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Topic Review
Transgender Hormone Therapy (Male-to-female)
Transgender hormone therapy of the male-to-female (MTF) type, also known as transfeminine hormone therapy, is hormone therapy and sex reassignment therapy to change the secondary sexual characteristics of transgender people from masculine or androgynous to feminine. It is one of two types of transgender hormone therapy (the other being female-to-male) and is predominantly used to treat transgender women and other transfeminine individuals. Some intersex people also take this form of therapy, according to their personal needs and preferences. The purpose of the therapy is to cause the development of the secondary sex characteristics of the desired sex, such as breasts and a feminine pattern of hair, fat, and muscle distribution. It cannot undo many of the changes produced by naturally occurring puberty, which may necessitate surgery and other treatments to reverse (see below). The medications used for the MTF therapy include estrogens, antiandrogens, progestogens, and gonadotropin-releasing hormone modulators (GnRH modulators). While the therapy cannot undo the effects of a person's first puberty, developing secondary sex characteristics associated with a different gender has been shown to relieve some or all of the distress and discomfort associated with gender dysphoria, and can help the person to "pass" or be seen as the gender they identify with. Introducing exogenous hormones into the body impacts it at every level and many patients report changes in energy levels, mood, appetite, etc. The goal of the therapy is to provide patients with a more satisfying body that is more congruent with their gender identity.
  • 7.3K
  • 06 Oct 2022
Topic Review
Salt-Tolerant Rice
Soil salinization and a degraded ecological environment are challenging agricultural productivity and food security.  Salt stress-inhibited growth and development of plants is the key limiting factor resulting in the reduction of rice yield, the contradiction of yield promotion and salt tolerance greatly affects salt-tolerant rice breeding.  Here, we  highlight current advances and challenges to breeding salt-tolerant rice, providing a basis for further studies and efforts aimed at breeding salt-tolerant rice varieties.
  • 7.3K
  • 17 Jan 2022
Topic Review
Indian Remote Sensing Programme
India's remote sensing program was developed with the idea of applying space technologies for the benefit of human kind and the development of the country. The program involved the development of three principal capabilities. The first was to design, build and launch satellites to a sun synchronous orbit. The second was to establish and operate ground stations for spacecraft control, data transfer along with data processing and archival. The third was to use the data obtained for various applications on the ground.
  • 7.3K
  • 17 Nov 2022
Topic Review
Livelihood Vulnerability
Livelihood vulnerability can be a function of both physiological and social factors [9]. Physiological vulnerability is the extent to which communities are exposed to physical effects such as sea-level rise and an increase in sea temperature, and/or atmospheric temperature. Such exposure to climate change increases rural livelihood vulnerability and reduces households’ ability to cope with climate risks, shocks, and stress. Rural households often have limited assets and thus adaptive capacity. The social vulnerability can include factors such as relative inequality, culture, the degree of urbanisation, and the rate of economic growth.
  • 7.3K
  • 15 Jul 2021
Topic Review
The Braking Torque
A disc brake is a braking system in which a disc that rotates in solidarity with the vehicle wheel is subjected to friction by brake pads with a high coefficient of friction. The brake pads are arranged in a part called the caliper, which is in turn fixed solidly to the structure of the car. A hydraulic circuit pushes the brake pads against the disc with sufficient force to transform all or part of the kinetic energy of the vehicle in movement, into heat, until it is stopped or its speed is reduced, as the case may be.
  • 7.3K
  • 27 Oct 2020
Topic Review
Mercedes-Benz W114
The Mercedes-Benz W114 and W115 models are a series of executive sedans and coupés introduced in 1968 by Mercedes-Benz, manufactured through model year 1976, and distinguished in the marketplace by names relating to their engine size. W114 models featured six-cylinder engines and were marketed as the 230, 250, and 280, while W115 models featured four-cylinder engines and were marketed as the 200, 220, 230, and 240. All were styled by Paul Bracq, featuring a three-box design. At the time Mercedes marketed sedans in two size classes, with the W114/W115 positioned below the Mercedes-Benz S-Class. Beginning in 1968, Mercedes marketed their model range as New Generation Models, giving their ID plates the designation '/8' (due to their 1968 Launch year). Because they were the only truly new cars of the so-called 'New Generation' and because of the '/8' or 'slash eight' designation, W114 and W115 models ultimately received the German nickname Strich Acht, loosely translated into the English stroke eight.
