusive agreement regarding the factors that genuinely engender happiness remains elusive. Happiness is “commonly understood as how much one likes the life one lives” . While the meaning and attainment of happiness may differ from person to person, levels of happiness also often fluctuate from one day to the next, and a pandemic such as COVID-19 is likely to change the dynamics of existing happiness.
  • 2.7K
  • 11 Jul 2023
Topic Review
Tungsten Resources in Mine Waste
Tungsten is recognized as a critical metal due to its unique properties, economic importance, and limited sources of supply. It has wide applications where hardness, high density, high wear, and high-temperature resistance are required, such as in mining, construction, energy generation, electronics, aerospace, and defense sectors. The two primary tungsten minerals, and the only minerals of economic importance, are wolframite and scheelite. Secondary tungsten minerals are rare and generated by hydrothermal or supergene alteration rather than by atmospheric weathering. There are no reported concerns for tungsten toxicity. However, tungsten tailings and other residues may represent severe risks to human health and the environment. Tungsten metal scrap is the only secondary source for this metal but reprocessing of tungsten tailings may also become important in the future.
  • 2.7K
  • 12 Jul 2021
Topic Review
Volcanology of Mars
Volcanic activity, or volcanism, has played a significant role in the geologic evolution of Mars. Scientists have known since the Mariner 9 mission in 1972 that volcanic features cover large portions of the Martian surface. These features include extensive lava flows, vast lava plains, and the largest known volcanoes in the Solar System. Martian volcanic features range in age from Noachian (>3.7 billion years) to late Amazonian (< 500 million years), indicating that the planet has been volcanically active throughout its history, and some speculate it probably still is so today. Both Earth and Mars are large, differentiated planets built from similar chondritic materials. Many of the same magmatic processes that occur on Earth also occurred on Mars, and both planets are similar enough compositionally that the same names can be applied to their igneous rocks and minerals. Volcanism is a process in which magma from a planet's interior rises through the crust and erupts on the surface. The erupted materials consist of molten rock (lava), hot fragmental debris (tephra or ash), and gases. Volcanism is a principal way that planets release their internal heat. Volcanic eruptions produce distinctive landforms, rock types, and terrains that provide a window on the chemical composition, thermal state, and history of a planet's interior. Magma is a complex, high-temperature mixture of molten silicates, suspended crystals, and dissolved gases. Magma on Mars likely ascends in a similar manner to that on Earth. It rises through the lower crust in diapiric bodies that are less dense than the surrounding material. As the magma rises, it eventually reaches regions of lower density. When the magma density matches that of the host rock, buoyancy is neutralized and the magma body stalls. At this point, it may form a magma chamber and spread out laterally into a network of dikes and sills. Subsequently, the magma may cool and solidify to form intrusive igneous bodies (plutons). Geologists estimate that about 80% of the magma generated on Earth stalls in the crust and never reaches the surface. As magma rises and cools, it undergoes many complex and dynamic compositional changes. Heavier minerals may crystallize and settle to the bottom of the magma chamber. The magma may also assimilate portions of host rock or mix with other batches of magma. These processes alter the composition of the remaining melt, so that any magma reaching the surface may be chemically quite different from its parent melt. Magmas that have been so altered are said to be "evolved" to distinguish them from "primitive" magmas that more closely resemble the composition of their mantle source. (See igneous differentiation and fractional crystallization.) More highly evolved magmas are usually felsic, that is enriched in silica, volatiles, and other light elements compared to iron- and magnesium-rich (mafic) primitive magmas. The degree and extent to which magmas evolve over time is an indication of a planet's level of internal heat and tectonic activity. The Earth's continental crust is made up of evolved granitic rocks that developed through many episodes of magmatic reprocessing. Evolved igneous rocks are much less common on cold, dead bodies such as the Moon. Mars, being intermediate in size between the Earth and the Moon, is thought to be intermediate in its level of magmatic activity. At shallower depths in the crust, the lithostatic pressure on the magma body decreases. The reduced pressure can cause gases (volatiles), such as carbon dioxide and water vapor, to exsolve from the melt into a froth of gas bubbles. The nucleation of bubbles causes a rapid expansion and cooling of the surrounding melt, producing glassy shards that may erupt explosively as tephra (also called pyroclastics). Fine-grained tephra is commonly referred to as volcanic ash. Whether a volcano erupts explosively or effusively as fluid lava depends on the composition of the melt. Felsic magmas of andesitic and rhyolitic composition tend to erupt explosively. They are very viscous (thick and sticky) and rich in dissolved gases. Mafic magmas, on the other hand, are low in volatiles and commonly erupt effusively as basaltic lava flows. However, these are only generalizations. For example, magma that comes into sudden contact with groundwater or surface water may erupt violently in steam explosions called hydromagmatic (phreatomagmatic or phreatic) eruptions. Erupting magmas may also behave differently on planets with different interior compositions, atmospheres, and gravitational fields.
