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Topic Review Peer Reviewed
Frederick III of Aragon (1296–1337)
Frederick III of Aragon, King of Sicily (1296–1337). Frederick III of Aragon was the third king of the Aragonese dynasty on the throne of Sicily. He ruled from 1296 to 1337 and he was the only Aragonese king of Sicily who made a significant use of his image. In particular, we have four official (namely, commissioned directly by him or his entourage) representations of him: the royal seal, the billon silver denaro coin, the lost mosaic from the Church of Santa Maria della Valle (known as Badiazza) near Messina, and the mosaic in the Cathedral of Messina.
  • 4.6K
  • 13 Apr 2022
Topic Review
GTK+
GTK+ (formerly GIMP Toolkit) is a cross-platform widget toolkit for creating graphical user interfaces. It is licensed under the terms of the GNU Lesser General Public License, allowing both free and proprietary software to use it. It is, along with Qt, one of the most popular tool-kits for the Wayland and X11 windowing systems.
  • 4.6K
  • 10 Nov 2022
Topic Review
Education of Midwives in Portugal and Spain
In Europe, midwives education, in accordance with the principles of the Bologna Declaration, are based on the pillars defined by Directive 2005/36/CE and by the Munich Declaration. In Portugal, the candidate applies on their own initiative to one of the Higher Education Institutions (HEIs) that provide such training. At the end of the education, students will achieve the master title. In Spain, the candidate sits for a state exam, which is announced annually by each autonomous community, for admission to the specialization.
  • 4.6K
  • 24 Jun 2022
Topic Review
Seed Priming
Seed nano-priming is an efficient process that can change seed metabolism and signaling pathways, affecting not only germination and seedling establishment but also the entire plant lifecycle.
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  • 13 Jan 2022
Topic Review
History of X-ray Research in Colonial India
This is the stroy of the beginning of X-ray research in colonial India and its progress to understand the India's respectable position globally in X-ray researh in modern times.The history of X-ray research in colonial India started with the procurement of X-ray tube by Dr. Mahendralal Sircar within six months of the discovery of X-rays at the Indian Association for the Cultivation of Science (IACS). The first application of X-rays for clinical purposes was done, in private capacity, independently by Dr. Sircar and Sir J.C. Bose. After his return from England in 1921, C.V. Raman initiated serious X-ray scattering studies in the structure of matter at the IACS which proliferated to all parts of India and laid the foundation stone of modern X-ray research in India.
  • 4.6K
  • 29 Jun 2022
Topic Review
Cytokines in Inflammatory Disease
This review aims to briefly discuss a short list of a broad variety of inflammatory cytokines. Numerous studies have implicated that inflammatory cytokines exert important effects with regard to various inflammatory diseases, yet the reports on their specific roles are not always consistent. They can be used as biomarkers to indicate or monitor disease or its progress, and also may serve as clinically applicable parameters for therapies. Yet, their precise role is not always clearly defined. Thus, in this entry, researchers focus on the existing literature dealing with the biology of cytokines interleukin (IL)-6, IL-1, IL-33, tumor necrosis factor-alpha (TNF-α), IL-10, and IL-8. We will briefly focus on the correlations and role of these inflammatory mediators in the genesis of various inflammatory impacts.
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  • 13 Oct 2021
Topic Review
Spray Drying for Oils Encapsulation
This is a entry focused on the application of spray drying technology for the edible oils encapsulation. This entry covered most of the relevant works have done recently on the encapsulation of oils by spray drying. The factors affecting the process of encapsulation and the application in food with the properties of the final product.The application of the spray drying technique in the food industry for the production of a broad range of ingredients has become highly desirable compared to other drying techniques. Recently, the spray drying technique has been applied extensively for the production of functional foods, pharmaceuticals and nutraceuticals. Encapsulation using spray drying is highly preferred due to economic advantages compared to other encapsulation methods. Encapsulation of oils using the spray drying technique is carried out in order to enhance the handling properties of the products and to improve oxidation stability by protecting the bioactive compounds. Encapsulation of oils involves several parameters—including inlet and outlet temperatures, total solids, and the type of wall materials—that significantly affect the quality of final product.
