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Topic Review
Governing Passenger Ship Evacuation
Within the expansive domain of maritime safety, optimizing evacuation procedures stands as a critical endeavour. After all, evacuation is literally the last and fundamental safety level afforded to mariners and passengers. 
  • 2.1K
  • 23 Feb 2024
Topic Review
Japan’s Commercial Real Estate
Japan commercial real estate investment market has, in general, seen a number of scholarly papers in the past, they are concentrated largely on its listed real estate investment segment. There is a significant knowledge gap concerning the non-listed value-add real estate funds’ risk-adjusted performance and portfolio diversification benefits in an institutional investors’ portfolio. This is particularly true in the case of specific countries e.g. in Japan.
  • 2.1K
  • 10 May 2022
Topic Review
Photocatalytic Activity of Cobalt-Based Metal–Organic Frameworks
Nowadays, materials with great potential for environmental protection are being sought. Metal–organic frameworks, in particular those with cobalt species as active sites, have drawn considerable interest due to their excellent properties. With the use of Co-based metal–organic frameworks (MOFs) as photocatalysts in reactions (dye degradation, water oxidation and splitting, carbon dioxide reduction, in addition to the oxidation of organic compounds), even over 90% degradation efficiencies of various dyes (e.g., methylene blue) can be achieved. 
  • 2.1K
  • 18 Apr 2022
Topic Review
Safety and Barriers
The Architecture, Engineering, and Construction (AEC) industry is one of the most dangerous industries due to its unique nature. Safety is a critical issue in developed and developing countries.  Barriers that hinder the implementation of safety in projects and ways to improve safety performance was illustrated in this entry.
  • 2.1K
  • 20 Apr 2021
Topic Review
Receptor Tyrosine Kinases
The receptor tyrosine kinases (RTKs) are a large family of cell-surface receptors, which are essential components of signal transduction pathways. There are more than fifty human RTKs that can be grouped into multiple RTK subfamilies. RTKs mediate cellular signaling transduction, and they play important roles in the regulation of numerous cellular processes. The dysregulation of RTK signaling is related to various human diseases, including cancers. The proteolytic cleavage phenomenon has frequently been found among multiple receptor tyrosine kinases. More and more information about proteolytic cleavage in RTKs has been discovered, providing rich insight.
  • 2.1K
  • 16 May 2021
Topic Review
Biobeneficiation of PGMs
Conventional beneficiation of the Platinum Group of Metals (PGMs) relies on the use of inorganic chemicals. With the depreciation of high grade deposits, these conventional processes are becoming less economically viable. Furthermore, the use of chemicals has serious negative impacts on the environment. To address the challenges of conventional PGM beneficiation, biobeneficiation has been proposed. Bio-beneficiation is the concentration of mineral species by employing microorganisms that interact with either the gangue or the valuable mineral species. Bio-beneficiation can also be described as the use of microorganisms to interact with minerals to subsequently induce processes such as magnetic separation, flotation, and flocculation.
  • 2.1K
  • 19 Jan 2022
Topic Review
Transposon
Transposons are sequences of DNA that can move around to different positions within the genome of a single cell, a process called transposition. In the process, they can cause mutations and change the amount of DNA in the genome. Transposons are also called "jumping genes" or "mobile genetic elements". Discovered by Barbara McClintock early in her career, the topic went on to be a Nobel winning work in 1983. There are a variety of mobile genetic elements, and they can be grouped based on their mechanism of transposition. Class I mobile genetic elements, or retrotransposons, move in the genome by being transcribed to RNA and then back to DNA by reverse transcriptase, while class II mobile genetic elements move directly from one position to another within the genome using a transposase to "cut and paste" them within the genome. Transposons are very useful to researchers as a means to alter DNA inside of a living organism. Transposons make up a large fraction of genome sizes which is evident through the C-values of eukaryotic species. As an example about 45% of the human genome is composed of transposons and their defunct remnants.
