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Topic Review
Wastewater Fecal Pollution Management
Global water scarcity has led to significant dependence on reclaimed or recycled water for potable uses. Effluents arising from human and animal gut microbiomes highly influence water quality. Wastewater pollution is, therefore, frequently monitored using bacterial indicators (BI).
  • 1.9K
  • 16 Dec 2022
Topic Review
5-Aminolevulinic Acid in Photodynamic Therapy
5-Aminolevulinic acid (ALA) is a naturally occurring amino acid synthesized in all nucleated mammalian cells. As a porphyrin precursor, ALA is metabolized in the heme biosynthetic pathway to produce protoporphyrin IX (PpIX), a fluorophore and photosensitizing agent. ALA administered exogenously bypasses the rate-limit step in the pathway, resulting in PpIX accumulation in tumor tissues. Such tumor-selective PpIX disposition following ALA administration has been exploited for tumor fluorescence diagnosis and photodynamic therapy (PDT) with much success. Five ALA-based drugs have now received worldwide approval and are being used for managing very common human (pre)cancerous diseases such as actinic keratosis and basal cell carcinoma or guiding the surgery of bladder cancer and high-grade gliomas, making it the most successful drug discovery and development endeavor in PDT and photodiagnosis. 
  • 1.9K
  • 04 May 2023
Topic Review
Hazards of the Ammonia Bunkering Process
Ammonia is thought to be a potential alternative for hydrogen storage in the future, allowing for CO2-free energy systems. Ammonia’s beneficial characteristics with regard to hydrogen storage include its high volumetric hydrogen density, low storage pressure, and long-term stability. However, ammonia is characterized by toxicity, flammability, and corrosiveness, making safety a challenge compared to other alternative fuels. In specific circumstances, leakage from ammonia bunkering can cause risks, dispersion, and unsafe areas due to its flammability and toxicity. To avoid dispersion, fire, and explosion hazards on ships, it is crucial to conduct thorough risk analyses.
  • 1.9K
  • 30 May 2023
Topic Review
Yellow-throated Marten
The Yellow-throated Marten (Martes flavigula) is a charismatic and agile carnivore native to the forests of Asia, including parts of India, Southeast Asia, and China. With its distinctive yellow throat patch and sleek fur, this arboreal mustelid is known for its elusive nature and remarkable climbing abilities. As a versatile predator, the Yellow-throated Marten preys on a variety of small mammals, birds, insects, and fruits, playing a vital role in forest ecosystems as both a predator and a seed disperser.
  • 1.9K
  • 15 Mar 2024
Topic Review
Biofortification
Biofortification is the process of increasing the number of vitamins and minerals in a crop; it can be carried out via agronomic techniques, transgenic technology, or plant breeding. The most practical and sustainable method for addressing the nutritional issue is biofortification, which involves enhancing the nutrients in common foods. This method is likely to reach rural residents who have limited access to a range of dietary options or other micronutrient therapies by the use of biofortified crops. 
  • 1.9K
  • 21 Jan 2024
Topic Review
Urban Noise and Psychological Distress
Chronic exposure to urban noise is harmful for auditory perception, cardiovascular, gastrointestinal and nervous systems, while also causing psychological annoyance. Around 25% of the EU population experience a deterioration in the quality of life due to annoyance and about 5–15% suffer from sleep disorders, with many disability-adjusted life years (DALYs) lost annually. This entry highlights the main sources of urban noise, the principal clinical disorders and the most effected countries.
  • 1.9K
  • 14 Oct 2020
Topic Review
Nanoparticles in Polyelectrolyte Multilayer LbL
Originally regarded as auxiliary additives, nanoparticles have become important constituents of polyelectrolyte multilayers. They represent the key components to enhance mechanical properties, enable activation by laser light or ultrasound, construct anisotropic and multicompartment structures, and facilitate the development of novel sensors and movable particles.
  • 1.9K
  • 15 May 2021
Topic Review
Supersonic Flow Control
In high-speed fluid dynamics, base pressure controls find many engineering applications, such as in the automobile and defense industries. Several studies have been reported on flow control with sudden expansion duct. 
