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Topic Review
Protective Strategies for Magnesium Alloy Vascular Stents
Magnesium alloy stents have been extensively studied in the field of biodegradable metal stents due to their exceptional biocompatibility, biodegradability and excellent biomechanical properties. Nevertheless, the specific in vivo service environment causes magnesium alloy stents to degrade rapidly and fail to provide sufficient support for a certain time. 
  • 1.2K
  • 05 Jan 2024
Topic Review
Regenerated Keratin-Based Biofilms
The recycling, development, and application of keratin-containing waste (e.g., hair, wool, feather, and so on) provide an important means to address related environmental pollution and energy shortage issues. The extraction of keratin and the development of keratin-based functional materials are key to solving keratin-containing waste pollution. Keratin-based biofilms are gaining substantial interest due to their excellent characteristics, such as good biocompatibility, high biodegradability, appropriate adsorption, and rich renewable sources, among others. At present, keratin-based biofilms are a good option for various applications, and the development of keratin-based biofilms from keratin-containing waste is considered crucial for sustainable development. 
  • 1.2K
  • 28 Nov 2022
Topic Review
Poly(3-hydroxybutyrate) Nanocomposites with Cellulose Nanocrystals
Poly(3-hydroxybutyrate) (PHB) is one of the most promising substitutes for the petroleum-based polymers used in the packaging and biomedical fields due to its biodegradability, biocompatibility, good stiffness, and strength, along with its good gas-barrier properties. One route to overcome some of the PHB’s weaknesses, such as its slow crystallization, brittleness, modest thermal stability, and low melt strength is the addition of cellulose nanocrystals (CNCs) and the production of PHB/CNCs nanocomposites. Choosing the adequate processing technology for the fabrication of the PHB/CNCs nanocomposites and a suitable surface treatment for the CNCs are key factors in obtaining a good interfacial adhesion, superior thermal stability, and mechanical performances for the resulting nanocomposites. 
  • 1.2K
  • 20 May 2022
Topic Review
Cellulose Coarse-Grained
Cellulose is the most common biopolymer and widely used in our daily life. Due to its unique properties and biodegradability, it has been attracting increased attention in the recent years and various new applications of cellulose and its derivatives are constantly being found. The development of new materials with improved properties, however, is not always an easy task, and theoretical models and computer simulations can often help in this process.
  • 1.2K
  • 27 Apr 2021
Topic Review
Carbon-Based Materials for CO2 Adsorption and Conversion
The UN Climate Change Conference in Glasgow (COP26) has stressed that stakeholders need to work together to achieve a NetZero target. Technologies involving absorbents for the capture of CO2 from a gas mixture are energy-intensive. Carbon adsorption and conversion (CAC) approaches have been gaining attention since these technologies can mitigate CO2 emissions.
  • 1.2K
  • 06 Jul 2023
Topic Review
History of Cellulose in Science and Technology
In the history of cellulose chemistry, hydrogen bonding has been the predominant explanation when discussing intermolecular interactions between cellulose polymers. This is unfortunately the general consensus in scholarly textbooks and in many research articles, and it applies to several other biomacromolecules’ interactions as well. The amphiphilicity of cellulose and many other biopolymers, and thereby hydrophobic interactions, has to be taken into account to get a more complete picture.
  • 1.2K
  • 25 May 2023
Topic Review
Functionalization of Long-Period Fiber Grating-Based Biosensors
Long-period fiber grating (LPFG)-based biosensors are being increasingly proposed due to their intrinsic advantages over conventional sensors, including their compactness, potential remote control and immunity to electromagnetic interference. When designing a biosensor, it is a key technological step to select the sensitive material suitable for the biological target. Therefore, the functionalization of LPFG-based biosensor is a fundamental step in realizing biochemical applications. Several common functionalization methods are introduced in detailed, such as covalent immobilization of 3-aminopropyltriethoxysilane silanization and graphene oxide  functionalization, and noncovalent immobilization of layer-by-layer assembly method.
