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Topic Review
Secretory IgA
Secretory IgA (SIgA) is the dominant antibody class in mucosal secretions, it is also present in saliva and breast milk. The majority of plasma cells producing SIgA are located within mucosal membranes lining the intestines, airway and reproductive tracts, as well as mammary gland. SIgA protects against the adhesion of pathogens and their penetration into the mucosal barriers. Moreover, SIgA regulates microbiota composition at mucosa sites and provides local homeostasis.
  • 7.2K
  • 17 Jan 2021
Topic Review
May 22: 1960 Great Chilean Earthquake
Great Chilean Earthquake (1960) is the most powerful earthquake ever recorded, occurring on May 22, 1960, with a magnitude of 9.5–9.6. Originating off the coast of southern Chile, it caused widespread destruction, significant loss of life, and a massive tsunami that affected countries across the Pacific Ocean. The event led to advancements in seismology, tsunami warning systems, and disaster preparedness.
  • 7.2K
  • 21 May 2025
Topic Review
Full-Color Realization of Micro-LED Displays
Emerging technologies, such as smart wearable devices, augmented reality (AR)/virtual reality (VR) displays, and naked-eye 3D projection, have gradually entered our lives, accompanied by an urgent market demand for high-end display technologies. Ultra-high-resolution displays, flexible displays, and transparent displays are all important types of future display technology, and traditional display technology cannot meet the relevant requirements. Micro-light-emitting diodes (micro-LEDs), which have the advantages of a high contrast, a short response time, a wide color gamut, low power consumption, and a long life, are expected to replace traditional liquid-crystal displays (LCD) and organic light-emitting diodes (OLED) screens and become the leaders in the next generation of display technology. However, there are two major obstacles to moving micro-LEDs from the laboratory to the commercial market. One is improving the yield rate and reducing the cost of the mass transfer of micro-LEDs, and the other is realizing a full-color display using micro-LED chips. This study will outline the three main methods for applying current micro-LED full-color displays, red, green, and blue (RGB) three-color micro-LED transfer technology, color conversion technology, and single-chip multi-color growth technology, to summarize present-day micro-LED full-color display technologies and help guide the follow-up research.
  • 7.2K
  • 22 Dec 2020
Topic Review
Relative Humidity
Relative humidity (RH) is the ratio of the partial pressure of water vapor to the equilibrium vapor pressure of water at a given temperature. Relative humidity depends on temperature and the pressure of the system of interest. The same amount of water vapor results in higher relative humidity in cool air than warm air. A related parameter is the dew point.
  • 7.2K
  • 29 Sep 2022
Topic Review
History of the Euro
The euro came into existence on 1 January 1999, although it had been a goal of the European Union (EU) and its predecessors since the 1960s. After tough negotiations, particularly due to opposition from the United Kingdom, the Maastricht Treaty entered into force in 1993 with the goal of creating an economic and monetary union by 1999 for all EU states except the UK and Denmark (even though Denmark has a fixed exchange rate policy with the euro). In 1999 the currency was born virtually and in 2002 notes and coins began to circulate. It rapidly took over from the former national currencies and slowly expanded behind the rest of the EU. In 2009 the Lisbon Treaty finalised its political authority, the Eurogroup, alongside the European Central Bank.
  • 7.2K
  • 29 Nov 2022
Topic Review
Networked Control System
An NCS consists of control loops joined through communication networks in which both the control signal and the feedback signal are exchanged between the system and the controller.
  • 7.2K
  • 01 Apr 2021
Topic Review
Sanism
Mentalism or sanism describes discrimination and oppression against a mental trait or condition a person has, or is judged to have. This discrimination may or may not be characterized in terms of mental disorder or cognitive impairment. The discrimination is based on numerous factors such as stereotypes about neurodivergence, for example autism, learning disorders, ADHD, bipolar, schizophrenia, and personality disorders, specific behavioral phenomena such as stuttering and tics, or intellectual disability. Like other forms of discrimination such as sexism and racism, mentalism involves multiple intersecting forms of oppression, complex social inequalities and imbalances of power. It can result in covert discrimination by multiple, small insults and indignities. It is characterized by judgments of another person's perceived mental health status. These judgments are followed by actions such as blatant, overt discrimination which may include refusal of service, or the denial of human rights. Mentalism impacts how individuals are treated by the general public, by mental health professionals, and by institutions, including the legal system. The negative attitudes involved may also be internalized. The terms mentalism, from "mental", and sanism, from "sane", have become established in some contexts, though concepts such as social stigma, and in some cases ableism, may be used in similar but not identical ways. While mentalism and sanism are used interchangeably, sanism is becoming predominant in certain circles, such as academics, those who identify as mad and mad advocates and in a socio-political context where sanism is gaining ground as a movement. The movement of sanism is an act of resistance among those who identify as mad, consumer survivors, and mental health advocates. In academia evidence of this movement can be found in the number of recent publications about sanism and social work practice. Mentalism tends to be referred as mental disability, distinguishing itself from ableism, which refers to physical disability.
