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Topic Review
A Message from Earth (2008)
A Message from Earth (AMFE) is a high-powered digital radio signal that was sent on 9 October 2008 towards Gliese 581c, a large terrestrial extrasolar planet orbiting within the Gliese 581 system. The signal is a digital time capsule containing 501 messages that were selected through a competition on the social networking site Bebo. The message was sent using the RT-70 radar telescope. The signal will reach the planet Gliese 581c in early 2029. More than half a million people including celebrities and politicians participated in the AMFE project, which was the world's first digital time capsule where the content was selected by the public. As of 1 February 2018, the message has traveled 62.43 trillion kilometers of the total 192 trillion kilometers, which is 33.5% of the distance to the Gliese 581 system. On 13 February 2015, scientists (including David Grinspoon, Seth Shostak, and David Brin) at an annual meeting of the American Association for the Advancement of Science, discussed Active SETI and whether transmitting a message to possible intelligent extraterrestrials in the Cosmos was a good idea; That same week, a statement was released, signed by many in the SETI community, that a "worldwide scientific, political and humanitarian discussion must occur before any message is sent". However neither Frank Drake, nor Seth Shostak signed this appeal. On 28 March 2015, a related essay with some different point of view was written by Seth Shostak and published in The New York Times .
  • 4.5K
  • 21 Oct 2022
Topic Review
Blood Pressure Sensors
In our unique transdisciplinary approach, we studied the fundamentals of blood pressure and examined its measuring modalities while focusing on their clinical use and sensing principles to identify material functionalities. Then, we carefully reviewed various categories of functional materials utilized in sensor building blocks allowing for comparative analysis of the performance of a wide range of materials throughout the sensor operational-life cycle. Not only this provides essential data to enhance the materials’ properties and optimize their performance, but also, it highlights new perspectives and provides suggestions to develop the next generation pressure sensors for clinical use.
  • 4.5K
  • 10 Apr 2021
Topic Review
Household Food Waste in Bangkok
Food waste (FW) is one of the world’s major crises in both developed and developing countries. Up to 1.3 billion tons of food across the globe is thrown away each year, accounting for one third of all food produced for human consumption and presenting tremendous social, economic, and environmental challenges. In Thailand, FW causes a significant problem when it comes to waste management, particularly in metropolitan areas. Studies conducted between 2005 and 2009 indicated that FW made up the greatest proportion of all waste collected in Bangkok at between 42% and 45%. This waste was generated in households and was usually thrown away into garbage bins, to be collected and buried in landfills by governmental and private sector companies.
  • 4.5K
  • 04 Aug 2021
Topic Review
History of X-ray Research in Colonial India
This is the stroy of the beginning of X-ray research in colonial India and its progress to understand the India's respectable position globally in X-ray researh in modern times.The history of X-ray research in colonial India started with the procurement of X-ray tube by Dr. Mahendralal Sircar within six months of the discovery of X-rays at the Indian Association for the Cultivation of Science (IACS). The first application of X-rays for clinical purposes was done, in private capacity, independently by Dr. Sircar and Sir J.C. Bose. After his return from England in 1921, C.V. Raman initiated serious X-ray scattering studies in the structure of matter at the IACS which proliferated to all parts of India and laid the foundation stone of modern X-ray research in India.
  • 4.5K
  • 29 Jun 2022
Topic Review
Transparent Solar Windows
Many modern glass and window products are based on metal-dielectric coatings, which can control properties such as thermal emissivity, heat gain, colour, and transparency. These can also enable solar energy harvesting through PV integration, if the glazing structure is purpose-designed, to include luminescent materials and special microstructures. Recently, significant progress has been demonstrated in building integrated transparent solar windows, which are expected to add momentum towards the development of smart cities. These window systems are, at present in 2019, the only type of transparent and clear construction materials capable of providing significant energy savings in buildings, simultaneously with renewable energy generation.
