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Topic Review
Sputtering of LiCoO2 Thin Films
Lithium cobalt oxide (LCO) cathode has been widely applied in 3C products (computer, communication, and consumer), and LCO films are the most promising cathode materials for thin-film lithium batteries (TFBs) due to their high volumetric energy density and favorable durability. Magnetron sputtering deposition technology realizes the merits of high speed, low temperature, and low toxicity. The magnetron sputtering technology perfectly fits the microelectronics, micro-memory, and other micro-devices in the field of low energy demand, and has even gradually been expanded to flexible devices and implantable medical devices. Therefore, magnetron sputtering has become the most common method for making LCO thin-film electrodes. 
  • 1.5K
  • 08 Dec 2022
Topic Review
Huntingtin and Other Neurodegeneration-Associated Proteins in Intracellular Pathologies
Neurodegenerative diseases are currently incurable. Numerous experimental data accumulated over the past fifty years have brought us closer to understanding the molecular and cell mechanisms responsible for their development. It is known that the basis of neurodegenerations are proteinopathies, disorders in the structure and function of various proteins that lead to their aggregation and toxic effects on cells. The most common neurodegenerative proteinopathies are amyloidosis (amyloid extracellular plaques in AD), tauopathy (various dementias), α-synucleopathy (Lowy bodies in PD), prionopathy, and TDP-43 proteinopathy (in amyotrophic lateral sclerosis (ALS)).
  • 1.5K
  • 26 Dec 2022
Topic Review
Synchronicity
An article about the term "synchronicity" defined as the occurrence of meaningful coincidences that seem to have no cause.
  • 1.5K
  • 14 Jan 2025
Topic Review
Crystalline Peroxosolvates
Peroxosolvates - adducts of hydrogen peroxide and molecules or salts formed by hydrogen bonding.
  • 1.5K
  • 19 Jan 2021
Topic Review
ANN in Intelligent Attendance System
Determining the rate of student attendance is an important task in determining the completion of the courses. Despite the success of the technology, it is unfortunate that in many academic institutions, the current systems used to detect student absences. Furthermore, one of the crucial problems in the attendance system does not count student background for continuing in the courses. In this paper, we propose an intelligent approach for calculating student attendance based on their Grade Point Average (GPA) and their activities, this approach uses Artificial Neural Network (ANN) for calculating the attendance rating accurately, meaning the system provide a new rating for each student based on their background. The aim of this research is developing an attendance system for motivation students taking attendance or taking high grade in the class. The result of this approach helps the instructor to allow students who have more activities with more absents to continue in the courses if not the students have low activity should taking high attendance. This system will more efficient for monitoring students for replacing absent to activity.
  • 1.5K
  • 28 Oct 2020
Topic Review
Bacterial Virulence Factors
There are several levels to influence the expression of eukaryotic genes. A first level of interference is changing of the DNA’s structure on the chromatin level. Epigenetic modulation enables remodelling of the chromatin to transfer heterochromatin into euchromatin allowing transcription or vice versa. In addition, the affinity of promotors and other regulatory DNA sequences for RNA polymerases and transcription factors (TFs) can be influenced by cytosine or adenine methylation. Only a minor portion (fewer than 2%) of genes is transcribed into mRNAs, instead the majority is transferred into so called non-coding RNAs (ncRNAs). Certain long ncRNAs (lncRNAs) are also involved in epigenetic regulations. Epigenetic mechanisms are used for manipulation of gene expression in the course of several cellular processes. Here, we give an overview on the epigenetic control of gene expression by bacterial virulence factors during host cell infection.
  • 1.5K
  • 27 Oct 2020
Topic Review
Flavonoid
A particular group of phytochemicals, called flavonoids, have shown a wide range of biological effects, including antiviral activities. The molecular mechanisms of their antiviral effects mainly consist in the inhibition of viral neuraminidase, proteases and DNA/RNA polymerases, as well as in the modification of various viral proteins. Mixtures of different flavonoids or combination of flavonoids with antiviral synthetic drugs provide an enhancement of their antiviral effects. Frequent viral infections worldwide have led to the need for new effective antiviral agents, which can be identified among the various flavonoids.