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  • 19 Apr 2022
Topic Review
Microemulsion Design for Acne Therapy
Acne represents a dermatologic condition with a high prevalence, being characterized by a complex pathogenesis. Its high recurrence frequently encountered in clinical practice will affect the patient’s quality of life. Most of the treatment algorithms require at least one topical formulation, being recommended to be applied on affected areas for a long period. To treat such a versatile skin condition, smart topical vehicles capable of entrap anti-acne compounds can be considered a good option, compared with conventional systems generally used at the moment. In this direction, microemulsions are appreciated for their superior profile in matters of drug delivery, especially for challenging substances with hydrophilic or lipophilic patterns. Designed as transparent and thermodynamically stable systems, with a small number of key ingredients, microemulsion-based formulations were characterized in the present review as unique structures able to pass the skin barrier and sustain a targeted therapy in acne pathology.
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  • 30 Nov 2020
Topic Review
Adaptation
The term “adaptation” is currently used in the climate field. It originated from natural science in the field of population biology and evolutionary ecology. It originally referred to the general characteristics that ensure the survival and reproduction of organic individuals in living environments. The definition of “adaptation” has many attributes, including the two most important points. First is the spatial scale of adaptation, which depends on who is responsible. Second is the nature of adaptive behavior, whether it is spontaneous or conscious or it is planned or prescriptive. The former is usually short-term and tactical adaptation, which is directly related to specific climate change. The latter is more strategic, long-term, and proactive and is usually formulated by government departments and used as part of policy adaptation measures. The adaptation to climate change in the literature is sometimes divergent at the temporal and spatial scales. Short-term adaptation is more of a reaction, and higher-scale adaptation is considered an expected adaptation through policies, projects, and recent plans and actions.
  • 4.6K
  • 15 Nov 2021
Topic Review
Cry Proteins in Biotechnology
A hallmark of Bacillus thuringiensis bacteria is the formation of one or more parasporal crystal (Cry) proteins during sporulation. The toxicity of these proteins is highly specific to insect larvae, exerting lethal effects in different insect species but not in humans or other mammals. In 1989, a nomenclature was proposed to classify proteins according to their sequence and specificity. In this initial nomenclature, there were only four classes. The first class included proteins with action against Lepidoptera with a size of approximately 130–140 kDa. The second class included smaller proteins (65 kDa) with activity against Lepidoptera and Diptera; this class included only two members: CryIIA and CryIIB. The third class constituted the active toxin against Coleoptera, CryIIIA. The last class was Cry1A, the members of which were closely related: they were called Cry1Aa, Cry1Ab, and Cry1Ac.
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  • 01 Feb 2022
Topic Review
Lipid Peroxidation
Lipid peroxidation refers to the process in which lipids are oxidized to generate lipid peroxides as a primary product. Cellular lipid peroxidation can occur through different reactions, but they can be categorized into enzyme and non-enzyme dependent reactions. The primary substrates in lipid peroxidation reactions are polyunsaturated lipids since carbon-carbon double bonds are susceptible to reactive oxygen species, such as the hydroxyl radical (HO•), which is a key radical that participates in peroxidation reactions.
  • 4.6K
  • 14 Dec 2020
Topic Review
The Potent Phytoestrogen 8-Prenylnaringenin
8-prenylnaringenin (8-PN) is a prenylated flavonoid, occurring, in particular, in hop, but also in other plants. It has proven to be one of the most potent phytoestrogens in vitro known to date, and in the past 20 years, research has unveiled new effects triggered by it in biological systems. These findings have aroused the hopes, expectations, and enthusiasm of a “wonder-drug” for a host of human diseases. However, the majority of 8-PN effects require such high concentrations that they cannot be reached by normal dietary exposure, only pharmacologically; thus, adverse impacts may also emerge.
