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Topic Review
Coyote Reconnaissance Vehicle
The Light Armoured Vehicle II (LAV II) Coyote (and the related Bison) are armoured cars (or armoured personnel carriers) built by General Dynamics Land Systems Canada for the Canadian Forces. They are a later generation of the LAV-25 and of the same family as the Australian ASLAV, as all are part of the Light Armoured Vehicle family produced by General Dynamics Land Systems - Canada and based on the MOWAG Piranha 8x8.
  • 2.8K
  • 03 Nov 2022
Topic Review
Role of  Insects in Spread of  Foodborne Pathogens
Insects play a key role in European agroecosystems. Insects provide important ecosystem services and make a significant contribution to the food chain, sustainable agriculture, the farm-to-fork (F2F) strategy, and the European Green Deal. Edible insects are regarded as a sustainable alternative to livestock. 
  • 2.8K
  • 20 Feb 2023
Topic Review
Awns
Awns are extending structures from lemmas in grasses and are very active in photosynthesis, contributing directly to the filling of the developing grain. Barley (Hordeum vulgare L.) awns are highly diverse in shape and length and are known to be controlled by multiple awn-related genes. The genetic effects of these genes on awn diversity and development in barley are multiplexed and include complementary effect, cumulative effect, duplicate effect, recessive epistasis, dominant epistasis, and inhibiting effect, each giving a unique modified Mendelian ratio of segregation. The complexity of gene interactions contributes to the awn diversity in barley. Excessive gene interactions create a challenging task for genetic mapping and specific strategies have to be developed for mapping genes with specific interactive effects. Awn gene interactions can occur at different levels of gene expression, from the transcription factor-mediated gene transcription to the regulation of enzymes and metabolic pathways. A better understanding of gene interactions will greatly facilitate deciphering the genetic mechanisms underlying barley awn diversity and development. 
  • 2.8K
  • 07 May 2021
Topic Review
Queen Snake
The queen snake (Regina septemvittata) is a species of nonvenomous semiaquatic snake, a member of the subfamily Natricinae of the family Colubridae. The species is endemic to North America.
  • 2.8K
  • 24 Oct 2022
Topic Review
Adenoids and Tonsils: Immune System's Tireless Gatekeepers
Within the intricate realm of the mucosal immune system resides a captivating duo: the adenoids (or pharyngeal tonsils) and the tonsils (including palatine, tubal, and lingual variations), which harmoniously form the Waldeyer’s ring. As they are strategically positioned at the crossroads of the respiratory and gastrointestinal systems, these exceptional structures fulfill a vital purpose. They function as formidable “gatekeepers” by screening microorganisms—both bacteria and viruses—with the mission to vanquish local pathogens via antibody production. However, under specific circumstances, their function can take an unsettling turn, inadvertently transforming them into reservoirs for pathogen incubation.
  • 2.8K
  • 28 Jun 2023
Topic Review
CAR-T Cells in Pancreatic cancer
Pancreatic cancer has the worst prognosis and lowest survival rate among all types of cancers and thus, there exists a strong need for novel therapeutic strategies. Chimeric antigen receptor (CAR)-modified T cells present a new potential option after successful FDA-approval in hematologic malignancies, however, current CAR T cell clinical trials in pancreatic cancer failed to improve survival and were unable to demonstrate any significant response. The physical and environmental barriers created by the distinct tumor microenvironment (TME) as a result of the desmoplastic reaction in pancreatic cancer present major hurdles for CAR T cells as a viable therapeutic option in this tumor entity. Cancer cells and cancer-associated fibroblasts express extracellular matrix molecules, enzymes, and growth factors, which can attenuate CAR T cell infiltration and efficacy. Recent efforts demonstrate a niche shift where targeting the TME along CAR T cell therapy is believed or hoped to provide a substantial clinical added value to improve overall survival.
  • 2.8K
  • 16 Oct 2020
Topic Review
Woven Natural Fibre Polymer Composites
These woven materials are flexible, able to be tailored to the specific needs and have better mechanical properties due to their weaving structures.
  • 2.8K
  • 03 Mar 2021
Topic Review
Epigenetic Regulations of T Cell Differentiation
T cell differentiation is a tightly regulated process. Recent studies have shown that epigenetics plays a significant role at all stages of the differentiation process.  The different stages of T cell differentiation are introduced and recent findings on the epigenetic regulation of this process will be discussed. The epigenetic modifications associated with T cell differentiation related to cancer are discussed as well.
  • 2.8K
  • 18 Jul 2022
Topic Review
Understanding HII Framework and Related Technologies
The Unified Extensible Firmware Interface (UEFI) is currently the most popular industry standard, defining the software interface between an operating system and its underlying platform firmware. HII (Human Interface Infrastructure) is a part of the UEFI specification, which provides a standard framework for managing user interfaces based on UEFI systems. 