  • 7.2K
  • 02 Nov 2022
Topic Review
Additive Manufacturing of Turbine Blades
Additive manufacturing is a technology of transforming a 3D prototype to a physical one directly by successive addition of the required material in a layer-by-layer manner. This technique helps to manufacture the turbine blade which is the revolution of green technology for high temperature engine parts.
  • 7.2K
  • 11 Oct 2022
Topic Review
Community Counseling
Guidance and counseling is a process of helping an individual become fully aware of his/ herself and the ways in which he is responding to the influence of his/her environment. Counseling is a generic term for any of professional counseling that treats dysfunction occurring within a group of related people. This term describes a preventive system of counseling that works to combat psychological impairment through the improvement and development of community support. A community is defined as a group of interacting individuals who share a commonality. This commonality can be anything from location of residence to career interest, but a community counselor will use this common characteristic to council groups of people.
  • 7.2K
  • 17 Oct 2022
Topic Review
Deep Reinforcement Learning Applications
Deep Reinforcement Learning (DRL) combines Reinforcement Learning and Deep Learning. It is more capable of learning from raw sensors or images as input, enabling end-to-end learning, which opens up more applications in robotics, video games, NLP, computer vision, healthcare, and more. A milestone in value-based DRL is employing Deep Q-Networks (DQN) to play Atari games by Google DeepMindin 2013.
  • 7.2K
  • 02 Aug 2021
Topic Review
Liquid Hydrogen
Decarbonization plays an important role in future energy systems for reducing greenhouse gas emissions and establishing a zero-carbon society. Hydrogen is believed to be a promising secondary energy source (energy carrier) that can be converted, stored, and utilized efficiently, leading to a broad range of possibilities for future applications. 
  • 7.2K
  • 27 Sep 2021
Topic Review
Nutritional Value of Wheat
Wheat is one of the most important cereal crops in the world as it is used in the production of a diverse range of traditional and modern processed foods. The ancient varieties einkorn, emmer and spelt not only played an important role as a source of food but became the ancestors of the modern varieties currently grown worldwide. Hexaploid wheat (Triticum aestivum L.) and tetraploid wheat (Triticum durum Desf.) now account for around 95% and 5% of the world production, respectively. The success of this cereal is inextricably associated with the capacity of its grain proteins, the gluten, to form a viscoelastic dough that allows the transformation of wheat flour into a wide variety of staple forms of food in the human diet. This review aims to give a holistic view of the temporal and proteogenomic evolution of wheat from its domestication to the massively produced, high yield crop of our day.
  • 7.2K
  • 05 Nov 2021
Topic Review
Deep Cryogenic Treatment
Deep cryogenic treatment (DCT) is a type of cryogenic treatment, where a metallic material is subjected to temperatures below -150°C, normally to temperatures of liquid nitrogen (-196 °C). When a material is exposed to DCT as a part of heat treatment, changes in microstructure are induced due to new grain formation, changes in grain size, change in the solubility of atoms, movement of dislocations, alteration of crystal structure, and finally new phase formation. The metallic material's performance and later performance of manufactured components and tools from this specific material are dependent on the selection of proper design, proper material, accuracy with which the tool is made and application of proper heat treatment, including any eventual DCT. Metallic materials are ferrous and non-ferrous metals. In the last years ferrous metals (different grades of steel) and non-ferrous alloys (aluminum, magnesium, titanium, nickel etc.) have been increasingly treated with DCT to alter their properties. DCT treatment has shown to reduce density of defects in crystal structure, increase wear resistance of material, increase hardness, improve toughness, and reduce tensile strength and corrosion resistance. However, some researchers also reported results showing no change in properties (toughness, hardness, corrosion resistance, etc.) or even deterioration when subjected to DCT treatment. This leads to a lack of consistency and reliability of the treatment process, which is needed for successful application in industry. This review provides a synopsis of DCT usage and resulting effects on treated materials used in automotive industry.
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  • 29 Oct 2020
Topic Review
Palm Oil Mill Effluent (POME)
Disposal of palm oil mill effluent (POME), which is highly polluting from the palm oil industry, needs to be handled properly to minimize the harmful impact on the surrounding environment.
  • 7.2K
  • 01 Nov 2021
Topic Review
Courtship
Courtship is the period of development towards an intimate relationship wherein a couple get to know each other and decide if there will be an engagement, followed by a marriage. A courtship may be an informal and private matter between two people or may be a public affair, or a formal arrangement with family approval. Traditionally, in the case of a formal engagement, it is the role of a male to actively "court" or "woo" a female, thus encouraging her to understand him and her receptiveness to a marriage proposal.
  • 7.1K
  • 25 Nov 2022
Topic Review
IBM Mainframe Utility Programs
IBM mainframe utility programs are utility software supplied with IBM mainframe operating systems such as MVS and zOS to carry out various tasks associated with maintenance of the computer system or datasets. The following list describes utilities distributed with OS/360 and successors. No VSE or VM utilities are included.