  • 1.2K
  • 13 Jan 2023
Topic Review
Natural and Synthetic Hydrogels in Wound Healing
The care and rehabilitation of acute and chronic wounds have a significant social and economic impact on patients and global health. This burden is primarily due to the adverse effects of infections, prolonged recovery, and the associated treatment costs. Chronic wounds can be treated with a variety of approaches, which include surgery, negative pressure wound therapy, wound dressings, and hyperbaric oxygen therapy. However, each of these strategies has an array of limitations. The existing dry wound dressings lack functionality in promoting wound healing and exacerbating pain by adhering to the wound. Hydrogels, which are commonly polymer-based and swell in water, have been proposed as potential remedies due to their ability to provide a moist environment that facilitates wound healing. Their unique composition enables them to absorb wound exudates, exhibit shape adaptability, and be modified to incorporate active compounds such as growth factors and antibacterial compounds. 
  • 1.2K
  • 08 Jan 2024
Topic Review
Periodontal and Peri-Implant Regeneration
Periodontal and peri-implant regeneration is the technique that aims to restore the damaged tissue around teeth and implants. They are surrounded by a different apparatus, and according to it, the regenerative procedure can differ for both sites. During the last century, several biomaterials and biological mediators were proposed to achieve a complete restoration of the damaged tissues with less invasiveness and a tailored approach.
  • 1.2K
  • 17 Jan 2022
Topic Review
DNA-Based Artificial Transmembrane Channels for Biomedical Applications
Biomolecular channels on the cell membrane are essential for transporting substances across the membrane to maintain cell physiological activity. Artificial transmembrane channels used to mimic biological membrane channels can regulate intra/extracellular ionic and molecular homeostasis, and they elucidate cellular structures and functionalities. Due to their program design, facile preparation, and high biocompatibility, DNA nanostructures have been widely used as scaffolds for the design of artificial transmembrane channels and exploited for ionic and molecular transport and biomedical applications. DNA-based artificial channels can be designed from two structural modules: DNA nanotubes/nanopores as transport modules for mass transportation and hydrophobic segments as anchor modules for membrane immobilization. 
  • 1.2K
  • 19 Mar 2024
Topic Review
Antimicrobial Properties of Plant Fibers
Healthcare-associated infections (HAI), or nosocomial infections, are a global health and economic problem in developed and developing countries, particularly for immunocompromised patients in their intensive care units (ICUs) and surgical site hospital areas. Recurrent pathogens in HAIs prevail over antibiotic-resistant bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. For this reason, natural antibacterial mechanisms are a viable alternative for HAI treatment. Natural fibers can inhibit bacterial growth, which can be considered a great advantage in these applications.
  • 1.2K
  • 29 Nov 2022
Topic Review
Optical Waveguide Layers Fabrication Methods
Several eye-catching techniques have been developed to implement high-quality optical thin films for light-guiding applications. Thin films are the foundation for innovative technologies in various areas, including optical devices, environmental applications, telecommunications devices, and energy storage devices. The morphology and reliability of thin films are critical issues in all applications. Deposition techniques have a major influence on thin-film morphology. Physical and chemical deposition methods can be used to deposit high-quality thin films. A thin film is a thin layer of material with a thickness ranging from a few nm to a few μm. Thin films, like all materials, are classified as amorphous or polycrystalline based on the preparation conditions and the quality of the target material. Glass WGs display highly attractive properties due to the straightforward technology, the low propagation losses, and the flexible index matching to glass fibers. It is highly desirable to have low-loss glasses, reliable and enabling low-cost WG fabrication procedures. An overall requirement is that manufacturing technologies are proficient in high yield, and have guaranteed duplicability within the quantified tolerances, and fundamentally low operating costs.
  • 1.2K
  • 12 Jul 2022
Topic Review
Self-Healing Concrete
The production of cement accounts for 5 to 7% of carbon dioxide emissions in the world, and its broad-scale use contributes to climate imbalance. As a solution, biotechnology enables the cultivation of bacteria and fungi for the synthesis of calcium carbonate as one of the main constituents of cement. Through biomineralization, which is the initial driving force for the synthesis of compounds compatible with concrete, and crystallization, these compounds can be delivered to cracks in concrete. Microencapsulation is a method that serves as a clock to determine when crystallization is needed, which is assisted by control factors such as pH and aeration. 
  • 1.2K
  • 15 Feb 2023
Topic Review
Biochar and Cementitious Composites
Cementitious materials are one of the most used infrastructure materials worldwide due to their low cost, well-developed production methods, and well adaptability to varying environmental conditions. Cementitious composites are mainly divided into three groups, i.e., concrete, mortar and paste. Being quasi brittle, they are prone to cracking, which greatly compromises their strength and durability. Due significance has been given to mitigate the brittle behavior of cementitious composites in the past: Various studies are available, intended at improving the tensile strain capacity of the cementitious materials. Apart from conventional steel reinforcement, inclusion of fibers has remained the focus of many studies.
