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Topic Review
Development and Application of Underground Intelligent Load-Haul-Dump Vehicle
Load-haul-dump vehicle (LHD) is an important and necessary piece of mining equipment, which plays a key role in the transportation of underground ores. Traditional LHD vehicles usually complete ore shoveling, transporting and unloading through manual operation.
  • 1.9K
  • 27 Sep 2022
Topic Review
Chronic High Fructose Intake in Beverages and SARS-CoV-2
Fructose intake from SSBs increased during the COVID-19 lockdown. Chronic high intake of fructose activates several damage-associated processes of lung injury, including renin-angiotensin system (RAS) activation, uric acid (UA) levels, aldose reductase (AR) activity, and advanced glycation end products (AGEs) production. These molecular mechanisms are involved in lung injury induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. 
  • 1.9K
  • 12 Jan 2023
Topic Review
Applications of Chitosan
Public health, production and preservation of food, development of environmentally friendly (cosmeto-)textiles and plastics, synthesis processes using green technology, and improvement of water quality, among other domains, can be controlled with the help of chitosan. This aminopolysaccharide is recognized as safe and produced from an abundant and renewable source (chitin). Chitosan exhibits advantageous properties, such as biocompatibility, biodegradability, antimicrobial effect, mucoadhesive properties, film-forming capacity, elicitor of plant defenses, coagulant-flocculant ability, synergistic effect and adjuvant along with other substances and materials. In part, its versatility is attributed to the presence of ionizable and reactive primary amino groups that provide strong chemical interactions with small inorganic and organic substances, macromolecules, ions, and cell membranes/walls. Hence, chitosan has been used either to create new materials or to modify the properties of conventional materials applied on an industrial scale.
  • 1.9K
  • 03 Feb 2023
Topic Review
Urban Archetypes
To make cities more sustainable and livable and to achieve climate targets in transportation, cities around the globe must undergo sustainable transformations. However, disparities in initial conditions pose challenges when trying to implement these sustainable changes. Identifying these differences aids in the comprehension of future developments. Urban archetypes represent a typification of cities in order to investigate mobility-related homogeneity between cities.
  • 1.9K
  • 27 Nov 2023
Topic Review
Manganese and Manganese Oxide Nanoparticles
Manganese and its oxides in the form of nanoparticles could be a promising alternative for gadolinium-based contrast agents used in diagnostic imaging. Manganese, which is essential for living organisms as an enzyme cofactor, under excessive exposure—for example, due to water contamination or as an occupational hazard for welders—can lead to neurological disorders, including manganism—a condition similar to Parkinson’s disease. This review attempts to summarise the available literature data on the potential applications of manganese and manganese oxide nanoparticles.
  • 1.9K
  • 18 May 2021
Topic Review
Soil as a Biological System
I have summarized the in issues discussed in the mini review that I have published in 2020. Starting from the seven grand questions described by Selman Waksman in 1927 I have discussed the main known aspects of soil as a biological system, the main research approaches and one knowledge gap for each question.
  • 1.9K
  • 10 Jul 2020
Topic Review
Pluripotent Stem Cell
Pluripotent stem cells (PSC) such as embryonic stem cells (ESC) and induced PSCs (iPSC) are originated from embryos and induced from adult tissue cells, respectively. PSCs are capable of proliferating almost indefinitely, and differentiating into all somatic cells, through processes that mimic early embryogenesis. The resulting cells tend to carry embryonic characteristics.
  • 1.9K
  • 11 Oct 2021
Topic Review
High Performance Bioplastics
Biomass provides a wealth of renewable and bio-waste resources for bioplastics synthesis. Many of these bio-based plastics, encompass capacities for biodegradation and bioprocessing with high performance features akin to petroleum-based plastics. The realisation of bioplastics that exhibit a complete set of mechanical and biodegradability, hold the promise of delivering material of ecologically sustainable, low carbon footprint circularity.
