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Topic Review
Microalgae for Wastewater Treatment
The water resource crisis and concerns with environmental pollution prompt the necessity to upgrade conventional wastewater treatment processes. The microalgae-based wastewater treatment process has shown many advantages that can fulfill the stricter demands for improved wastewater treatment. Microalgae cultivation can be carried out in different photobioreactors and under different operational conditions. The cultivation of the microalgae biomass provides the bioremediation of some targeted pollutants through uptake/digestion or biosorption, resulting in treated effluent and the production of biomass.
  • 1.4K
  • 10 Apr 2023
Topic Review
6G-Enabled Smart Cities
The sixth-generation (6G) wireless communication is the successor of fifth-generation (5G) communication. From a technological point of view, it makes use of higher frequency radio bands and provides a higher capacity combined with lower latency, enabling the integration into a single network with increased throughput and reliability. These characteristics make 6G networks ideal for the large-scale adoption of the Internet of Things (IoT) paradigm, especially considering that, in a short time, the devices connected to the IoT infrastructure are expected to reach billions of devices.
  • 1.4K
  • 18 Sep 2023
Topic Review
Solar Hybrid Photovoltaic Thermal System
A Hybrid Photovoltaic Thermal (PVT) system is one of the most emerging and energy-efficient technologies in the area of solar energy engineering. Several cell technologies with spectrum analysis are discussed to understand the application’s ability and energy efficiency.
  • 1.4K
  • 07 Feb 2024
Topic Review
RFID Technology and Main Components
RFID Technology is an automatic identification technology, which works through radio signals, retrieving and storing data remotely. It is used in hundreds, or perhaps even thousands, of applications with the aim of collecting data about objects in order to identify ways to solve everyday problems.
  • 1.4K
  • 28 Feb 2024
Topic Review
April 18: Albert Einstein Passed Away
On April 18, 1955, the world lost one of its greatest intellectual giants. Albert Einstein, the Nobel Prize-winning physicist whose theories reshaped modern science, passed away in Princeton, New Jersey, at the age of 76. His death marked not only the conclusion of an extraordinary life but also a turning point in 20th-century scientific history. Though his voice was silenced, his ideas continue to resonate through the cosmos.
  • 1.4K
  • 17 Apr 2025
Topic Review
Built Environment for People with Sensory Disabilities
People with sensory disabilities constitute a significant portion of society whose accessibility needs must be prioritized in the design of the built environment. Sensory disabilities cause a gap in the environmental information received, most commonly visual and/or auditory cues, that requires consideration to create equal opportunities and experiences for all. 
  • 1.4K
  • 27 Mar 2024
Topic Review
Hidden-Measurements Interpretation
The hidden-measurements interpretation (HMI), also known as the hidden-measurements approach, is a realistic interpretation of quantum mechanics. The basis of the hidden-measurements interpretation (HMI) is the hypothesis that a quantum measurement involves a certain amount of unavoidable fluctuations in the way the measuring system interacts with the measured entity. As a consequence, the interaction is not a priori given in a quantum measurement, but is each time selected (that is, actualized, through a weighted symmetry breaking processes) when the experiment is executed; and since different measurement-interactions can produce different outcomes, this can explain why the output of a quantum measurement can only be predicted in probabilistic terms. (One should not think however of these hidden measurement-interactions to be something similar to, or to be describable in the same way as, the fundamental interactions (fundamental forces) of the standard model of particle physics, mediated by bosonic elementary entities).
  • 1.4K
  • 03 Nov 2022
Topic Review
Type-2 Diabetes Mellitus and Dementia
Dementia is reported to be common in those with type 2 diabetes mellitus. Type 2 diabetes contributes to common molecular mechanisms and an underlying pathology with dementia. Brain cells becoming resistant to insulin leads to elevated blood glucose levels, impaired synaptic plasticity, microglial overactivation, mitochondrial dysfunction, neuronal apoptosis, nutrient deprivation, TAU (Tubulin-Associated Unit) phosphorylation, and cholinergic dysfunction.
  • 1.4K
  • 30 Nov 2022
Topic Review
Corynebacterium Glutamicum Mechanosensing
Corynebacterium glutamicum is a workhorse for industrial amino acid production, and the most striking feature of this bacterium is L-glutamate secretion. L-glutamate secretion is triggered by altering cell surface structures by biotin limitation, adding surfactants, penicillin, etc. Mechanosensing by MscCG-type mechanosensitive channels is the central physiological phenomenon for the L-glutamate secretion, and understanding the structural and functional diversity of MscS bacterial mechanosensitive channel superfamily will solve long-puzzling questions in Corynebacterium glutamicum.
