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Topic Review
Blockchain Technology in Automobile Supply Chain
A robust traceability system would help organizations in inventory optimization reduce lead time and improve customer service and quality which further enables the organizations to be a leader in their industry sector. The traceability issues and waiting time at different nodes of the supply chain are considered to be priority issues that affect the overall supply chain efficiency in the automotive supply chain.  A new blockchain-based architecture was provided to improve traceability and reduce waiting time for the automotive supply chain. 
  • 2.1K
  • 06 Jan 2022
Topic Review
Biobeneficiation of PGMs
Conventional beneficiation of the Platinum Group of Metals (PGMs) relies on the use of inorganic chemicals. With the depreciation of high grade deposits, these conventional processes are becoming less economically viable. Furthermore, the use of chemicals has serious negative impacts on the environment. To address the challenges of conventional PGM beneficiation, biobeneficiation has been proposed. Bio-beneficiation is the concentration of mineral species by employing microorganisms that interact with either the gangue or the valuable mineral species. Bio-beneficiation can also be described as the use of microorganisms to interact with minerals to subsequently induce processes such as magnetic separation, flotation, and flocculation.
  • 2.1K
  • 19 Jan 2022
Topic Review
Various Uses of Lycopene
Lycopene is a carotenoid abundantly found in red vegetables. This natural pigment displays an important role in human biological systems due to its excellent antioxidant and health-supporting functions, which show a protective effect against cardiovascular diseases, hypertension, cancers, and diabetes.
  • 2.1K
  • 28 Feb 2022
Topic Review
Bioterrorism
Bioterrorism is the deliberate release of viruses, bacteria, toxins or other harmful agents to cause illness or death in people, animals, or plants.
  • 2.1K
  • 10 Nov 2022
Topic Review
Transposon
Transposons are sequences of DNA that can move around to different positions within the genome of a single cell, a process called transposition. In the process, they can cause mutations and change the amount of DNA in the genome. Transposons are also called "jumping genes" or "mobile genetic elements". Discovered by Barbara McClintock early in her career, the topic went on to be a Nobel winning work in 1983. There are a variety of mobile genetic elements, and they can be grouped based on their mechanism of transposition. Class I mobile genetic elements, or retrotransposons, move in the genome by being transcribed to RNA and then back to DNA by reverse transcriptase, while class II mobile genetic elements move directly from one position to another within the genome using a transposase to "cut and paste" them within the genome. Transposons are very useful to researchers as a means to alter DNA inside of a living organism. Transposons make up a large fraction of genome sizes which is evident through the C-values of eukaryotic species. As an example about 45% of the human genome is composed of transposons and their defunct remnants.
  • 2.1K
  • 23 Nov 2022
Topic Review
Non-Steroidal Anti-Inflammatory Drugs in the Fight against COVID-19
In Italy, a flowchart to be used by General Practitioners for the at-home treatment of patients with COVID-19, has been released. It states that early at-home treatment for SARS-CoV-2 infection is possible due to the availability of specific antiviral drugs to be used in at-risk patients, and that non-steroidal anti-inflammatory drugs (NSAIDs) have an important function in combating the virus. Therefore, the use of NSAIDs is not only rational but also effective in cases that cannot be treated using antivirals. 
  • 2.1K
  • 17 Mar 2023
Topic Review
5-HT2A Receptor Ligands Against Depression
According to the World Health Organization, depression is a multifactorial disorder that affects around 350 million people worldwide. The most widespread monoamine of the CNS-serotonin (5-HT) is believed to play a vital role in the pathomechanism of this condition, and the importance of the neurotransmitter is elevated by the "serotonin hypothesis", linking the presence of the depression-like symptoms with diminished 5-HT concentration in certain brain regions. Serotonin acts its biological effects via numerous receptors. Out of all seven types of serotonin receptors, the serotonin 2A receptor has been identified as a most promising molecular target valuable for the treatment of mood disorders. Recent medicinal chemistry findings on the structure and function of the serotonin 2A (5-HT2A) receptor facilitated design and discovery of novel anti-depressants. 