  • 1.9K
  • 14 Jul 2021
Topic Review
VR/AR in K-12 Science Education
virtual reality (VR) and augmented reality (AR) are increasingly capturing educators’ and learners’ attention. In particular, VR is defined as a real-time graphical simulation in which the user interacts with the system via analog control, within a spatial frame of reference and with user control of the viewpoint’s motion and view direction. It first appeared in 1966 and was used in the design of US Air Force Flight Simulator. Developed from VR, AR is a technology used for improving users’ perception of the real world by dynamically adding virtual elements to the physical environment. It made its debut in the 1990s, which was initially proposed by scientists from Boeing, an aircraft manufacturer, where they mixed virtual graphics with real environment displays to help aircraft electricians assemble cables.
  • 1.9K
  • 08 Dec 2021
Topic Review
Hypothermia Caused by Earthquakes
Natural disasters can destroy all personal belongings and infrastructure and can deprive humans of the possibility of protecting themselves from harsh environments. One consequence may be death from accidental hypothermia.
  • 1.9K
  • 11 Mar 2022
Topic Review
Transmission Electron Microscopy DNA Sequencing
Transmission electron microscopy DNA sequencing is a single-molecule sequencing technology that uses transmission electron microscopy techniques. The method was conceived and developed in the 1960s and 70s, but lost favor when the extent of damage to the sample was recognized. In order for DNA to be clearly visualized under an electron microscope, it must be labeled with heavy atoms. In addition, specialized imaging techniques and aberration corrected optics are beneficial for obtaining the resolution required to image the labeled DNA molecule. In theory, transmission electron microscopy DNA sequencing could provide extremely long read lengths, but the issue of electron beam damage may still remain and the technology has not yet been commercially developed.
  • 1.9K
  • 31 Oct 2022
Topic Review
Scientist.com
Scientist.com (formerly known as Assay Depot) is a network of public and private e-commerce marketplaces that connect buyers and sellers of scientific research services. The company was founded in 2007 by Kevin Lustig, Chris Petersen and Andrew Martin and launched its first public research marketplace in September 2008.
  • 1.9K
  • 18 Nov 2022
Topic Review
Extracellular Hemoglobin
Hemoglobin is essential for maintaining cellular bioenergetic homeostasis through its ability to bind and transport oxygen to the tissues. Besides its ability to transport oxygen, hemoglobin within erythrocytes plays an important role in cellular signaling and modulation of the inflammatory response either directly by binding gas molecules (NO, CO, and CO2) or indirectly by acting as their source. Once hemoglobin reaches the extracellular environment, it acquires several secondary functions affecting surrounding cells and tissues. By modulating the cell functions, this macromolecule becomes involved in the etiology and pathophysiology of various diseases. The up-to-date results disclose the impact of extracellular hemoglobin on (i) redox status, (ii) inflammatory state of cells, (iii) proliferation and chemotaxis, (iv) mitochondrial dynamic, (v) chemoresistance and (vi) differentiation.
  • 1.9K
  • 06 Dec 2022
Topic Review
Industry Guidance on Pipeline Integrity Management
For operators of oil and gas to save the cost of unforeseen events and risks, and to avoid unnecessary shutdowns, there is a need to have an effective subsea pipeline integrity management system. Currently a large number of subsea pipelines around the globe have already exceeded their design lives; nevertheless, they are still being operated safely, effectively and with diligent consideration towards Environmental, Health and Safety regulations, as well as international standards and best practices. In addition, many older flowlines have no permanent pigging facilities due to various design and operational limitations. For the unpiggable pipeline, the vast majority of the oil and gas operators use different inspection and monitoring techniques to provide essential integrity management data such as product chemistry, cathodic protection, electrical resistance probes and coupons, etc. However, translating such essential integrity management data into meaningful information to make crucial integrity-based decisions can be challenging.
