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Topic Review
21st Century Skills and Mobile-Technology-Supported Inquiry-Based Learning
The development of 21st-century skills is paramount. Among these skills, which encompass collaboration, communication, critical thinking, and creativity, Mobile-Technology-Supported Inquiry-Based Learning (mIBL) in Science Education emerges as a potent method for their enhancement.
  • 2.3K
  • 14 Nov 2023
Topic Review
Adaptor CAR Platforms
The success of conventional chimeric antigen receptor (CAR) therapy in the treatment of refractory hematologic malignancies has triggered the development of novel exciting experimental CAR technologies. Among them, adaptor CAR platforms have received much attention. They combine the flexibility and controllability of recombinant antibodies with the power of CARs. Due to their modular design, adaptor CAR systems propose answers to the central problems of conventional CAR therapy, such as safety and antigen escape.
  • 2.3K
  • 10 Oct 2020
Topic Review
Unsupervised Keyphrase Extraction
A review of unsupervised keyphrase extraction methods.
  • 2.3K
  • 21 Feb 2021
Topic Review
Grape Infusions
Grape-infusion preparation is no more than a sustainable or green way of extracting polyphenols and other nutraceutical compounds from grapes and grape leaves.  Grapes and grape/wine by-products are a rich source of health-promoting compounds, presenting great potential for the development of new beverages. 
  • 2.3K
  • 11 Aug 2021
Topic Review
Wearable Actuators
Applications of wearable actuators mainly include wearable robotics, haptic devices, and smart textiles. Wearable robotics have been proven valuable in rehabilitation, body assistance, and/or virtual reality. These applications cover systems of various sizes, from millimeter-scale biorobots to large deployable structures.
  • 2.3K
  • 03 Sep 2021
Topic Review
Youth's Vision:Significance of China's Development to the World
As young people in Africa, we hope to make use of China's development experience and achievements, strive to develop Africa, catch up with the pace of world development, and promote China-Africa friendship.
  • 2.3K
  • 28 Jan 2022
Topic Review
Tea and Its Active Constituents in Cosmetics
Tea plant itself and its extracts together with their centuries-old tradition of use play an important role on the cosmetics market. In general, cosmetics products containing tea extracts rich in polyphenols have a positive effect on the skin appearance and ameliorate skin damage, erythema and lipid peroxidation following UV exposure.
  • 2.3K
  • 29 Mar 2022
Topic Review
A Rule-Based Grapheme-to-Phoneme Conversion System
Natural language processing often requires grapheme-to-phoneme (G2P) conversion of an orthographic text. G2P converts strings of graphemes to corresponding sequences of phonetic transcription characters, directly from orthographic representations and it is crucial for many applications in various areas of speech and language processing.
  • 2.3K
  • 25 Mar 2022
Topic Review
Photocathode Materials
Photoelectrochemical water splitting is a promising approach to sustainable hydrogen production with no carbon emissions. Hydrogen being a future fuel to coming human generations is of utmost importance. The photocathodes in a photoelectrochemical (PEC) water-splitting cell are essential for the direct evolution of hydrogen. Among the known photocathodes, Cu-based p-type semiconducting materials are the most promising photo-absorber materials owing to their low-cost, low toxicity, natural abundance, suitable band-gaps, and favorable band edges for reduction. 
  • 2.3K
  • 08 Nov 2022
Topic Review
Bengal Fox
The Bengal Fox (Vulpes bengalensis) emerges as a fascinating and resilient member of the carnivore collection, thriving across the Indian subcontinent. This small canid, known for its distinctive appearance and adaptability, navigates diverse landscapes from grasslands to urban environments.
