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Topic Review
Print-Light-Synthesis of Electrodes
Print-Light-Synthesis combines ink-based digital printing of thin liquid metal precursor films with high intensity light irradiation for the synthesis of metal nanoparticles and metal films. The method is generally applied to produce two-dimensional patterns of metal nanoparticles by printing a thin liquid film containing one or more metal precursors onto a target substrate and immediately reducing the metal precursors to metal nanoparticles by light exposure of the as-deposited thin liquid film. The process must be adjusted in a way that (i) the precursor reduction is at least as fast as printing and (ii) the light intensity is sufficient for highly efficient photo-induced processes. Otherwise, incomplete metal precursor reduction will occur. The metal precursor inks do not contain any stabilizing agents that are generally added in alternative wet chemical methods for nanoparticle synthesis. Print-Light-Synthesis is designed in such a way that pure nanomaterials remain on the substrate, while all other ink components, such as the solvents and other dissolved species, generate gases or evaporate at moderate temperatures. The use of mask-less digital printing techniques provides a large flexibility in terms of pattern design, pattern modification, and process optimization. Inkjet printing provides a high control of the desired metal loading on the substrate, simply by adjusting the ink composition and printing parameters, such as number of droplets per substrate area. Films of separate nanoparticles, inter-connected nanoparticles and complex nanostructures can be prepared. Print-Light-Synthesis can be used to reduce or oxidise metal precursors, depending on the target oxidation state of the metal.
  • 625
  • 20 Jul 2023
Topic Review
Nanomaterials for the Treatment of Osteosarcoma
Osteosarcoma (OSA) is a type of bone cancer that begins in the cells that form bones. OSA is a rare mesenchymal bone neoplasm derived from mesenchymal stem cells. Genome disorganization, chromosomal modifications, deregulation of tumor suppressor genes, and DNA repair defects are the factors most responsible for OSA development. Advancements in nanotechnology have made it possible to deliver the drug to various diseases including OSA.
  • 622
  • 05 Jun 2023
Topic Review
Micro-Combinatorial Technique in Materials Science
The novel, single-sample concept combinatorial method, the so-called micro-combinatory technique, has been shown to be suitable for the high-throughput and complex characterization of multicomponent thin films over an entire composition range. In addition to the 3 mm diameter TEM grid used for microstructural analysis, by scaling up the substrate size to 10 × 25 mm, this novel approach has allowed for a comprehensive study of the properties of the materials as a function of their composition, which has been determined via transmission electron microscopy (TEM), scanning electron microscopy (SEM), Rutherford backscattering spectrometry (RBS), X-ray diffraction analysis (XRD), atomic force microscopy (AFM), spectroscopic ellipsometry, and nanoindentation studies.
  • 620
  • 18 Jul 2023
Topic Review
Biomimetic Nanocarrier-Based Photothermal Therapy for Cancer Treatment
Nanomedicine presents innovative solutions for cancer treatment, including photothermal therapy (PTT). PTT centers on the design of photoactivatable nanoparticles capable of absorbing non-toxic near-infrared light, generating heat within target cells to induce cell death. The successful transition from benchside to bedside application of PTT critically depends on the core properties of nanoparticles responsible for converting light into heat and the surface properties for precise cell-specific targeting. Precisely targeting the intended cells remains a primary challenge in PTT.
  • 616
  • 08 Nov 2023
Topic Review
Hybrid Nanosystems “Antibiotic—Metal Nanoparticles”
Metallic nanoparticles (NPs) are an effective solution to overcome bacterial resistance to antibiotics. However, some of these NPs are toxic, which severely limits their biomedical applications. The combined use of metal NPs with antibiotic drugs can improve their bactericidal effectiveness. In some cases the revealed bactericidal effect of hybrid drug forms will lead to a reduction in the required doses and a decrease in their toxicity to human cells. Moreover, the combination of metal NPs and antibiotic drugs will preserve the ability of the latter to destroy bacteria that have become resistant to them.