  • 1.9K
  • 02 Dec 2021
Topic Review
Whey for Bioethanol Production by Yeast
Concerns about fossil fuel depletion and the environmental effects of greenhouse gas emissions have led to widespread fermentation-based production of bioethanol from corn starch or sugarcane. However, competition for arable land with food production has led to the extensive investigation of lignocellulosic sources and waste products of the food industry as alternative sources of fermentable sugars. In particular, whey, a lactose-rich, inexpensive byproduct of dairy production, is available in stable, high quantities worldwide. Therefore, whey is indeed an ideal alternative feedstock for fuel ethanol feedstock because it can provide a remarkable 6–10 million tons of lactose annually. However, despite the availability of this massive, underutilized resource, it faces challenges in being adopted at a commercial scale since S. cerevisiae, the most common fermentative species for transforming sugars to ethanol, lacks the enzyme required for lactose utilization and thus cannot ferment whey into ethanol without further metabolic engineering. 
  • 1.9K
  • 27 Apr 2022
Topic Review
Abusive Domain Names by Internet Entities
A large number of domains are abused every day for cybercrime. At the same time, the fight against abusive domains is not the fight of one person or organization but a battle that requires the cooperation of the entire community.  A large number of domain names on the Internet are misused daily for cybercriminal activities, ranging from spoofing victims’ private information (phishing), to maliciously installing software onto end-users’ devices (malware attacks), to distributing illegal obscene videos. Internet abuse continues to victimize millions of people each year, reducing trust in the Internet as a place to conduct business and non-business activities. This decline in confidence has a detrimental effect on all stakeholders in the Internet ecosystem, from end-users to infrastructure service providers.
  • 1.9K
  • 06 May 2022
Topic Review
Healing Performance Assessment of Concrete Using Machine Learning
Bacterial-based self-healing concrete (BSHC) is a well-known healing technology which has been investigated for a few decades for its excellent crack healing capacity. The healing performance (HP) of BSHC can be predicted using machine learning (ML) approaches to save the time and cost of laboratory tests, bacteria selection and healing mechanisms adoption. 
  • 1.9K
  • 12 Jul 2022
Topic Review
Black Locust (Robinia pseudoacacia L.) in Romanian Forestry
Black locust (Robinia pseudoacacia L.) is a North American species that was introduced in Romania around the end of the 17th century, and it was first used in large-scale afforestation of degraded lands in the year 1852. Due to its remarkable adaptability, fast growth, and vigorous sprouting capacity, it has become one of the most widely spread exotic species in Romania. Using black locust for afforestation, Romanian foresters successfully reclaimed large areas of abandoned agricultural land degraded by “flying sands” in southwest of the country, thus contributing to mitigation of the aridization phenomena. Driving the extensive use of the species was its durable and versatile wood, much appreciated by rural communities, complemented with major benefits from crop fields and settlement protection against wind/sand deflation, as well as economically viable byproducts. In addition to the immediate improvements to local microclimate, afforestations also contributed to long-term climate change mitigation by sequestering atmospheric CO2 in the carbon pools (living tree biomass, soil organic matter, litter) as well as downstream wood products (e.g., furniture). Nevertheless, in the past decade, awareness has been raised towards its invasive potential in protected areas.
  • 1.9K
  • 26 Oct 2022
Topic Review
Methods to Remediate Arsenic-Contaminated Soils
Arsenic is a metalloid widely distributed in the environment and of global concern for human health. In a promising breakthrough for sustainable arsenic soil remediation, a fern, Pteris vittata L., was discovered to take up arsenic from the soil and accumulate it in its fronds at up to ~100 times soil concentrations. Successively harvesting the fronds removes, or phytoextracts, arsenic from the soil with potential environmental and economic benefits including low site disturbance and low cost. 
  • 1.9K
  • 16 Jan 2023
Topic Review
Industry 4.0 and Sustainable development
The text provides a methodologically coherent analysis of technological development in the context of the fourth industrial revolution or Industry 4.0 and its impact on changes in sustainable development policy. The focus is on topics that are directly relevant to current sustainable business development and the promotion of research and development of clean and smart technologies and processes
  • 1.9K
  • 04 Apr 2021
Topic Review
Hyaluronic Acid for Tissue Engineering
Polysaccharides such as hyaluronic acid (HA) which is omnipresent in the human body and exert pleiotropic biological functions such as tissue repair and tissue regeneration, may be exploited for cosmetics development, esthetic medicine, tissue engineering and regenerative medicine. In this work, the authors describe the excellent biocompatibility and biodegradability of HA-derived hydrogels with make them ideal materials for tissue engineering applications.
