| Version | Summary | Created by | Modification | Content Size | Created at | Operation |
|---|---|---|---|---|---|---|
| 1 | Vivi Li | -- | 6346 | 2022-10-21 01:43:04 |
A controversy surrounding the combined measles, mumps, and rubella (MMR) vaccine started with the 1998 publication of a fraudulent research paper in The Lancet linking the vaccine to colitis and autism spectrum disorders. The claims in the paper were widely reported, leading to a sharp drop in vaccination rates in the UK and Ireland and increases in the incidence of measles and mumps, resulting in deaths and serious permanent injuries. Following the initial claims in 1998, multiple large epidemiological studies were undertaken. Reviews of the evidence by the Centers for Disease Control and Prevention, the American Academy of Pediatrics, the Institute of Medicine of the US National Academy of Sciences, the UK National Health Service, and the Cochrane Library all found no link between the MMR vaccine and autism. An investigation by journalist Brian Deer found that Andrew Wakefield, the author of the original research paper linking the vaccine to autism, had multiple undeclared conflicts of interest, had manipulated evidence, and had broken other ethical codes. The Lancet paper was partially retracted in 2004 and fully retracted in 2010, when Lancet's editor-in-chief Richard Horton described it as "utterly false" and said that the journal had been deceived. Wakefield was found guilty by the General Medical Council of serious professional misconduct in May 2010 and was struck off the Medical Register, meaning he could no longer practise as a doctor in the UK. In 2011, Deer provided further information on Wakefield's improper research practices to the British Medical Journal, which in a signed editorial described the original paper as fraudulent. The scientific consensus is that there is no link between the MMR vaccine and autism and that the vaccine's benefits greatly outweigh its risks. Wakefield's paper was described as "perhaps, the most damaging medical hoax of the last 100 years". Physicians, medical journals, and editors have described Wakefield's actions as fraudulent and tied them to epidemics and deaths.