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Topic Review
Maple Syrup Urine Disease
       Maple Syrup Urine Disease (MSUD) is caused by a deficiency of branched-chain α-ketoacid dehydrogenase (BCKD). It is a metabolic disorder characterized by increased levels of branched-chain amino acids (BCAAs) and their respective branched-chain α-ketoacids (BCKAs) [1]. 
  • 2.3K
  • 26 Oct 2020
Topic Review
Magnesium Oxide in Constipation
Magnesium oxide has been widely used as an osmotic laxative for a long time especially in East Asia. 
  • 2.3K
  • 04 Mar 2021
Topic Review
Olive Oil Using Gas Chromatography
Olive oil is among the most popular supplements of the Mediterranean diet due to its high nutritional value. Therefore, the authenticity of extra virgin olive oil (EVOO) and virgin olive oil (VOO) is of major importance for both financial and health-related reasons. However, at the same time, because of economical purposes, it is also one of the products most subjected to adulteration. As a result, authenticity is an important issue of concern among authorities and consumers. Especially, regarding consumers, they require high-quality food products which a real characterized botanical and geographical origin. To this end many analytical techniques able to identify geographical and botanical origin and consequently, guarantee its quality and authenticity, have been developed.
  • 2.3K
  • 26 Jul 2021
Topic Review
Goat Breeding for Xerophytic Thickets Management in Madagascar
Spiny thickets or xerophytic thickets (XTs) are a type of shrubby vegetation found in the far south and southwest of Madagascar, the driest parts of the island. This type of vegetation, which is rich in endemic animal and plant species, is endangered. Extensive local goat breeding (Capra hircus, for meat and milk production) based on XT browsing is an important source of household income. Improved goat breeding is an alternative to wood charcoal (WC) production and slash-and-burn agriculture (SBA), which are unsustainable activities.
  • 2.3K
  • 16 Mar 2022
Topic Review
Mechanisms of Hericium erinaceus in Alzheimer’s Disease
Alzheimer’s disease (AD) is a neurodegenerative disorder, and no effective treatments are available to treat this disorder. Hericium erinaceus (HE), also known as the monkey’s head mushroom, lion’s mane mushroom, or Yamabushitake, is commonly found in East Asia. It is well-known for its diverse therapeutic activities, including neuroprotection and neuroregeneration, which are attributed to its neurogenesis, antioxidative, and anti-neuroinflammatory functions. Therefore, researchers have been investigating HE as a possible treatment for AD.
  • 2.3K
  • 25 Aug 2022
Topic Review
Biodegradation of Plastics  by Fungal and Bacterial Communities
Biodegradation is the deformation of a substance into new compounds through biochemical reactions or the actions of microorganisms such as bacteria or fungi. It is necessary for water-soluble or water-immiscible polymers because they eventually enter streams which can neither be recycled nor incinerated. It is important to consider the microbial degradation of natural and synthetic polymers in order to understand what is necessary for biodegradation and the mechanisms involved. Low/high-density polyethylene is a vital cause of environmental pollution. It occurs by choking the sewer line through mishandling, thus posing an everlasting ecological threat. Environmental pollution due to the unscrupulous consumption of synthetic polymers derived from petroleum has an adverse impact on the environment since the majority of plastics do not degrade, and the further incineration of synthetic plastics generates CO2 and dioxin. This requires understanding the interactions between materials and microorganisms and the biochemical changes involved. Widespread studies on the biodegradation of plastics have been carried out in order to overcome the environmental problems associated with synthetic plastic waste. Awareness of the waste problem and its impact on the environment has awakened new interest in the area of degradable polymers through microbes viz., bacteria, fungi, and actinomycetes. The microbial degradation of plastics is caused by certain enzymatic activities that lead to a chain cleavage of polymers into oligomers and monomers.
  • 2.3K
  • 21 Oct 2022
Topic Review
Epulis
Epulis (Greek: ἐπουλίς; plural epulides) is any tumor like enlargement (i.e. lump) situated on the gingival or alveolar mucosa. The word literally means "(growth) on the gingiva", and describes only the location of the mass and has no further implications on the nature of the lesion. There are three types: fibromatous, ossifying and acanthomatous. The related term parulis (commonly called a gumboil) refers to a mass of inflamed granulation tissue at the opening of a draining sinus on the alveolus over (or near to) the root of an infected tooth. Another closely related term is gingival enlargement, which tends to be used where the enlargement is more generalized over the whole gingiva rather than a localized mass.
  • 2.3K
  • 30 Nov 2022
Topic Review
Molecular Hydrogen into the Body
It is known that molecular hydrogen is a relatively stable, ubiquitous gas that is a minor component of the atmosphere. At the same time, molecular hydrogen has been shown to have diverse biological effects. By the end of 2022, more than 2000 articles have been published in the field of hydrogen medicine, many of which are original studies.