  • 613
  • 13 Mar 2023
Topic Review
Platinum-Based Nanoformulations for Glioblastoma Treatment
Therapies for treating Glioblastoma (GB), and brain tumours in general, are inefficient and represent numerous challenges. In addition to surgical resection, chemotherapy and radiotherapy are presently used as standards of care. However, treated patients still face a dismal prognosis with a median survival below 15–18 months. Temozolomide (TMZ) is the main chemotherapeutic agent administered; however, intrinsic or acquired resistance to TMZ contributes to the limited efficacy of this drug. To circumvent the current drawbacks in GB treatment, a large number of classical and non-classical platinum complexes have been prepared and tested for anticancer activity, especially platinum (IV)-based prodrugs. Platinum complexes, used as alkylating agents in the anticancer chemotherapy of some malignancies, are though often associated with severe systemic toxicity (i.e., neurotoxicity), especially after long-term treatments.
  • 613
  • 22 May 2023
Topic Review
Extensive Use of Graphene in Detection of Viruses
Graphene and its derivatives offer considerable merits in biosensing applications for pathogenic virus detection.
  • 594
  • 31 Mar 2023
Topic Review
Magnetic Sample Preparation Methods Prior to Liquid Chromatography
Magnetic nanomaterials and nanostructures compose an innovative subject in sample preparation. Most of them are designed according to the properties of the target analytes on each occasion. The unique characteristics of nanomaterials enhance the proficiency at extracting and enriching due to their selective adsorption ability as well as easy separation and surface modification. Their remarkable properties, such as superparamagnetism, biocompatibility and selectivity have established magnetic materials as very reliable options in sample preparation approaches.
  • 593
  • 12 Jul 2023
Topic Review
Plasmon-Assisted Molecular Catalysis
The utilization of plasmonic nanomaterials in catalytic technologies is an emerging research field with foreseeable applications in energy-catalytic technologies. On this front, the coupling of plasmonic nanomaterials with molecular catalysts is a newly approached, thus far unexploited field.
  • 593
  • 11 Jan 2024
Topic Review
Synthesis of PbO Nanostructures
Black-phosphorus-analog lead monoxide (PbO), as a new emerging 2D material, has rapidly gained popularity due to its unique optical and electronic properties. Both theoretical prediction and experimental confirmation have revealed that PbO exhibits excellent semiconductor properties, including a tunable bandgap, high carrier mobility, and excellent photoresponse performance, which is undoubtedly of great interest to explore its practical application in a variety of fields, especially in nanophotonics. 
  • 592
  • 14 Jul 2023
Topic Review
Dendrimers and Dendritic Materials against Infectious Diseases
The COVID-19 pandemic showed more deeply the need of our society to provide new therapeutic strategies to fight infectious diseases, not only against currently known illnesses, where common antibiotics and drugs appear to be not fully effective, but also against new infectious threats that may arise. 
  • 589
  • 08 Feb 2022
Topic Review
Nanoparticle-Mediated Nucleic Acid Delivery Systems for Immunotherapy
Successful clinical results of immunotherapeutic approaches for cancer treatment were led by antibodies targeting immune checkpoints, and many have advanced through clinical trials and obtained FDA approval. A major opportunity remains for the development of nucleic acid technology for cancer immunotherapy in the form of cancer vaccines, adoptive T-cell therapies, and gene regulation. However, these therapeutic approaches face many challenges related to their delivery to target cells, including their in vivo decay, the limited uptake by target cells, the requirements for nuclear penetration (in some cases), and the damage caused to healthy cells. These barriers can be avoided and resolved by utilizing advanced smart nanocarriers (e.g., lipids, polymers, spherical nucleic acids, metallic nanoparticles) that enable the efficient and selective delivery of nucleic acids to the target cells and/or tissues.
  • 582
  • 28 Jun 2023
Topic Review
Nonmetallic Electrocatalysts for Oxygen Reduction Reactions
As a key role in hindering the large-scale application of fuel cells, oxygen reduction reaction has always been a hot issue and nodus. Nonmetallic catalysts have a low cost, good stability and resistance in oxygen reduction reactions. 