  • 1.5K
  • 27 Aug 2020
Topic Review
Non-Dairy Plant-Based Probiotic
Probiotics are live microorganisms which, when administered in adequate amounts, confer a health benefit on the host. Traditionally, dairy products are the major and most popular probiotic carriers. At present, there is a growing demand for non-dairy probiotic products. Both fermented and non-fermented non-dairy plant-based food products are becoming highly appealing to both dairy and non-dairy consumers worldwide. Non-dairy plant-based food matrices such as fruits, vegetables, plant-based milk, cereals, and legumes have been used successfully in producing probiotic products with the minimum recommended viable probiotic numbers at the time of consumption. 
  • 1.5K
  • 20 Jul 2021
Topic Review
ER-Phagy and Its Diseases Relevance
Autophagy with endoplasmic reticulum (ER) as a specific substrate is called ER-phagy or reticulophagy. It occurs both under physiological conditions at the basal level, and when cells are insulted by starvation, UPR, toxin stimulation, and many other internal or external environmental changes, to achieve cell homeostasis by removing damaged or excess ER.
  • 1.5K
  • 23 Sep 2021
Topic Review
Polymers-Based Flexible Supercapacitors for Energy
Flexible supercapacitors are highly demanding due to their wearability, washability, lightweight property and rollability. Supercapacitors are specially designed capacitors which have huge capacitance value and energy density when compared to the conventional capacitors that are with fast storage ability and high energy density than capacitors
  • 1.5K
  • 08 Apr 2022
Topic Review
Targets of Toxicity in Environmental Exposure to Cadmium
Dietary assessment reports and population surveillance programs show that chronic exposure to low levels of environmental cadmium (Cd) is inevitable for most people, and adversely impacts the health of children and adults.
  • 1.5K
  • 01 Sep 2022
Topic Review
3D Printing Technologies in Dentistry
3D-printing application in dentistry not only enables the manufacture of patient-specific devices and tissue constructs, but also allows mass customization, as well as digital workflow, with predictable lower cost and rapid turnaround times.
  • 1.5K
  • 16 Sep 2022
Topic Review
Plant Growth and Development of Broccoli
Broccoli (Brassica oleracea L. var. italica Plenck.) is nowadays one of the most important vegetable crops worldwide, with an increasing demand by the market, due to its high nutritional value. From an agronomic point of view, the growth and development of broccoli can be divided into two stages; the first one starting from the transplanting to the onset of the head’s formation, which includes the meristem differentiation from vegetative to reproductive and the second one lasts from the onset of the head’s formation to its harvest. Both stages are strongly dependent on the environmental conditions (temperature, solar radiation, relative humidity, etc.) during cultivation, but each stage responds differently to them, which in turn makes it difficult to predict the effects on crop yield and head quality. 
  • 1.5K
  • 21 Nov 2022
Topic Review
NMR-Based Metabolomics in Food Quality Assessment
The ability of nuclear magnetic resonance spectroscopy (NMR) to extract chemical information from a complex mixture is invaluable and widely described in literature. Many applications of this technique in the foodomics field have highlighted how NMR could characterize food matrices, and it can be used all along its “life chain”: from farm to fork and from fork to the digestion process. 
  • 1.5K
  • 19 Jan 2023
Topic Review
The Distinction between Constitutional SGA and FGR Infants
Data regarding the nutritional management of preterm small for gestational age (SGA) infants are scarce. In the recent report of ESPGHAN, the recommended energy for very preterm infants during hospitalization has been increased, yet this may not fit the needs of all preterm infants. It is important to distinguish fetal growth-restricted (FGR) infants from constitutional SGA infants, as well as preterm SGA from preterm AGA infants, since they may have different nutritional needs. Preterm FGR infants, and specifically infants < 29 weeks’ gestation, accumulate nutrient deficits due to intrauterine malnutrition, prematurity, morbidities, delayed initiation of feeding, and feeding intolerance. Therefore, these infants may need more aggressive nutrition for optimal catch-up growth and neurologic development. 
  • 1.5K
  • 25 Jun 2023
Topic Review
Amazon Natural Fibers
The Amazon rainforest, spanning multiple countries in South America, is the world’s largest equatorial expanse, housing a vast array of relatively unknown plant and animal species. Encompassing the planet’s greatest flora, the Amazon offers a tremendous variety of plants from which natural lignocellulosic fibers (NLFs) can be extracted. In this century, NLFs, which have long been utilized by indigenous populations of the Amazon, have garnered interest as potential reinforcements for composites, whether polymer- or cement-based, in various technical applications such as packaging, construction, automotive products, and ballistic armor. A comparison with synthetic materials like glass, carbon, and aramid fibers, as well as other established NLFs, highlights the cost and specific property advantages of Amazon natural fibers (ANFs). 