  • 1.9K
  • 27 May 2021
Topic Review
Immunomodulatory Effects of Dietary Polyphenols
Functional and nutraceutical foods provide an alternative way to improve immune function to aid in the management of various diseases. With the development of research into nutraceuticals, dietary polyphenols are getting attention due to their immunomodulatory role. There is evidence that dietary polyphenols can influence dendritic cells, have an immunomodulatory effect on macrophages, increase proliferation of B cells, T cells, and suppress Type 1 T helper (Th1), Th2, Th17, and Th9 cells. Further, polyphenols have a beneficial role in the prevention and treatment of inflammatory bowel disease, allergy, asthma, and auto-immune diseases (type 1 diabetes, rheumatoid arthritis, and multiple sclerosis).
  • 1.9K
  • 16 Mar 2021
Topic Review
Psychodynamic Psychotherapy
Psychodynamic psychotherapy or psychoanalytic psychotherapy is a form of depth psychology, the primary focus of which is to reveal the unconscious content of a client's psyche in an effort to alleviate psychic tension. It evolved from and largely replaced psychoanalysis in the mid-20th century. Psychodynamic psychotherapy relies on the interpersonal relationship between client and therapist more than other forms of depth psychology. In terms of approach, this form of therapy uses psychoanalysis adapted to a less intensive style of working, usually at a frequency of once or twice per week. Principal theorists drawn upon are Freud, Klein, and theorists of the object relations movement, e.g., Winnicott, Guntrip, and Bion. Some psychodynamic therapists also draw on Jung or Lacan or Langs. It is a focus that has been used in individual psychotherapy, group psychotherapy, family therapy, and to understand and work with institutional and organizational contexts. In psychiatry, it is has been used for adjustment disorders, as well as posttraumatic stress disorder (PTSD) but more often for personality-related disorders.
  • 1.9K
  • 29 Sep 2022
Topic Review
Flocking (Behavior)
thumb|200px|right|A swarm-like flock of starlings Flocking behavior is the behavior exhibited when a group of birds, called a flock, are foraging or in flight. There are parallels with the shoaling behavior of fish, the swarming behavior of insects, and herd behavior of land animals. During the winter months, Starlings are known for aggregating into huge flocks of hundreds to thousands of individuals, murmurations, which when they take flight altogether, render large displays of intriguing swirling patterns in the skies above observers. Computer simulations and mathematical models which have been developed to emulate the flocking behaviors of birds can also generally be applied to the "flocking" behavior of other species. As a result, the term "flocking" is sometimes applied, in computer science, to species other than birds. This article is about the modelling of flocking behavior. From the perspective of the mathematical modeller, "flocking" is the collective motion by a group of self-propelled entities and is a collective animal behavior exhibited by many living beings such as birds, fish, bacteria, and insects. It is considered an emergent behavior arising from simple rules that are followed by individuals and does not involve any central coordination. Flocking behavior was simulated on a computer in 1987 by Craig Reynolds with his simulation program, Boids. This program simulates simple agents (boids) that are allowed to move according to a set of basic rules. The result is akin to a flock of birds, a school of fish, or a swarm of insects.
  • 1.9K
  • 27 Oct 2022
Topic Review
Effect of a Vegan Diet on Alzheimer’s Disease
A vegan diet tends to be plant-based, but plant-based diets are not vegan by definition. Regarding Alzheimer’s disease (AD) prevention, a vegan diet includes low levels of saturated fats and cholesterol, contributing to a healthy blood lipid profile. 
  • 1.9K
  • 20 Dec 2022
Topic Review
Molecular Mechanisms behind Muscles Growth in Young Subjects
Muscle growth, or muscle hypertrophy, is a complex process regulated by several molecular pathways. The IGF-1/PI3K/Akt/mTOR pathway is a vital signaling cascade in muscle growth that involves various interconnected mechanisms. Its activation increases protein synthesis, reduces protein degradation, and improves cell growth. Akt activation is crucial in promoting muscle protein synthesis in response to exercise and nutrient intake in young individuals. The timing of exercise and protein intake also affect Akt activation and subsequent muscle protein synthesis. While exercise alone did not increase Akt and mTOR phosphorylation, protein ingestion afterward did so in a dose-dependent manner. Growth hormone (GH) promotes the uptake of essential nutrients, such as glucose and amino acids, into muscle cells for energy production and protein synthesis. Testosterone is one of the most potent naturally secreted androgenic-anabolic hormones, and its biological effects include promoting muscle growth. 
  • 1.9K
  • 30 Oct 2023
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