  • 2.1K
  • 14 Feb 2022
Topic Review
Diversity of Synthetic Dyes
Synthetic dyes are mostly derived from petrochemical compounds, they are commercialized in liquid, powder, pastes, or granule forms. They are endowed with multiple potentialities such as fast and consistent coloration with different classes of fabrics as mentioned in the above section, a wide range of color pigments and shades, facility of manipulation, stability over several external factors and economical energy consumption. Therefore, the majority of synthetic dyes cause harmful impacts when discharged in non-treated or partially treated forms in the environment.
  • 2.1K
  • 06 Aug 2021
Topic Review
Gravitation
In physics, gravitation or gravity is the tendency of objects with mass to accelerate toward each other. Gravitation is one of the four fundamental interactions in nature, the other three being the electromagnetic force, the weak nuclear force, and the strong nuclear force. Gravitation is the weakest of these interactions, but acts over great distances and is always attractive. In classical mechanics, gravitation arises out of the force of gravity (which is often used as a synonym for gravitation). In general relativity, gravitation arises out of spacetime being curved by the presence of mass, and is not a force. In quantum gravity theories, either the graviton is the postulated carrier of the gravitational force, or time-space itself is envisioned as discrete in nature, or both. Classically, the gravitational attraction of the earth endows objects with weight and causes them to fall to the ground when dropped (the earth also moves toward the object, but only by an infinitesimal amount). Moreover, gravitation is the reason for the very existence of the earth, the sun, and other celestial bodies; without it matter would not have coalesced into these bodies and life as we know it would not exist. Gravitation is also responsible for keeping the earth and the other planets in their orbits around the sun, the moon in its orbit around the earth, for the formation of tides, and for various other natural phenomena that we observe.
  • 2.1K
  • 14 Oct 2022
Topic Review
Emeralds from Kagem Mine, Kafubu Area, Zambia
Kagem emerald mine in Zambia is deemed the largest open-pit emerald mine in the world, with extremely high economic value and a large market share. Mineral inclusions typically include actinolite, graphite, magnetite, and dolomite. Black graphite encased in actinolite in Kagem emeralds is reported herein for the first time. The FTIR spectrum of Kagem emeralds reveals that the absorption of type II H2O is stronger than that of type I H2O, indicating the presence of abundant alkali metals, which was confirmed through chemical analysis. Kagem emeralds contain high levels of Na (avg. 16,440 ppm), moderate-to-high Cs (avg. 567 ppm), as well as low-to-moderate K (avg. 185 ppm) and Rb (avg. 14 ppm) concentrations.
  • 2.1K
  • 16 Oct 2023
Topic Review
Interferon-Based Biopharmaceuticals
Interferons are secreted autocrine and paracrine proteins, which by regulating several biochemical pathways have a spectrum of clinical effectiveness against viral infections, malignant diseases, and multiple sclerosis. 
  • 2.1K
  • 16 May 2021
Topic Review
Chordae tendineae in Animal Models
Myxomatous mitral valve disease (MMVD) is the most common canine heart disease in which, among other things, chordae tendineae rupture occurs. The Chordae tendineae (CT) are part of the atrioventricular apparatus. They are mainly responsible for the mechanical functions of heart valves.  In our study we performed biomechanical and histopathological examination of CT in order to better understand the functioning of the valvular apparatus. It is clinically relevant  to begin further studies about biomarkers suggesting an episode of CT rupture, as such an episode leads to acute pulmonary oedema and worsens the clinical status of the patient.
  • 2.1K
  • 24 Jun 2021
Topic Review
Vision-Based Defect Inspection for Sewer Pipes
Underground sewerage systems (USSs) are a vital part of public infrastructure that contributes to collecting wastewater or stormwater from various sources and conveying it to storage tanks or sewer treatment facilities. A healthy USS with proper functionality can effectively prevent urban waterlogging and play a positive role in the sustainable development of water resources. Since it was first introduced in the 1960s, computer vision (CV) has become a mature technology that is used to realize promising automation for sewer inspections.