  • 574
  • 21 Jul 2023
Topic Review
Dimension Engineering in Noble-Metal-Based Nanocatalysts
Catalysts play a pivotal role in modern industries, such as energy, pharmaceuticals, and petrochemicals, serving as cornerstone of high-tech production. Noble metals, such as gold, silver, and platinum group elements, possess the superb catalytic characteristics of high-temperature oxidation resistance, corrosion resistance, stable electrochemical performance, high catalytic activity, and so on. These characteristics offer excellent prospects for applications in catalysis.
  • 574
  • 29 Jan 2024
Topic Review
Biomedical Applications of the AuNP-Liposome Nanocomposites
AuNP-liposome nanocomposites have been evaluated for several biomedical applications including imaging, sensing, cancer therapy, and light-responsive drug delivery.
  • 564
  • 24 Jul 2023
Topic Review
3D Structured Capacitive Sensors
Rapid technological advancements have led to increased demands for sensors. Hence, high performance suitable for next-generation technology is required. As sensing technology has numerous applications, various materials and patterning methods are used for sensor fabrication. This affects the characteristics and performance of sensors, and research centered specifically on these patterns is necessary for high integration and high performance of these devices. 
  • 563
  • 09 Nov 2023
Topic Review
Microenvironmental Behaviour of Nanotheranostic Systems
The development of smart, efficient and multifunctional material systems for diseases treatment are imperative to meet current and future health challenges. Nanomaterials with theranostic properties have offered a cost effective and efficient solution for disease treatment, particularly, metal/oxide based nanotheranostic systems already offering therapeutic and imaging capabilities for cancer treatment. Nanoparticles can selectively generate/scavenge ROS through intrinsic or external stimuli to augment/diminish oxidative stress. An efficient treatment requires higher oxidative stress/toxicity in malignant disease, with a minimal level in surrounding normal cells. The size, shape and surface properties of nanoparticles are critical parameters for achieving a theranostic function in the microenvironment. The exhibition of therapeutics properties such as selective reactive oxygen species (ROS) scavenging, hyperthermia, antibacterial, antiviral, and imaging capabilities such as MRI, CT and fluorescence activity have been reported in a variety of developed nanosystems to combat cancer, neurodegenerative and emerging infectious diseases.
  • 563
  • 09 Aug 2022
Topic Review
Tailoring Ceria-Based Nanocatalysts in Steam Reforming Processes
Ceria-based nanostructures, employed as catalytic supports for noble and non-noble metals, are well-known for their remarkable activity in steam-reforming reactions, exceptional resistance to degradation, and thermal stability.
  • 552
  • 28 Aug 2023
Topic Review
Formation of miRNA Nanoprobes
microRNAs (miRNA) captured the interest as novel diagnostic and prognostic biomarkers, with their potential for early indication of numerous pathologies. Since miRNA is a short, non-coding RNA sequence, the sensitivity and selectivity of their detection remain a cornerstone of scientific research. As such, methods based on nanomaterials have emerged in hopes of developing fast and facile approaches. At the core of the detection method based on nanotechnology lie nanoprobes and other functionalized nanomaterials. Since miRNA sensing and detection are generally rooted in the capture of target miRNA with the complementary sequence of oligonucleotides, the sequence needs to be attached to the nanomaterial with a specific conjugation strategy.
  • 543
  • 17 Jan 2023
Topic Review
Photo-Controlled Self-Assembly of Nanoparticles
Photo-controlled self-assembly of nanoparticles (NPs) is an advanced and promising approach to address a series of material issues from the molecular level to the nano/micro scale, owing to the fact that light stimulus is typically precise and rapid, and can provide contactless spatial and temporal control. Photoexcitation-induced assembly of NPs is another promising physical strategy, and such a strategy aims to employ molecular conformational change in the excited state (rather than the chemical structure) to drive molecular motion and assembly.
  • 543
  • 26 Sep 2023
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