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Topic Review
Blending Pulse and Wheat Flours on Baked Goods
Bread is one of the most widely consumed foods in all regions of the world. Wheat flour being its principal ingredient is a cereal crop low in protein. The protein content of a whole grain of wheat is about 12–15% and is deficit in some essential amino acids, for example, lysine. Conversely, the protein and fibre contents of legume crops are between 20 and 35% and 15 and 35%, respectively, depending on the type and cultivar of the legume. The importance of protein-rich diets for the growth and development of body organs and tissues as well as the overall functionality of the body is significant. The addition of plant-based protein flours has been shown to produce an improved quality characteristic, especially the nutritional quality aspect of bread.
  • 1.6K
  • 07 Nov 2022
Topic Review
Natural Esters Additives to Improve the Properties
Regardless of their environmental and technical merits, natural esters have some limitations that are slowing down their total acceptance by transformer owners and utilities. Critical limitations and concerns include esters’ pour point, viscosity, oxidative stability, and ionization resistance.
  • 1.6K
  • 04 Jan 2023
Topic Review
Public–Private Partnerships Model Applied to Hospitals
When the public–private partnership (PPP) model is applied to healthcare (hospitals), it is possible to discover the path to success by developing a critical assessment and deriving a clear model. Most PPP model implementations in hospitals around the world have produced favorable outcomes, both in terms of the performance of healthcare units and in terms of cost-effectiveness. 
  • 1.6K
  • 25 Jun 2023
Topic Review
Coenzyme Q10 in Cardiovascular Diseases
Coenzyme Q10 (CoQ10) is a ubiquitous factor present in cell membranes and mitochondria, both in its reduced (ubiquinol) and oxidized (ubiquinone) forms. Its levels are high in organs with high metabolism such as the heart, kidneys, and liver because it acts as an energy transfer molecule but could be reduced by aging, genetic factors, drugs (e.g., statins), cardiovascular (CV) diseases, degenerative muscle disorders, and neurodegenerative diseases. As CoQ10 is endowed with significant antioxidant and anti-inflammatory features, useful to prevent free radical-induced damage and inflammatory signaling pathway activation, its depletion results in exacerbation of inflammatory processes. Therefore, exogenous CoQ10 supplementation might be useful as an adjuvant in the treatment of cardiovascular diseases such as heart failure, atrial fibrillation, and myocardial infarction and in associated risk factors such as hypertension, insulin resistance, dyslipidemias, and obesity.
  • 1.6K
  • 09 Jun 2021
Topic Review
Bio-inspired surface texture modification
The imitation of natural systems to produce effective antifouling materials is often referred to as “biomimetics”.  Looking to the marine environment for bioinspired surfaces offers researchers a wealth of topographies to explore. Attention is given to the evaluation of textures based on marine organisms tested in either the laboratory or the field. The findings of the review relate to the numbers of studies on textured surfaces demonstrating antifouling potential which are significant. Many textures are only tested in the laboratory, where it is acknowledged a very different response to fouling is observed when tested in the field.  
  • 1.6K
  • 22 Jan 2021
Topic Review
Targeting Gut Microbial Biofilms
Colorectal cancer (CRC) is a global public health issue which poses a substantial humanistic and economic burden on patients, healthcare systems and society. In recent years, intestinal dysbiosis has been suggested to be involved in the pathogenesis of CRC, with specific pathogens exhibiting oncogenic potentials such as Fusobacterium nucleatum, Escherichia coli and enterotoxigenic Bacteroides fragilis having been found to contribute to CRC development. More recently, it has been shown that initiation of CRC development by these microorganisms requires the formation of biofilms. Gut microbial biofilm forms in the inner colonic mucus layer and is composed of polymicrobial communities. Biofilm results in the redistribution of colonic epithelial cell E-cadherin, increases permeability of the gut and causes a loss of function of the intestinal barrier, all of which enhance intestinal dysbiosis. This literature review aims to compile the various strategies that target these pathogenic biofilms and could potentially play a role in the prevention of CRC. We explore the potential use of natural products, silver nanoparticles, upconverting nanoparticles, thiosalicylate complexes, anti-rheumatic agent (Auranofin), probiotics and quorum-sensing inhibitors as strategies to hinder colon carcinogenesis via targeting colon-associated biofilms.
