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Topic Review
Adipose tissue in the breast
       Breast is a dynamic organ mainly composed of adipose and fibroglandular tissues. The adipose tissue extends from the collarbone to the underarm and around the center of the ribcage. Adipose tissue as an endocrine organ constantly affects the dynamics of the breast. However, the role of adipose tissue in breast has been mostly studied in terms of obesity and cancer.  In this review, we have discussed the role of breast adipose tissue in breast development from embryonic stage to mature breast. Further, we draw attention to the involvement of breast adipose tissue in pregnancy, lactation and involution associated breast changes. Finally, we depict how breast adipose tissue can affect breast cancer. 
  • 5.2K
  • 26 Aug 2020
Topic Review
Global Warming
Global warming is the ongoing rise of the average temperature of the Earth's climate system. It is a major aspect of climate change which, in addition to rising global surface temperatures, also includes its effects, such as changes in precipitation. While there have been prehistoric periods of global warming, observed changes since the mid-20th century have been unprecedented in rate and scale. The Intergovernmental Panel on Climate Change (IPCC) concluded that "human influence on climate has been the dominant cause of observed warming since the mid-20th century". These findings have been recognized by the national science academies of major nations and are not disputed by any scientific body of national or international standing. The largest human influence has been the emission of greenhouse gases, with over 90% of the impact from carbon dioxide and methane. Fossil fuel burning is the principal source of these gases, with agricultural emissions and deforestation also playing significant roles. Climate sensitivity to these gases is affected by feedbacks, such as loss of snow cover, increased water vapour, and melting permafrost. Land surfaces are heating faster than the ocean surface, leading to heat waves, wildfires, and the expansion of deserts. Increasing atmospheric energy and rates of evaporation are causing more intense storms and weather extremes, damaging infrastructure and agriculture. Surface temperature increases are greatest in the Arctic and have contributed to the retreat of glaciers, permafrost, and sea ice. Environmental impacts include the extinction or relocation of many species as their ecosystems change, most immediately in coral reefs, mountains, and the Arctic. Surface temperatures would stabilize and decline a little if emissions were cut off, but other impacts will continue for centuries, including rising sea levels from melting ice sheets, rising ocean temperatures, and ocean acidification from elevated levels of carbon dioxide. Mitigation efforts to address global warming include the development and deployment of low carbon energy technologies, policies to reduce fossil fuel emissions, reforestation, forest preservation, as well as the development of potential climate engineering technologies. Societies and governments are also working to adapt to current and future global warming impacts, including improved coastline protection, better disaster management, and the development of more resistant crops. Countries work together on climate change under the umbrella of the United Nations Framework Convention on Climate Change (UNFCCC), which has near-universal membership. The goal of the convention is to "prevent dangerous anthropogenic interference with the climate system". The IPCC has stressed the need to keep global warming below 1.5 °C (2.7 °F) compared to pre-industrial levels in order to avoid some irreversible impacts. With current policies and pledges, global warming by the end of the century is expected to reach about 2.8 °C (5.0 °F). At the current greenhouse gas (GHG) emission rate, the carbon budget for staying below 1.5 °C (2.7 °F) would be exhausted by 2028.
  • 5.2K
  • 12 Oct 2022
Topic Review
Will
Will, generally, is a faculty of the mind - within philosophy, will is important as one of the parts of the mind, along with reason and understanding. It is considered central to the field of ethics because of its role in enabling deliberate action. One of the recurring questions discussed in the Western philosophical tradition is that of free will - and the related, but more general notion of fate - which asks how the will can be truly free if a person's actions have either natural or divine causes which determine them. In turn, this is directly connected to discussions on the nature of freedom and to the problem of evil.
  • 5.2K
  • 11 Oct 2022
Topic Review
Synergism (Theology)
In Christian theology, synergism is the position of those who hold that salvation involves some form of cooperation between divine grace and human freedom. It stands opposed to monergism, a doctrine most commonly associated with the Lutheran and Reformed Protestant traditions, whose soteriologies have been strongly influenced by the North African bishop and Latin Church Father Augustine of Hippo (354–430). Lutheranism, however, confesses a monergist salvation and synergist damnation (see below). Synergism is upheld by the Orthodox and Roman Catholic Churches, and by the Methodist and Pentecostal traditions of Protestantism. It is an integral part of Arminian theology. Synergism and semipelagianism each teach some collaboration in salvation between God and man, but semipelagian thought teaches that the beginning half of faith is an act of human will. The Council of Orange (529), Lutheran Formula of Concord (1577), and other local councils each condemned semipelagianism as heresy.
