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Topic Review
Design and Development of Novel Nutraceuticals
The global prevalence of nutraceuticals is reflected in the increasing number of commercially available nutraceuticals and their wide range of applications. Therefore, a unique opportunity emerges for their further exploration using innovative, reliable, accurate, low cost, and high hit rate methods to design and develop next generation nutraceuticals. Towards this direction, computational techniques constitute an influential trend for academic and industrial research, providing not only the chemical tools necessary for further mechanism characterization but also the starting point for the development of novel nutraceuticals. 
  • 1.9K
  • 27 May 2022
Topic Review
Post-Mortem Dental Profile in Animal Forensic Investigations
Veterinary forensics is becoming more important in our society as a result of the growing demand for investigations related to crimes against animals or investigations of criminal deaths caused by animals. A veterinarian may participate as an expert witness or may be required to give forensic assistance, by providing knowledge of the specialty to establish a complete picture of the involvement of an animal and allowing the Courts to reach a verdict. By applying diverse dental profiling techniques, not only can species, sex, age-at-death, and body size of an animal be estimated, but also data about their geographical origin (provenance) and the post-mortem interval.
  • 1.9K
  • 29 Aug 2022
Topic Review
Psychodynamic Psychotherapy
Psychodynamic psychotherapy or psychoanalytic psychotherapy is a form of depth psychology, the primary focus of which is to reveal the unconscious content of a client's psyche in an effort to alleviate psychic tension. It evolved from and largely replaced psychoanalysis in the mid-20th century. Psychodynamic psychotherapy relies on the interpersonal relationship between client and therapist more than other forms of depth psychology. In terms of approach, this form of therapy uses psychoanalysis adapted to a less intensive style of working, usually at a frequency of once or twice per week. Principal theorists drawn upon are Freud, Klein, and theorists of the object relations movement, e.g., Winnicott, Guntrip, and Bion. Some psychodynamic therapists also draw on Jung or Lacan or Langs. It is a focus that has been used in individual psychotherapy, group psychotherapy, family therapy, and to understand and work with institutional and organizational contexts. In psychiatry, it is has been used for adjustment disorders, as well as posttraumatic stress disorder (PTSD) but more often for personality-related disorders.
  • 1.9K
  • 29 Sep 2022
Topic Review
Wegman Report
The Wegman Report (officially called the Ad Hoc Committee Report on the 'Hockey Stick' Global Climate Reconstruction) was prepared in 2006 by three statisticians led by Edward Wegman at the request of Rep. Joe Barton of the United States House Committee on Energy and Commerce to validate criticisms made by Stephen McIntyre and Ross McKitrick of reconstructions of the temperature record of the past 1000 years, in particular the reconstructions by Mann, Bradley and Hughes which had become the focus of the hockey stick controversy.
  • 1.9K
  • 08 Nov 2022
Topic Review
5-Aminolevulinic Acid in Photodynamic Therapy
5-Aminolevulinic acid (ALA) is a naturally occurring amino acid synthesized in all nucleated mammalian cells. As a porphyrin precursor, ALA is metabolized in the heme biosynthetic pathway to produce protoporphyrin IX (PpIX), a fluorophore and photosensitizing agent. ALA administered exogenously bypasses the rate-limit step in the pathway, resulting in PpIX accumulation in tumor tissues. Such tumor-selective PpIX disposition following ALA administration has been exploited for tumor fluorescence diagnosis and photodynamic therapy (PDT) with much success. Five ALA-based drugs have now received worldwide approval and are being used for managing very common human (pre)cancerous diseases such as actinic keratosis and basal cell carcinoma or guiding the surgery of bladder cancer and high-grade gliomas, making it the most successful drug discovery and development endeavor in PDT and photodiagnosis. 
