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Topic Review
Asynchronous Environment Assessment
The emergence and global spread of COVID-19 has disrupted the traditional mechanisms of education throughout the world. Institutions of learning were caught unprepared and this jeopardised the face-to-face method of curriculum delivery and assessment. Teaching institutions have shifted to an asynchronous mode whilst attempting to preserve the principles of integrity, equity, inclusiveness, fairness, ethics, and safety. A framework of assessment that enables educators to utilise appropriate methods in measuring a student’s progress is crucial for the success of teaching and learning, especially in health education that demands high standards and comprises consistent scientific content. 
  • 3.1K
  • 30 Sep 2021
Topic Review
Digital Marketing
The concept of digital marketing is based on a combination of traditional marketing tools and online technologies enabled by the internet in the 1990s . Its synonyms include but are not limited to digital marketing, electronic marketing, e-marketing, and online marketing.
  • 3.1K
  • 22 Jul 2021
Topic Review Peer Reviewed
Fungi in a One Health Perspective
Fungi constitute a diverse group with highly positive and negative impacts in different environments, having several natural roles and beneficial applications in human life, but also causing several concerns. Fungi can affect human health directly, but also indirectly by being detrimental for animal and plant health, influencing food safety and security. Climate changes are also affecting fungal distribution, prevalence, and their impact on different settings. Searching for sustainable solutions to deal with these issues is challenging due to the complex interactions among fungi and agricultural and forestry plants, animal production, environment, and human and animal health. In this way, the “One Health” approach may be useful to obtain some answers since it recognizes that human health is closely connected to animal and plant health, as well as to the shared environment. This review aims to explore and correlate each of those factors influencing human health in this “One Health” perspective. Thus, the impact of fungi on plants, human, and animal health, and the role of the environment as an influencing factor on these elements are discussed.
  • 3.1K
  • 24 Jul 2023
Topic Review
Type I Collagen
Type I collagen, the predominant protein of vertebrates, assembles into fibrils that orchestrate the form and function of bone, tendon, skin, and other tissues. Collagen plays roles in hemostasis, wound healing, angiogenesis, and biomineralization, and its dysfunction contributes to fibrosis, atherosclerosis, cancer metastasis, and brittle bone disease.
  • 3.1K
  • 26 Jan 2021
Topic Review
Multiplex Immunohistochemistry/Immunofluorescence (mIHC/IF) Techniques
Multiplex imaging techniques and digital image analysis are powerful tools that could overcome some issues concerning tumour-microenvironment studies. This novel approach to biomarker assessment offers a better understanding of the complicated interactions between tumour cells and their environment. Multiplex labelling enables the detection of multiple markers simultaneously and the exploration of their spatial organisation. 
  • 3.1K
  • 02 Sep 2022
Topic Review
Asterism
An asterism is an observed pattern or group of stars in the sky. Asterisms can be any identified pattern or group of stars, and therefore are a more general concept than the formally defined 88 constellations. Constellations are based on asterisms, but unlike asterisms, constellations outline and today completely divide the sky and all its celestial objects into regions around their central asterisms. For example, the asterism known as the Big Dipper comprises the seven brightest stars in the constellation Ursa Major. Another is the asterism of the Southern Cross, within the constellation of Crux. Asterisms range from simple shapes of just a few stars to more complex collections of many stars covering large portions of the sky. The stars themselves may be bright naked-eye objects or fainter, even telescopic, but they are generally all of a similar brightness to each other. The larger brighter asterisms are useful for people who are familiarizing themselves with the night sky. The patterns of stars seen in asterisms are not necessarily a product of any physical association between the stars, but are rather the result of the particular perspectives of their observations. For example the Summer Triangle is a purely observational physically unrelated group of stars, but the stars of Orion's Belt are all members of the Orion OB1 association and five of the seven stars of the Big Dipper are members of the Ursa Major Moving Group. Physical associations, such as the Hyades or Pleiades, can be asterisms in their own right and part of other asterism at the same time.