  • 4.5K
  • 09 Oct 2024
Topic Review
Type 69 RPG
The Type 69 85mm rocket propelled grenade (RPG), made by Norinco, is a Chinese variant of the Soviet RPG-7. First introduced in 1972, the Type 69 is a common individual anti-tank weapon in service with the PLA. More advanced grenade rounds were developed in the 1980s and 1990s to meet the requirements of modern battlefields. Eventually, the aging Type 69 RPG family was replaced by modern anti-tank weapon systems developed by China such as Type 89 and Type 08.
  • 4.5K
  • 08 Nov 2022
Topic Review
Halt and Catch Fire
In computer engineering, Halt and Catch Fire, known by the assembly mnemonic HCF, is an idiom referring to a computer machine code instruction that causes the computer's central processing unit (CPU) to cease meaningful operation, typically requiring a restart of the computer. It originally referred to a fictitious instruction in IBM System/360 computers, making a joke about its numerous non-obvious instruction mnemonics. With the advent of the MC6800, a design flaw was discovered by the programmers. Due to incomplete opcode decoding, two illegal opcodes, 0x9D and 0xDD, will cause the program counter on the processor to increment endlessly, which renders the processor useless. Those codes have been unofficially named HCF. During the design process of MC6802, engineers originally planned to remove this instruction, but kept it as-is for testing purposes. As a result, HCF was officially recognized as a real instruction. Later, HCF became a humorous catch-all term for instructions that may freeze a processor, including intentional instructions for testing purposes, and unintentional illegal instructions. Some are considered hardware defects, and if the system is shared, a malicious user can execute it to launch a denial-of-service attack. In the case of real instructions, the implication of this expression is that, whereas in most cases in which a CPU executes an unintended instruction (a bug in the code) the computer may still be able to recover, in the case of an HCF instruction there is, by definition, no way for the system to recover without a restart. The expression "catch fire" is a facetious exaggeration of the speed with which the CPU chip would be switching some bus circuits, causing them to overheat and burn.
  • 4.5K
  • 04 Nov 2022
Topic Review
Distributed Machine Learning in Edge Computing
Distributed edge intelligence is a disruptive research area that enables the execution of machine learning and deep learning (ML/DL) algorithms close to where data are generated. Since edge devices are more limited and heterogeneous than typical cloud devices, many hindrances have to be overcome to fully extract the potential benefits of such an approach (such as data-in-motion analytics).
  • 4.5K
  • 20 Apr 2022
Topic Review
Interleukin-2 and Interleukin-15
The immune system is a complex network dedicated to protecting an organism against harmful substances, including the eradication of invading pathogens or malignant cells, maintenance of specific memory lymphocytes and elimination of autoreactive immune cells to yield self-tolerances. Homeostasis of immune systems relies on two main components—the innate and adaptive immune responses, which are regulated by a series of cytokines that are released in response to certain stimulus. One of the most extensively studied cytokines is the common cytokine receptor common gamma chain (γc) family of cytokines, including interleukin-2 (IL-2), IL-4, IL-7, IL-9, IL-15 and IL-21, which is named based on the usage of γc subunit for their receptors. This set of cytokines display broad pleiotropic actions to regulate both the innate and adaptive immune system, collectively contributing to the development of various immune cell populations, modulating cell differentiation, and either promoting the survival or inducing the apoptosis depending on the cellular context.
  • 4.5K
  • 08 Feb 2021
Topic Review
Cry Proteins in Biotechnology
A hallmark of Bacillus thuringiensis bacteria is the formation of one or more parasporal crystal (Cry) proteins during sporulation. The toxicity of these proteins is highly specific to insect larvae, exerting lethal effects in different insect species but not in humans or other mammals. In 1989, a nomenclature was proposed to classify proteins according to their sequence and specificity. In this initial nomenclature, there were only four classes. The first class included proteins with action against Lepidoptera with a size of approximately 130–140 kDa. The second class included smaller proteins (65 kDa) with activity against Lepidoptera and Diptera; this class included only two members: CryIIA and CryIIB. The third class constituted the active toxin against Coleoptera, CryIIIA. The last class was Cry1A, the members of which were closely related: they were called Cry1Aa, Cry1Ab, and Cry1Ac.
