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Topic Review
Optimates
The optimates (/ˈɒptɪməts/; Latin for "best ones", singular: optimas), also known as boni ("good men"), are a label in studies of the late Roman republic. They are seen as supporters of the continued authority of the senate. The importance of the term comes from Cicero's Pro Sestio, a speech published in 56 BC, in which he constructs two types of politicians.
  • 2.8K
  • 15 Nov 2022
Topic Review
Applications of Liquid Biopsy in Colorectal Cancer Screening
Colorectal cancer (CRC) represents the third most prevalent cancer worldwide and a leading cause of mortality among the population of western countries. However, CRC is frequently a preventable malignancy due to various screening tests being available. While failing to obtain real-time data, current screening methods (either endoscopic or stool-based tests) also require disagreeable preparation protocols and tissue sampling through invasive procedures, rendering adherence to CRC screening programs suboptimal. In this context, the necessity for novel, less invasive biomarkers able to identify and assess cancer at an early stage is evident. Liquid biopsy comes as a promising minimally invasive diagnostic tool, able to provide comprehensive information on tumor heterogeneity and dynamics during carcinogenesis.
  • 2.8K
  • 17 Nov 2022
Topic Review
Cracks Types and Causes of Laser Cladding Coatings
Laser cladding, a novel surface treatment technology, utilizes a high-energy laser beam to melt diverse alloy compositions and form a specialized alloy-cladding layer on the surface of the substrate to enhance its property. However, it can generate substantial residual stresses during the rapid cooling and heating stages, due to inadequate selection of cladding process parameters and disparities in thermophysical properties between the clad layer and substrate material, leading to the formation of various types of cracks. These cracks can significantly impact the quality and performance of the coating.
  • 2.8K
  • 26 Jun 2023
Topic Review
Cholera Pit
A cholera pit was a burial place used in a time of emergency when the disease was prevalent. Such mass graves were often unmarked and were placed in remote or specially selected locations. Public fears of contagion, lack of space within existing churchyards and restrictions placed on the movements of people from location to location also contributed to their establishment and use. Many of the victims were poor and lacked the funds for memorial stones, however memorials were sometimes added at a later date.
  • 2.8K
  • 04 Nov 2022
Topic Review
Shellac and Its Potential in the Packaging Application
Shellac, an insect-derived material, has received the least attention due to its scarcity in south Asia. Currently, Shellac is used in various applications, such as furniture polish, glazing agent for candies and pharmaceutical pills, coating on fruits to increase shelf life, primers, smart sensor, 3D printing, and green electronic. However, the limitations of Shellac such as: brittleness with time, self-esterification, low transparency, solubility in alkaline medium and in most organic solvents have limited its usage in the packaging application. Many of these problems can be improved by physical blending or chemical reaction with other materials to make Shellac more durable, impede self-esterification, and facilitate the film-forming ability, which suggests the potential usage of Shellac in packaging applications.
  • 2.8K
  • 21 Apr 2023
Topic Review
Acer Predator
Predator Gaming is a gamer-focused brand and line of computer hardware owned by Acer. In 2008, Acer introduced itself in the gaming computer market with a line of desktop computers: the Acer Aspire Predator series, later renamed as Acer Predator. The series is characterized by the futuristic computer chassis and high performance. In 2016, a complete range of Predator desktops, gaming laptops, tablets and accessories exists. The range competes with Lenovo's Legion, Dell's G series and Alienware subsidiary, HP's Omen and Asus ROG series.
  • 2.8K
  • 20 Oct 2022
Topic Review
Eye Involvement in Wilson’s Disease
Wilson’s disease (WD) is an autosomal recessive genetic disorder due to a mutation of the ATP7B gene, resulting in impaired hepatic copper excretion and accumulation in various tissues. Ocular findings are one of the hallmarks of the disease. Many ophthalmological manifestations have been described and new techniques are currently available to improve their diagnosis and to follow their evolution. The most common ocular findings seen in WD patients are Kayser–Fleischer ring (KFR) and sunflower cataracts. Other ocular manifestations may involve retinal tissue, visual systems and eye mobility. Diagnosis and follow-up under decoppering treatment of these ocular findings are generally easily performed with slit-lamp examination (SLE). However, new techniques are available for the precocious detection of ocular findings due to WD and may be of great value for non-experimented ophthalmologists and non-ophthalmologists practitioners. 
