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Topic Review
FileMaker Pro
FileMaker Pro is a cross-platform relational database application from Claris International, a subsidiary of Apple Inc. It integrates a database engine with a graphical user interface (GUI) and security features, allowing users to modify the database by dragging new elements into layouts, screens, or forms. FileMaker evolved from a DOS application, but was then developed primarily for the Apple Macintosh and released in April 1985. It was succeeded by FileMaker Pro in 1990. Since 1992 it has been available for Microsoft Windows and for the classic Mac OS and macOS, and can be used in a cross-platform environment. FileMaker server briefly ran on Linux, but Linux support was abandoned with FileMaker 7, thereafter only running on Windows or macOS servers. A client version was released for iOS devices in July 2010. It is available in desktop, server, iOS and web-delivery configurations. In 2016, FileMaker Cloud was introduced, including a Linux server (CentOS), which was offered exclusively through the Amazon Marketplace. In November 2019, FileMaker Cloud was reintroduced as a software as a service product offered directly from Claris for FileMaker Pro 18.0.3 using FileMaker Server Cloud 2.18 service on Amazon Servers, but managed by Claris instead of through the Amazon Market Place, and making use of the new FileMaker ID authentication.
  • 2.9K
  • 28 Oct 2022
Topic Review
Wittig Reactions under Sonication Conditions
Carbonyl olefinations are among the most important organic syntheses that form C=C bonds, as they usually have high yields and in addition offer excellent stereoselectivity. Due to these advantages, carbonyl olefinations have important pharmaceutical and industrial applications. These reactions contain an additional step of an α-functionalized carbanion to an aldehyde or ketone to produce alkenes, but syntheses performed using metal carbene complexes are also known. The Wittig reaction is an example of carbonyl olefination, one of the best ways to synthesize alkenes.
  • 2.9K
  • 28 Jun 2023
Topic Review
Protein Folding: Enigma and Solution
Protein folding is a process that converts the unfolded, disordered protein chain into a chain having a definite, unique three-dimensional structure.
  • 2.9K
  • 23 Apr 2021
Topic Review
Microbial Degradation of Rubber: Actinobacteria
Rubber is an essential part of our daily lives with thousands of rubber-based products being made and used. Natural rubber undergoes chemical processes and structural modifications, while synthetic rubber, mainly synthetized from petroleum by-products are difficult to degrade safely and sustainably. The most prominent group of biological rubber degraders are Actinobacteria. Rubber degrading Actinobacteria contain rubber degrading genes or rubber oxygenase known as latex clearing protein (lcp). Rubber is a polymer consisting of isoprene, each containing one double bond. The degradation of rubber first takes place when lcp enzyme cleaves the isoprene double bond, breaking them down into the sole carbon and energy source to be utilized by the bacteria. Actinobacteria grow in diverse environments, and lcp gene containing strains have been detected from various sources including soil, water, human, animal, and plant samples. 
  • 2.9K
  • 23 Jun 2021
Topic Review
Cell Sheet Harvesting Techniques
Cell sheet engineering is an advanced scaffold-free tissue engineering technique applicable to repairing or regenerating defective tissues and organs. It has proven to be an important breakthrough technology in regenerative medicine. 
  • 2.9K
  • 24 Feb 2023
Topic Review
Woolly Mammoth (Mammuthus primigenius)
The woolly mammoth (Mammuthus primigenius) was a large, elephant-like mammal that lived during the Ice Age. It belonged to the family Elephantidae, which includes modern elephants. It was characterized by its long, curved tusks, thick fur, and adaptations to extremely cold climates. The woolly mammoth was one of the last surviving members of the Mammuthus genus and played a significant role in Pleistocene ecosystems. Its extinction around 4,000 years ago was due to a combination of climate change and human activity.
  • 2.9K
  • 19 Mar 2025
Topic Review
GIS and IoT Integration
Internet-of-Things (IoT) concentrates on enabling communication between Things. It is a broadband network that uses standard communication protocols. Geospatial Information System (GIS) is a powerful set of tools that deal with capturing geospatial data, managing that data in a database, analyzing and pattern recognition, and finally visualizing information. IoT, as an emerging technology along with GIS, can result in advanced and user-friendly features in Smart Cities.
