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Topic Review
PC-12 Cell Line
PC-12 cells have been widely used as a neuronal line study model in many biosensing devices, mainly due to the neurogenic characteristics acquired after differentiation, such as high level of secreted neurotransmitter, neuron morphology characterized by neurite outgrowth, and expression of ion and neurotransmitter receptors. 
  • 2.7K
  • 18 Jul 2022
Topic Review
Apricot
Fruits maintain the image as the richest sources of vitamins. Focusing on apricots, utilization of apricot species for many applications is possible due to its various benefits. Many research studies demonstrated different perspectives of apricot, especially in medical used as it can act as antioxidant, anti-inflammatory, and antimicrobial agents. Moreover, in the industrial sectors, apricots can be used in the production of biofuels and batteries.
  • 2.7K
  • 18 Aug 2022
Topic Review
Methane Combustion's Chemical Kinetic Mechanisms
Methane is an important fuel for gas turbine and gas engine combustion, and the most common fuel in fundamental combustion studies. As Computational Fluid Dynamics (CFD) modeling of combustion becomes increasingly important, so do chemical kinetic mechanisms for methane combustion. 
  • 2.7K
  • 03 Jun 2021
Topic Review
Large-Scale Geothermal Collector Systems
A Geothermal collector system is a ground heat exchanger connected to a heat pump which provides heating energy from the ground for buildings. A Large-scale geothermal collector systems differ from small systems, which are usually built for individual buildings, in their size and complexity. Typical large-scale geothermal collector systems supply entire settlements with heating and cooling energy via 5th Generation District Heating and Cooling (5GDHC) by using the very Shallow Geothermal Potential (vSGP). They can also be constructed in multiple horizontal layers.
  • 2.7K
  • 04 Mar 2022
Topic Review
Hamburger Flugzeugbau HFB 320 Hansa Jet
The HFB 320 Hansa Jet is a twin-engine, ten-seat business jet that was designed and produced by Germany aircraft manufacturer Hamburger Flugzeugbau between 1964 and 1973. The most recognisable and unconventional feature of the aircraft is its forward-swept wing. The Hansa Jet begun development during the 1960s, the selection of the forward-swept wing can be largely attributed to head engineer Hans Wocke, who had previously worked on the experimental Junkers Ju 287. It possessed a spacious cabin, which was achieved due to its wing design, but was a relatively heavy aircraft, posing some issues during both take-off and landing. On 21 April 1964, the prototype conducted its maiden flight. On 12 May 1965, the first prototype was lost during a test flight, killing Hamburger Flugzeugbau's chief test pilot; several design changes were made to change the Hansa Jet's stall characteristics. Type certification of the Hansa Jet was received during early 1967 and the first deliveries commenced during the following year. The largest customer of the type was the German Air Force , who tasked it with both training and VIP transport duties. During 1973, it was decided to end production of the Hansa Jet. Reasons for the programme's termination include increased competition from newer executive jets, a decline in the value of the US dollar, and the limited sales of the type. The German Air Force continued to operate their Hansa Jets into the early 1990s. A limited number continued to be used amongst civilian operators into the 21st century.
  • 2.7K
  • 27 Oct 2022
Topic Review
Waste Plastic Thermal Pyrolysis
Pyrolysis is one of the most popular thermo-chemical treatment (TCT) methods known today. This is due to their immense impacts on the environment and their operational output. The significant role of pyrolysis with waste plastics as feedstock is trending. Most of these waste plastics which include high-density polyethylene (HDPE), low-density polyethylene (LDPE), polyethylene terephthalate (PET) and polystyrene (PS), have continued to render our environment, our health and oceans in deplorable conditions. This entry presents an assurance into the current findings of waste plastic thermal pyrolysis (WPTP) and revealed some common research gaps and misconceptions surrounding this field. 
  • 2.7K
  • 04 Mar 2022
Topic Review
Municipal Solid Waste Management
Municipal Solid Waste (MSW) management has been a major problem of modern cities for many years. Thus, the development of optimal waste management strategies has been a priority for the European Commission, especially in the transition toward a circular economy. Efficient waste streams sorting is of vital importance for the effective implementation of an integrated waste management system toward the sustainable management of MSW.
  • 2.7K
  • 26 Oct 2020
Topic Review
Preparation Methods for Large-Area Perovskite Solar Cells
Solar energy is one of the most encouraging, abundant, green, and renewable sources for decreasing or even replacing traditional energy in the future. The energy provided by the sun in one hour is sufficient to supply the Earth’s needs for an entire year. The recent rapid development in perovskite solar cells (PSCs) has led to significant research interest due to their notable photovoltaic performance, currently exceeding 25% power conversion efficiency for small-area PSCs. The materials used to fabricate PSCs dominate the current photovoltaic market, especially with the rapid increase in efficiency and performance.