  • 1.9K
  • 04 May 2023
Topic Review
Pharmacological Activities of E. ferox
Euryale ferox Salisb. (prickly water lily) is the only extent of the genus Euryale that has been widely distributed in China, India, Korea, and Japan. The seeds of E. ferox (EFS) have been categorized as superior food for 2000 years in China, based on their abundant nutrients including polysaccharides, polyphenols, sesquineolignans, tocopherols, cyclic dipeptides, glucosylsterols, cerebrosides, and triterpenoids. These constituents exert multiple pharmacological effects, such as antioxidant, hypoglycemic, cardioprotective, antibacterial, anticancer, antidepression, and hepatoprotective properties. 
  • 1.9K
  • 01 Jun 2023
Topic Review
Kaempferol- and Quercetin-Rich Herbs in Alzheimer’s Disease Treatment
Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder impairing cognition and memory in the elderly. This disorder has a complex etiology, including senile plaque and neurofibrillary tangle formation, neuroinflammation, oxidative stress, and damaged neuroplasticity. The treatment options are limited, so alternative treatments such as herbal medicine could suppress symptoms while slowing cognitive decline.
  • 1.9K
  • 02 Jan 2024
Topic Review
Yellow-throated Marten
The Yellow-throated Marten (Martes flavigula) is a charismatic and agile carnivore native to the forests of Asia, including parts of India, Southeast Asia, and China. With its distinctive yellow throat patch and sleek fur, this arboreal mustelid is known for its elusive nature and remarkable climbing abilities. As a versatile predator, the Yellow-throated Marten preys on a variety of small mammals, birds, insects, and fruits, playing a vital role in forest ecosystems as both a predator and a seed disperser.
  • 1.9K
  • 15 Mar 2024
Topic Review Peer Reviewed
Electronic Textiles
Electronic textiles belong to the broader range of smart (or “intelligent”) textiles. Their “smartness” is enabled by embedded or added electronics and allows the sensing of defined parameters of their environment as well as actuating according to these sensor data. For this purpose, different sensors (e.g., temperature, strain, light sensors) and actuators (e.g., LEDs or mechanical actuators) are embedded and connected with a power supply, a data processor, and internal/external communication. 
  • 1.9K
  • 13 Apr 2022
Topic Review
Amaryllidaceae Alkaloids
Alkaloids are an important group of specialized nitrogen metabolites with a wide range of biochemical and pharmacological effects. Since the first publication on lycorine in 1877, more than 650 alkaloids have been extracted from Amaryllidaceae bulbous plants and clustered together as the Amaryllidaceae alkaloids (AAs) family. 
  • 1.9K
  • 31 May 2021
Topic Review
Persufflation (PSF)
Persufflation (PSF) utilises the organ's own vascular network to provide oxygen to the organ tissue and maintain metabolism during preservation to avoid hypoxic damage. This method discovered in the early 20th century has shown promise in providing both longer-term preservation and organ reconditioning capabilities for multiple organs including the liver, kidneys, and pancreas.
  • 1.9K
  • 11 Nov 2021
Topic Review
Impact Assessment in Information Security Management Systems
Organizations must be committed to ensuring the confidentiality, availability, and integrity of the information in their possession to manage legal and regulatory obligations and to maintain trusted business relationships. Information security management systems (ISMSs) support companies to better deal with information security risks and cyber-attacks. Although there are many different approaches to successfully implementing an ISMS in a company, the most important and time-consuming part of establishing an ISMS is a risk assessment.
  • 1.9K
  • 03 Mar 2022
Topic Review
The CRISPR-Cas System
CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) represents a powerful genome editing technology that revolutionized in a short period of time numerous natural sciences branches. Therefore, extraordinary progress was made in various fields, such as entomology or biotechnology. 
  • 1.9K
  • 18 Apr 2022
Topic Review
Cellular Communication
Cellular communication is an umbrella term used in biology and more in depth in biophysics, biochemistry and biosemiotics to identify different types of communication methods between living cellulites. Some of the methods include cell signaling among others. This process allows millions of cells to communicate and work together to perform important bodily processes that are necessary for survival. Both multicellular and unicellular organisms heavily rely on cell-cell communication.
