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Topic Review
Silica Hydride
The silica hydride surface is composed of silicon-hydrogen groups, which is much more stable, less reactive and delivers different chromatographic and chemical characteristics.
  • 1.9K
  • 27 Dec 2021
Topic Review
Red Mud Liquid Media Recycling
Bauxite residue, known as red mud, is a by-product of alumina production using the Bayer process. Currently, its total global storage amounts to over 4.6 billion tons, including about 600 million tons in Russia. The total global storage of red mud occupies large areas, leading to environmental damage and increasing environmental risks. Moreover, it contains a significant amount of sodium, which is easily soluble in subsoil water; therefore, a sustainable approach for comprehensive recycling of red mud is necessary. The bauxite residue contains valuable elements, such as aluminum, titanium, and scandium, which can be recovered using liquid media.
  • 1.9K
  • 22 Jun 2021
Topic Review
Metal-Organic Frameworks-Based Sensors for Food Safety
Metal-organic frameworks (MOFs) are a class of crystalline porous materials systems structured by using metals linked together by organic bridging ligands.
  • 1.8K
  • 09 Feb 2022
Topic Review
Electrospun Medicated Nanofibers for Wound Healing
The electrospun nanofiber membrane has a unique structure and biological function similar to the extracellular matrix (ECM), and is considered an advanced wound dressing. They have significant potential in encapsulating and delivering active substances that promote wound healing. 
  • 1.8K
  • 22 Oct 2021
Topic Review
Polyhydroxyalkanoates (PHAs)
Polyhydroxyalkanoates (PHAs) are promising biodegradable and biocompatible polymers that can be obtained through microbial fermentation of agro-industrial byproducts, e.g., milk and cheese whey by using both microbial consortia and pure bacterial cultures.
  • 1.8K
  • 02 Dec 2021
Topic Review
Near-Infrared Spectroscopy Coupled to Hyperspectral Imaging
Near-infrared (800–2500 nm; NIR) spectroscopy coupled to hyperspectral imaging (NIR-HSI) has greatly enhanced its capability and thus widened its application and use across various industries. This non-destructive technique that is sensitive to both physical and chemical attributes of virtually any material can be used for both qualitative and quantitative analyses.
  • 1.8K
  • 18 Mar 2022
Topic Review
Untargeted Human Milk Metabolomics
Human milk (HM) is considered the gold standard for infant nutrition. HM contains macro- and micronutrients, as well as a range of bioactive compounds (hormones, growth factors, cell debris, etc.). The analysis of the complex and dynamic composition of HM has been a permanent challenge for researchers. The use of novel, cutting-edge techniques involving different metabolomics platforms has permitted to expand knowledge on the variable composition of HM. Here, the state-of-the-art in untargeted metabolomic studies of HM, with emphasis on sampling, extraction and analysis steps is presented.
  • 1.8K
  • 30 May 2022
Topic Review
Design of Calcium-Binding Proteins to Sense Calcium
Ca2+ is the most ubiquitous signaling molecule in the human body, regulating numerous biological functions including heartbeat, muscle contraction, neural function, cell development, and cell proliferation. Calcium dynamics result from fluxes in Ca2+ concentrations that vary in amplitude and duration, between intracellular compartments and between the intracellular and extracellular space and intracellular organelles. Calcium controls numerous biological processes by interacting with different classes of calcium binding proteins (CaBP’s), with different affinities, metal selectivities, kinetics, and calcium dependent conformational changes.
  • 1.8K
  • 18 Feb 2022
Topic Review
Advantages and Prospects for In Vitro PHA Synthesis
Polyhydroxyalkanoates (PHAs) are a series of structurally diverse storage polyesters that are accumulated by various bacterial species and stored intracellularly in the form of granules. They primarily act as carbon and energy storage compounds to sustain cell survival during starvation.
  • 1.8K
  • 30 May 2023
Topic Review
Anticancer effects of Coumarin Sulfonamides
Coumarin is an important six-membered aromatic heterocyclic pharmacophore, widely distributed in natural products and synthetic molecules. The versatile and unique features of coumarin nucleus, in combination with privileged sulfonamide moiety, have enhanced the broad spectrum of biological activities. The research and development of coumarin, sulfonamide-based pharmacology, and medicinal chemistry have become active topics, and attracted the attention of medicinal chemists, pharmacists, and synthetic chemists. Coumarin sulfonamide compounds and analogs as clinical drugs have been used to cure various diseases with high therapeutic potency, which have shown their enormous development value. The diversified and wide array of biological activities such as anticancer, antibacterial, anti-fungal, antioxidant and anti-viral, etc. were displayed by diversified coumarin sulfonamides.
  • 1.7K
  • 22 Mar 2022
Topic Review
Bioactive Edible Films/Coatings Based in Gums and Starch
Edible films and coatings allow preserving fresh and processed food, maintaining quality, preventing microbial contamination and/or oxidation reactions and increasing the shelf life of food products. The structural matrix of edible films and coatings is mainly constituted by proteins, lipids or polysaccharides. However, it is possible to increase the bioactive potential of these polymeric matrices by adding phenolic compounds obtained from plant extracts. Phenolic compounds are known to possess several biological properties such as antioxidant and antimicrobial properties. Incorporating phenolic compounds enriched plant extracts in edible films and coatings contribute to preventing food spoilage/deterioration and the extension of shelf life. 