  • 2.7K
  • 12 Apr 2022
Topic Review
Lunar Orbital Platform – Gateway
The Lunar Orbital Platform – Gateway (LOP-G) is a future space station in lunar orbit intended to serve as a solar-powered communications hub, science laboratory, short-term habitation module, and holding area for rovers and other robots. While the project is led by NASA, the Gateway is meant to be developed, serviced, and utilized in collaboration with commercial and international partners. It will serve as the staging point for robotic and crewed exploration of the lunar south pole, and is the proposed staging point for NASA's Deep Space Transport concept. The science disciplines to be studied on the Gateway are expected to include planetary science, astrophysics, Earth observations, heliophysics, fundamental space biology, and human health and performance. Under current plans, this scientific activity will start after the first crewed landing (Artemis 3). Gateway development includes all of the International Space Station partners: ESA, NASA, Roscosmos, JAXA, and CSA. Construction is planned to take place in the 2020s. The International Space Exploration Coordination Group (ISECG), which is composed of 14 space agencies including NASA, has concluded that LOP-G will be critical in expanding a human presence to the Moon, Mars, and deeper into the Solar System. Formerly known as the Deep Space Gateway, the station was renamed in NASA's 2018 proposal for the 2019 United States federal budget. When the budgeting process was complete, US$450 million had been committed by Congress to preliminary studies.
  • 2.7K
  • 26 Oct 2022
Topic Review
Corsac Fox
The Corsac Fox (Vulpes corsac) is a small wild canid species native to the steppes and semi-arid regions of Central Asia. Renowned for its distinctive sandy to pale gray fur and black-tipped tail, the Corsac Fox is well-adapted to its harsh desert environment. As an omnivorous opportunist, it preys on small mammals, birds, insects, and vegetation, exhibiting a versatile diet that allows it to thrive in diverse habitats.
  • 2.7K
  • 28 Feb 2024
Topic Review
Arsenic Induced Neurotoxicity
Arsenic is a ubiquitous environmental contaminant widely distributed in the surrounding environmental compartments. Exposure to inorganic arsenic is known to cause major neurological effects such as cytotoxicity, chromosomal aberration, damage to cellular DNA and genotoxicity. On the other hand, long-term exposure to arsenic may cause neurobehavioral effects in the juvenile stage, which may have detrimental effects in the later stages of life. Thus, it is important to understand the toxicology and underlying molecular mechanism of arsenic which will help to mitigate its detrimental effects.
  • 2.6K
  • 11 Mar 2022
Topic Review
Applications of Zinc Oxide Nanoparticles in Food/Agriculture
Zinc oxide nanoparticles (ZnO-NPs) have gained significant interest in the agricultural and food industry as a means of killing or reducing the activity of microorganisms. The antibacterial properties of ZnO-NPs may improve food quality, which has a direct impact on human health. ZnO-NPs are one of the most investigated inorganic nanoparticles and have been used in various related sectors, with the potential to rapidly gain attention and increase interest in the agriculture and food industries. 
  • 2.6K
  • 20 Apr 2023
Topic Review
DNA Methylation in Leukemia, Myelodysplastic Syndrome, and Lymphoma
DNA methylation represents a crucial mechanism of epigenetic regulation in hematologic malignancies. The methylation process is controlled by specific DNA methyl transferases and other regulators, which are often affected by genetic alterations. Global hypomethylation and hypermethylation of tumor suppressor genes are associated with hematologic cancer development and progression. Several epi-drugs have been successfully implicated in the treatment of hematologic malignancies, including the hypomethylating agents (HMAs) decitabine and azacytidine. However, combinations with other treatment modalities and the discovery of new molecules are still the subject of research to increase sensitivity to anti-cancer therapies and improve patient outcomes. 
  • 2.6K
  • 09 Apr 2024
Topic Review
Chemically Modified Starches as Food Additives
Starch is a renewable and multifunctional polysaccharide biopolymer that is widely used both in the food industry and other areas of the economy. However, due to a number of undesirable properties in technological processes, it is subjected to various modifications. They improve its functional properties and enable the starch to be widely used in various industries. A modified starch is a natural starch that has been treated in a way that changes one or more of its initial physical and/or chemical properties. Chemical modification consists of the introduction of functional groups into starch molecules, which result in specific changes in the physicochemical and functional properties of starch preparations. The bases of chemical modifications of starch are oxidation, esterification or etherification reactions. In terms of functionality, modified preparations include cross-linked and stabilized starches. These starches have the status of allowed food additives, and their use is strictly regulated by relevant laws. Large-scale scientific research is aimed at developing new methods of starch modification, and the use of innovative technological solutions allows for an increasingly wider use of such preparations.