  • 2.8K
  • 18 Aug 2022
Topic Review
Mid-infrared Ultrashort Pulse
Mid-infrared (MIR) ultrashort laser pulses, with wavebands ranging from 2 to 20 µm, have a wide range of applications in the fields of environmental monitoring, laser medicine, food quality control, strong-field physics, attosecond science, and some other aspects. There are various technologies for MIR ultrashort pulse generation towards different wavebands.
  • 2.8K
  • 01 Jun 2022
Topic Review
Human Detection in Heavy Smoke Scenarios
The most dangerous factor in a fire scene is smoke and heat, especially smoke. How to locate people and guide them out of a heavy smoke environment will be the key to surviving an evacuation process. A variety of instruments have been studied that can be used in fire and smoky situations, including visible camera, kinetic depth sensor, LIDAR, night vision, IR camera, radar, and sonar.
  • 2.8K
  • 04 Aug 2022
Topic Review
Biomass Pyrolysis Processes for Bioenergy Production
Bioenergy has emerged to be among the primary choices for the short- and medium-term replacement of fossil fuels and the reduction in greenhouse gas (GHG) emissions. The most practical method for transforming biomass into biofuel is thermochemical conversion, which may be broken down into combustion, torrefaction, pyrolysis, hydrothermal liquefaction, and gasification.
  • 2.8K
  • 08 Aug 2023
Topic Review
Iridoschisis
Iridoschisis is a rare condition defined as a separation of the anterior iris stroma from the posterior stroma and muscle layers. A variety of ocular pathologies can coexist with iridoschisis, but in most cases the causal relationship, if any, is unclear. Glaucoma, primarily angle-closure glaucoma, is the most often described condition concomitant to iridoschisis. Other ocular abnormalities found relatively often in iridoschisis patients include cataract, lens subluxation and corneal abnormalities. Iridoschisis is plausibly a multifactorial disease. A patient diagnosed with iridoschisis should be screened for potential glaucoma, corneal and lens abnormalities. Iridoschisis may pose a challenge for both an ophthalmologist in an outpatient setting and an ophthalmic surgeon.
  • 2.8K
  • 10 Nov 2020
Topic Review
Metallurgical Coke Structures
The structure of coke affects its reactivity and strength, which directly influences its performance in the blast furnace.
  • 2.8K
  • 11 Feb 2022
Topic Review
Foursquare
Foursquare is a local search-and-discovery service mobile app which provides search results for its users. The app provides personalized recommendations of places to go to near a user's current location based on users' "previous browsing history, purchases, or check-in history". The service was created in late 2008 and launched in 2009 by Dennis Crowley and Naveen Selvadurai. Crowley had previously founded the similar project Dodgeball as his graduate thesis project in the Interactive Telecommunications Program (ITP) at New York University. Google bought Dodgeball in 2005 and shut it down in 2009, replacing it with Google Latitude. Dodgeball user interactions were based on SMS technology, rather than an application. Foursquare was the second iteration of that same idea, that people can use mobile devices to interact with their environment. Foursquare was Dodgeball reimagined to take advantage of the new smartphones, like the iPhone, which had built in GPS to better detect a user's location. Until late July 2014, Foursquare featured a social networking layer that enabled a user to share their location with friends, via the "check in" - a user would manually tell the application when they were at a particular location using a mobile website, text messaging, or a device-specific application by selecting from a list of venues the application locates nearby. In May 2014, the company launched Swarm, a companion app to Foursquare, that reimagined the social networking and location sharing aspects of the service as a separate application. On August 7, 2014 the company launched Foursquare 8.0, the completely new version of the service which finally removed the check in and location sharing entirely, to focus entirely on local search. As of December 2013, Foursquare reported 45 million registered users, though many of these will not be active users. Male and female users are equally represented and also 50 percent of users are outside the US. Support for French, Italian, German, Spanish, and Japanese was added in February 2011. Support for Indonesian, Korean, Portuguese, Russian, and Thai was added in September 2011. Support for Turkish was added in June 2012. On January 14, 2016, Co-founder Dennis Crowley stepped down from his position as CEO. He moved to an Executive Chairman position while Jeff Glueck, the company's COO, succeeded Crowley as the new CEO.