  • 2.3K
  • 10 Mar 2023
Topic Review
Food Image Dataset and Segmentation Model
The development of vision-based dietary assessment (VBDA) systems. These systems generally consist of three main stages: food image analysis, portion estimation, and nutrient derivation. The effectiveness of the initial step is highly dependent on the use of accurate segmentation and image recognition models and the availability of high-quality training datasets. Food image segmentation still faces various challenges, and most existing research focuses mainly on Asian and Western food images. 
  • 2.3K
  • 09 Jan 2024
Topic Review
DPSIR Assessment on Ecosystem Services
The DPSIR framework (Driver – Pressure – State – Impact – Response) is a useful tool to assess and investigate the cause-effect within an ecosystem to aid better systems - thinking approach for stakeholders, policymakers and governance managers to draft response measures. The DPSIR framework helps to identify and analyse the different effects of human activities over the ecosystem services and human well-being in the different ecosystems such as estuarine, delta, river, coastal, etc. The varied human activities involves mining, construction, fishing, infrastructure development, etc. The DPSIR study shows a holistic view on several interlinked pressures and state changes in the ecosystems, also supporting the development of some potential responses to form systematic, sustainable approaches for mitigating and adapting the impacts caused by human activities. This contribution describes the application of DPSIR framework to study the impacts of sand mining and sand consumption in the Vietnam's Mekong Delta ecosystem services, 
  • 2.3K
  • 25 Nov 2020
Topic Review
Transferrin Receptors
 Transferrin is an iron-binding protein. It can be used as a ligand to deliver various proteins, genes, ions, and drugs to the target site via transferrin receptors for therapeutic or diagnostic purposes via transferrin receptors. 
  • 2.3K
  • 30 Nov 2022
Topic Review
Temperament
In psychology, temperament broadly refers to consistent individual differences in behavior that are biologically based and are relatively independent of learning, system of values and attitudes. Some researchers point to association of temperament with formal dynamical features of behavior, such as energetic aspects, plasticity, sensitivity to specific reinforcers and emotionality. Temperament traits (such as Neuroticism, Sociability, Impulsivity, etc.) remain its distinct patterns in behavior throughout adulthood but they are most noticeable and most studied in children. Babies are typically described by temperament, but longitudinal research in the 1920s began to establish temperament as something which is stable across the lifespan. Although a broad definition of temperament is agreed upon, many classification schemes for temperament have been developed, and there is no consensus. Historically, the concept of temperament (originally "temperamentums" in Latin means "mixtures") was a part of the theory of the four humors, with their corresponding four temperaments. This historical concept was explored by philosophers, psychologists, psychiatrists and psycho-physiologists from very early times of psychological science, with theories proposed by Immanuel Kant, Hermann Lotze, Ivan Pavlov, Carl Jung, Gerardus Heymans among others. More recently, scientists seeking evidence of a biological basis of personality have further examined the relationship between temperament and neurotransmitter systems and character (defined in this context as developmental aspects of personality). However, biological correlations have proven hard to confirm.
  • 2.3K
  • 06 Dec 2022
Topic Review
Canadian Arctic Archipelago
The Canadian Arctic Archipelago, also known as the Arctic Archipelago, is a group of islands north of the Canada mainland. Situated in the northern extremity of North America and covering about 1,424,500 km2 (550,000 sq mi), this group of 36,563 islands in the Arctic Sea comprises much of the territory of Northern Canada – most of Nunavut and part of the Northwest Territories. The Canadian Arctic Archipelago is showing some effects of global warming, with some computer estimates determining that melting there will contribute 3.5 cm (1.4 in) to the rise in sea levels by 2100.
  • 2.3K
  • 15 Nov 2022
Topic Review
Microglia and Astrocytes Dysfunction in Parkinson’s Disease
Parkinson’s disease (PD) is the second most common neurodegenerative disease, with symptoms such as tremor, bradykinesia with rigidity, and depression appearing in the late stage of life. The key hallmark of PD is the loss or death of dopaminergic neurons in the region substantia nigra pars compacta. Neuroinflammation plays a key role in the etiology of PD, and the contribution of immunity-related events spurred the researchers to identify anti-inflammatory agents for the treatment of PD. Microglia and astrocyte dysregulation has been reported in PD. Patients with PD develop neural toxicity, inflammation, and inclusion bodies due to activated microglia and a-synuclein–induced astrocyte conversion into A1 astrocytes. 
  • 2.3K
  • 13 Apr 2023
Topic Review
GTL in Wastewater Treatment
Gas-to-liquid (GTL) technology involves the conversion of natural gas into several liquid hydrocarbon products. The Fischer–Tropsch (F–T) process is the most widely applied approach for GTL, and it is the main source of wastewater in the GTL process. The wastewater is generally characterized by high chemical oxygen demand (COD) and total organic carbon (TOC) content due to the presence of alcohol, ketones and organic acids. The discharge of this highly contaminated wastewater without prior treatment can cause adverse effects on human life and aquatic systems. Here, we provide an overview of recent literature related to the application of biotechnology for the treatment of GTL process water.  It examines aerobic and anaerobic biological treatment methods that have been shown to reduce the concentration of COD and organic compounds in wastewater. Advanced biological treatment methods, such as cell immobilization and application of nanotechnology are also evaluated. The removal of alcohol and volatile fatty acids (VFA) from GTL wastewater can be achieved successfully under anaerobic conditions. However, the combination of anaerobic systems with aerobic biodegradation processes or chemical treatment processes can be a viable technology for the treatment of highly contaminated GTL wastewater with high COD concentration. The ultimate goal is to have treated wastewater that has good enough quality to be reused in the GTL process, which could lead to cost reduction and environmental benefits.