  • 7.3K
  • 04 Nov 2022
Topic Review
List of Peaks by Prominence
This is a list of mountain peaks ordered by their topographic prominence.
  • 7.3K
  • 18 Oct 2022
Topic Review Peer Reviewed
Metaverse
The Metaverse is the post-reality universe, a perpetual and persistent multiuser environment merging physical reality with digital virtuality. It is based on the convergence of technologies that enable multisensory interactions with virtual environments, digital objects and people such as virtual reality (VR) and augmented reality (AR). Hence, the Metaverse is an interconnected web of social, networked immersive environments in persistent multiuser platforms. It enables seamless embodied user communication in real-time and dynamic interactions with digital artifacts. Its first iteration was a web of virtual worlds where avatars were able to teleport among them. The contemporary iteration of the Metaverse features social, immersive VR platforms compatible with massive multiplayer online video games, open game worlds and AR collaborative spaces.
  • 7.2K
  • 13 Apr 2022
Topic Review
NASDAQ-100
The NASDAQ-100 (^NDX) is a stock market index made up of 103 equity securities issued by 100 of the largest non-financial companies listed on the Nasdaq stock market. It is a modified capitalization-weighted index. The stocks' weights in the index are based on their market capitalizations, with certain rules capping the influence of the largest components. It is based on exchange, and it does not have any financial companies. The financial companies were put in a separate index, the NASDAQ Financial-100.
  • 7.2K
  • 19 Oct 2022
Topic Review
Bitching Betty
Bitching Betty is a slang term used by some pilots and aircrew (mainly North American), when referring to the voices used by some aircraft warning systems. The enunciating voice, in at least some aircraft systems, may be either male or female and in some cases this may be selected according to pilot preference. If the voice is female, it may be referred to as Bitching Betty; if the voice is male, it may be referred to as Barking Bob. A female voice is heard on military aircraft such as the F-16 Fighting Falcon, the Eurofighter Typhoon and the Mikoyan MiG-29. A male voice is heard on Boeing commercial airliners and is also used in the BAE Hawk. In the United Kingdom the term Nagging Nora is sometimes used, and in New Zealand the term used for Boeing aircraft is Hank the Yank. The voice warning system used on London Underground trains, which also uses a female voice, is known to some staff as Sonya, as it "gets on ya nerves".
  • 7.2K
  • 11 Oct 2022
Topic Review
Wooden Boats of World War 2
Splinter fleet or Splinter navy was a nickname given to the wooden boats used in World War II. The boats served in many different roles during the war. These boats were built in small boatyards on the West coast and East coast, Great Lakes and the Gulf of Mexico. They could be built quickly, in just 60 to 120 days. Most of the boats were built by boatyards that already had the tools and knowledge from building yachts, sailboats and motor boats. Many were built by craftsmen in family-owned small businesses. Under the Emergency Shipbuilding Program and War Shipping Administration contracts went out to over fifty boatyards across the country. The boats were built for the US Navy, the, United States Army Air Forces , United States Coast Guard, and US Army. Some of the wooden boats went to Allied nations on the Lend-Lease program. In addition to new boat construction, some wooden boats built between 1910 and 1941 were acquired for the war effort, some used as-is and others converted for war use. Wooden boats have lighter weight and are easier to repair than steel hull boats. These wooden boats ranged from 19 to 200 feet in length. Some worked near shore and others working in the open ocean, called the Blue-water navy. The Splinter fleet is in contrast to the more common steel hull war ships and Merchant Marine ships. After the war, many of these boats were deemed not needed. Many were abandoned or destroyed, a few served in the Korean war and a few in the Vietnam War, some sold to private and some donated. During World War I there was a debate as to if wooden boats and ships should be used in war time. William Denman, President of the Emergency Fleet Corporation supported the building of wooden ships for the war and General Goethals disapproved. In the end, both men turned in their resignation over the heated debate. During World War II the situation was different. There was a shortage of steel and steel shipyards, so there was no debate about the need for a vast wooden fleet of boats and ships.