  • 2.8K
  • 17 Nov 2023
Topic Review
Cross-Cultural Psychology
Cross-cultural psychology is the scientific study of human behavior and mental processes, including both their variability and invariance, under diverse cultural conditions. Through expanding research methodologies to recognize cultural variance in behavior, language, and meaning it seeks to extend and develop psychology. Since psychology as an academic discipline was developed largely in North America and Europe, some psychologists became concerned that constructs accepted as universal were not as invariant as previously assumed, especially since many attempts to replicate notable experiments in other cultures had varying success. Since there are questions as to whether theories dealing with central themes, such as affect, cognition, conceptions of the self, and issues such as psychopathology, anxiety, and depression, may lack external validity when "exported" to other cultural contexts, cross-cultural psychology re-examines them using methodologies designed to factor in cultural differences so as to account for cultural variance. Some critics have pointed to methodological flaws in cross-cultural psychological research, and claim that serious shortcomings in the theoretical and methodological bases used impede, rather than help the scientific search for universal principles in psychology. Cross-cultural psychologists are turning more to the study of how differences (variance) occur, rather than searching for universals in the style of physics or chemistry. While cross-cultural psychology represented only a minor area of psychology prior to WWII, it began to grow in importance during the 1960s. In 1971, the interdisciplinary Society for Cross-Cultural Research (SCCR) was founded, and in 1972 the International Association for Cross-Cultural Psychology (IACCP) was established. Since then, this branch of psychology has continued to expand as there has been an increasing popularity of incorporating culture and diversity into studies of numerous psychological phenomena. Cross-cultural psychology is differentiated from cultural psychology, which refers to the branch of psychology that holds that human behavior is strongly influenced by cultural differences, meaning that psychological phenomena can only be compared with each other across cultures to a limited extent. In contrast, cross-cultural psychology includes a search for possible universals in behavior and mental processes. Cross-cultural psychology "can be thought of as a type [of] research methodology, rather than an entirely separate field within psychology". In addition, cross-cultural psychology can be distinguished from international psychology which centers around the global expansion of psychology especially during recent decades. Nevertheless, cross-cultural psychology, cultural psychology, and international psychology are united by a common concern for expanding psychology into a universal discipline capable of understanding psychological phenomena across cultures and in a global context.
  • 2.8K
  • 18 Oct 2022
Biography
Paul Winchell
Paul Winchell (né Wilchinsky; December 21, 1922 – June 24, 2005) was an American ventriloquist, comedian, actor, voice artist, humanitarian, and inventor whose career flourished in the 1950s and 1960s. From 1950 to 1954, he hosted The Paul Winchell Show, which also used two other titles during its prime time run on NBC: The Speidel Show, and What's My Name?. From 1965–1968, Winchell hosted
  • 2.8K
  • 23 Nov 2022
Topic Review
Ocean Wave Power Generation Systems
According to the theory of mechanical vibration, only when the wave power generation system resonates with the ocean wave can the energy of the ocean wave be converted into electric energy to the greatest extent. Several topics are discussed: the current situation of ocean wave power generation system tests in real ocean waves; the optimization design of linear generator for converting ocean wave energy into electrical energy; some optimization control methods to improve the operational efficiency of ocean wave power generation systems; and the current policy and financial support of ocean wave power generation in some countries. 
  • 2.8K
  • 04 Jan 2022
Topic Review
Vitamin A in Retinal Diseases
Vitamin A is an essential fat-soluble vitamin that occurs in various chemical forms. It is essential for several physiological processes. Either hyper- or hypovitaminosis can be harmful. One of the most important vitamin A functions is its involvement in visual phototransduction, where it serves as the crucial part of photopigment, the first molecule in the process of transforming photons of light into electrical signals. In this process, large quantities of vitamin A in the form of 11-cis-retinal are being isomerized to all-trans-retinal and then quickly recycled back to 11-cis-retinal. Complex machinery of transporters and enzymes is involved in this process (i.e., the visual cycle). Any fault in the machinery may not only reduce the efficiency of visual detection but also cause the accumulation of toxic chemicals in the retina. 
  • 2.8K
  • 10 Feb 2022
Topic Review
Frequency Multipliers for Terahertz Remote Sensing System
Terahertz (THz) electromagnetic waves have frequencies in the range of 0.1 THz to 10 THz, with corresponding wavelengths of 3 mm to 30 μm. This frequency range is adjacent to millimeter-wave electromagnetic frequencies and infrared light wavelengths, and is thereby associated with the engineering domain of both electromagnetics and photonics. Due to insufficient development and utilization, this frequency is often referred to as a “terahertz gap”. Terahertz-wave technologies have unique properties that include a large-magnitude skin depth, good directivity, wide bandwidth and high imaging resolution. Therefore, terahertz-wave technologies possess an unparalleled advantage for remote sensing applications.