  • 2.6K
  • 28 Nov 2023
Topic Review
17O in Hydrological Cycle
17O is the one of the naturally occurring stable isotopes of oxygen, and also it has the lowest abundance, 0.038%(). The distribution of isotopes in hydrological systems is controlled by isotope fractionation processes. Oxygen isotopes fractionate through mass-dependent isotopic fractionation, which includes kinetic processes, isotopic exchange reactions, and physicochemical phenomena (diffusion, condensation, and evaporation).
  • 2.6K
  • 03 Aug 2021
Topic Review
Red Macroalgae
Red Seaweed “Rhodophyta” are an important group of macroalgae that include approximately 7000 species. They are a rich source of structurally diverse bioactive constituents, including protein, sulfated polysaccharides, pigments, polyunsaturated fatty acids, vitamins, minerals, and phenolic compounds with nutritional, medical, and industrial importance. Polysaccharides are the main components in the cell wall of red algae and represent about 40–50% of the dry weight, which are extensively utilized in industry and pharmaceutical compounds, due to their thickening and gelling properties. The hydrocolloids galactans carrageenans and agars are the main red seaweed cell wall polysaccharides, which had broad-spectrum therapeutic characters. Generally, the chemical contents of seaweed are different according to the algal species, growth stage, environment, and external conditions, e.g., the temperature of the water, light intensity, nutrient concentrations in the ecosystem. Economically, they can be recommended as a substitute source for natural ingredients that contribute to a broad range of bioactivities like cancer therapy, anti-inflammatory agents, and acetylcholinesterase inhibitory. This entry touches on the mainpoints of the pharmaceutical applications of red seaweed, as well as the exploitation of their specific compounds and secondary metabolites with vital roles.
  • 2.6K
  • 07 Dec 2020
Topic Review
Graphene Quantum Dots
Graphene quantum dots (GQD) is an efficient nanomaterial composed of one or more layers of graphene with unique properties that combine both graphene and carbon dots (CDs). It can be synthesized using carbon-rich materials as precursors, such as graphite, macromolecules polysaccharides, and fullerene. This contribution emphasizes the utilization of GQD-based materials in the fields of sensing, bioimaging, energy storage, and corrosion inhibitors. Inspired by these numerous applications, various synthetic approaches have been developed to design and fabricate GQD, particularly bottom-up and top-down processes. 
  • 2.6K
  • 06 Apr 2021
Topic Review
Biomethanation Facilities in Europe
In line with the long-term strategy of the European Union to become climate-neutral, the energy storage challenge that is induced by volatile renewable electricity production (e.g., with rapidly growing photovoltaic capacities) must be handled. The power-to-methane technology is promising for long-term, high-capacity energy storage. Currently, there are two different industrial-scale methanation methods: the chemical one (based on the Sabatier reaction) and the biological one (using microorganisms for the conversion). The second method can be used not only to methanize the mixture of pure hydrogen and carbon dioxide but also to methanize the hydrogen and carbon dioxide content of low-quality gases, such as biogas or deponia gas, enriching them to natural gas quality; therefore, the applicability of biomethanation is very wide.
  • 2.6K
  • 08 Oct 2021
Topic Review
Psychographic Segmentation
Psychographic segmentation has been used in marketing research as a form of market segmentation which divides consumers into sub-groups based on shared psychological characteristics, including subconscious or conscious beliefs, motivations, and priorities to explain and predict consumer behavior. Developed in the 1970´s, it applies behavioral and social sciences to explore to understand consumers’ decision-making processes, consumer attitudes, values, personalities, lifestyles, and communication preferences. It complements demographic and socioeconomic segmentation, and enables marketers to target audiences with messaging to market brands, products or services. Some consider lifestyle segmentation to be interchangeable with psychographic segmentation, marketing experts argue that lifestyle relates specifically to overt behaviors while psychographics relate to consumers' cognitive style, which is based on their "patterns of thinking, feeling and perceiving".
  • 2.6K
  • 09 Nov 2022
Topic Review
Biological Barriers to Oral Drug Delivery Systems
The oral route is the most preferred route for systemic and local drug delivery. However, the oral drug delivery system faces the harsh physiological and physicochemical environment of the gastrointestinal tract, which limits the bioavailability and targeted design of oral drug delivery system.
  • 2.6K
  • 08 Feb 2023
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