  • 1.2K
  • 21 Jun 2021
Topic Review
Photoresponsive Biomaterials
Photoresponsive biomaterials have garnered increasing attention due to their ability to dynamically regulate biological interactions and cellular behaviors in response to light. Photoresponsive biomaterials are created by integrating photoresponsive molecules, such as spiropyrans, azobenzenes, hydrazones, and diarylethenes, into biomaterials like hydrogels, nanoparticles, or scaffolds. 
  • 1.2K
  • 16 May 2023
Topic Review Peer Reviewed
Solid Lipid Nanoparticles
Solid lipid nanoparticles (SLNs) are produced from physiologically biocompatible lipids. They have been proven to improve solubility, cellular uptake, and stability, reduce enzyme degradation, and prolong the circulation time of various drugs. SLNs have been applied in the oral, parenteral, transdermal, intranasal, ocular, and pulmonary drug delivery of different drugs, with enhanced safety, bioavailability, and overall therapeutic effects. In this entry, the authors summarize the primary features of SLNs, methods to prepare SLNs, and recent applications of SLNs in drug delivery. Owing to their advantages, SLNs are potential drug delivery systems to improve the management of various diseases and will, soon, be available for clinical use. 
  • 1.2K
  • 24 May 2022
Topic Review
Electrospun Scaffolds for Tissue Engineering
Electrospun fiber scaffolds offer distinct characteristics, including a high surface area-to-volume ratio, excellent porosity, fiber uniformity, compositional diversity, flexibility, and the ease of functionalization with bioactive molecules. These scaffolds can effectively control the release rate of bioactive molecules, making them promising candidates for delivering antibiotics, proteins, and growth factors.
  • 1.2K
  • 08 Aug 2023
Topic Review
Biomimetic Approaches in Clinical Endodontics
Endodontics is an important sub-branch of dentistry which deals with the different conditions of pulp to prevent tooth loss. Traditionally, common procedures, namely pulp capping, root canal treatment, apexification, and apexigonesis, have been considered for the treatment of different pulp conditions using selected materials. However, clinically to regenerate dental pulp, tissue engineering has been advocated as a feasible approach. New trends are emerging in terms of regenerative endodontics which have led to the replacement of diseased and non-vital teeth into the functional and healthy dentine-pulp complex. Root- canal therapy is the standard management option when dental pulp is damaged irreversibly. This treatment modality involves soft-tissue removal and then filling that gap through the obturation technique with a synthetic material. The formation of tubular dentine and pulp-like tissue formation occurs when stem cells are transplanted into the root canal with an appropriate scaffold material. To sum up tissue engineering approach includes three components: (1) scaffold, (2) differentiation, growth, and factors, and (3) the recruitment of stem cells within the pulp or from the periapical region.
  • 1.2K
  • 31 Jan 2023
Topic Review
Milk Whey Hydrolysates as High Value-Added Natural Polymers
There are two types of milk whey obtained from cheese manufacture: sweet and acid. It retains around 55% of the nutrients of the milk. Milk whey is considered as a waste, creating a critical pollution problem, because 9 L of whey are produced from every 10 L of milk. Some treatments such as hydrolysis by chemical, fermentation process, enzymatic action, and green technologies (ultrasound and thermal treatment) are successful in obtaining peptides from protein whey. Milk whey peptides possess excellent functional properties such as antihypertensive, antiviral, anticancer, immunity, and antioxidant, with benefits in the cardiovascular, digestive, endocrine, immune, and nervous system.
  • 1.2K
  • 27 Apr 2022
Topic Review
Prospect Biomedical Applications of Novel Functional Metallic Glasses
The continuous development of novel materials for biomedical applications is resulting in an increasingly better prognosis for patients. The application of more advanced materials relates to fewer complications and a desirable higher percentage of successful treatments. New, innovative materials being considered for biomedical applications are metallic alloys with an amorphous internal structure called metallic glasses. They are currently in a dynamic phase of development both in terms of formulating new chemical compositions and testing their properties in terms of intended biocompatibility. 
  • 1.2K
  • 28 Nov 2022
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