  • 1.6K
  • 22 Oct 2020
Topic Review
CRISPR, Livestock, Sustainable Food Production
The growing demand for animal source foods to feed people has been pushing the livestock industry to increase productivity, a tendency that will continue throughout this century. The challenge for the coming years is to increase the food supply to ensure equity in access to high quality food, while maintaining global sustainability including combating climate change, avoiding deforestation, and conserving biodiversity, as well as ensuring animal health and welfare. The question is, how do we produce more with less? Classical methods to enhance livestock productivity based on the improvement of animal health, nutrition, genetics, reproductive technologies and management have made important contributions; however, this is not going to be enough and thus disruptive approaches are required. Genome editing with CRISPR may be a powerful contributor to global livestock transformation. 
  • 1.6K
  • 28 Jun 2021
Topic Review
Cardiac Neural Crest Cells
Cardiac neural crest cells (NCCs), a specified subpopulation of the neural crest (NC), are vital for normal cardiovascular development, as they significantly contribute to the pharyngeal arch arteries, the developing cardiac outflow tract (OFT), cardiac valves, and interventricular septum. Various signaling pathways and factors are shown to orchestrate the proper migration, compaction, and differentiation of cardiac NCCs during cardiovascular development. Any loss or dysregulation of various signaling components in cardiac NCCs can lead to abnormal cardiovascular development during embryogenesis, resulting in abnormalities categorized as congenital heart defects (CHDs).
  • 1.6K
  • 10 Aug 2021
Topic Review
Interaction of Milk Protein Concentrates with Plant-Based Polyphenolics
Functional properties and biological activities of plant-derived polyphenolic compounds have gained great interest due to their epidemiologically proven health benefits and diverse industrial applications in the food and pharmaceutical industry. Moreover, the food processing conditions and certain chemical reactions such as pigmentation, acylation, hydroxylation, and glycosylation can also cause alteration in the stability, antioxidant activity, and structural characteristics of the polyphenolic compounds. Since the (poly)phenols are highly reactive, to overcome these problems, the formulation of a complex of polyphenolic compounds with natural biopolymers is an effective approach. Besides, to increase the bioavailability and bioaccessibility of polyphenolic compounds, milk proteins such as whey protein concentrate, sodium caseinate, and milk protein concentrate act as natural vehicles, due to their specific structural and functional properties with high nutritional value. Therefore, milk proteins are suitable for the delivery of polyphenols to parts of the gastrointestinal tract.
  • 1.6K
  • 21 Dec 2021
Topic Review
Sport in the School Environment
With regard to school-related physical activities, extended educational sports activities become more important in all-day schools. These activities include supervised sports classes after lessons, unsupervised opportunities during lunchtime, and free physical activities during recess, as well as before and after lessons. 
  • 1.6K
  • 25 Mar 2022
Topic Review
Rainfall Prediction System
Rainfall prediction is one of the challenging tasks in weather forecasting process. Accurate rainfall prediction is now more difficult than before due to the extreme climate variations.
  • 1.6K
  • 18 May 2022
Topic Review
Nanozyme Platforms for Antibacterial Applications
Some key enzymes or classes of enzymes, such as superoxide dismutase (SOD), catalase (CAT), oxidase (OXD), peroxidase (POD), deoxyribonuclease (DNase), etc., have been implicated in antibacterial therapy.
  • 1.6K
  • 21 Jun 2022
Topic Review
Java Card Open Platform
Java Card OpenPlatform (JCOP) is a smart card operating system for the Java Card platform developed by IBM Zürich Research Laboratory. On 31 January 2006 the development and support responsibilities transferred to the IBM Smart Card Technology team in Böblingen, Germany . Since July 2007 support and development activities for the JCOP operating system on NXP / Philips silicon are serviced by NXP Semiconductors. The title originates from the standards it complies with: A Java Card JCOP has a Java Card Virtual Machine (JCVM) which allows it to run applications written in Java programming language.
  • 1.6K
  • 22 Nov 2022
Topic Review
Development of Robotic Arm Harvesters
Promotion of research and development in advanced technology must be implemented in agriculture to increase production in the current challenging environment where the demand for manual farming is decreasing due to the unavailability of skilled labor, high cost, and shortage of labor. The demand for fruit harvester technologies, i.e., mechanized harvesting, manned and unmanned aerial systems, and robotics, has increased. However, several industries are working on the development of industrial-scale production of advanced harvesting technologies at low cost, no commercial robotic arm has been developed for selective harvesting of valuable fruits and vegetables, especially within controlled strictures, i.e., greenhouse and hydroponic contexts. 