  • 2.3K
  • 28 Oct 2020
Topic Review
Rapid Nontranscriptional Effects of Calcifediol and Calcitriol
Classically, a secosteroid hormone, vitamin D, has been implicated in calcium and phosphate homeostasis and has been associated with the pathogenesis of rickets and osteomalacia in patients with severe nutritional vitamin D deficiency. The spectrum of known vitamin D-mediated effects has been expanded in recent years. However, the mechanisms of how exactly this hormone elicits its biological function are still not fully understood. The interaction of this metabolite with the vitamin D receptor (VDR) and, subsequently, with the vitamin D-responsive element in the region of specific target genes leading to the transcription of genes whose protein products are involved in the traditional function of calcitriol (known as genomic actions). Moreover, in addition to these transcription-dependent mechanisms, it has been recognized that the biologically active form of vitamin D3, as well as its immediate precursor metabolite, calcifediol, initiate rapid, non-genomic actions through the membrane receptors that are bound as described for other steroid hormones. So far, among the best candidates responsible for mediating rapid membrane response to vitamin D metabolites are membrane-associated VDR (VDRm) and protein disulfide isomerase family A member 3 (Pdia3). 
  • 2.3K
  • 29 Jun 2022
Topic Review
Traditional Ecological Knowledge versus Ecological Wisdom
A novel concept has emerged in the landscape planning and design field as a response to environmental sustainability, which is known as ecological wisdom (EW). EW is defined as the ability to make prudent actions in contextual ecological practices. On the other hand, Traditional ecological knowledge (TEK) has been developing for a long time and become a reference for environmental management. It refers to the evolving knowledge acquired by indigenous and local peoples over hundreds or thousands of years through direct contact with the environment. It is concerned with the relationship of living beings (including humans) with their traditional groups and environment. This study would like to search for evidence and define the distinction between both topics and find that they are distinct from their definition, agent, sources, and research scope. This study also found that TEK and EW could be similar when discussing the topic of indigenous culture capital, traditional knowledge, ecosystem services, and sustainability in the context of cultural landscape research. It also proposed a conceptual framework to help scholars to understanding the relationship between TEK and EW in the cultural landscape. Furthermore, states the potential areas for research improvement among TEK, EW, and its convergence.
  • 2.3K
  • 24 Aug 2022
Topic Review
Methylmercury in Aquatic Environments
Methylmercury (MeHg) is the most important and the most abundant organic Hg pollutant in the aquatic ecosystem that can affect human health through biomagnification. It is the most toxic organic Hg form, which occurs naturally and by human-induced contamination in water and is further biomagnified in the aquatic food web. MeHg is the only Hg form that accumulates in living organisms and is able to cross the blood–brain barrier, presenting an enormous health risk. Anthropogenic activity increases eutrophication of coastal waters worldwide, which promotes algae blooms. Microalgae, as primary producers, are especially sensitive to MeHg exposure in water and are an important entrance point for MeHg into the aquatic food web. MeHg assimilated by microalgae is further transferred to fish, wildlife and, eventually, humans as final consumers. MeHg biomagnifies and bioaccumulates in living organisms and has serious negative health effects on humans, especially newborns and children.
  • 2.3K
  • 07 Feb 2023
Topic Review
Extended Surfactants Using HLDN approach
Extended surfactants are molecules including an intramolecular extension that allow attaining high performance without the need for cosurfactant or linker alcohol. The polypropylene oxide chain intramolecular extension generates a polarity transition inside the molecule that produces more interactions with the oil and aqueous phases. The idea was developed in the 1990s, basically to fasten together the rather hydrophilic surfactant and the lipophilic linker, producing the same effect as the mixture without losing a part of the lipophilic linker going away from the interface. Since the lipophilic linker was an amphiphile with a small hydrophilic part located close to the interface, the single structure was developed to imitate the mixture situation. It contains a polar head located in water, then an intermediate slightly polar zone in the oil phase close to the interface, and finally, the surfactant classical hydrocarbon tail.
  • 2.3K
  • 14 Feb 2023
Topic Review
5G Flying Ad Hoc Networks
Flying ad hoc network (FANET) is an application of 5G access network, which consists of unmanned aerial vehicles or flying nodes with scarce resources and high mobility rates. It is one of the new applications supported by 5G. 5G incorporates new technologies, including massive multiple-input and multiple-output (MIMO), device-to-device (D2D) communication, coordinated multi-point (CoMP), and beamforming, providing new features, such as exploring and exploiting mmWave and underutilized spectrum. 
  • 2.3K
  • 15 Apr 2022
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