  • 1.4K
  • 25 Feb 2021
Topic Review
Roxadustat
Roxadustat is the first oral drug in the class of new erythropoiesis drugs and a potent HIF-PHD inhibitor, exerted to treat anemia in patients with CKD. In phase 1, 2 and 3 studies with CKD-affected patients, roxadustat was more effective to stimulate erythropoiesis for anemia correction than previously used drugs. Roxadustat can be orally given, unlike other erythropoiesis drugs with parenteral administration only, which grants roxadustat a considerable advantage.
  • 1.4K
  • 16 Mar 2021
Topic Review
Hydrogen Embrittlement of Medium-Mn Steels
Recent research efforts to develop advanced–/ultrahigh–strength medium-Mn steels have led to the development of a variety of alloying concepts, thermo-mechanical processing routes, and microstructural variants for these steel grades. However, certain grades of advanced–/ultrahigh–strength steels (A/UHSS) are known to be highly susceptible to hydrogen embrittlement, due to their high strength levels. Hydrogen embrittlement characteristics of medium–Mn steels are less understood compared to other classes of A/UHSS, such as high Mn twinning–induced plasticity steel, because of the relatively short history of the development of this steel class and the complex nature of multiphase, fine-grained microstructures that are present in medium–Mn steels. The motivation of this paper is to review the current understanding of the hydrogen embrittlement characteristics of medium or intermediate Mn (4 to 15 wt pct) multiphase steels and to address various alloying and processing strategies that are available to enhance the hydrogen-resistance of these steel grades.
  • 1.4K
  • 04 Nov 2021
Topic Review
Liposomal Cytarabine
Cancer is the second leading cause of death worldwide. The main modality to fight against cancer is surgery, radiotherapy, and chemotherapy, and more recently targeted therapy, gene therapy and immunotherapy, which play important roles in treating cancer patients. In the last decades, chemotherapy has been well developed. Nonetheless, administration of the drug is not always successful, as limited drug dosage can reach the tumor cells.. In this context, the possibility to use an encapsulated anti-cancer drug may potentially solve the problem. Liposomal cytarabine is a formulation with pronounced effectiveness in lymphomatous meningitis and reduced cardiotoxicity if compared to liposomal anthracyclines. Thus, the future liposomal cytarabine use could be extended to other diseases given its reduction in cytotoxic side effects compared to the free formulation. 
  • 1.4K
  • 22 Jul 2021
Topic Review
Acyclic Nucleic Acids with Phosphodiester Linkages
The pseudo-rotational flexibility of the ribonucleotide is considerably limited due to the anomeric effect, and RNA/RNA and RNA/DNA duplexes are generally more thermally stable than DNA/DNA duplexes. The rigidity of the cyclic scaffold has been considered important for the formation of thermally stable duplexes, and the unexpectedly high thermal stability of duplexes formed with the participation of LNA oligomers could serve as an excellent justification for this point of view. However, this generalization is not consistent with the behavior of Peptide Nucleic Acids (PNA), in which the heterocyclic bases are attached to a linear peptide-like backbone, since duplexes composed of RNA or DNA and PNA strands are far more stable than RNA/RNA and DNA/DNA ones. This phenomenon may be attributed to the absence of a negative charge in the backbone, such that the absence of repulsive interactions balances the entropic cost of proper spatial organization of the flexible PNA scaffolds. Nonetheless, the widely accepted importance of the cyclic sugar components for the stability of the duplexes could be questioned. There is another perspective that can be applied to the acyclic analogs of nucleic acids that is related to the origin of life. The synthetic efforts on acyclic analogs of nucleic acids and provides information on the most interesting features of selected classes of such compounds, are here described. The selection includes the following types of analogs: Flexible (FNA), Unlocked (UNA), Glycol (GNA), Butyl (BuNA), Threoninol (TNA) and Serinol Nucleic Acids (SNA). These classes of analogs are discussed in terms of their synthetic methods, the thermal stability of their homo- and hetero-duplexes and their applicability in biological and biochemical research and nanotechnology.
