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Topic Review
Statistical Analysis of Intensive Care Unit COVID-19 Data
COVID-19 caused a pandemic, due to its ease of transmission and high number of infections. The evolution of the pandemic and its consequences for the mortality and morbidity of populations, especially the elderly, generated several scientific studies and many research projects. Among them, researchers have the Predictive Models of COVID-19 Outcomes for Higher Risk Patients Towards a Precision Medicine (PREMO) research project. For such a project with many data records, it is necessary to provide a smooth graphical analysis to extract value from it.
  • 2.5K
  • 10 Apr 2024
Topic Review
Metal Ions as Signaling Agents
Metal ions can be involved in signaling processes within the cell in both physiological and pathological conditions. Magnesium and calcium are the most recognized signaling agents among metals. Zinc, copper, and iron can also play key roles in signaling pathways. There are many systems in which changes in intra- and extra-cellular zinc and copper concentrations have been linked to important downstream events, especially in nervous signal transduction. Iron signaling is mostly related with its homeostasis. However, it is also involved in a recently discovered type of programmed cell death, ferroptosis.
  • 2.5K
  • 06 Nov 2020
Topic Review
Annus Mirabilis Papers
The Annus mirabilis papers (from Latin annus mīrābilis, "miracle year") are the papers of Albert Einstein published in the Annalen der Physik scientific journal in 1905. These four articles contributed substantially to the foundation of modern physics and changed views on space, time, mass, and energy. The annus mirabilis is often called the "miracle year" in English or Wunderjahr in German. The first paper elucidated the theory of the photoelectric effect; the second paper explained Brownian motion; the third paper introduced special relativity; and the fourth, mass-energy equivalence. Together, these papers substantially advanced the field of modern physics.
  • 2.5K
  • 31 Oct 2022
Topic Review
Role of parasocial relationship (PSR)
       Individuals’ emotional bonds with media performers have impacts on desirable attitudinal and behavioral outcomes. A parasocial relation (PSR) is “a seeming face-to-face relationship” created between a media persona and audience members. PSR has persuasive influence on knowledge, perceptions, and behaviors concerning specific social issues such as health, environment, and politics. Audiences are also likely to perform the behaviors advocated by celebrities and adopt attitudes and beliefs similar to those held by celebrities. 
  • 2.5K
  • 08 Apr 2021
Topic Review
Zebrafish Heart Development
Proper development and function of the vertebrate heart is vital for embryonic and postnatal life. Many congenital heart defects in humans are associated with disruption of genes that direct the formation or maintenance of atrial and pacemaker cardiomyocytes at the venous pole of the heart. Zebrafish are an outstanding model for studying vertebrate cardiogenesis, due to the conservation of molecular mechanisms underlying early heart development, external development, and ease of genetic manipulation.
  • 2.5K
  • 23 Feb 2021
Topic Review
Method of Detecting Perfluorooctanoic Acid
Perfluorooctanoic acid (PFOA) is a new type of organic pollutant in wastewater that is persistent, toxic, and accumulates in living organisms. The development of rapid and sensitive analytical methods to detect PFOA in environmental media is of great importance. Fluorescence detection has the advantages of high efficiency and low cost, in which fluorescent probes have excellent fluorescence properties, excellent bio-solubility, and remarkable photostability. 
  • 2.5K
  • 31 Jan 2023
Topic Review
Anthracnose Caused by Colletotrichum gloeosporioides
Fruits and vegetables are constantly affected by postharvest diseases, of which anthracnose is one of the most severe and is caused by diverse Colletotrichum species, mainly C. gloeosporioides. Colletotrichum gloeosporioides is a cosmopolitan pathogen widely disseminated as a common plant pathogen.
  • 2.5K
  • 26 Jul 2023
Topic Review
A Connected Community Approach to Building Community Resilience
Urban resilience research is recognizing the need to complement a mainstream preoccupation with “hard” infrastructure (electrical grid, storm sewers, etc.) with attention to the “soft” (social) infrastructure issues that include the increased visibility of and role for civil society, moving from (top-down, paternalistic) government to (participatory) governance. Analyses of past shock events invariably point to the need for more concerted efforts in building effective governance and networked relations between civil society groupings and formal institutions before, during, and after crisis. However, the literature contains little advice on how to go about this. A Connected Communities Approach is advanced that offers the missing guidance, and it's key features are explained.
  • 2.5K
  • 20 Oct 2021
Topic Review
Sirtuins
The sirtuin system consists of seven highly conserved regulatory enzymes responsible for metabolism, antioxidant protection, and cell cycle regulation. The great interest in sirtuins is associated with the potential impact on life extension. 
  • 2.5K
  • 05 Jan 2023
Topic Review
Pharmacologic and Clinical Considerations of Nalmefene
Nalmefene is a pure opioid antagonist structurally similar to naltrexone that can serve as an alternative antidote for reversing respiratory depression associated with acute opioid overdose. Nalmefene is also known as 6-methylene naltrexone. Its main features of interest are its prolonged duration of action that surpasses most opioids and its ability to serve as an antidote for acute opioid overdose.
  • 2.5K
  • 29 Mar 2022
Topic Review
Augmented Reality in Agriculture
Augmented Reality (AR) applications have become prevalent within smart industry manufacturing and wider popular culture sectors over the last decade, yet use of AR technology within an agricultural setting is still within its infancy. 