  • 2.3K
  • 28 Feb 2024
Topic Review
The Ponto-Geniculo-Occipital Waves in Dreaming
Rapid eye movement (REM) sleep is the main sleep correlate of dreaming. Ponto-geniculo-occipital (PGO) waves are a signature of REM sleep. They represent the physiological mechanism of REM sleep that specifically limits the processing of external information. PGO waves look just like a message sent from the pons to the lateral geniculate nucleus of the visual thalamus, the occipital cortex, and other areas of the brain. The dedicated visual pathway of PGO waves can be interpreted by the brain as visual information, leading to the visual hallucinosis of dreams. PGO waves are considered to be both a reflection of REM sleep brain activity and causal to dreams due to their stimulation of the cortex. 
  • 2.3K
  • 06 Nov 2023
Topic Review
Obfuscation
In software development, obfuscation is the act of creating source or machine code that is difficult for humans to understand. Like obfuscation in natural language, it may use needlessly roundabout expressions to compose statements. Programmers may deliberately obfuscate code to conceal its purpose (security through obscurity) or its logic or implicit values embedded in it, primarily, in order to prevent tampering, deter reverse engineering, or even to create a puzzle or recreational challenge for someone reading the source code. This can be done manually or by using an automated tool, the latter being the preferred technique in industry.
  • 2.3K
  • 11 Oct 2022
Topic Review
Convective Boundary Layer
The Convective Boundary layer (CBL), also known as the daytime Planetary boundary layer, is the part of the atmosphere most directly affected by solar heating of the earth's surface. This layer extends from the earth surface to a capping inversion that typically locates at a height of 1–2 km by midafternoon over land. Below the capping inversion (10-60% of CBL depth, also called entrainment zone in the daytime), CBL is divided into two sub-layers: mixed layer (35-80% of CBL depth) and surface layer (5-10% of CBL depth). The mixed layer, the major part of CBL, has a nearly constant distribution of quantities such as potential temperature, wind speed, moisture and pollutant concentration because of strong buoyancy generated convective turbulent mixing. Parameterization of turbulent transport is used to simulate the vertical profiles and temporal variation of quantities of interest, because of the randomness and the unknown physics of turbulence. However, turbulence in the mixed layer is not completely random, but is often organized into identifiable structures such as thermals and plumes in the CBL. Simulation of these large eddies is quite different from simulation of smaller eddies generated by local shears in the surface layer. Non-local property of the large eddies should be accounted for in the parameterization.
  • 2.3K
  • 24 Nov 2022
Topic Review
Ketoacid Analogues Supplementation in CKD
Diet is a key component of care during chronic kidney disease (CKD). In order to reduce the risk of nutritional disorders in very-low protein diets (VLDP), supplementation by nitrogen-free ketoacid analogues (KAs) have been proposed.
  • 2.3K
  • 06 Sep 2021
Topic Review
Seaweeds as a Fermentation Substrate
The interest in marine macroalgae are increasing  as novel and functional food and feed products. Marine macroalgae show a high flexibility and applicability due to the bioactive properties of the compounds produced. In the nutraceutical sector, the development of novel food products with high nutritious value and sustainable development raises the interest in this biological group.  Indeed, seaweeds mainly need exposure to sun, aeration, artificial or naturally, and seawater rich in nutrients to grow and obtain a high amount of biomass to then develop novel functional food products that can be produced by the fermentation method, mainly performed by lactic acid bacteria. Still, this is a topic that needs to be further developed in order to improve the beneficial and organoleptic  properties of seaweeds.Here is proposed to the potential of prebiotic and probiotic fermentation and the potential of seaweed in food and feed industrial sectors.
  • 2.3K
  • 08 Nov 2021
Topic Review
The Medicinal Properties for FDA-Approved Oximes
Organophosphate (OP) poisoning continues to be a major threat to humans. Oximes represent the most important class in medicinal chemistry, renowned for their widespread applications as OP antidotes, drugs and intermediates for the synthesis of several pharmacological derivatives. Common oxime based reactivators or nerve antidotes include pralidoxime, obidoxime, HI-6, trimedoxime and methoxime, among which pralidoxime is the only FDA-approved drug. Cephalosporins are β-lactam based antibiotics and serve as widely acclaimed tools in fighting bacterial infections. Oxime based cephalosporins have emerged as an important class of drugs with improved efficacy and a broad spectrum of anti-microbial activity against Gram-positive and Gram-negative pathogens.