  • 4.5K
  • 01 Feb 2022
Topic Review
Tropical Rainforest Climate
File:Koppen-Geiger Map Af present.svgA tropical rainforest climate is a tropical climate usually found within 10 to 15 degrees latitude of the equator, and has at least 60 millimetres (2.4 in) of rainfall every month of the year. Regions with this climate are typically designated Af by the Köppen climate classification. A tropical rainforest climate is typically hot, very humid, and wet.
  • 4.5K
  • 31 Oct 2022
Topic Review
Comparison Between Esperanto and Interlingua
Esperanto and Interlingua are two planned languages which have taken radically different approaches to the problem of providing an International auxiliary language (IAL). Although they are both classed as IALs, the intellectual bases of Esperanto and Interlingua are quite different. It has been argued that each language is a successful implementation of a particular IAL model. However, in both language communities there is a polemical tradition of using external criteria to critique the perceived opponent language (that is, judging Interlingua by Esperantist criteria and vice versa). In practical use, moreover, language usage in the two communities has sometimes shown convergences despite divergent theory.
  • 4.5K
  • 18 Oct 2022
Topic Review
Human Factors and Road Traffic Safety
Human factors play a huge role in road traffic safety. Research has found that a huge proportion of traffic crashes occur due to some form of human error. Improving road user behavior has been the major strategy that has been emphasized for improving road traffic safety. Meanwhile, despite the training efforts, and testing for drivers, the global status of road traffic safety is alarming.
  • 4.5K
  • 02 Feb 2024
Topic Review Peer Reviewed
Microchip Electrophoresis
Microchip electrophoresis (MCE) is a miniaturized form of capillary electrophoresis. Electrophoresis is a common technique to separate macromolecules such as nucleic acids (DNA, RNA) and proteins. This technique has become a routine method for DNA size fragmenting and separating protein mixtures in most laboratories around the world. The application of higher voltages in MCE achieves faster and efficient electrophoretic separations. 
  • 4.5K
  • 13 Apr 2022
Topic Review
Fat Leonard Scandal
The Fat Leonard scandal is a corruption scandal and ongoing investigation within the United States Navy involving ship support contractor Glenn Defense Marine Asia (GDMA), a subsidiary of the Glenn Marine Group. The Washington Post called the scandal "perhaps the worst national-security breach of its kind to hit the Navy since the end of the Cold War." At the heart of the scandal was Glenn Defense Marine Asia, a firm run by Leonard Glenn Francis, a Malaysian national known as "Fat Leonard" for his then over 350 pound weight. Francis provided at least a half million dollars in cash, plus travel expenses, luxury items, and prostitutes to a large number of U.S. uniformed officers of the United States Seventh Fleet, who in turn gave him classified material about the movements of U.S. ships and submarines, confidential contracting information, and information about active law enforcement investigations into Glenn Defense Marine Asia. Francis then "exploited the intelligence for illicit profit, brazenly ordering his moles to redirect aircraft carriers to ports he controlled in Southeast Asia so he could more easily bilk the Navy for fuel, tugboats, barges, food, water and sewage removal." The Navy, through GDMA, even employed divers to search harbors for explosives. He also directed them to author "Bravo Zulu" memos, which is an informal term for a letter of commendation from the Navy given to civilians who have performed outstanding services for the Navy, in order to bolster GDMA's credibility for jobs "well done". The first activities of the conspiracy were confirmed to have existed in 2006 when Francis recruited numerous Navy personnel to engage in corruption, including directing contracts toward his firm, disfavoring competitors, and inhibiting legitimate fiscal and operational oversight. The initial co-conspirators labelled themselves "the cool kids" and "the wolf pack." U.S. federal prosecutors filed criminal charges against 33 people in connection with the Fat Leonard scandal. Of those, 22 pleaded guilty: Francis himself, four of his top aides, and 17 Navy officials (specifically, at least ten commissioned officers, two petty officers, one former NCIS special agent, and two civilian Navy contracting officials). Nine others are awaiting trial in U.S. district court in San Diego. Separately, five Navy officers were charged with crimes under the Uniform Code of Military Justice (UCMJ) and have been subject to court-martial proceedings. An additional civilian pleaded guilty to a scandal-related crime in Singapore court. Suffering health problems, Francis was hospitalized and released in March 2018. Rather than returning to the custody of the U.S. Marshals Service, he was granted a medical furlough and allowed to stay in San Diego at a private residence owned by one of his physicians, under 24-hour surveillance for which his family paid. At a deposition taken in 2018 in the David A. Morales case, Francis said he is being treated for kidney cancer. In 1989, when he was 21, Francis had been sentenced to three years in jail in Malaysia for firearms possession.