  • 5.2K
  • 24 Nov 2022
Topic Review
Forgetting
Forgetting or disremembering is the apparent loss or modification of information already encoded and stored in an individual's short or long-term memory. It is a spontaneous or gradual process in which old memories are unable to be recalled from memory storage. Problems with remembering, learning and retaining new information are a few of the most common complaints of older adults. Studies show that retention improves with increased rehearsal. This improvement occurs because rehearsal helps to transfer information into long-term memory. Forgetting curves (amount remembered as a function of time since an event was first experienced) have been extensively analyzed. The most recent evidence suggests that a power function provides the closest mathematical fit to the forgetting function.
  • 5.2K
  • 09 Oct 2022
Topic Review
Pathophysiology-Based Traumatic Brain Injury
Traumatic brain injury (TBI) is a leading cause of disability and death among children and young adults, with an incidence of approximately 1.7 million per year in the USA, resulting in 52,000 deaths. Survivors of the initial impact must still contend with the consequences of trauma, as not all injury occurs at the time of impact. The primary injury results from forces applied to the head and involve direct structural damage to the brain. This triggers a cascade of events leading to neurological damage that evolves secondary injury. Several external brain insults, both intracranial and systemic, may complicate and worsen the secondary injury.
  • 5.2K
  • 07 Mar 2024
Topic Review
Removal of Purines from Beer
Beer corresponds to a fermented alcoholic beverage composed of several components, including purine compounds. These molecules, when ingested by humans, can be catabolized into uric acid, contributing to uric acid’s level increase in serum, which may lead to hyperuricemia and gout. To assure a proper management of this disease, physicians recommend restrictive dietary measures, particularly by avoiding the consumption of beer. Therefore, it is of relevance to develop efficient methods to remove purine compounds from alcoholic beverages such as beer. There are several enzymatic, biological, and adsorption methods reported envisaging purine compounds’ removal. Some enzymatic and biological methods present drawbacks, which can be overcome by adsorption methods. Within adsorption methods, adsorbent materials, such as activated carbon or charcoal, have been reported and applied to beer or wort samples, showing an excellent capacity for adsorbing and removing purine compounds. By ensuring the selective removal of purine compounds from this beverage, beer can be taken by hyperuricemic and gouty patients, avoiding restrictive dietary measures, while decreasing the related healthcare economic burden. 
  • 5.2K
  • 23 Nov 2021
Topic Review
Panopticon
The Panopticon is a type of institutional building and a system of control designed by the English philosopher and social theorist Jeremy Bentham in the late 18th century. The scheme of the design is to allow all (pan-) inmates of an institution to be observed (-opticon) by a single watchman without the inmates being able to tell whether or not they are being watched. Although it is physically impossible for the single watchman to observe all the inmates' cells at once, the fact that the inmates cannot know when they are being watched means that they are motivated to act as though they are being watched at all times. Thus, they are effectively compelled to regulate their own behaviour. The name may also allude to the many-eyed giant Panoptes in Greek mythology, some of whose eyes were always awake, making him a highly effective watchman. The design consists of a circular structure with an "inspection house" at its centre, from which the manager or staff of the institution is able to watch the inmates. The inmates, who are stationed around the perimeter of the structure, are unable to see into the inspection house. Bentham conceived the basic plan as being equally applicable to hospitals, schools, sanatoriums, and asylums, but he devoted most of his efforts to developing a design for a Panopticon prison. It is his prison that is now most widely meant by the term "panopticon". Bentham described the Panopticon as "a new mode of obtaining power of mind over mind, in a quantity hitherto without example". Elsewhere, in a letter, he described the Panopticon prison as "a mill for grinding rogues honest".
  • 5.2K
  • 24 Nov 2022
Topic Review
Paraprobiotics
Paraprobiotics are defined as “inactivated microbial cells (non-viable) that confer a health benefit to the consumer” and hold the ability to regulate the adaptive and innate immune systems, to exhibit anti-inflammatory, antiproliferative and antioxidant properties, and to exert antagonistic effect against pathogens, thus confirming that viability of probiotics is not an absolute pre-requisite for promoting health effects. 
