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Topic Review
Elastic Modulus
Elastic modulus (E) is a key parameter in predicting the ability of a material to withstand pressure and plays a critical role in the design of rock engineering projects. E has broad applications in the stability of structures in mining, petroleum, geotechnical engineering, etc. E can be determined directly by conducting laboratory tests, which are time consuming, and require high-quality core samples and costly modern instruments. Thus, devising an indirect estimation method of E has promising prospects.
  • 2.1K
  • 25 Mar 2022
Topic Review
Chakma Alphabet
The Chakma alphabet (Ajhā pāṭh), also called Ojhapath, Ojhopath, Aaojhapath, is an abugida used for the Chakma language.
  • 2.1K
  • 30 Oct 2022
Topic Review
Collagen Derived from Fish Industry Waste
Fish collagen garnered significant academic and commercial featuring prospective applications in a variety of health-related industries, including food, medicine, pharmaceutics, and cosmetics. Due to its distinct advantages over mammalian-based collagen, including the reduced zoonosis transmission risk, the absence of cultural-religious limitations, the cost-effectiveness of manufacturing process, and its superior bioavailability, the use of collagen derived from fish wastes (i.e., skin, scales) quickly expanded. Moreover, by-products are low cost and the need to minimize fish industry waste’s environmental impact paved the way for the use of discards in the development of collagen-based products with remarkable added value.
  • 2.1K
  • 07 Feb 2023
Topic Review
Peripartum Cardiomyopathy
Peripartum cardiomyopathy (PPCM) is a condition in which heart failure and left ventricular systolic dysfunction occur in the last month of pregnancy or within months following delivery.
  • 2.1K
  • 26 Jan 2021
Topic Review
Thymoquinone and Cancer
Thymoquinone (TQ) is a bioactive molecule with anticancer as well as anti-inflammatory activities via the downregulation of several chemokines and cytokines. Administering it as a nanoformulation increases its therapeutic value.
  • 2.1K
  • 22 Sep 2021
Topic Review
Application Programming Interface
Template:Hatnote group An application programming interface (API) is a computing interface which defines interactions between multiple software intermediaries. It defines the kinds of calls or requests that can be made, how to make them, the data formats that should be used, the conventions to follow, etc. It can also provide extension mechanisms so that users can extend existing functionality in various ways and to varying degrees. An API can be entirely custom, specific to a component, or it can be designed based on an industry standard to ensure interoperability. Through information hiding, APIs enable modular programming, which allows users to use the interface independently of the implementation.
  • 2.1K
  • 18 Oct 2022
Topic Review
Tau Isoforms
Tau was first described as a natively unfolded microtubule-associated protein. In fact, its main function is to promote the assembly of microtubules and stabilize their structure. However, Tau proteins have a variety of other functions, which include maintaining the structural integrity of neurons, contributing to signal transmission between neurons, and axonal transport. Tau also plays a role in regulating myelination, iron homeostasis, and neurogenesis and may also support synaptic plasticity. Other roles attributed to Tau are gene expression regulation, DNA protection, genome stability, microRNA activity, RNA protection, RNA metabolism, and protein synthesis.
  • 2.1K
  • 27 Dec 2022
Topic Review
Effects of Carpets on Indoor Air Quality
Interest in having a healthy and well-being environment has increased the awareness to improve indoor air quality (IAQ). Building materials influence the contribution of indoor air pollution, so understanding their behaviour on IAQ is essential. Among building materials, carpets cover surfaces of indoor environments and significantly impact IAQ due to their large surface area and multi-layers of materials components.
  • 2.1K
  • 10 Jan 2023
Topic Review
Molecular Mechanism of Alzheimer’s Disease
Alzheimer’s disease (AD) is the most prominent neurodegenerative disorder in the aging population. It is characterized by cognitive decline, gradual neurodegeneration, and the development of amyloid-β (Aβ)-plaques and neurofibrillary tangles, which constitute hyperphosphorylated tau. The early stages of neurodegeneration in AD include the loss of neurons, followed by synaptic impairment. Since the discovery of AD, substantial factual research has surfaced that outlines the disease’s causes, molecular mechanisms, and prospective therapeutics, but a successful cure for the disease has not yet been discovered. This may be attributed to the complicated pathogenesis of AD, the absence of a well-defined molecular mechanism, and the constrained diagnostic resources and treatment options. 
  • 2.1K
  • 25 May 2023
Topic Review
Vat Photopolymerization
Vat photopolymerization (VP), including stereolithography (SLA), digital light processing (DLP), and volumetric printing, employs UV or visible light to solidify cell-laden photoactive bioresin contained within a vat in a point-by-point, layer-by-layer, or volumetric manner.
  • 2.1K
  • 11 Oct 2023
Topic Review
Thermally Conductive Adhesive in Electronic Packaging
The application of epoxy adhesive is widespread in electronic packaging. Epoxy adhesives can be integrated with various types of nanoparticles for enhancing thermal conductivity. The joints with thermally conductive adhesive (TCA) are preferred for research and advances in thermal management. The rapid advancement of microelectronic technology has resulted in the progressive transformation of electronic components from isolated to highly integrated. It produces a lot of heat while they are functioning. The materials and structures used to attach the semiconductor chip to other electronic components involve the sector of electronic packaging. Conductive adhesives represent a significant advancement in electronic packaging for advanced devices, where effective heat dissipation and enough electrical conductivity are critical. The TCA joint is a crucial choice for the thermal management of the device. The advances in TCA are essential because of future demands for inexpensive and handy electronic devices. The adhesive applications have become more important due to their remarkable versatility and unparalleled compatibility. The electronic industry has indeed developed, especially in consumer electronics, which depends on conductive adhesives. It would not be possible to identify the most modern electronic devices without conductive adhesives.