  • 2.1K
  • 23 Nov 2022
Topic Review
Mobile Phone Tracking
Mobile phone tracking is a process for identifying the location of a mobile phone, whether stationary or moving. Localization may be effected by a number of technologies, such as using multilateration of radio signals between (several) cell towers of the network and the phone, or simply using GPS. To locate a mobile phone using multilateration of radio signals, it must emit at least the idle signal to contact the next nearby antenna tower, but the process does not require an active call. The Global System for Mobile Communications (GSM) is based on the phone's signal strength to nearby antenna masts. Mobile positioning may include location-based services that disclose the actual coordinates of a mobile phone, which is a technology used by telecommunication companies to approximate the location of a mobile phone, and thereby also its user.
  • 2.1K
  • 02 Dec 2022
Topic Review
Evolution of Personal Data Store
The idea of the personal data store goes back to the early 2000s. The initial idea of this concept was to store and capture digital materials (e.g., books, photos, and other digital documents). This idea was developed for MyLifeBits as a platform to store scanned paper files and record, store, and access a personal lifetime archive. Personal web observatories are another concept based on the idea of Personal Data Stores (PDS). A personal web observatory is a technical platform that, first and foremost, enables individuals to consolidate and archive their data that is dispersed among multiple sources. Later, the concept of Personal Information Management (PIM) and Personal dataspace management was introduced to specifically focus on the process of managing personal digital information such as emails, images, HTML, XML, audio, video, and so on.
  • 2.1K
  • 08 May 2023
Topic Review
Human Dental Pulp Stem Cells
Human dental pulp stem cells (hDPSCs) are adult mesenchymal stem cells (MSCs) obtained from dental pulp and derived from the neural crest. They can differentiate into odontoblasts, osteoblasts, chondrocytes, adipocytes and nerve cells, and they play a role in tissue repair and regeneration.
  • 2.1K
  • 29 May 2023
Topic Review
Bartter and Gitelman Syndromes
Gitelman and Bartter syndromes are rare inherited diseases that belong to the category of renal tubulopathies. The genes associated with these pathologies encode electrolyte transport proteins located in the nephron, particularly in the Distal Convoluted Tubule and Ascending Loop of Henle. Therefore, both syndromes are characterized by alterations in the secretion and reabsorption processes that occur in these regions. Patients suffer from deficiencies in the concentration of electrolytes in the blood and urine, which leads to different systemic consequences related to these salt-wasting processes. The main clinical features of both syndromes are hypokalemia, hypochloremia, metabolic alkalosis, hyperreninemia and hyperaldosteronism. Despite having a different molecular etiology, Gitelman and Bartter syndromes share a relevant number of clinical symptoms, and they have similar therapeutic approaches. The main basis of their treatment consists of electrolytes supplements accompanied by dietary changes. Specifically for Bartter syndrome, the use of non-steroidal anti-inflammatory drugs is also strongly supported. 
  • 2.1K
  • 29 Oct 2021
Topic Review
Pudú
The pudus (Mapudungun püdü or püdu, Spanish: pudú, Spanish pronunciation: [puˈðu]) are two species of South American deer from the genus Pudu, and are the world's smallest deer. The name is a loanword from Mapudungun, the language of the indigenous Mapuche people of central Chile and south-western Argentina. The two species of pudus are the northern pudu (Pudu mephistophiles) from Venezuela, Colombia, Ecuador, and Peru, and the southern pudu (Pudu puda; sometimes incorrectly modified to Pudu pudu) from southern Chile and south-western Argentina . Pudus range in size from 32 to 44 centimeters (13 to 17 in) tall, and up to 85 centimeters (33 in) long. The southern pudu is currently classified as near threatened, while the northern pudu is classified as Data Deficient in the IUCN Red List.
  • 2.1K
  • 22 Nov 2022
Topic Review
Expression, Regulation, and Physiological Relevance of Skin Aquaporins
The skin is the largest organ of the human body, serving as an effective mechanical barrier between the internal milieu and the external environment. The skin is widely considered the first-line defence of the body, with an essential function in rejecting pathogens and preventing mechanical, chemical, and physical damages. Keratinocytes are the predominant cells of the outer skin layer, the epidermis, which acts as a mechanical and water-permeability barrier. The epidermis is a permanently renewed tissue where undifferentiated keratinocytes located at the basal layer proliferate and migrate to the overlying layers. 