  • 2.8K
  • 07 Jun 2022
Topic Review
Lysine Acetylation
Acetylation of lysine residues is a key post-translational modification for protein functions in all eukaryotic organisms. Acetylation of lysine residues can be catalyzed by lysine acetyltransferases (KATs) or modified by abundant Ac-CoA through nonenzymatic mechanisms. Conversely, lysine deacetylation is catalyzed by lysine deacetylases (KDACs).
  • 2.8K
  • 20 Oct 2020
Topic Review
Electric Vehicles
E-mobility sustainability assessment is becoming more comprehensive with research integrating social aspects without focusing only on technical, economic, and/or environmental perspectives. The transportation sector is indeed one of the leading and most challenging greenhouse-gas polluters, and e-mobility is seen as one of the potential solutions; however, a social perspective must be further investigated to improve the perception of and acceptance of electric vehicles. 
  • 2.8K
  • 04 Feb 2021
Topic Review
GM B Platform
The B platform (also known as the B body) is a full-size rear-wheel drive car platform produced by General Motors from 1926 to 1996. Originally made for Oldsmobile and Buick, all of General Motors's five main makes would use it at some point. It was closely related to the original rear-wheel drive GM C and GM D platforms, and was used for convertibles, hardtops, coupes, sedans, and station wagons. With approximately 12,960,000 units built, divided across four marques, the 1965-70 B platform is the fourth best selling automobile platform in history after the Volkswagen Beetle, Ford Model T and the Lada Riva. Originally, the B platform was used for Buick and Oldsmobile products, with the first GM A platform for Chevrolet and Oakland, and the above GM C and D platforms devoted to Cadillac. During the General Motors Companion Make Program, Vikings and Marquettes were also manufactured on this platform, as were La Salles from 1936 to 1940. The B platform was used for the Pontiac Streamliner Torpedo and Streamliner, the Oldsmobile L-Series, Series 70 and Series 88, the Buick Special and Century, the LaSalle Series 50 and the Cadillac Series 60, Series 61 and Series 63. The B platform became GM's base model platform in 1958, when all existing Chevrolet products were upgraded to the B platform. For the 1959 model year, the previous A and B bodies were built on the new B platform that lasted until 1996. During this period, the B was the most modest of GM's three full-sized platforms, slotting below the upscale C and the luxury D. The A platform designation would be resurrected by GM in 1964 for a new series of intermediate-sized cars including the Chevrolet Chevelle, Pontiac Tempest, Oldsmobile Cutlass and Buick Skylark.
  • 2.8K
  • 24 Nov 2022
Topic Review
Attribution Questionnaire
The Attribution Questionnaire (AQ) is a 27-item self-report assessment tool designed to measure public stigma towards people with mental illnesses. It assesses emotional reaction and discriminatory responses based on answers to a hypothetical vignette about a man with schizophrenia named Harry. There are several different versions of the vignette that test multiple forms of attribution. Responses assessing stigma towards Harry are in the form of 27 items rated on a Likert scale ranging from 1 (not at all) to 9 (very much). There are 9 subscales within the AQ that breakdown the responses one could have towards a person with mental illness into different categories. The AQ was created in 2003 by Dr. Patrick Corrigan and colleagues and has since been revised into smaller tests because of the complexity and hypothetical that did not capture children and adolescent's stigmas well. The later scales are the Attribution Questionnaire-9 (AQ-9), the revised Attribution Questionnaire (r-AQ), and the children's Attribution Questionnaire (AQ-8-C).
  • 2.8K
  • 30 Nov 2022
Topic Review
Colorectal Cancer Screening and Diagnostics
Colorectal cancer (CRC) is a prevalent and potentially fatal disease categorized based on its high incidences and mortality rates, which raised the need for effective diagnostic strategies for the early detection and management of CRC. While there are several conventional cancer diagnostics available, they have certain limitations that hinder their effectiveness. 
  • 2.8K
  • 17 Oct 2023
Topic Review
Methods for Reducing Water Absorption of Composite Materials
Plant fiber reinforced polymer matrix composites have attracted much attention in many industries due to their abundant resources, low cost, biodegradability, and lightweight properties. Compared with synthetic fibers, various plant fibers are easy to obtain and have different characteristics, making them a substitute for synthetic fiber composite materials. In order to address the adverse effects of natural fiber moisture absorption on the mechanical properties and dimensional stability of composite materials, researchers have modified fibers through various chemical and physical methods. The various methods to reduce the water absorption of composite materials such as fiber surface chemical treatment, the use of compatibilizers, fiber mixing, nanofillers, and polymer coatings.
  • 2.8K
  • 27 Oct 2023
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