  • 2.1K
  • 11 Oct 2021
Topic Review
The Hydrogen Color Spectrum
Hydrogen production involves different resources and energy loads, depending on the production method used. Therefore, the industry has tried to set a classification code for this energy carrier. This is done by using colors that reflect the hydrogen production method, the resources consumed to produce the required energy, and the number of emissions generated during the process.
  • 2.1K
  • 07 Feb 2023
Topic Review
Drosophila melanogaster Olfactory System
Drosophila melanogaster has provided a new dimension to the discipline of neuroscience. The research on olfactory and gustatory systems using fruit flies has grown rapidly during the last few years due to the strong genetic similarity that humans share with them.
  • 2.1K
  • 23 Feb 2022
Topic Review
Von Willebrand Factor
The von Willebrand factor (vWF) is a plasma protein that mediates platelet adhesion and leukocyte recruitment to vascular injury sites and carries coagulation factor VIII, a building block of the intrinsic pathway of coagulation. A steep rise in shear rates, which may occur at sites of arterial stenosis and injury, is crucial for unfolding and activation of vWF. The hemostatic activity of vWF is counterbalanced by ADAMTS-13, a vWF-cleaving protease. The presence of ultra-large multimers of vWF in the bloodstream is associated with spontaneous thrombosis, whereas its deficiency leads to bleeding.
  • 2.1K
  • 12 Nov 2020
Topic Review
Sperm Sex-Sorting
The utilization of sex-sorted sperm for artificial insemination and in-vitro fertilization is considered a valuable tool for improving production efficiency and optimizing reproductive management in farm animals, subsequently ensuring sufficient food resource for the growing human population. 
  • 2.1K
  • 29 Apr 2021
Topic Review
Alcohol Consumption and Male Fertility
Heavy alcohol consumption (defined as more than 3 and 4 drinks in a day, or more than 7 and 14 drinks weekly, for women and men, respectively) is reported to negatively affect human health, promote traffic accidents, and alter social behaviors, with severe repercussions for personal, social, and professional lives. Clinically, alcohol consumption has been correlated with an increased incidence of different types of cancer , cardiovascular  and liver diseases, birth defects, and psychiatric disorders.
  • 2.1K
  • 06 Jan 2022
Topic Review
HP OmniGo 700LX Communicator Plus
The HP 200LX Palmtop PC (F1060A, F1061A, F1216A), also known as project Felix, is a personal digital assistant introduced by Hewlett-Packard in August 1994. It was often called a Palmtop PC, and it was notable that it was, with some minor exceptions, a MS-DOS-compatible computer in a palmtop format, complete with a monochrome graphic display, QWERTY keyboard, serial port, and PCMCIA expansion slot.
  • 2.1K
  • 27 Oct 2022
Topic Review
Informational Social Influence
Social proof is a psychological and social phenomenon wherein people copy the actions of others in an attempt to undertake behavior in a given situation. The term was coined by Robert Cialdini in his 1984 book Influence: Science and Practice, and the concept is also known as informational social influence. Social proof is considered prominent in ambiguous social situations where people are unable to determine the appropriate mode of behavior, and is driven by the assumption that the surrounding people possess more knowledge about the current situation. The effects of social influence can be seen in the tendency of large groups to conform. This is referred to in some publications as the herd behavior. Although social proof reflects a rational motive to take into account the information possessed by others, formal analysis shows that it can cause people to converge too quickly upon a single distinct choice, so that decisions of even larger groups of individuals may be grounded in very little information (see information cascades). Social proof is one type of conformity. When a person is in a situation where they are unsure of the correct way to behave, they will often look to others for clues concerning the correct behavior. When "we conform because we believe that others' interpretation of an ambiguous situation is more accurate than ours and will help us choose an appropriate course of action", it is informational social influence. This is contrasted with normative social influence wherein a person conforms to be liked or accepted by others. Social proof often leads not only to public compliance (conforming to the behavior of others publicly without necessarily believing it is correct) but also private acceptance (conforming out of a genuine belief that others are correct). Social proof is more powerful when being accurate is more important and when others are perceived as especially knowledgeable. In 2020, a young scientist from Poland , Michal Klichowski, proved that this phenomenon also applies to interactions with artificial intelligence. His results show a new AI proof mechanism: AI that people have more and more contact with is becoming a new source of information about how to behave and what decisions to take.
  • 2.1K
  • 28 Nov 2022
Topic Review
Prunus
Prunus species, as climacteric fruits, have a short ripening period and shelf-life after harvest, with a fast period of softening.
  • 2.1K
  • 19 Jan 2021
Topic Review
Antisense Oligonucleotide-Based Therapy of Viral Infections
Antisense oligonucleotide (ASO) technology exploits a single-strand short oligonucleotide to either cause target RNA degradation or sterically block the binding of cellular factors or machineries to the target RNA. Chemical modification or bioconjugation of ASOs can enhance both its pharmacokinetic and pharmacodynamic performance, and it enables customization for a specific clinical purpose. ASO-based therapies have been used for treatment of genetic disorders, cancer and viral infections. In particular, ASOs can be rapidly developed for newly emerging virus and their reemerging variants. 
  • 2.1K
  • 29 Mar 2022
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