  • 2.9K
  • 17 Nov 2021
Topic Review
Biofuel
A biofuel is a fuel that is produced through contemporary processes from biomass, rather than a fuel produced by the very slow geological processes involved in the formation of fossil fuels, such as oil. Since biomass technically can be used as a fuel directly (e.g. wood logs), some people use the terms biomass and biofuel interchangeably. More often than not, however, the word biomass simply denotes the biological raw material the fuel is made of, or some form of thermally/chemically altered solid end product, like torrefied pellets or briquettes. The word biofuel is usually reserved for liquid or gaseous fuels, used for transportation. The U.S. Energy Information Administration (EIA) follows this naming practice. If the biomass used in the production of biofuel can regrow quickly, the fuel is generally considered to be a form of renewable energy. Biofuels can be produced from plants (i.e. energy crops), or from agricultural, commercial, domestic, and/or industrial wastes (if the waste has a biological origin). Renewable biofuels generally involve contemporary carbon fixation, such as those that occur in plants or microalgae through the process of photosynthesis. Some argue that biofuel can be carbon-neutral because all biomass crops sequester carbon to a certain extent – basically all crops move CO2 from above-ground circulation to below-ground storage in the roots and the surrounding soil. For instance, McCalmont et al. found below-ground carbon accumulation ranging from 0.42 to 3.8 tonnes per hectare per year for soils below Miscanthus x giganteus energy crops, with a mean accumulation rate of 1.84 tonne (0.74 tonnes per acre per year), or 20% of total harvested carbon per year. However, the simple proposal that biofuel is carbon-neutral almost by definition has been superseded by the more nuanced proposal that for a particular biofuel project to be carbon neutral, the total carbon sequestered by the energy crop's root system must compensate for all the above-ground emissions (related to this particular biofuel project). This includes any emissions caused by direct or indirect land use change. Many first generation biofuel projects are not carbon neutral given these demands. Some have even higher total GHG emissions than some fossil based alternatives. Some are carbon neutral or even negative, though, especially perennial crops. The amount of carbon sequestrated and the amount of GHG (greenhouse gases) emitted will determine if the total GHG life cycle cost of a biofuel project is positive, neutral or negative. A carbon negative life cycle is possible if the total below-ground carbon accumulation more than compensates for the total life-cycle GHG emissions above ground. In other words, to achieve carbon neutrality yields should be high and emissions should be low. High-yielding energy crops are thus prime candidates for carbon neutrality. The graphic on the right displays two CO2 negative Miscanthus x giganteus production pathways, represented in gram CO2-equivalents per megajoule. The yellow diamonds represent mean values. Further, successful sequestration is dependent on planting sites, as the best soils for sequestration are those that are currently low in carbon. The varied results displayed in the graph highlights this fact. For the UK, successful sequestration is expected for arable land over most of England and Wales, with unsuccessful sequestration expected in parts of Scotland, due to already carbon rich soils (existing woodland) plus lower yields. Soils already rich in carbon includes peatland and mature forest. Grassland can also be carbon rich, and Milner et al. argue that the most successful carbon sequestration in the UK takes place below improved grasslands. The bottom graphic displays the estimated yield necessary to compensate for related lifecycle GHG-emissions. The higher the yield, the more likely CO2 negativity becomes. The two most common types of biofuel are bioethanol and biodiesel. Bioethanol is an alcohol made by fermentation, mostly from carbohydrates produced in sugar or starch crops such as corn, sugarcane, or sweet sorghum. Cellulosic biomass, derived from non-food sources, such as trees and grasses, is also being developed as a feedstock for ethanol production. Ethanol can be used as a fuel for vehicles in its pure form (E100), but it is usually used as a gasoline additive to increase octane and improve vehicle emissions. Bioethanol is widely used in the United States and in Brazil. Biodiesel is produced from oils or fats using transesterification and is the most common biofuel in Europe. It can be used as a fuel for vehicles in its pure form (B100), but it is usually used as a diesel additive to reduce levels of particulates, carbon monoxide, and hydrocarbons from diesel-powered vehicles. In 2018, worldwide biofuel production reached 152 billion liters (40 billion gallons US), up 7% from 2017, and biofuels provided 3% of the world's fuels for road transport. The International Energy Agency want biofuels to meet more than a quarter of world demand for transportation fuels by 2050, in order to reduce dependency on petroleum. However, the production and consumption of biofuels are not on track to meet the IEA's sustainable development scenario. From 2020 to 2030 global biofuel output has to increase by 10% each year to reach IEA's goal. Only 3% growth annually is expected. Here are some various social, economic, environmental and technical issues relating to biofuels production and use, which have been debated in the popular media and scientific journals.