  • 7.2K
  • 14 Oct 2022
Topic Review
Hypertensive Nephropathy
Hypertension is one of the most common risk factors for developing chronic cardiovascular diseases, including hypertensive nephropathy. Within the glomerulus, hypertension causes damage and activation of mesangial cells (MCs), eliciting the production of large amounts of vasoactive and proinflammatory agents. Accordingly, the activation of AT1 receptors by the vasoactive molecule angiotensin II (AngII) contributes to the pathogenesis of renal damage, which is mediated mostly by the dysfunction of intracellular Ca2+ ([Ca2+]i) signaling. Similarly, inflammation entails complex processes, where [Ca2+]i also play crucial roles. Deregulation of this second messenger increases cell damage and promotes fibrosis, reduces renal blood flow, and impairs the glomerular filtration barrier. In vertebrates, [Ca2+]i signaling depends, in part, on the activity of two families of large-pore channels: hemichannels and pannexons. Interestingly, the opening of these channels depends on [Ca2+]i signaling. 
  • 7.2K
  • 23 Dec 2022
Topic Review
Glossary of Bird Terms
The following is a glossary of common English language terms used in the description of birds—warm-blooded vertebrates of the class Aves and the only living dinosaurs, characterized by feathers, the ability to fly in all but the approximately 60 extant species of flightless birds, toothless, beaked jaws, the laying of hard-shelled eggs, a high metabolic rate, a four-chambered heart and a strong yet lightweight skeleton. Among other details such as size, proportions and shape, terms defining bird features developed and are used to describe features unique to the class—especially evolutionary adaptations that developed to aid flight. There are, for example, numerous terms describing the complex structural makeup of feathers (e.g., barbules, rachides and vanes); types of feathers (e.g., filoplume, pennaceous and plumulaceous feathers); and their growth and loss (e.g., colour morph, nuptial plumage and pterylosis). There are thousands of terms that are unique to the study of birds. This glossary makes no attempt to cover them all, concentrating on terms that might be found across descriptions of multiple bird species by bird enthusiasts and ornithologists. Though words that are not unique to birds are also covered, such as "back" or "belly", they are defined in relation to other unique features of external bird anatomy, sometimes called "topography". As a rule, this glossary does not contain individual entries on any of the approximately 9,700 recognized living individual bird species of the world.
  • 7.2K
  • 09 Nov 2022
Topic Review
Softmod
A softmod is a method of using software to modify the intended behavior of hardware, such as video cards, sound cards, or game consoles in a way that can overcome restrictions of the firmware, or install custom firmware.
  • 7.2K
  • 23 Nov 2022
Topic Review
Sweatshop
A sweatshop or sweat factory is a crowded workplace with very poor, socially unacceptable or illegal working conditions. The work may be difficult, dangerous, climatically challenging or underpaid. Workers in sweatshops may work long hours with low pay, regardless of laws mandating overtime pay or a minimum wage; child labor laws may also be violated. The Fair Labor Association's "2006 Annual Public Report" inspected factories for FLA compliance in 18 countries including Bangladesh, El Salvador, Colombia, Guatemala, Malaysia, Thailand, Tunisia, Turkey, China, India, Vietnam, Honduras, Indonesia, Brazil, Mexico, and the US. The U.S. Department of Labor's "2015 Findings on the Worst Forms of Child Labor" found that "18 countries did not meet the International Labour Organization's recommendation for an adequate number of inspectors."