  • 4.5K
  • 14 Oct 2022
Topic Review
Epoxides Cycloaddition for CO2 Utilization
In the present review (10.3390/pr8050548), CO2 cycloaddition can be seen as a reasonably competent alternative to CO2 transformation, offsetting the high value-added nature by extending material use defer CO2 back to the atmosphere when compared to commodities and fuels such as urea, methanol, and methane.
  • 4.5K
  • 27 Aug 2020
Topic Review
Reclaimed Water
Reclaimed or recycled water (also called wastewater reuse or water reclamation) is the process of converting wastewater into water that can be reused for other purposes. Reuse may include irrigation of gardens and agricultural fields or replenishing surface water and groundwater (i.e., groundwater recharge). Reused water may also be directed toward fulfilling certain needs in residences (e.g. toilet flushing), businesses, and industry, and could even be treated to reach drinking water standards. This last option is called either "direct potable reuse" or "indirect potable" reuse, depending on the approach used. Reclaiming water for reuse applications instead of using freshwater supplies can be a water-saving measure. When used water is eventually discharged back into natural water sources, it can still have benefits to ecosystems, improving streamflow, nourishing plant life and recharging aquifers, as part of the natural water cycle. Wastewater reuse is a long-established practice used for irrigation, especially in arid countries. Reusing wastewater as part of sustainable water management allows water to remain as an alternative water source for human activities. This can reduce scarcity and alleviate pressures on groundwater and other natural water bodies.
  • 4.5K
  • 24 Oct 2022
Topic Review
Cytokines in Inflammatory Disease
This review aims to briefly discuss a short list of a broad variety of inflammatory cytokines. Numerous studies have implicated that inflammatory cytokines exert important effects with regard to various inflammatory diseases, yet the reports on their specific roles are not always consistent. They can be used as biomarkers to indicate or monitor disease or its progress, and also may serve as clinically applicable parameters for therapies. Yet, their precise role is not always clearly defined. Thus, in this entry, researchers focus on the existing literature dealing with the biology of cytokines interleukin (IL)-6, IL-1, IL-33, tumor necrosis factor-alpha (TNF-α), IL-10, and IL-8. We will briefly focus on the correlations and role of these inflammatory mediators in the genesis of various inflammatory impacts.
  • 4.5K
  • 13 Oct 2021
Topic Review
Lipids in Food Flavor Generation
Lipids in food are a source of essential fatty acids and also play a crucial role in flavor and off-flavor development. Lipids contribute to food flavor generation due to their degradation to volatile compounds during food processing, heating/cooking, and storage and/or interactions with other constituents developed from the Maillard reaction and Strecker degradation, among others. The degradation of lipids mainly occurs via autoxidation, photooxidation, and enzymatic oxidation, which produce a myriad of volatile compounds. The oxidation of unsaturated fatty acids generates hydroperoxides that then further break down to odor-active volatile secondary lipid oxidation products including aldehydes, alcohols, and ketones.
  • 4.5K
  • 15 Aug 2022
Topic Review
Dromomania
Dromomania was a historical psychiatric diagnosis whose primary symptom was uncontrollable urge to walk or wander. Dromomania has also been referred to as travelling fugue. Non-clinically, the term has come to be used to describe a desire for frequent traveling or wanderlust.
  • 4.5K
  • 01 Nov 2022
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