  • 1.5K
  • 25 Jan 2024
Topic Review
Sexological Testing
Sexuality can be inscribed in a multidimensional model comprising different aspects of human life: biology, reproduction, culture, entertainment, relationships and love. In the last decades, a growing interest towards sexuality and a greater quest to acknowledge a "right to sexuality" has occurred both in society and individuals. The consequence of this evolution has been a renewed and more explicit call for intervention from those who suffer, or think they suffer from alterations of their sexual and relational sphere. This has produced an increased attention of medicine and psychology towards sexual dysfunctions and the problems they cause in individuals and couples. Science has gradually adjusted already existing research tools, mostly used in other fields of clinical research, to the field of sexology, so completing and increasing the number of tools in the "toolkit" of various branches of sexological diagnosis. Psychological measurements cannot be considered as accurate as physical ones (weight, height, mass, etc.), as the former evaluate those aspects and variables pertaining to an "individual" whose individuality refers to his/her own psychological, personological and environmental constituents: emotions, expressiveness, senses, feelings and experiences which can greatly vary according to the subjects and change in the short period or depending on different settings, even in the same individual. What is expected of psychological measurements is "sufficient" accuracy and reliability, i.e. capability to express an indication or focus which clinicians can use as a "guideline" to rapidly and accurately deepen the aspects highlighted by the measurements and check them together with their patients. For this purpose, several statistical validation indexes of psychodiagnostic tests are provided: from standardization to various constructions of validity (internal, external, face, construct, convergent, content, discriminant, etc.). There are several sexual dysfunctions and each of them has a different cause. Therefore, the field of sexology provides different psychological evaluation devices in order to examine the various aspects of the discomfort, problem or dysfunction, regardless of whether they are individual or relational ones. The number of psychodiagnostic reactives is certainly wide and heterogeneous, nevertheless, the number of tests specifically meant for the field of sexology is quite limited. The following list (in alphabetical order) is not exhaustive but shows the best known and/or most used reactives in the field of sexological and relational psychodiagnosis.
  • 1.5K
  • 17 Nov 2022
Topic Review
Building Associated Fungi and How to Find Them
The number of buildings experiencing humidity problems and fungal growth appears to be increasing as energy-saving measures and changes in construction practices and climate become more common. Determining the cause of the problem and documenting the type and extent of fungal growth are complex processes involving both building physics and indoor mycology. The most reported building-associated fungi across all materials are Penicillium chrysogenum and Aspergillus versicolor. Chaetomium globosum is common on all organic materials, whereas Aspergillus niger is common on all inorganic materials.
  • 1.5K
  • 29 Feb 2024
Topic Review
Ethical Approach in Echinoderms
The majority of ethical and welfare approaches in animal research have primarily focused on vertebrates. Echinoderms are a phylum of marine invertebrates. They are often key, long-living species that shape and maintain the status of many marine ecosystems, inhabiting a wide range of ecological niches from the abyssal depths of the oceans to the intertidal zone. Progress has been made toward developing an ethical framework for invertebrates, such as crustaceans, echinoderms, and cephalopods.
  • 1.5K
  • 15 Nov 2023
Topic Review
CD73
Regulatory networks controlling cellular plasticity, important during early development, can re-emerge after tissue injury and premalignant transformation. One such regulatory molecule is the cell surface ectoenzyme ecto-5′-nucleotidase that hydrolyzes the conversion of extracellular adenosine monophosphate to adenosine (eADO). Ecto-5′-nucleotidase (NT5E) or cluster of differentiation 73 (CD73), is an enzyme that is encoded by NT5E in humans. In normal tissue, CD73-mediated generation of eADO has important pleiotropic functions ranging from the promotion of cell growth and survival, to potent immunosuppression mediated through purinergic G protein-coupled adenosine receptors. Importantly, tumors also utilize several mechanisms mediated by CD73 to resist therapeutics and in particular, evade the host immune system, leading to undesired resistance to targeted therapy and immunotherapy. Tumor cell CD73 upregulation is associated with worse clinical outcomes in a variety of cancers. Emerging evidence indicates a link between tumor cell stemness with a limited host anti-tumor immune response.
  • 1.5K
  • 21 Jan 2021
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