  • 2.7K
  • 23 Nov 2022
Topic Review
The Subconjunctival Space of the Eye
The subconjunctival space is the hydrophilic, fluid-filled space between the conjunctiva and the sclera. Additionally, the subconjunctival space has access to all the blood vessels found in the conjunctiva, which can help to further distribute substances throughout the whole eye. The subconjunctival space is located superior to the cornea and optimally located to distribute drugs to several different parts of the eye through minimally invasive means while limiting the development of scar tissue.
  • 2.7K
  • 05 May 2022
Topic Review
Implication of P38 MAPK in drugs of abuse and stress
p38 mitogen-activated protein kinases (MAPKs) are key signaling molecules in cellular responses to external stresses and regulation of pro-inflammatory cytokines. Some studies have suggested that p38 MAPK in the region of the nucleus accumbens is involved in abnormal behavioral responses induced by drugs of abuse. In this entry, we recapitulate the role of the p38 MAPK in the rewarding effects of drugs of abuse. We also summarize the implication of p38 MAPK in stress, anxiety, and depression. We opine that p38 MAPK activation is more closely associated to stress-induced aversive responses rather than drug effects per se, in particular cocaine. p38 MAPK is only involved in cocaine reward, predominantly when promoted by stress. Downstream substrates of p38 that may contribute to the p38 MAPK associated-behavioral responses are proposed. Finally, we suggest p38 MAPK inhibitors as possible therapeutic interventions against stress-related disorders by potentially increasing resilience against stress and addiction relapse induced by adverse experiences.
  • 2.7K
  • 15 Jul 2020
Topic Review
5-Hydroxymethylfurfural (HMF)
HMF, an indispensable member of the furan-based platform compound, known as the “sleeping giant”, is a bridge between renewable biomass and industrial bulk chemicals. In recent years, the catalytic transformation of biomass to HMF has been widely studied and envisaged to be hopeful in achieving sustainable biorefineries. The synthesis of HMF from biomass requires the acid hydrolysis of biomass to hexose, and then dehydration of hexose, to obtain HMF. In the second step of dehydration, starting from ketohexose (fructose) is more efficient than starting from aldohexose (glucose).
  • 2.7K
  • 11 Oct 2021
Topic Review
Luxembourg Leaks
Luxembourg Leaks (sometimes shortened to Lux Leaks or LuxLeaks) is the name of a financial scandal revealed in November 2014 by a journalistic investigation conducted by the International Consortium of Investigative Journalists. It is based on confidential information about Luxembourg's tax rulings set up by PricewaterhouseCoopers from 2002 to 2010 to the benefits of its clients. This investigation resulted in making available to the public tax rulings for over three hundred multinational companies based in Luxembourg. The LuxLeaks' disclosures attracted international attention and comment about tax avoidance schemes in Luxembourg and elsewhere. This scandal contributed to the implementation of measures aiming at reducing tax dumping and regulating tax avoidance schemes beneficial to multinational companies. The judicial aspects of this case concern the persons charged by Luxembourg justice for participating in the revelations. No multinational company was charged. The LuxLeaks trial took place in spring 2016 and led to the condemnation of the two whistleblowers. The appeal trial's judgment was delivered in March 2017, upholding monetary fines and reducing the suspended jail sentence for Deltour.
  • 2.7K
  • 25 Oct 2022
Topic Review
Potato Affected by Heat and Drought Stress
Potato crop species are highly prone to different abiotic (high-temperature stress, drought, salinity, and mineral stress).
  • 2.7K
  • 01 Nov 2022
Topic Review
Shellshock (Software Bug)
Shellshock, also known as Bashdoor, is a family of security bugs in the Unix Bash shell, the first of which was disclosed on 24 September 2014. Shellshock could enable an attacker to cause Bash to execute arbitrary commands and gain unauthorized access to many Internet-facing services, such as web servers, that use Bash to process requests. On 12 September 2014, Stéphane Chazelas informed Bash's maintainer Chet Ramey of his discovery of the original bug, which he called "Bashdoor". Working with security experts, Mr. Chazelas developed a patch (fix) for the issue, which by then had been assigned the vulnerability identifier CVE-2014-6271. The existence of the bug was announced to the public on 2014-09-24, when Bash updates with the fix were ready for distribution. The bug Chazelas discovered caused Bash to unintentionally execute commands when the commands are concatenated to the end of function definitions stored in the values of environment variables. Within days of its publication, a variety of related vulnerabilities were discovered (CVE-2014-6277, CVE-2014-6278, CVE-2014-7169, CVE-2014-7186 and CVE-2014-7187). Ramey addressed these with a series of further patches. Attackers exploited Shellshock within hours of the initial disclosure by creating botnets of compromised computers to perform distributed denial-of-service attacks and vulnerability scanning. Security companies recorded millions of attacks and probes related to the bug in the days following the disclosure. Because of the potential to compromise millions of unpatched systems, Shellshock was compared to the Heartbleed bug in its severity.