  • 3.1K
  • 29 Nov 2022
Topic Review
TRNT1 and tRNA Maturation
tRNA nucleotidyl transferase 1 (TRNT1) is an essential enzyme catalyzing the addition of terminal cytosine-cytosine-adenosine (CCA) trinucleotides to all mature tRNAs, which is necessary for aminoacylation. It was recently discovered that partial loss-of-function mutations in TRNT1 are associated with various, seemingly unrelated human diseases including sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay (SIFD), retinitis pigmentosa with erythrocyte microcytosis, and progressive B-cell immunodeficiency. In addition, even within the same disease, the severity and range of the symptoms vary greatly, suggesting a broad, pleiotropic impact of imparting TRNT1 function on diverse cellular systems. This entry describes the current state of knowledge of the TRNT1 function and the phenotypes associated with mutations in TRNT1.
  • 3.1K
  • 05 Nov 2020
Topic Review
Biological Activities of Chlorogenic Acids
The chlorogenic acids (CGAs) are a class of phenolic compounds widely distributed in various plants sources such as fruits, vegetables, coffee beans, tea, apples, and wine. CGAs are esters of quinic acid (QA) and one trans-cinnamic acid residue such as caffeic acid (CA), p-coumaric acid (p-CoA), and ferulic acid (FA), which are known as caffeoylquinic acids (CQAs), p-coumaroylquinic acids (p-CoQAs) and feruloylquinic acid (FQAs).
  • 3.1K
  • 10 Jun 2022
Topic Review
Population and Housing Censuses by Country
This is a list of national population and housing censuses.
  • 3.1K
  • 20 Oct 2022
Topic Review
Sierpinski Number
In number theory, a Sierpiński number is an odd natural number k such that [math]\displaystyle{ k \times 2^n + 1 }[/math] is composite for all natural numbers n. In 1960, Wacław Sierpiński proved that there are infinitely many odd integers k which have this property. In other words, when k is a Sierpiński number, all members of the following set are composite: If the form is instead [math]\displaystyle{ k \times 2^n - 1 }[/math], then k is a Riesel number.
  • 3.1K
  • 02 Dec 2022
Topic Review
Connor-Davidson Resilience Scale
The Connor-Davidson Resilience Scale (CD-RISC) was developed by Kathryn M. Connor and Jonathan R.T. Davidson as a means of assessing resilience. The CD-RISC is based on Connor and Davidson's operational definition of resilience, which is the ability to "thrive in the face of adversity." Since its development in 2003, the CD-RISC has been tested in a several contexts with a variety of populations (see Generalizability) and has been modified into different versions (see Forms).
  • 3.1K
  • 21 Oct 2022
Topic Review
WebRTC
WebRTC (Web Real-Time Communication) is a free and open-source project providing web browsers and mobile applications with real-time communication (RTC) via application programming interfaces (APIs). It allows audio and video communication to work inside web pages by allowing direct peer-to-peer communication, eliminating the need to install plugins or download native apps. Supported by Apple, Google, Microsoft, Mozilla, and Opera, WebRTC specifications have been published by the World Wide Web Consortium (W3C) and the Internet Engineering Task Force (IETF). According to the webrtc.org website, the purpose of the project is to "enable rich, high-quality RTC applications to be developed for the browser, mobile platforms, and IoT devices, and allow them all to communicate via a common set of protocols".
  • 3.1K
  • 25 Oct 2022
Topic Review
Applications of Natural Polymers-Based Materials
Natural polymers have emerged as promising candidates for the sustainable development of materials in areas ranging from food packaging and biomedicine to energy storage and electronics. 
  • 3.1K
  • 06 Jan 2022
Topic Review
Multivariate Mutual Information
In information theory there have been various attempts over the years to extend the definition of mutual information to more than two random variables. The expression and study of multivariate higher-degree mutual-information was achieved in two seemingly independent works: McGill (1954) who called these functions “interaction information”, and Hu Kuo Ting (1962) who also first proved the possible negativity of mutual-information for degrees higher than 2 and justified algebraically the intuitive correspondence to Venn diagrams .