  • 2.9K
  • 12 Oct 2022
Topic Review
Sandilya Vidya
Śāṇḍilya Vidya is a set of teachings of vidyā or philosophy by the ancient Hindu sage Śāṇḍilya. It is part of the Agnirahasyama of the Shatapatha Upanishad, and its precepts are also set out in the Chandogya Upanishad. The work treats of the universal Absolute (Brahman) and of the practice of faith (Bhakti).
  • 2.9K
  • 17 Nov 2022
Topic Review
Principles of Prototropic Equilibria
Prototropic tautomers always differ by the positions of labile proton(s) and π-electrons. The number of possible tautomeric forms is an internal property of the tautomeric molecule. It is a consequence of the number of labile protons and the number of conjugated tautomeric sites.
  • 2.9K
  • 01 Nov 2023
Topic Review
Decentralized Community Composting
In recent years, there has been a huge interest from local communities in decentralized composting. Decentralized community composting refers to a community-scale network in a specific neighborhood that diverts and composts biowaste in a controlled operative environment. In fact, the lack of centralized composting facilities in small towns or rural areas can be supported by decentralized solutions. Decentralizing waste treatment facilities and thus creating local solutions to urban waste management strategies will help to achieve the resource recovery and valorization targets in line with the circular economy.
  • 2.9K
  • 29 Oct 2020
Topic Review
Wetland Systems
We provide here an overview of the use and role of aquatic macrophytes in constructed wetland systems. The ability of plants to remove metals, pharmaceutical products, pesticides, cyanotoxins and nanoparticles in constructed wetlands were compared with the removal effciency of non-planted systems, aiming to evaluate the capacity of plants to increase the removal effciency of the systems. Moreover, this review also focuses on the management and destination of the biomass produced through natural processes of water filtration. The use of macrophytes in constructed wetlands represents a promising technology, mainly due to their effciency of removal and the cost advantages of their implantation. However, the choice of plant species composing constructed wetlands should not be only based on the plant removal capacity since the introduction of invasive species can become an ecological problem.
  • 2.9K
  • 17 Nov 2020
Topic Review
Solar-Powered Plant Protection Equipment
Solar photovoltaic (PV) devices present a positive approach to sustainable crop production by reducing crop loss in various ways. This might result in the extensive use of PV devices in the near future. PV-based plant protection equipment/devices are primarily utilized in protecting crops from birds, weeds, or insects. The utilization of PV systems for different applications constitutes a new era in agriculture, horticulture, and forest sectors. A PV system is a potential alternative, offering more opportunities in operating different types of electricity-based agricultural equipment. The development of devices with simple construction/operation for plant protection may work well on small-scale farms.
  • 2.9K
  • 28 Nov 2022
Topic Review
NF-κB
The family of NF-κB is composed of five members of proteins linking to DNA, (RelA, RelB, RelC, NFκ-B1, and NFκ-B2) that trigger a set of inflammatory downstream effectors after nuclear translocation, involved in a broad range of biological processes. Either a canonical or a non-canonical pathway can be responsible for their activation; the canonical pathway mediates inflammatory responses and leads to a rapid but transient NF-κB activation, while the non-canonical signalling is a slow, long-lasting pathway.