  • 1.9K
  • 10 Jan 2023
Topic Review
Yeast-Based Virus-like Particles
Virus-like particles (VLPs) are empty, nanoscale structures morphologically resembling viruses. Internal cavity, noninfectious, and particulate nature with a high density of repeating epitopes, make them an ideal platform for vaccine development and drug delivery. 
  • 1.9K
  • 11 Apr 2023
Topic Review
Plant Pathogen Detection with Nanotechnology
It is crucial to increase agricultural yields to fulfill the rising demand for food and the security it provides for a growing population. To protect human food supplies and agricultural outputs, disease management is essential. Plant infections are a silent enemy of economic crop production and cross-border commerce of agricultural goods, inflicting roughly 20–30% losses a year. If infections are accurately and rapidly detected and identified, this can be minimized, and specialized treatment can be given. 
  • 1.9K
  • 08 Oct 2023
Topic Review
Overview of Extracellular Polymeric Substances
Extracellular polymeric substances (EPS) are complex extracellular polymers with high molecular weight, which are metabolic products of microorganisms and result from effluent organic matter and microbial lysis or hydrolysis. EPS were proved to have the ability to absorb and biodegrade certain substances. The main components in EPS were found to influence the properties of microbial floccules, such as transfer, surface hydrophilicity/hydrophobicity, and aggregate stability. 
  • 1.9K
  • 17 Oct 2022
Topic Review
Poly(Ionic Liquid) Materials-Based Advanced Formulations for Additive Manufacturing
Innovation in materials specially formulated for additive manufacturing is of great interest and can generate new opportunities for designing cost-effective smart materials for next-generation devices and engineering applications. Nevertheless, advanced molecular and nanostructured systems are frequently not possible to integrate into 3D printable materials, thus limiting their technological transferability. In some cases, this challenge can be overcome using polymeric macromolecules of ionic nature, such as polymeric ionic liquids (PILs). Due to their tuneability, wide variety in molecular composition, and macromolecular architecture, they show a remarkable ability to stabilize molecular and nanostructured materials. The technology resulting from 3D-printable PIL-based formulations represents an untapped array of potential applications, including optoelectronic, antimicrobial, catalysis, photoactive, conductive, and redox applications.
  • 1.9K
  • 08 Dec 2022
Topic Review
Neutrophil Apoptosis as A Powerful Anti-Inflammatory Signal
Neutrophils are highly abundant circulating leukocytes that are amongst the first cells to be recruited to sites of infection or sterile injury. Their ability to generate and release powerful cytotoxic products ties with their role in host defence from bacterial and fungal infections. Neutrophilic inflammation is tightly regulated to limit the amount of ‘bystander injury’ caused. Neutrophils were in the past regarded as short-lived, indiscriminate killers of invading microorganisms. Neutrophils are recognised to also have important anti-inflammatory functions that are critical for the resolution of inflammation and return to homeostasis.
  • 1.9K
  • 30 Dec 2022
Topic Review
Adversarial Machine Learning Attacks against Intrusion Detection Systems
Concerns about cybersecurity and attack methods have risen in the information age. Many techniques are used to detect or deter attacks, such as intrusion detection systems (IDSs), that help achieve security goals, such as detecting malicious attacks before they enter the system and classifying them as malicious activities. However, the IDS approaches have shortcomings in misclassifying novel attacks or adapting to emerging environments, affecting their accuracy and increasing false alarms. To solve this problem, researchers have recommended using machine learning approaches as engines for IDSs to increase their efficacy. Machine-learning techniques are supposed to automatically detect the main distinctions between normal and malicious data, even novel attacks, with high accuracy. However, carefully designed adversarial input perturbations during the training or testing phases can significantly affect their predictions and classifications. Adversarial machine learning (AML) poses many cybersecurity threats in numerous sectors that use machine-learning-based classification systems, such as deceiving IDS to misclassify network packets.
  • 1.9K
  • 09 Mar 2023
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