  • 2.8K
  • 28 Nov 2022
Topic Review
Saudi Gig Economy
Gig labor in Saudi Arabia is consistent with the nation’s Vision 2030 objectives. This strategic vision prioritizes equal opportunities for everyone, revamps the education system to match market needs, and acknowledges the pivotal role of small- and medium-sized enterprises (SMEs) in driving economic growth.
  • 2.8K
  • 22 Dec 2023
Topic Review
Dye Adsorption of Biochar
Biochar (BC) is a highly stable carbonaceous material that is aromatized and amorphous in nature. It is usually formed after thermochemical conversion of organic matter and wastes at temperatures of 350–750 °C under limited oxygen conditions. It is being studied to a great degree because of its potential for carbon sequestration, soil improvement, climate change mitigation, catalysis, wastewater treatment, energy storage, and waste management.
  • 2.8K
  • 12 Aug 2022
Topic Review
Sjögren’s Syndrome Pathogenic Molecular Pathways
Sjögren’s syndrome (SS) is a systemic autoimmune rheumatic disorder characterized by the lymphocytic infiltration of exocrine glands and the production of autoantibodies to self-antigens. The involvement of the exocrine glands drives the pathognomonic manifestations of dry eyes (keratoconjunctivitis sicca) and dry mouth (xerostomia) that define sicca syndrome.
  • 2.8K
  • 01 Nov 2022
Topic Review
Bahá'í Faith and Science
A fundamental principle of the Bahá'í Faith is the stated harmony of religion and science. Whilst Bahá'í scripture asserts that true science and true religion can never be in conflict, critics argue that statements by the founders clearly contradict current scientific understanding. `Abdu'l-Bahá, the son of the founder of the religion, stated that "when a religion is opposed to science it becomes mere superstition". He also said that true religion must conform to the conclusions of science. This latter aspect of the principle seems to suggest that the religion must always accept current scientific knowledge as authoritative, but some Bahá'í scholars have suggested that this is not always the case. On some issues, the Bahá'í Faith subordinates the conclusions of current scientific thought to its own teachings, which the religion takes as fundamentally true. This is because, in the Bahá'í understanding the present scientific view is not always correct, neither is truth said to be only limited to what science can explain. Instead, in the Bahá'í view, knowledge must be obtained through the interaction of the insights obtained from revelation from God and through scientific investigation.
  • 2.8K
  • 08 Nov 2022
Topic Review
Requirements Engineering in OTF-Computing
The idea of On-The-Fly (OTF) Computing is to compose and provide software services ad hoc, based on requirement descriptions in natural language. Since non-technical users write  their software requirements themselves and in unrestricted natural language, deficits occur such as inaccuracy and incompleteness. These deficits are usually tackled by natural language processing methods, which have to face specific challenges in OTF Computing because maximum automation is the goal there. In the following, we present current automatic approaches for solving inaccuracies and incompleteness in natural language requirement descriptions.
  • 2.8K
  • 30 Oct 2020
Topic Review
Hormones for Oral Bone and Periodontal Tissue Engineering
Hormones are unique regulatory chemicals that govern fertility, growth, maturation, and microenvironmental maintenance, in addition to power generation, usage, and storage. Hormones play a fundamental function in the maintenance of the integrity of both periodontium and bone. Bone tissue is made up of many cell types and an extracellular matrix that is mostly made up of collagen proteins. Bone’s primary roles are structural support, mechanical motions, blood cell formation, and tissue preservation; it also serves as a depot of calcium and phosphate ions in the body.
  • 2.8K
  • 26 Jul 2022
Topic Review
Machine-Vision-Based Leather Surface Defect Inspection
Machine-vision-based surface defect inspection is one of the key technologies to realize intelligent manufacturing. Leather products are regarded as the most traded products all over the world. Automatic detection, location, and recognition of leather surface defects are very important for the intelligent manufacturing of leather products, and are challenging but noteworthy tasks. Machine-learning-based defect inspection methods include three main links in industrial applications: data annotation, model training, and model inference. Real-time performance in real industrial applications focuses more on this part of model inference.
  • 2.8K
  • 12 Aug 2022
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