  • 1.4K
  • 10 Feb 2022
Topic Review
Nano-Dentistry
Dental biomaterials were improved by nanotechnology. It manufactures better materials or improves the existing ones and forms the basis of novel methods for disease diagnosis and prevention. Modern nanotechnology makes oral health care services more acceptable for patients. Nanotechnology is now important area of research, covering a broad range of applications in dentistry.
  • 1.4K
  • 23 Feb 2022
Topic Review
Matrix Metalloproteinases in Dental and Periodontal Tissues
Matrix metalloproteinases (MMPs) are significant proteases, of evident contribution in dental and periapical tissue development, health and disease processes, with promising potential for use as diagnostic and prognostic disease biomarkers. Continuing understanding of their role in pathogenesis and progress of different dental, periapical and periodontal lesions, as well as in dentine-pulp wound healing could be a keystone to future diagnostic and therapeutic regimens.
  • 1.4K
  • 25 Aug 2022
Topic Review
VR Serious Games and Negative Schizophrenia Symptoms
Schizophrenia is a chronic brain disorder that affects 1 in every 300 people worldwide. VR is an interesting tool that has started to be used in remediation therapies. Although it is typically used as an exposure technique for specific phobias, VR has been applied, with encouraging results, to the study and treatment of schizophrenia. It can offer the potential for a significant therapeutic benefit, since patients are more willing to enter challenging situations and experiment with alternative ways of responding.
  • 1.4K
  • 19 Sep 2022
Topic Review
DO-254
RTCA DO-254 / EUROCAE ED-80, Design Assurance Guidance for Airborne Electronic Hardware is a document providing guidance for the development of airborne electronic hardware, published by RTCA, Incorporated and EUROCAE. The DO-254/ED-80 standard was formally recognized by the FAA in 2005 via AC 20-152 as a means of compliance for the design assurance of electronic hardware in airborne systems. The guidance in this document is applicable, but not limited, to such electronic hardware items as The document classifies electronic hardware items into simple or complex categories. An item is simple "if a comprehensive combination of deterministic tests and analyses appropriate to the design assurance level can ensure correct functional performance under all foreseeable operating conditions with no anomalous behavior." Conversely, a complex item is one that cannot have correct functional performance ensured by tests and analyses alone; so, assurance must be accomplished by additional means. The body of DO-254/ED-80 establishes objectives and activities for the systematic design assurance of complex electronic hardware, generally presumed to be complex custom micro-coded components, as listed above. However, simple electronic hardware is within the scope of DO-254/ED-80 and applicants propose and use the guidance in this standard to obtain certification approval of simple custom micro-coded components, especially devices that support higher level (A/B) aircraft functions. The DO-254/ED-80 standard is the counterpart to the well-established software standard RTCA DO-178C/EUROCAE ED-12C. With DO-254/ED-80, the certification authorities have indicated that avionics equipment contains both hardware and software, and each is critical to safe operation of aircraft. There are five levels of compliance, A through E, which depend on the effect a failure of the hardware will have on the operation of the aircraft. Level A is the most stringent, defined as "catastrophic" effect (e.g., loss of the aircraft), while a failure of Level E hardware will not affect the safety of the aircraft. Meeting Level A compliance for complex electronic hardware requires a much higher level of verification and validation than Level E compliance.
  • 1.4K
  • 14 Oct 2022
Topic Review
Organizational Retaliatory Behavior
Organizational retaliatory behavior (ORB) is a form of workplace deviance. ORB is defined in the bottom up sense as an employee's reacting against a perceived injustice from their employer. ORB is also a top down issue occurring when an employee speaks out or acts in an unfavorable way against the employer. The International Journal of Conflict Management divides ORB into four different conceptual indicators: rule breaking, level or work behavior, affective commitment, and turnover intention. All of these are forms of workplace deviance.
  • 1.4K
  • 26 Oct 2022
Topic Review
AVIC UAVs
AVIC UAVs are Chinese UAVs developed by Aviation Industry Corporation of China (AVIC), some of which has entered service with Chinese military.
  • 1.4K
  • 02 Dec 2022
Biography
Peter Mittelstaedt
Peter Mittelstaedt pseudonym Karl Rottmann (born November 24, 1929 in Leipzig - November 21, 2014 in Erftstadt), was a German physicist, philosopher, and scientific theorist.[1][2][3] After studying physics at the universities of Jena, Bonn, and Göttingen, with a doctorate in theoretical physics in Göttingen in 1956 with Werner Heisenberg, Mittelstaedt had research stays at CERN in Geneva a
  • 1.4K
  • 16 Dec 2022
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