  • 2.1K
  • 28 Apr 2022
Topic Review
Salicylic Acid in Root Growth and Development
In plants, salicylic acid (SA) is a hormone that mediates a plant’s defense against pathogens. SA also takes an active role in a plant’s response to various abiotic stresses, including chilling, drought, salinity, and heavy metals. In addition, in recent years, numerous studies have confirmed the important role of SA in plant morphogenesis.
  • 2.1K
  • 10 Mar 2022
Topic Review
Cristatusaurus
Cristatusaurus is a genus of theropod dinosaur that lived during the Early Cretaceous Period of what is now Niger, 112 million years ago. It was a baryonychine member of the Spinosauridae, a group of large bipedal carnivores with well-built forelimbs and elongated, crocodile-like skulls. The type species Cristatusaurus lapparenti was named in 1998 by scientists Philippe Taquet and Dale Russell, on the basis of jaw bones and some vertebrae. Two claw fossils were also later assigned to Cristatusaurus. The animal's generic name, which means "crested reptile", alludes to a sagittal crest on top of its snout; while the specific name is in honor of the French paleontologist Albert-Félix de Lapparent. Cristatusaurus is known from the Albian to Aptian Erlhaz Formation, where it would have coexisted with sauropod and iguanodontian dinosaurs, other theropods, and various crocodylomorphs. Originally proposed to be an indeterminate species of Baryonyx, the identity of Cristatusaurus has been subject to debate, in part due to the fragmentary nature of its fossils. Some argue that it is probably the same dinosaur as Suchomimus, which has also been found in Niger, in the same sediment layers. In that case the genus Cristatusaurus would have priority, since it was named two months earlier. Others have concluded, however, that Cristatusaurus is a nomen dubium, considering it indistinguishable from both Suchomimus and Baryonyx. Some distinctions between the fossils of Cristatusaurus and Suchomimus have been pointed out, but it is uncertain whether these differences separate the two genera or if they are due to ontogeny (changes in an organism during growth).
  • 2.1K
  • 29 Sep 2022
Topic Review
Poultry Meat Spoilage and Biogenic Amine Content
Meat is a key element of a balanced diet. Meat consumption has played a significant role in evolution, affecting the development of the human brain. Poultry meat is a source of many important nutrients, micro- and macro-elements, and biologically active substances. During meat storage, many physicochemical changes take place, also affecting the content of biologically active substances, including biogenic amines.
  • 2.1K
  • 04 Jul 2022
Topic Review
A COVID-19 Education Recovery Program
As a consequence of the COVID-19 pandemic, many students have developed substantial educational delays, both cognitively and social-emotionally. To counter such negative effects of the school closures, several policies and support strategies on attainment and social-emotional well-being have been proposed and implemented. In the Netherlands, the focus is on using evidence-based interventions to boost educational achievement. The question is, however, how evidence-based the interventions really are. 
  • 2.1K
  • 23 Jun 2021
Topic Review
Tin-iodate rechargeable battery
The tin-iodate battery is a rechargeable battery for large scale energy storage.
  • 2.1K
  • 04 Jan 2022
Topic Review
Plectranthus neochilus Schltr
Plectranthus neochilus Schltr. (Lamiaceae) is a plant recently introduced in Cuba. Worldwide, it is an ethnomedicinal alternative for its use against microbial infections, but the Cuban population use the extracts to treat sleep disorders. To address this apparent incongruity, four collections (from different seasonal conditions in the year) of Cuban P. neochilus cultivars were analyzed in terms of their pharmacognostic characteristics. 
  • 2.1K
  • 18 Jan 2022
Topic Review
Fundamentals of Path-Planning Algorithms
The rapid technological development of computing power and system operations today allows for increasingly advanced algorithm implementation, as well as path planning in real time.
  • 2.1K
  • 12 Aug 2022
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