  • 4.6K
  • 01 Apr 2022
Topic Review
Language Attrition
Language attrition is the loss of a first or second language or a portion of that language by either a community or an individual. Language attrition is related to multilingualism and language acquisition. Many factors are at play in learning (acquisition) and unlearning (loss) the first and second languages. This can be a simple reversal of learning. In other cases, the type and speed of attrition depends on the individual, also on his or her age and skill level. For the same second language, attrition has been affected differently depending on what is the dominant first language environment. In many cases, attrition could well be case-by-case. Those language learners motivated to keep their first and second languages may very well maintain it, although to do so will likely involve continuous study, or regular use of both.
  • 4.6K
  • 01 Dec 2022
Topic Review
Snow Line
The climatic snow line is the boundary between a snow-covered and snow-free surface. The actual snow line may adjust seasonally, and be either significantly higher in elevation, or lower. The permanent snow line is the level above which snow will lie all year.
  • 4.6K
  • 16 Dec 2022
Topic Review Peer Reviewed
Microchip Electrophoresis
Microchip electrophoresis (MCE) is a miniaturized form of capillary electrophoresis. Electrophoresis is a common technique to separate macromolecules such as nucleic acids (DNA, RNA) and proteins. This technique has become a routine method for DNA size fragmenting and separating protein mixtures in most laboratories around the world. The application of higher voltages in MCE achieves faster and efficient electrophoretic separations. 
  • 4.6K
  • 13 Apr 2022
Topic Review
Parabolic Aluminized Reflector Light
A parabolic aluminized reflector lamp (also PARCAN light, PARcan, or simply PAR) is a type of electric lamp that is widely used in commercial, residential, and transportation illumination. Usage includes locomotive headlamps, aircraft landing lights, and residential and commercial recessed lights ("cans" in the United States). They are identical in principle to sealed beam automobile headlights. The lamps and their fixtures are widely used in theatre, concerts and motion picture production when a substantial amount of flat lighting is required for a scene. In situations where sunlight or other specular light is available, a white foam reflector is often used to accomplish the same effect as a PAR array. PAR cans are being replaced in some stage applications by LED PAR cans, which use less electric power and produce a wide array of saturated colors without the use of color filters, when white light is not needed.
  • 4.6K
  • 18 Oct 2022
Topic Review
Tropical Rainforest Climate
File:Koppen-Geiger Map Af present.svgA tropical rainforest climate is a tropical climate usually found within 10 to 15 degrees latitude of the equator, and has at least 60 millimetres (2.4 in) of rainfall every month of the year. Regions with this climate are typically designated Af by the Köppen climate classification. A tropical rainforest climate is typically hot, very humid, and wet.
  • 4.6K
  • 31 Oct 2022
Topic Review
Implementation of Food Safety Management
The food industry’s failure in planning and designing of and in implementing a Food Safety Management System and its foundation elements leads, in most instances, to compromised food safety and subsequent foodborne illness outbreaks. This phenomenon was noticed, worldwide, for all food processors, but with a much higher incidence in the medium- and small-sized food processing plants. Our study focuses on the importance of Food Safety Management System (FSMS), Critical Control Points Hazard Analysis (HACCP) and the Prerequisite Programs (PRPs) as the foundation of HACCP, in preventing foodborne outbreaks.
  • 4.6K
  • 27 Sep 2021
Topic Review
Epithelioid Cell
According to a common point of view Epithelioid cells (also called Epithelioid histiocytes) are derivatives of activated macrophages resembling epithelial cells.
  • 4.6K
  • 04 Nov 2022
Topic Review
Comparison Between Esperanto and Interlingua
Esperanto and Interlingua are two planned languages which have taken radically different approaches to the problem of providing an International auxiliary language (IAL). Although they are both classed as IALs, the intellectual bases of Esperanto and Interlingua are quite different. It has been argued that each language is a successful implementation of a particular IAL model. However, in both language communities there is a polemical tradition of using external criteria to critique the perceived opponent language (that is, judging Interlingua by Esperantist criteria and vice versa). In practical use, moreover, language usage in the two communities has sometimes shown convergences despite divergent theory.
  • 4.6K
  • 18 Oct 2022
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