  • 7.2K
  • 31 Oct 2022
Topic Review
Alaria alata
Alaria alata flukes are cosmopolitan parasites. In Europe, the definitive hosts are red foxes (Vulpes vulpes), wolves (Canis lupus), and raccoon dogs (Nyctereutes procyonoides), as well as animals that belong to the Felidae family. Intermediate hosts, such as snails and frogs, are the sources of infection for definitive hosts. The developmental stages of A. alata mesocercariae may occur in paratenic hosts, including many species of mammals, birds, and reptiles, as well as in wild boars (Sus scrofa), which are important from the zoonotic point of view. Alaria alata is a widespread trematode that is considered a potential cause of a human disease called alariosis, which is associated with the consumption of raw or undercooked meat of intermediate or paratenic hosts of this parasite.
  • 7.2K
  • 11 Aug 2021
Topic Review
West African Lion
The West African lion is a Panthera leo leo population in West Africa. It is listed as Critically Endangered on the IUCN Red List. This population is isolated and probably comprises fewer than 250 mature individuals. Already in 2004, the lion population in West and Central Africa was fragmented and estimated as comprising at most 1,800 individuals. The West African lion was formerly considered a distinct lion subspecies with the scientific name P. l. senegalensis. Results of phylogenetic research indicate that the West African lion population forms a distinct clade and is closely related to Central African, North African and Asian lion populations. The lion populations in North, West and Central Africa and Asia were therefore subsumed to P. l. leo in 2017.
  • 7.2K
  • 17 Oct 2022
Biography
Mohamed Al-Fayed
Mohamed Al-Fayed (/ælfaɪˈɛd/; Egyptian Arabic: محمد أنور شاكر عبد السيد الفايد‎ [mahamad el fajed]; born 27 January 1929) is an Egyptian business magnate. Fayed's business interests include ownership of Hôtel Ritz Paris and formerly Harrods Department Store, Knightsbridge. Al-Fayed sold his ownership of Fulham F.C. to Shahid Khan in 2013.[1] In his personal life
  • 7.2K
  • 05 Dec 2022
Topic Review
Can CFD Analysis Help PEM Fuel Cell Design and Operation?
Polymer electrolyte membrane (PEM) fuel cell system is an advanced power system for the future that is sustainable, clean and environmental friendly. PEM fuel cells are growing in importance as sources of sustainable energy and will doubtless form part of the changing program of energy resources in the future. PEM fuel cells are still undergoing intense development, and the combination of new and optimized materials, improved product development, novel architectures, more efficient transport processes, and design optimization and integration are expected to lead to major gains in performance, efficiency, reliability, manufacturability and cost-effectiveness. The difficult experimental environment of PEM fuel cell systems has stimulated efforts to develop models that could simulate and predict multi-dimensional coupled transport of reactants, heat and charged species using computational fluid dynamic (CFD) technology. The strength of the CFD numerical approach is in providing detailed insight into the various transport mechanisms and their interaction, and in the possibility of performing parameters sensitivity analyses. The results of CFD analyses are relevant in: conceptual studies of new designs, detailed product development, troubleshooting, and redesign. CFD analysis complements testing and experimentation, by reduces the total effort required in the experiment design and data acquisition. Relevant case studies and recent progress in CFD techniques used in PEM fuel cell development have been presented and analyzed. The CFD models are shown to be able to provide a computer-aided tool for design and optimize future PEM fuel cell with much higher power density, long cell life, and lower cost.
  • 7.2K
  • 26 Apr 2020
Topic Review
Human Body Segments
The knowledge of human body proportions and segmental properties of limbs, head and trunk is of fundamental importance in biomechanical research. Given that many methods are employed, it is important to know which ones are currently available, which data on human body masses, lengths, center of mass (COM) location, weights and moment of inertia (MOI) are available and which methods are most suitable for specific research purposes. Graphical, optical, x-ray and derived techniques, MRI, laser, thermography, has been employed for in-vivo measurement, while direct measurements involve cadaveric studies with dissection and various methods of acquiring shape and size of body segments.
  • 7.2K
  • 20 Nov 2020
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