  • 2.3K
  • 21 Jan 2022
Topic Review
Application of Quantum Mechanics/Molecular Mechanics Methodologies to Metalloproteins
The multiscaling quantum mechanics/molecular mechanics (QM/MM) approach was introduced in 1976, while the extensive acceptance of this methodology started in the 1990s. The combination of QM/MM approach with molecular dynamics (MD) simulation, otherwise known as the QM/MM/MD approach, is a powerful and promising tool for the investigation of chemical reactions’ mechanism of complex molecular systems, drug delivery, properties of molecular devices, organic electronics, etc. Applications of the QM/MM methodologies on metalloproteins are presented.  
  • 2.3K
  • 05 May 2022
Topic Review
Linguistics in Science Fiction
Linguistics has an intrinsic connection to Science Fiction stories given the nature of science fiction. As mentioned in Aliens and Linguists: Language Study and Science Fiction by Walter E. Meyers, science fiction is almost always concerned with the idea of communication, such as communication with aliens and machines, or communication using dead languages and evolved languages of the future. Authors of science fiction at times use Linguistics and Linguistic theories as a tool for storytelling, although technical terms are rarely used with authors only going into as much detail as the reader will understand. While Linguistics can be found to be employed by writers of science fiction, it must be noted that not all uses are accurate to actual Linguistics and Linguistic Theories. Nevertheless, there still exists the lingering presence and use of Linguistics (even if inaccurate) in such cases. As mentioned by Walter E. Meyers, the ability to make a story seem more unfamiliar and exotic, and an alien seem less of a costumed human who merely differs in physical appearance, is only possible through the use of language. It is this ability that appears to draw the boundary between great works of science fiction and those lesser so. As such, Linguistics, the scientific study of language, comes to hold an important role in the genre of science fiction.
  • 2.3K
  • 10 Nov 2022
Topic Review
Adherence
In medicine, patient compliance (also adherence, capacitance) describes the degree to which a patient correctly follows medical advice. Most commonly, it refers to medication or drug compliance, but it can also apply to other situations such as medical device use, self care, self-directed exercises, or therapy sessions. Both patient and health-care provider affect compliance, and a positive physician-patient relationship is the most important factor in improving compliance. Access to care plays a role in patient adherence, whereby greater wait times to access care contributing to greater absenteeism. The cost of prescription medication also plays a major role. Compliance can be confused with concordance, which is the process by which a patient and clinician make decisions together about treatment. Worldwide, non-compliance is a major obstacle to the effective delivery of health care. 2003 estimates from the World Health Organization indicated that only about 50% of patients with chronic diseases living in developed countries follow treatment recommendations with particularly low rates of adherence to therapies for asthma, diabetes, and hypertension. Major barriers to compliance are thought to include the complexity of modern medication regimens, poor "health literacy" and not understanding treatment benefits, occurrence of undiscussed side effects, poor treatment satisfaction, cost of prescription medicine, and poor communication or lack of trust between a patient and his or her health-care provider. Efforts to improve compliance have been aimed at simplifying medication packaging, providing effective medication reminders, improving patient education, and limiting the number of medications prescribed simultaneously. Studies show a great variation in terms of characteristics and effects of interventions to improve medicine adherence. It is still unclear how adherence can consistently be improved in order to promote clinically important effects.
  • 2.3K
  • 07 Nov 2022
Biography
Edward Wilson
Edward Adrian Wilson FZS (23 July 1872 – 29 March 1912) was an English polar explorer, ornithologist, natural historian, physician and artist. Born in Cheltenham on 23 July 1872, Wilson was the second son and fifth child of physician Edward Thomas Wilson and his wife, Mary Agnes, née Whishaw.[1] A clever, sensitive, but boisterous boy, he developed a love of the countryside, natural histo
  • 2.3K
  • 09 Dec 2022
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