  • 1.7K
  • 27 Jan 2022
Topic Review
Betulin
Betulin is an important triterpenoid substance isolated from birch bark, which, together with its sulfates, exhibits important bioactive properties. Using the potentiometric titration method, the product of acidity constants K1 and K2 of a solution of the betulin disulfate H+ form has been found to be 3.86 × 10–6 ± 0.004. It has been demonstrated by the thermal analysis that betulin and the betulin disulfate sodium salt are stable at temperatures of up to 240 and 220 °C, respectively. 
  • 1.7K
  • 28 Feb 2022
Topic Review
Nanostructured Lipid Carriers-Hydrogels System for Drug Delivery
Nanostructured lipid carriers (NLC) are lipid nanoparticles of the second generation made up of solid lipid matrices mixed with liquid lipids (oils). The hybrid system between NLC and hydrogel may results in the enhancement of each component's synergistic properties in the mechanical strength of the hydrogel and concomitantly decrease aggregation of the NLC. Therefore, the advanced hybrid component development in nanotechnology provides superior functionality in the application of scientific knowledge for the drug delivery industry. 
  • 1.7K
  • 25 Jan 2022
Topic Review
Stochastic Microsensors
Two three-dimensional (3D) stochastic microsensors based on immobilization of protoporphyrin IX (PIX) in single-walled carbon nanotubes (SWCNT) and multi-walled carbon nanotubes (MWCNT) decorated with copper (Cu) and gold (Au) nanoparticles were designed and used for the molecular recognition of isocitrate dehydrogenase 1 (IDH1) and isocitrate dehydrogenase 2 (IDH2) in biological samples (brain tumor tissues, whole blood).
  • 1.7K
  • 22 Feb 2022
Topic Review
Camelids' Milk
Camel milk has always represented an important food for nomadic people in the arid parts of the world; recently, camel milk attracted great attention as a possible replacer to dairy cow’s milk because of its therapeutic effects. The use of alternative milk for feeding children can be effective in reducing the development of gastrointestinal disorders.
  • 1.7K
  • 19 Apr 2022
Topic Review
Valence-shell Electron-pair Repulsion Model
There are the following main assumptions of the Valence-shell Electron-pair Repulsion (VSEPR) model. - The arrangement of covalent bonds of the atom centre analyzed depends on the number of electron pairs in its valence shell: bonds and nonbonding pairs as lone electron pairs. - The arrangement of valence electron pairs around the centre considered is to maximize their distances apart. - The non-valence electrons - inner electrons with nucleus (i.e. the core) possess the spherical symmetry (or at least it is in force for the main groups elements). It is worth to note that the intra- and intermolecular interactions influence on electronic and molecular structures in accordance with this VSEPR model.
  • 1.7K
  • 06 Sep 2021
Topic Review
Encapsulated Natural Bioactive Compounds in Food Industry
Plants are the most abundant bioresources, providing valuable materials that can be used as additives in polymeric materials, such as lignocellulosic fibers, nano-cellulose, or lignin, as well as plant extracts containing bioactive phenolic and flavonoid compounds used in the healthcare, pharmaceutical, cosmetic, and nutraceutical industries. Bioactive packaging is developing to additionally provides antibacterial and antioxidant activity with the same goals i.e., extending the shelf life while ensuring safety of the food products. New solutions are designed using natural antimicrobial and antioxidant agents such as essential oils, some polysaccharides, natural inorganic nanoparticles (nanoclays, oxides, metals as silver) incorporated/encapsulated into appropriate carriers in order to be used in food packaging. Electrospinning/electrospraying are receiving attention as encapsulation methods due to their cost-effectiveness, versatility and scalability. The electrospun nanofibers and electro–sprayed nanoparticles can preserve the functionality and protect the encapsulated bioactive compounds (BC).
  • 1.7K
  • 24 Dec 2021
Topic Review
Vancomycin with Muramyl Pentapeptide
Vancomycin and a native muramyl pentapeptide ended with D-alanine (MPP-D-Ala), and vancomycin and a modified muramyl pentapeptide ended with D-serine (MPP-D-Ser) form complexes in a very specific way. This complexes provide a basis for characterizing the type and stability of the connection. The type of experimentally measured and computer-simulated interactions opens the field for discussion on possible modifications to the structure of vancomycin or muramyl pentapeptide to obtain their desired characteristics.
  • 1.7K
  • 07 Feb 2022
Topic Review
Oxidative Quality of Dairy Powders
Lipid oxidation (LO) is a primary cause of quality deterioration in fat-containing dairy powders and is often used as an estimation of a products shelf-life and consumer acceptability. The LO process produces numerous volatile organic compounds (VOC) including aldehydes, ketones and alcohols, which are known to contribute to the development of off-flavours in dairy powders. The main factors influencing the oxidative state of dairy powders and the various analytical techniques used to detect VOC as indicators of LO in dairy powders are outlined.
  • 1.7K
  • 19 Oct 2021
Topic Review
DMAHDM Nanocomposite
Researchers have developed novel nanocomposites that incorporate additional biomaterials with dimethylaminohexadecyl methacrylate (DMAHDM) in order to reduce secondary caries. The aim of this review was to summarize the current literature and assess the synergistic antibacterial and remineralizing effects that may contribute to the prevention of secondary caries. An electronic search was undertaken in MEDLINE using PubMed, Embase, Scopus, Web of Science and Cochrane databases. 
  • 1.7K
  • 01 Jun 2021
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