  • 1.9K
  • 24 Oct 2022
Topic Review
Effect of a Vegan Diet on Alzheimer’s Disease
A vegan diet tends to be plant-based, but plant-based diets are not vegan by definition. Regarding Alzheimer’s disease (AD) prevention, a vegan diet includes low levels of saturated fats and cholesterol, contributing to a healthy blood lipid profile. 
  • 1.9K
  • 20 Dec 2022
Topic Review
Fermented Vegetables
Fermentation is a traditional method used to preserve vegetables. Many regions worldwide have a tradition of consuming fermented vegetables. Numerous fermented vegetables exist according to the raw materials, formula, and fermentation technologies used. Typical fermented vegetables include sauerkraut, paocai, zhacai, and kimchi. The primary constituents for producing fermented vegetables are cruciferous vegetables, such as cabbage, kale, mustard green, or radish. Other prevalent vegetables include chili pepper, lotus root, carrot, ginger, cucumber, eggplant, beetroot, garlic, olive, papaya, and chayote. There are variations in the production procedures used for different fermented vegetables. 
  • 1.9K
  • 03 Jan 2024
Topic Review
Biomarkers of Acute Kidney Injury
Acute kidney injury (AKI) remains a complex challenge with diverse underlying pathological mechanisms and etiologies. The clinical applications of AKI biomarkers are becoming extensive and serving as relevant tools in distinguishing acute tubular necrosis from other acute renal conditions. Also, these biomarkers can offer significant insights into the risk of progression to chronic kidney disease (CKD) and in the context of kidney transplantation.
  • 1.9K
  • 15 Apr 2024
Topic Review
Health and Oral Health Coaching
Health-related behavior based on diet is an important determinant of oral health in independent elderly. Aging impairs senses, mastication, oral status, and function, causing nutritional needs and diet insufficiencies that contribute to a vicious circle of impairment. But the present needs of independent older adults suggest that health research and oral health care should shift from disease management and therapy to integral customized and personal treatment plans, including lifestyle, psychological, nutritional, and oral health coaching approaches. In this paper health coaching approaches in medical and dental settings are valued as to their effectiveness for older adults. Furthermore, coaching approaches for seniors are discussed and coaching models for better senior patient-dentist cooperation on the diet issue are suggested. Diet and oral health coaching is proven to be a modern senior patient-centered approach that needs to be incorporated at all relevant settings. It should aim to empower older adults in co-management of their oral diseases or bad diet habits affecting their oral health. This can be carried out through an incorporated educational plan for dentists either at the postgraduate or professional level since advantages seem to enhance the quality of life of the independent elderly.
  • 1.9K
  • 31 Jan 2022
Topic Review
Semaphorins Effects in Metabolic Disorders
       Semaphorins are a family originally identified as axonal guidance molecules. They are also involved in tumor growth, angiogenesis, immune regulation, as well as other biological and pathological processes. Recent studies have shown that semaphorins play a role in metabolic diseases including obesity, adipose inflammation, and diabetic complications, including diabetic retinopathy, diabetic nephropathy, diabetic neuropathy, diabetic wound healing, and diabetic osteoporosis. Evidence provides mechanistic insights regarding the role of semaphorins in metabolic diseases by regulating adipogenesis, hypothalamic melanocortin circuit, immune responses, and angiogenesis. In this review, we summarize recent progress regarding the role of semaphorins in obesity, adipose inflammation, and diabetic complications.
  • 1.9K
  • 28 Aug 2020
Topic Review
Nanoparticles in Polyelectrolyte Multilayer LbL
Originally regarded as auxiliary additives, nanoparticles have become important constituents of polyelectrolyte multilayers. They represent the key components to enhance mechanical properties, enable activation by laser light or ultrasound, construct anisotropic and multicompartment structures, and facilitate the development of novel sensors and movable particles.
  • 1.9K
  • 15 May 2021
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