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Topic Review
Biography
Topic Review
FDA Approved Antibody-Drug Conjugates
Antibody-drug conjugate (ADC) are now amongst the fastest growing drug classes in oncology, as they combine the best features of mAbs and small molecule drugs, creating a single moiety that is highly specific and cytotoxic.
2.2K
16 Nov 2021
Topic Review
Atomically Dispersed Catalytic Sites for Photocatalytic Water Splitting
SAPCs provide a new pathway for the construction of high performance cocatalyst/photocatalyst composites. For the past few years, the preparation method, characterization technology, theoretical modeling, and mechanism investigation of SAPCs have been developed rapidly, promoting the rational design and fabrication of more efficient SAPCs. As discussed above, benefitting from their low-coordination status, unique electric structures, and metal-support interactions, SAPCs can bring about unique advantages in comparison with the nanocluster-based, nanoparticle-based, and bulk catalysts.
615
15 Nov 2021
Topic Review
Mannich-type substitution of KYNA derivatives
Kynurenic acid (KYNA) is an endogenous neuroprotective agent of increasing importance. Several derivatives have already been synthesized, bearing an abundance of functional groups attached to the main skeleton in different positions. Several of these compounds have already been tested in biological evaluations, with several of them targeting the same receptors and biological effects as KYNA.
399
15 Nov 2021
Topic Review
Thermochromic Polymeric Films
Polymers as smart temperature sensors
771
12 Nov 2021
Topic Review
Properties of Multi-Dimensional Biological Models with Cross-Scale Features
The rise in structural performance requirements in engineering is driving the research and development of stronger, stiffer, and lighter materials. However, most traditional artificial materials are unable to meet the needs of modern industrial and technological development. In fact, multifarious creatures in nature are further ahead in their use of structural materials. There is a fairly limited selection of natural structural materials at ambient temperatures. They usually consist of hard and soft phases arranged in a complex hierarchy with characteristic dimensions ranging from nanoscale to macroscale. The resulting materials usually show a nearly perfect combination of strength and toughness integrated with lightweight characteristics. This is exactly what is required of engineering materials.
651
12 Nov 2021
Topic Review
{001} Faceted Anatase TiO2-Based Composites
For anatase TiO2, the {001} crystal facets are the most reactive because they exhibit unique surface characteristics such as visible light responsiveness, dissociative adsorption, efficient charge separation capabilities and photocatalytic selectivity. In this review, a concise survey of the literature in the field of {001} dominated anatase TiO2 crystals and their composites is presented. Even though the design and morphologically controlled synthesis of TiO2-001 is considered to be a hot spot in scientific research, it still has some drawbacks like its wide band gap and high recombination rate. These drawbacks can easily be overcome by coupling them with other materials to form TiO2-001-based composites. This review focusses on the synthesis, properties and applications of TiO2-001-based composites.
1.2K
12 Nov 2021
Topic Review
Waste Natural Polymers
Waste natural polymers have received much attention as renewable, biodegradable, non-toxic and low-cost filler in polymer composites. In order to exploit the high potential for residual natural loading in latex composites, different types of surface modification techniques have been applied. This review discusses the preparation and characterization of the modified waste natural fillers for latex-based composites. The potency of the waste natural filler for the latex-based composites was explored with a focus on the mechanical, thermal, biodegradability and filler–latex interaction.
596
12 Nov 2021
Topic Review
Copper Nanocluster and Pollutant Analysis
Copper nanoclusters (Cu NCs) with their inherent optical and chemical advantages have gained increasing attention as a kind of novel material that possesses great potential, primarily in the use of contaminants sensing and bio-imaging. With a focus on environmental safety, this article comprehensively reviews the recent advances of Cu NCs in the application of various contaminants, including pesticide residues, heavy metal ions, sulfide ions and nitroaromatics. The common preparation methods and sensing mechanisms are summarized.
573
12 Nov 2021
Topic Review
Indole Derivatives as Anti-Lung Cancer Agents
Indole scaffold is considered one of the most privileged scaffolds in heterocyclic chemistry. Indole may serve as an effective probe for the development of new drug candidates against challenging diseases, including lung cancer.
1.0K
12 Nov 2021
Topic Review
Brassica Bioactives on Human Health
Brassica vegetables and their components, the glucosinolates, have been suggested as good candidates as dietary coadjutants to improve health in non-communicable diseases (NCDs).
494
12 Nov 2021
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