  • 5.2K
  • 05 May 2021
Topic Review
DENGUE and ZIKA Flaviviruses Nucleic Acid Vaccine
Dengue virus and Zika virus are mosquito-borne, single-stranded, positive-sense RNA viruses that belong to the Flaviviridae family. Both the viruses are closely related and have similarities with other flaviviruses. Dengue virus (DENV) causes a severe febrile illness with fever, joint pain, and rash leading to a life-threatening condition in severe cases. While Zika virus (ZIKV) primarily causes mild fever, it can be passed from a pregnant mother to her fetus, resulting in severe birth defect microcephaly and even causing a rare autoimmune disease—Guillain–Barre syndrome. 
  • 5.2K
  • 08 Jun 2022
Topic Review
Odor Removal Technologies
Comparing various methods of odor removal, undoubtedly biological methods of pollution degrada-tion have an advantage over others—chemical and physical. This advantage is manifestedmainly in ecological and economic terms. The possibility of using biological methods to remove H2S and NH3, as the most common emitted by the municipal sector companies, was analyzed in terms of their removal efficiency. The method of bio-purification of air in biotrickling filters is more advan-tageous than the others, due to the high effectiveness of VOCs and odors degradation, lack of secondary pollutants, and economic aspects—it is a method competitive to the commonly used air purification method in biofilters.
  • 5.2K
  • 12 Apr 2021
Topic Review
Specific Relative Angular Momentum
In celestial mechanics the specific relative angular momentum [math]\displaystyle{ \vec{h} }[/math] plays a pivotal role in the analysis of the two-body problem. One can show that it is a constant vector for a given orbit under ideal conditions. This essentially proves Kepler's second law. It's called specific angular momentum because it's not the actual angular momentum [math]\displaystyle{ \vec{L} }[/math], but the angular momentum per mass. Thus, the word "specific" in this term is short for "mass-specific" or divided-by-mass: Thus the SI unit is: m2·s−1. [math]\displaystyle{ m }[/math] denotes the reduced mass [math]\displaystyle{ \frac{1}{m} = \frac{1}{m_1}+\frac{1}{m_2} }[/math].
  • 5.2K
  • 11 Nov 2022
Topic Review
Spilled Oil in Marine Environment
Oil spill is a widespread environmental problem with significant ecological impacts. When oil is spilled in the sea,  it undergoes different  degradation processes such as dispersion, photooxidation, evaporation, dissolution, emulsion, biodegradation and other weathering processes. The most important among these processes is biodegradation, which is facilitated by naturally occurring oil-degrading bacteria.  The interaction of bacteria with hydrocarbons in oil is affected by different environmental factors.  Several studies have evaluated the effects of each factor on the biodegradation of the oil by bacterial, but none has taken all these factors together.
  • 5.2K
  • 06 Apr 2022
Topic Review
IoT-Enabled Smart Agriculture
The growth of the global population coupled with a decline in natural resources, farmland, and the increase in unpredictable environmental conditions leads to food security is becoming a major concern for all nations worldwide. These problems are motivators that are driving the agricultural industry to transition to smart agriculture with the application of the Internet of Things (IoT) and big data solutions to improve operational efficiency and productivity. The IoT integrates a series of existing state-of-the-art solutions and technologies, such as wireless sensor networks, cognitive radio ad hoc networks, cloud computing, big data, and end-user applications. IoT is defined as the network of all objects that are embedded within devices, sensors, machines, software and people through the Internet environment to communicate, exchange information and interact in order to provide a comprehensive solution between the real world and the virtual world.
  • 5.2K
  • 01 Apr 2022
Topic Review
Cervical Imaging in the Low Resource Setting
Cervical cancer is one of the most significant global health inequities of our time and is the fourth most common cancer in women worldwide, disproportionally affecting developing countries where the disease burden is 84%. Sometimes referred to as a preventable cancer, it progresses slowly, providing a window of time for routine screening in which pre-cancerous lesions can be identified and treated.
