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Topic Review
Biography
Topic Review
Bacillus amyloliquefaciens
Bacillus amyloliquefaciens, a Gram-positive bacterium, has emerged as a versatile microorganism with significant applications in various fields, including industry, medicine, and agriculture.
450
16 Nov 2023
Topic Review
Cutibacterium acnes
Dysbiosis
This research presents the virulence factors, clinical relevance, and current treatments of C. acnes, highlighting its association with AV, post-surgical infections, and other diseases. It also explores alternative innovative therapies such as phage therapy in development/research that are gaining prominence, with a growing focus on personalized medical approaches.
342
17 Nov 2023
Topic Review
Epimedium
Flavonoids
Epimedium is a classical Chinese herbal medicine, which has been used extensively to treat various diseases, such as sexual dysfunction, osteoporosis, cancer, rheumatoid arthritis, and brain diseases. Flavonoids, such as icariin, baohuoside I, icaritin, and epimedin C, are the main active ingredients with diverse pharmacological activities.
521
23 Oct 2023
Topic Review
Helichrysum arenarium
Helichrysum arenarium (L.) Moench, belonging to the Asteraceae family, is known in traditional medicine for its diuretic, choleretic, and anti-inflammatory properties. Helichrysum arenarium (sandy everlasting) is a source of active pharmacological compounds used in complementary medicine to prevent digestive and hepatobiliary illnesses.
2.0K
21 Oct 2022
Topic Review
Komagataella
phaffii
Biotechnology
The need for a more sustainable society has prompted the development of bio-based processes to produce fuels, chemicals, and materials in substitution for fossil-based ones. In this context, microorganisms have been employed to convert renewable carbon sources into various products. The methylotrophic yeast Komagataella phaffii has been extensively used in the production of heterologous proteins. The obligate aerobic yeast Komagataella phaffii is a non-pathogenic certified and generally recognized as a safe (GRAS) microorganism. It is classified in the Saccharomycetales order and Saccharomycetaceae family.
587
10 Nov 2022
Topic Review
P. ginseng
in Reactive Oxygen Species-Mediated Diseases
Reactive oxygen species (ROS)-the byproduct of regular cell activity formed by various cellular components—play a significant role in pathological and physiological conditions. Alternatively, antioxidants are compounds that reduce or scavenge reactive species in cells. An asymmetry between the antioxidant defense system and ROS from intracellular and extracellular sources cause chronic diseases such as cancer, inflammation, tumorigenesis, cardiovascular and neurogenerative diseases. P. ginseng and its derivatives are some of the antioxidant-rich sources involved in the regulation of many oxidative-stress-related pathways.
585
13 Mar 2023
Topic Review
Pichia pastoris
Strains as Powerful Cell Factories
Pichia pastoris is the most widely used microorganism for the production of secreted industrial proteins and therapeutic proteins. This yeast has been repurposed as a cell factory for the production of chemicals and natural products.
338
19 Jan 2024
Topic Review
Salmonella
as a Promising Curative Tool against Cancer
Bacteria-mediated cancer therapy has become a topic of interest under the broad umbrella of oncotherapy. Among many bacterial species, Salmonella remains at the forefront due to its ability to localize and proliferate inside tumor microenvironments and often suppress tumor growth. Salmonella Typhimurium is one of the most promising mediators, with engineering plasticity and cancer specificity. It can be used to deliver toxins that induce cell death in cancer cells specifically, and also as a cancer-specific instrument for immunotherapy by delivering tumor antigens and exposing the tumor environment to the host immune system.
403
02 Nov 2022
Topic Review
Trypanosoma cruzi
Disperse Gene Protein Family (DGF-1)
Chagas disease, caused by Trypanosoma cruzi infections, is included in the group of neglected diseases, and efforts to develop new therapeutic or immunoprevention approaches have not been successful. After the publication of the T. cruzi genome, the number of molecular and biochemical studies on this parasite has increased considerably, many of which are focused on families of variant surface proteins, especially trans-sialidases, mucins, and mucin-associated proteins. The disperse gene protein 1 family (DGF-1) is one of the most abundant families in the T. cruzi genome.
348
15 Mar 2023
Topic Review
16S rRNA Sequencing vs. Metagenome Sequencing
Microbiome research has revolutionized our understanding of complex microbial communities, and two pivotal techniques at the forefront of this exploration are 16S rRNA sequencing and metagenome sequencing.
93
01 Aug 2024
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