  • 2.7K
  • 18 Nov 2022
Topic Review
Plant Extract-Mediated Synthesis and Characterization of Nanoparticles
Eucalyptus globulus (EG) is an endemic plant in Australia that is widely found throughout the world. It is the main source of botanical essential oils and is well-recognized in pharmacopeia around the globe. In the plant-assisted fabrication of nanoparticles, the salt solution and extract are simply mixed at room temperature or slightly high temperature, resulting in the synthesis of nanoparticles (NPs) within minutes.
  • 2.7K
  • 13 Jul 2023
Topic Review
A Low-Cost, Flexible Pressure Capacitor Sensor using Polyurethane for Wireless Vehicle Detection
Detection of vehicles on the road can contribute to the establishment of an intelligent transportation management system to allow smooth transportation and the reduction of road accidents. Thus far, an efficient and low-cost polymer flexible pressure sensor for vehicle detection is lacking. This paper presents a flexible sensor for vehicle sensing and demonstrates a wireless system for monitoring vehicles on the road. A vehicle sensor is fabricated by sandwiching a polyurethane material between Aluminum top/bottom electrodes. The sensing mechanism is based on changes in capacitance due to variation in the distance between the two electrodes at an applied external pressure. A clear response against a pressure load of 0.65 Mpa is observed, which is the same pressure as that of the car tire area in contact with the road. Significantly, the sensor is easy to embed on the road line due to its mechanical flexibility and large size. A field test is carried out by embedding the sensor on the road and crossing the sensor with a car. Moreover, the signal displayed on the tablet indicates that the sensing system can be used for wireless detection of the axle, speed, or weight of the vehicle on the road. The findings suggest that the flexible pressure sensor is a promising tool for use as a low-cost vehicle detector in future intelligent transportation management.
  • 2.7K
  • 28 Oct 2020
Topic Review
PD-1/PD-L1 antibody plus Anti-VEGF Inhibitors
A successful phase III trial for the combination of atezolizumab and bevacizumab (the IMbrave150 trial) in advanced hepatocellular carcinoma has recently been reported to show better survival benefit over sorafenib, standard of care for more than 12 years. This is a practice changing results and scientific rationale of this combination, PD-1/PD-L1 antibody plus anti-VEGF inhibitors is very important.
  • 2.7K
  • 18 Dec 2020
Topic Review
Light and Health
Light is important for visual performance and safety, and also plays a vital role in regulating human physiological functions. Poor housing is an important determinant of poor health. One key aspect of housing quality is lighting.
  • 2.7K
  • 16 Feb 2021
Topic Review
Understanding Pet Food Attribute Preferences of US Consumers
This encyclopedia entry is dedicated to pet food attributes and builds on the work of Meike Rombach and David Dean. Partial least squares structural equation modelling shows that pet food purchase involvement positively impacts subjective and objective knowledge about pet food. Subjective knowledge appears to be the strongest factor impacting the importance consumers place on all three attributes. This is followed by objective knowledge. Socio-demographic factors such as gender, age, income, and education appear to have a limited impact as predictors for the importance consumers place on the product attributes.
  • 2.7K
  • 17 Jan 2022
Topic Review
Methods for Crowd Counting
The crowd counting task has become a pillar for crowd control as it provides information concerning the number of people in a scene. It is helpful in many scenarios such as video surveillance, public safety, and future event planning. To solve such tasks, researchers have proposed different solutions. In the beginning, researchers went with more traditional solutions, then the focus is on deep learning methods and, more specifically, on Convolutional Neural Networks (CNNs), because of their efficiency. 
  • 2.7K
  • 21 Jul 2022
Biography
Greg Winter
Sir Gregory Paul Winter CBE FRS FMedSci (born 14 April 1951)[1][2] is a Nobel Prize-winning British biochemist best known for his work on the therapeutic use of monoclonal antibodies. His research career has been based almost entirely at the MRC Laboratory of Molecular Biology and the MRC Centre for Protein Engineering, in Cambridge, England. He is credited with invented techniques to both human
  • 2.7K
  • 16 Nov 2022
Topic Review
Application of Silver in Medicine and Pharmacy
In the context of the growing resistance of microorganisms to available, widely used antibiotics, silver plays a key role. There is only one known case of bacterial resistance to silver—the Pseudomonas stutzeri strain, which naturally occurs in silver mines. The development of research in the field of coordination chemistry offers great opportunities in the design of new substances in which silver ions can be incorporated. 
  • 2.7K
  • 06 Nov 2023
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