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Topic Review
TRPV3 Ion Channel
Transient receptor potential vanilloid subtype 3 (TRPV3) is an ion channel with a sensory function that is most abundantly expressed in keratinocytes and peripheral neurons. TRPV3 plays a role in Ca2+ homeostasis due to non-selective ionic conductivity and participates in signaling pathways associated with itch, dermatitis, hair growth, and skin regeneration. TRPV3 is a marker of pathological dysfunctions, and its expression is increased in conditions of injury and inflammation.
  • 391
  • 24 May 2023
Topic Review
Mammalian Acute Wound Healing
The limited ability of mammals to regenerate has garnered significant attention, particularly in regard to skin wound healing (WH), which is a critical step for regeneration. In human adults, skin WH results in the formation of scars following injury or trauma, regardless of severity. This differs significantly from the scarless WH observed in the fetal skin of mammals or anamniotes. 
  • 423
  • 24 May 2023
Topic Review
Health Benefits of Curcumin
Curcumin is the principal curcuminoid found in the rhizomes of turmeric. Due to its therapeutic action against cancer, depression, diabetes, some bacteria, and oxidative stress, it has been used widely in medicine since ancient times.
  • 250
  • 24 May 2023
Topic Review
Calcium and Autophagy in Alzheimer’s Disease
Alzheimer’s disease (AD) is an age-related brain disorder that causes progressive neurodegeneration predominantly in the cortical and hippocampal brain regions. Major hallmarks of AD are the progressive impairment of memory storage and accumulation of fibrillary amyloid plaques in patient’s brains. Autophagy is a process that maintains healthy cells, organelles, proteins, and nutrient homeostasis in living organisms. Three types of autophagy are observed in mammalian cells depending on the mode of substrate delivery: macroautophagy, chaperone-mediated autophagy, and microautophagy.
  • 368
  • 24 May 2023
Topic Review
Cardiac Repair and Regeneration
After more than 20 years following the introduction of regenerative medicine to address the problem of cardiac diseases, still questions arise as to the best cell types and materials to use to obtain effective clinical translation. Now that it is definitively clear that the heart does not have a consistent reservoir of stem cells that could give rise to new myocytes, and that there are cells that could contribute, at most, with their pro-angiogenic or immunomodulatory potential, there is fierce debate on what will emerge as the winning strategy.
  • 380
  • 23 May 2023
Topic Review
Organ Abnormalities Caused by Turner Syndrome
Turner syndrome (TS), a genetic disorder due to incomplete dosage compensation of X-linked genes, affects multiple organ systems, leading to hypogonadotropic hypogonadism, short stature, cardiovascular and vascular abnormalities, liver disease, renal abnormalities, brain abnormalities, and skeletal problems. Patients with TS experience premature ovarian failure with a rapid decline in ovarian function caused by germ cell depletion, and pregnancies carry a high risk of adverse maternal and fetal outcomes. Aortic abnormalities, heart defects, obesity, hypertension, and liver abnormalities, such as steatosis, steatohepatitis, biliary involvement, liver cirrhosis, and nodular regenerative hyperplasia, are commonly observed in patients with TS.
  • 644
  • 23 May 2023
Topic Review
Key Aspects of Coronavirus Avian Infectious Bronchitis Virus
Infectious bronchitis virus (IBV) is an enveloped and positive-sense single-stranded RNA virus. IBV was the first coronavirus to be discovered and predominantly causes respiratory disease in commercial poultry worldwide.
  • 305
  • 23 May 2023
Topic Review
Insects for Sustainable Aquaculture
One of the greatest challenges to achieving a sustainable aquaculture is finding alternatives to fishmeal as a primary protein source in aquafeeds. Insects represent one of the most promising alternatives being explored and produced as replacements for this ingredient.
  • 394
  • 23 May 2023
Topic Review
Camelina sativa
Camelina sativa (L.) Crantz, also called gold-of-pleasure, false flax, or linseed dodder, is an oilseed crop belonging to the tribe Camelineae of the mustard family (Brassicaceae). Camelina is a hardy plant that adapts very well to different types of soil and grows best in cool semi-arid climates. The great potential of this crop is also being exploited to obtain a sustainable feedstock for its different applications, and to improve dryland agriculture. Camelina can be used to improve the quality of foods, such as dairy products and meat, and the consumption of its oil has potential benefits for human health.
  • 696
  • 23 May 2023
Topic Review
Effect of Cd on Gene Expression in Plants
Cadmium (Cd) is a heavy metal that can cause damage to living organisms at different levels. Even at low concentrations, Cd can be toxic to plants, causing harm at multiple levels.Previous studies have shown that Cd negatively affects the regulation of energy metabolism genetics pathways, genetics hormone pathways, enzymatic genetics pathways, and phytohormone biosynthesis. These ultimately interfere with the expression of genes in response to Cd-induced stress.
  • 260
  • 23 May 2023
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