  • 2.9K
  • 27 Oct 2020
Biography
Arthur Eddington
Sir Arthur Stanley Eddington OM FRS[1] (28 December 1882 – 22 November 1944) was an English astronomer, physicist, and mathematician. He was also a philosopher of science and a populariser of science. The Eddington limit, the natural limit to the luminosity of stars, or the radiation generated by accretion onto a compact object, is named in his honour. Around 1920, he anticipated the discover
  • 2.9K
  • 14 Nov 2022
Topic Review
Communication Costs in Federated Learning
Federated learning (FL) is an emerging distributed machine learning technique that allows for the distributed training of a single machine learning model across multiple geographically distributed clients.
  • 2.9K
  • 31 Aug 2023
Topic Review
Carbohydrate Maldigestion and Intolerance
When malabsorbed carbohydrates reach the colon, they are fermented by colonic bacteria, with the production of short-chain fatty acids and gas lowering colonic pH. The appearance of diarrhoea or symptoms of flatulence depends in part on the balance between the production and elimination of these fermentation products. Different studies have shown that there are no differences in the frequency of sugar malabsorption between patients with irritable bowel disease (IBS) and healthy controls; however, the severity of symptoms after a sugar challenge is higher in patients than in controls. 
  • 2.9K
  • 19 May 2022
Topic Review
Health Benefits of Chlorophylls and Chlorophyll-Rich Agro-Food
Chlorophylls play a crucial role in photosynthesis and are abundantly found in green fruits and vegetables that form an integral part of our diet. Although limited, existing studies suggest that these photosynthetic pigments and their derivatives possess therapeutic properties. These bioactive molecules exhibit a wide range of beneficial effects, including antioxidant, antimutagenic, antigenotoxic, anti-cancer, and anti-obesogenic activities.
  • 2.9K
  • 10 Aug 2023
Topic Review
Hypersexuality
Hypersexuality is extremely frequent or suddenly increased libido. It is currently controversial whether it should be included as a clinical diagnosis used by mental healthcare professionals. Nymphomania and satyriasis were terms previously used for the condition in women and men, respectively. Hypersexuality may be a primary condition, or the symptom of another medical disease or condition; for example, Klüver-Bucy syndrome or bipolar disorder. Hypersexuality may also present as a side effect of medication such as drugs used to treat Parkinson's disease. Clinicians have yet to reach a consensus over how best to describe hypersexuality as a primary condition, or to determine the appropriateness of describing such behaviors and impulses as a separate pathology. Hypersexual behaviours are viewed variously by clinicians and therapists as a type of obsessive-compulsive disorder (OCD) or "OCD-spectrum disorder", an addiction, or a disorder of impulsivity. A number of authors do not acknowledge such a pathology and instead assert that the condition merely reflects a cultural dislike of exceptional sexual behavior. Consistent with there not being any consensus over what causes hypersexuality, authors have used many different labels to refer to it, sometimes interchangeably, but often depending on which theory they favor or which specific behavior they were studying. Contemporary names include compulsive masturbation, compulsive sexual behavior, cybersex addiction, erotomania, "excessive sexual drive", hyperphilia, hypersexuality, hypersexual disorder, problematic hypersexuality, sexual addiction, sexual compulsivity, sexual dependency, sexual impulsivity, "out of control sexual behavior", and paraphilia-related disorder.
  • 2.9K
  • 31 Oct 2022
Topic Review
Non-Thermal Food Processing and Preservation
Non-thermal food processing refers to methods where the food materials receive microbiological inactivation without the direct application of heat. Such technologies, largely combined with hurdle technology to replace those conventional thermal food processing ones, are increasingly viewed as either emerging, novel, or new food processing methods. Such novel technologies have included pulsed electric fields (PEF), high-pressure processing (HPP), ozone treatment, pulsed light, non-thermal plasma/cold plasma (NTP), and ultrasound technology. The technologies can be grouped into two major groups: physical processes (pulse electric field, high-pressure processing, ultraviolet radiation, pulsed light, ultrasound, and ionizing radiation) and chemical processes (ozone treatment, and cold plasma).
  • 2.9K
  • 23 Jun 2021
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