  • 5.2K
  • 08 Nov 2022
Topic Review
Sutra
Sutra (Sanskrit: सूत्र, romanized: sūtra, lit. 'string, thread') in Indian literary traditions refers to an aphorism or a collection of aphorisms in the form of a manual or, more broadly, a condensed manual or text. Sutras are a genre of ancient and medieval Indian texts found in Hinduism, Buddhism and Jainism. In Hinduism, sutras are a distinct type of literary composition, a compilation of short aphoristic statements. Each sutra is any short rule, like a theorem distilled into few words or syllables, around which teachings of ritual, philosophy, grammar, or any field of knowledge can be woven. The oldest sutras of Hinduism are found in the Brahmana and Aranyaka layers of the Vedas. Every school of Hindu philosophy, Vedic guides for rites of passage, various fields of arts, law, and social ethics developed respective sutras, which help teach and transmit ideas from one generation to the next. In Buddhism, sutras, also known as suttas, are canonical scriptures, many of which are regarded as records of the oral teachings of Gautama Buddha. They are not aphoristic, but are quite detailed, sometimes with repetition. This may reflect a philological root of sukta (well spoken), rather than sutra (thread). In Jainism, sutras also known as suyas are canonical sermons of Mahavira contained in the Jain Agamas as well as some later (post-canonical) normative texts.
  • 5.2K
  • 13 Nov 2022
Topic Review
Non-Alcoholic Fermented Cereal Beverage
Fermentation continues to be the most common biotechnological tool to be used in cereal-based beverages, as it is relatively simple and economical. Fermented beverages hold a long tradition and have become known for their sensory and health-promoting attributes. Considering the attractive sensory traits and due to increased consumer awareness of the importance of healthy nutrition, the market for functional, natural, and non-alcoholic beverages is steadily increasing all over the world. This paper outlines the current achievements and technological development employed to enhance the qualitative and nutritional status of non-alcoholic fermented cereal beverages (NFCBs). Following an in-depth review of various scientific publications, current production methods arediscussed as having the potential to enhance the functional properties of NFCBs and their safety, as a promising approach to help consumers in their efforts to improve their nutrition and health status. Moreover, key aspects concerning production techniques, fermentation methods, and the nutritional value of NFCBs are highlighted, together with their potential health benefits and current consumption trends. Further research efforts are required in the segment of traditional fermented cereal beverages to identify new potentially probiotic microorganisms and starter cultures, novel ingredients as fermentation substrates, and to finally elucidate the contributions of microorganisms and enzymes in the fermentation process.
  • 5.2K
  • 02 Sep 2020
Topic Review
Molybdenum Disulfide
Molybdenum disulfide (MoS2) is one of the compounds discussed nowadays due to its outstanding properties that allowed its usage in different applications. Its band gap and its distinctive structure make it a promising material to substitute graphene and other semiconductor devices. It has different applications in electronics especially sensors like optical sensors, biosensors, electrochemical biosensors that play an important role in the detection of various diseases’ like cancer and Alzheimer. It has a wide range of energy applications in batteries, solar cells, microwave, and Terahertz applications. It is a promising material on a nanoscale level, with favorable characteristics in spintronics and magnetoresistance. 
  • 5.2K
  • 24 May 2021
Topic Review
Production Methods of Peptides
Peptides are organic polymers composed of 2–50 amino acids linked to each other by means of covalent amide (=peptide) bonds. The composition, length and sequence of the amino acid chain have a dramatic influence on the activity of the peptide itself, for example in the human body. Peptides are called bioactive if they have a beneficial impact on body functions, on biological processes and, as a consequence, on health. The main production methods to obtain peptides are enzymatic hydrolysis, microbial fermentation, recombinant approach and, especially, chemical synthesis. 
  • 5.2K
  • 01 Sep 2021
Topic Review
Jaguar S-Type
The Jaguar S-Type was an executive car that debuted at the 1998 Birmingham Motor Show and was marketed by Jaguar for model years 1999-2008, reviving the nameplate of the company's 1963-68 S-Type as a four-door notchback saloon. The S-Type received a mild facelift for model year 2005. The 2002 S-Type 4.2 Supercharged V8 at the time, was the fastest road production saloon car in the world. The S-Type was discontinued in late 2007 and replaced by the XF.
  • 5.2K
  • 09 Nov 2022
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