  • 2.1K
  • 27 May 2022
Topic Review
Google Book Search Settlement Agreement
The Google Book Search Settlement Agreement was a proposal between the Authors Guild, the Association of American Publishers, and Google in the settlement of Authors Guild et al. v. Google, a class action lawsuit alleging copyright infringement on the part of Google. The settlement was initially proposed in 2008, but ultimately rejected by the court in 2011. In November 2013, the presiding U.S. Circuit Judge dismissed Authors Guild et al. v. Google. On April 18, 2016, the Supreme Court turned down an appeal.
  • 2.1K
  • 14 Nov 2022
Topic Review
Biopolymer-Based Composites from Agricultural Waste Biomass
Natural fibers are derived from a variety of flora and fauna sources and are utilized in the production of textiles and other commodities. These materials are recognized for their capacity to decompose naturally, their ability to endure over time, and their positive impact on the ecosystem. Fibers derived from agricultural waste biomass pertain to fibers procured from the residual components of crops, including but not limited to straw, stalks, leaves, and husks.
  • 2.1K
  • 14 Jun 2023
Topic Review
Tin-iodate rechargeable battery
The tin-iodate battery is a rechargeable battery for large scale energy storage.
  • 2.1K
  • 04 Jan 2022
Topic Review
CeO2-based transition metal catalysts
The rational design and fabrication of highly-active and cost-efficient catalytic materials constitutes the main research pillar in catalysis field. In this context, the fine-tuning of size and shape at nanometer scale can exert an intense impact not only on the inherent reactivity of catalyst’s counterparts but also on their interfacial interactions, opening up new horizons for the development of highly active and robust materials. The main implications of ceria nanoparticles’ shape engineering (rods, cubes, polyhedra) in catalysis are revealed, on the ground of some of the most pertinent heterogeneous reactions, such as CO2 hydrogenation, CO oxidation, and N2O decomposition. It is clearly revealed that shape functionalization can remarkably affect the intrinsic features and in turn the reactivity of ceria nanoparticles. More importantly, by combining ceria nanoparticles (CeO2 NPs) of specific architecture with various transition metals (e.g., Cu, Fe, Co, Ni) remarkably active multifunctional composites can be obtained due mainly to the synergistic metal-ceria interactions, providing the design principles of earth-abundant metal oxide catalysts for various real-life environmental and energy applications.
  • 2.1K
  • 22 Apr 2021
Topic Review
Thiol-and Disulfide-Based Stimulus-Responsive Soft Materials
Thiols (RSH) and disulfides (RSSR) are components of many proteins, biopolymers, and biomolecules.  Many can be interconverted by simple oxidation and reduction reactions that change drastically their properties and those of host molecules of which they are a part.
  • 2.1K
  • 11 Jun 2021
Topic Review
Chinese Herbal Medicines for Sepsis Treatment
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection; the pathophysiology of sepsis is complex. The incidence of sepsis is steadily increasing, with worldwide mortality ranging between 30% and 50%. Current treatment approaches mainly rely on the timely and appropriate administration of antimicrobials and supportive therapies, but the search for pharmacotherapies modulating the host response has been unsuccessful. Chinese herbal medicines, i.e., Chinese patent medicines, Chinese herbal prescriptions, and single Chinese herbs, play an important role in the treatment of sepsis through multicomponent, multipathway, and multitargeting abilities and have been officially recommended for the management of COVID-19.
  • 2.1K
  • 01 Nov 2021
Topic Review
Interventions for Treatment of Eco-Anxiety
As climate change worsens and public awareness of its grave impact increases, individuals are increasingly experiencing distressing mental health symptoms which are often grouped under the umbrella term of eco-anxiety. Interventions for the treatment of eco-anxiety are proposed.
  • 2.1K
  • 29 Sep 2021
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