  • 1.6K
  • 28 Nov 2023
Topic Review
CAPM and Fama and French Three-Five Factor Models
Entitled the Fama and French three-factor (hereafter, FF3F) model (1993), it embraces others risk factors in addition to the CAPM beta, such as the mimicking returns for the size factor and the mimicking returns for the book-to-market factor.
  • 1.6K
  • 02 Jan 2024
Topic Review
γ-Glutamyltransferase in Urologic Neoplasms
γ-Glutamyltransferase (GGT), a membrane-bound enzyme, contributes to the metabolism of glutathione (GSH), which plays a critical physiological role in protecting cells against oxidative stress. GGT has been proposed as a biomarker of carcinogenesis and tumor progression given that GGT activity is important during both the promotion and invasion phases in cancer cells.
  • 1.6K
  • 14 Apr 2021
Topic Review
Micro-Irrigation Technologies in India and Africa
Water is an essential resource for the realization of the United Nations’ 2030 Sustainable Development Goals. The increasing global food insecurity, hunger, human population, and uneconomical extraction and use of non-renewable resources require, among other things, a substantial intensification of agricultural production. In this context, there has been a need to adopt irrigation technologies, especially in developing countries where agriculture and its allied sectors employ more than 50% of the total population but account for up to 90% of the total freshwater consumptive use. India and Africa are at the crux of this conundrum, where there is an urgent need to build resilience with the already excessively allotted water resources. Innovative and water-efficient irrigation technologies could be one of the windows of opportunity to overcome water scarcity and enhance food security in these regions. 
  • 1.6K
  • 08 Dec 2023
Topic Review
Concepts in the Two-Process Model of Sleep Regulation
The two-process model of sleep regulation has served as a conceptual framework in the last four decades for understanding sleep physiology. In the 1970s, long-term recordings of sleep in rats were obtained thanks to EEG telemetry. NonREM sleep and REM sleep were found to differ in their time course and response to light-dark protocols. There were indications for their coupling to the circadian system, in particular the light-dark and the dark-light transitions. With the advent of quantitative EEG analysis, slow-wave activity in nonREM sleep was recognized as a sleep-wake-dependent variable. The term “sleep homeostasis” was coined to specify the regulated balance between sleep and waking. The regulatory homeostatic process was designated as “Process S”. In the two-process model, its interaction with the circadian pacemaker “Process C” can account for sleep duration under various experimental protocols. Local, use-dependent slow-wave activity changes were demonstrated in both humans and rats by the selective, unilateral activation of a cortical region prior to sleep. Finding that rest in invertebrates has sleep-like regulatory properties opened a new realm of animal studies. Comparative sleep studies in a broad variety of animal species confirmed the validity of the basic concepts of the two-process model.
  • 1.6K
  • 17 Jan 2024
Topic Review
Wind Turbine
Wind Turbine Power Curve models establish a simplified way to apply the relationship between the wind speed at hub height and the output power of the wind turbine. When dealing with deterministic models, two main types appear: polynomial and sigmoid. 
  • 1.6K
  • 27 Oct 2020
Topic Review
PRISMA Statement
The bioethanol sector is an extremely complex set of actors, technologies and market structures, influenced simultaneously by di erent natural, economic, social and political processes. That is why it lends itself to the application of system dynamics modelling. In last five years a relatively high level of experience and knowledge has accumulated related to the application of computer-aided system modelling for the analysis and forecasting of the bioethanol sector. The goal of the current paper is to o er a systematic review of the application of system dynamics models in order to better understand the structure, conduct and performance of the bioethanol sector. Our method has been the preferred reporting items for systematic reviews and meta-analyses (PRISMA), based on English-language materials published between 2015 and 2020. The results highlight that system dynamic models have become more and more complex, but as a consequence of the improvement in information technology and statistical systems, as well as the increasing experience gained they o er an ecient tool for decision makers in the business and political spheres. In the future, the combination of traditional system dynamics modelling and agent-based models will o er new perspectives for the preparation of more sophisticated description and forecasting.
  • 1.6K
  • 28 Oct 2020
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