  • 3.1K
  • 18 Oct 2022
Topic Review
Carbon-Burning Process
The carbon-burning process or carbon fusion is a set of nuclear fusion reactions that take place in the cores of massive stars (at least 8 [math]\displaystyle{ \begin{smallmatrix}M \odot\end{smallmatrix} }[/math] at birth) that combines carbon into other elements. It requires high temperatures (> 5×108 K or 50 keV) and densities (> 3×109 kg/m3). These figures for temperature and density are only a guide. More massive stars burn their nuclear fuel more quickly, since they have to offset greater gravitational forces to stay in (approximate) hydrostatic equilibrium. That generally means higher temperatures, although lower densities, than for less massive stars. To get the right figures for a particular mass, and a particular stage of evolution, it is necessary to use a numerical stellar model computed with computer algorithms. Such models are continually being refined based on nuclear physics experiments (which measure nuclear reaction rates) and astronomical observations (which include direct observation of mass loss, detection of nuclear products from spectrum observations after convection zones develop from the surface to fusion-burning regions – known as dredge-up events – and so bring nuclear products to the surface, and many other observations relevant to models).
  • 3.1K
  • 17 Nov 2022
Topic Review Peer Reviewed
Local Government Emergency Management
According to the U.S. Federal Emergency Management Agency (FEMA), emergency management is “charged with creating the framework within which communities reduce vulnerability to threats/hazards and cope with disasters” (FEMA, n.d.). Local government emergency management involves the efforts of municipalities, cities, counties, and special government entities in responding to threats/hazards and coping with emergencies.
  • 3.1K
  • 10 Jan 2023
Topic Review
Modes of Pulsed Laser Ablation in Liquid
Pulsed laser ablation in liquid (PLAL) is a physical and top-down approach used to fabricate nanoparticles (NPs). NPs have better physicochemical properties than their bulk counterparts. 
  • 3.1K
  • 14 Feb 2023
Topic Review
Ganoderma lucidum
Ganoderma lucidum has a long history of medicinal uses in the Far East countries of more than 2000 years due to its healing properties. Recently, G. lucidum has come under scientific scrutiny to evaluate its content of bioactive components that affect human physiology and has been exploited for potent components in the pharmacology, nutraceuticals, and cosmetics industries. For instance, evidence is accumulating on the potential of this mushroom species as a promising antiviral medicine for treating many viral diseases, such as dengue virus, enterovirus 71, and recently coronavirus disease of 2019 (COVID-19). Still, more research studies on the biotherapeutic components of G. lucidum are needed to ensure the safety and efficiency of G. lucidum and promote the development of commercial functional foods.
  • 3.1K
  • 11 Apr 2022
Topic Review
Education on Renewable Energy in Secondary Schools
Education is key to advancing a society that can achieve the Sustainable Development Goals (SDGs). One SDG is shifting energy consumption from fossil fuels to renewable energy (RE) sources to reduce environmental damage and prevent global warming. Awareness must be instilled among citizens at an early age (as early as secondary school) to motivate students to pursue higher education and careers in RE concepts and technologies.
  • 3.1K
  • 25 Jul 2022
Topic Review
Effect of Nitrogen Fertilizers on Rhizobium
Nitrogen fixation has the potential to address the global protein shortage by increasing nitrogen supply in agriculture. However, the excessive use of synthetic fertilizers has led to environmental consequences and high energy consumption. To promote sustainable agriculture, alternative approaches such as biofertilizers that utilize biological nitrogen fixation have been introduced to minimize ecological impact. Understanding the process of biological nitrogen fixation, where certain bacteria convert atmospheric nitrogen into ammonia, is crucial for sustainable agriculture. This knowledge helps reduce reliance on synthetic fertilizers and maintain soil fertility. The symbiotic relationship between Rhizobium bacteria and leguminous plants plays a vital role in sustainable agriculture by facilitating access to atmospheric nitrogen, improving soil fertility, and reducing the need for chemical fertilizers.
  • 3.1K
  • 19 Dec 2023
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