  • 2.5K
  • 04 Jan 2022
Topic Review
Work-Life Balance, Job Performance and Knowledge Risks
Despite the focus on knowledge risks in the literature, a limited number of studies have empirically examined technological knowledge risks in terms of digitalization, old technologies, and cybercrime as moderating variables in the relationship between work-life balance and job performance. To address this gap, this entry investigated the moderation effects of technological knowledge risks on the relationship between work-life balance and job performance during the pandemic period in employees of cooperative credit banks. A quantitative approach that involved gathering surveys was adopted. Applying PLS-SEM, the empirical findings revealed that technological knowledge risks have a significant impact on the relationship between work-life balance and job performance. Additionally, this research encourages managers to create and maintain a healthy work environment that promotes valuable employees’ job performance while also evaluating the use of new technological advances and their related risks.
  • 2.5K
  • 13 Jun 2022
Topic Review
Application of Two-Dimensional Materials towards CMOS-Integrated Gas Sensors
The semiconductor metal oxide (SMO)-based gas sensor, considered the current workhorse of semiconductor-based chemiresistive gas sensor technologies, requires high temperatures to initiate the surface reactions which result in the sensing response, making it difficult to fabricate and prone to high mechanical instability. Therefore, alternatives at lower temperatures are desired, where 2D materials seem to hold the most promise. Even at ambient temperature, their sensitivity is extraordinarily large due to their extremely high surface-to-volume ratio. However, some ongoing issues still need to be resolved before gas sensors based on 2D materials can be widely used and commercialized. The alternative room temperature solutions involve optical signals, either by designing an nondispersive infrared (NDIR) sensor based on the Beer-Lambert law or by introducing an additional UV illumination to SMO sensors. In both cases, complementary metal oxide semiconductor (CMOS) integration is not feasible, which is why continued interest in 2D-material-based gas sensors persists.
  • 2.5K
  • 02 Dec 2022
Topic Review
Windows 10 Version History (Version 1703)
Windows 10 Creators Update (also known as version 1703 and codenamed "Redstone 2") is the third major update to Windows 10 and the second in a series of updates under the Redstone codenames. It carries the build number 10.0.15063.
  • 2.5K
  • 28 Nov 2022
Topic Review
Studio One
Studio One is a digital audio workstation (DAW) application, used to create, record, mix and master music and other audio, with functionality also available for video. Initially developed as a successor to the KRISTAL Audio Engine, it was acquired by PreSonus and first released in 2009 for macOS and Microsoft Windows. In addition to the commercial editions of the software (known as Studio One Artist and Studio One Professional), PreSonus also distributes a free edition, with reduced functionality (known as Studio One Prime). The Professional edition is also available as part of the PreSonus Sphere monthly subscription program.
  • 2.5K
  • 21 Oct 2022
Topic Review
Protein Subcellular Localization
Proteins are localized into different cellular compartments and sub-compartments inside the cell. Each subcellular compartment has a distinct well-defined function in the cell and has a characteristic physicochemical environment, which drives proper functioning of the proteins. Each subcellular compartment has a distinct, well defined function in the cell and is considered to have evolved from the prokaryotic cell. Typical eukaryotic cells have two types of DNAs (i) chromosomal nuclear DNA and (ii) organelle DNA, which is present in mitochondria and chloroplast while prokaryotic cells have only single type of DNA called nucleoid.
  • 2.4K
  • 18 Feb 2021
Topic Review
Cannabis and Male Reproductive Health
Cannabis sativa is a cheap hallucinating agent used in different parts of the world from time unknown as a part of various religious as well as social practices. Cannabis which is a special type of Marijuana can provide temporary relief from analgesia, body pain and in some other clinical conditions. But, impacts of Cannabis on reproductive health of males and females are multi-faceted and differentially fatal. In males, Cannabis can cause changes in testicular morphology, sperm parameters (in terms of semen quality, sperm morphology, sperm mortality and sperm motility), male reproductive hormones and finally causing reduced libido. In females, Cannabis can reduce female fertility by disrupting hypothalamic release of gonadotropin releasing hormone (GnRH), leading to reduced estrogen and progesterone production and anovulatory menstrual cycles.  Current research suggest that cannabis may negatively impact on male and female fertility conditions. However, male sterility considering the Cannabis impact is totally lacking in human as well as in sub-human primates. However, very limited studies are available on Cannabis effect on primate female reproduction considering Rhesus monkeys. Hence, further studies are needed to validate that robust findings in animal models will carry over into human experience.
  • 2.4K
  • 18 Sep 2021
Topic Review
Transglutaminase 2
Transglutaminase 2 (TG2) is a ubiquitously expressed enzyme catalyzing the crosslinking between Gln and Lys residues and involved in various pathophysiological events. Besides this crosslinking activity, TG2 functions as a deamidase, GTPase, isopeptidase, adapter/scaffold, protein disulfide isomerase, and kinase. It also plays a role in the regulation of hypusination and serotonylation.
  • 2.4K
  • 11 Aug 2021
Topic Review
Aluminum Alloy 5083
The semi-solid metal (SSM) 5083 aluminum alloy was developed for part manufacturing in the marine shipbuilding industry and including other industries using this material in the manufacture of parts.
  • 2.4K
  • 08 Oct 2021
Topic Review
Comprehensive Review on Wearable Sweat-Glucose Sensors for CGM
The incidence of diabetes is increasing at an alarming rate, and regular glucose monitoring is critical in order to manage diabetes. Currently, glucose in the body is measured by an invasive method of blood sugar testing. Blood glucose (BG) monitoring devices measure the amount of sugar in a small sample of blood, usually drawn from pricking the fingertip, and placed on a disposable test strip. Therefore, there is a need for non-invasive continuous glucose monitoring, which is possible using a sweat sensor-based approach.
  • 2.4K
  • 18 Jan 2022
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