  • 7.1K
  • 26 Oct 2022
Topic Review
Geodetic Datum
A geodetic datum or geodetic system (also: geodetic reference datum or geodetic reference system) is a coordinate system, and a set of reference points, used for locating places on the Earth (or similar objects). An approximate definition of sea level is the datum WGS 84, an ellipsoid, whereas a more accurate definition is Earth Gravitational Model 2008 (EGM2008), using at least 2,159 spherical harmonics. Other datums are defined for other areas or at other times; ED50 was defined in 1950 over Europe and differs from WGS 84 by a few hundred meters depending on where in Europe you look. Mars has no oceans and so no sea level, but at least two martian datums have been used to locate places there. Datums are used in geodesy, navigation, and surveying by cartographers and satellite navigation systems to translate positions indicated on maps (paper or digital) to their real position on Earth. Each starts with an ellipsoid (stretched sphere), and then defines latitude, longitude and altitude coordinates. One or more locations on the Earth's surface are chosen as anchor "base-points". The difference in co-ordinates between datums is commonly referred to as datum shift. The datum shift between two particular datums can vary from one place to another within one country or region, and can be anything from zero to hundreds of meters (or several kilometers for some remote islands). The North Pole, South Pole and Equator will be in different positions on different datums, so True North will be slightly different. Different datums use different interpolations for the precise shape and size of the Earth (reference ellipsoids). Because the Earth is an imperfect ellipsoid, localised datums can give a more accurate representation of the area of coverage than WGS 84. OSGB36, for example, is a better approximation to the geoid covering the British Isles than the global WGS 84 ellipsoid. However, as the benefits of a global system outweigh the greater accuracy, the global WGS 84 datum is becoming increasingly adopted. Horizontal datums are used for describing a point on the Earth's surface, in latitude and longitude or another coordinate system. Vertical datums measure elevations or depths.
  • 7.1K
  • 24 Nov 2022
Topic Review
Smart Grid Management, Control, and Operation
Smart grid management, control and operation (SGMCO) are key tasks for maintaining their proper functioning as well as for their extension and expansion. The current challenges of power generation, distribution, transmission, and consumption, as well as growing energy demand, facilitate the integration of a large number of smart grids with renewable energy generators and physical information systems, while smart grids are moving toward distribution and decentralization in response to the evolving application of the Internet of Energy (IoE). SGMCO handles not only traditional management, control, and operations, but also the future challenges for smart grids: Collaboration between stakeholders, control of network imbalances (e.g. frequency and voltage regulation), data analysis and management, decentralized network management and operation, and security and privacy.
  • 7.1K
  • 10 Jan 2022
Topic Review
Transmission Electron Microscopy
Transmission electron microscopy (TEM) is a microscopy technique in which a beam of electrons is transmitted through a specimen to form an image. The specimen is most often an ultrathin section less than 100 nm thick or a suspension on a grid. An image is formed from the interaction of the electrons with the sample as the beam is transmitted through the specimen. The image is then magnified and focused onto an imaging device, such as a fluorescent screen, a layer of photographic film, or a sensor such as a scintillator attached to a charge-coupled device. Transmission electron microscopes are capable of imaging at a significantly higher resolution than light microscopes, owing to the smaller de Broglie wavelength of electrons. This enables the instrument to capture fine detail—even as small as a single column of atoms, which is thousands of times smaller than a resolvable object seen in a light microscope. Transmission electron microscopy is a major analytical method in the physical, chemical and biological sciences. TEMs find application in cancer research, virology, and materials science as well as pollution, nanotechnology and semiconductor research, but also in other fields such as paleontology and palynology. TEM instruments have multiple operating modes including conventional imaging, scanning TEM imaging (STEM), diffraction, spectroscopy, and combinations of these. Even within conventional imaging, there are many fundamentally different ways that contrast is produced, called "image contrast mechanisms". Contrast can arise from position-to-position differences in the thickness or density ("mass-thickness contrast"), atomic number ("Z contrast", referring to the common abbreviation Z for atomic number), crystal structure or orientation ("crystallographic contrast" or "diffraction contrast"), the slight quantum-mechanical phase shifts that individual atoms produce in electrons that pass through them ("phase contrast"), the energy lost by electrons on passing through the sample ("spectrum imaging") and more. Each mechanism tells the user a different kind of information, depending not only on the contrast mechanism but on how the microscope is used—the settings of lenses, apertures, and detectors. What this means is that a TEM is capable of returning an extraordinary variety of nanometer- and atomic-resolution information, in ideal cases revealing not only where all the atoms are but what kinds of atoms they are and how they are bonded to each other. For this reason TEM is regarded as an essential tool for nanoscience in both biological and materials fields. The first TEM was demonstrated by Max Knoll and Ernst Ruska in 1931, with this group developing the first TEM with resolution greater than that of light in 1933 and the first commercial TEM in 1939. In 1986, Ruska was awarded the Nobel Prize in physics for the development of transmission electron microscopy.
  • 7.1K
  • 05 Dec 2022
Topic Review
The Genetic Basis of Eye Color
Eye color is a polygenic phenotype, and many genetic variants have been highlighted, with the major contributor being the HERC2-OCA2 locus, where many single nucleotide variations (SNPs) were identified.
  • 7.1K
  • 22 Aug 2023
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