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Topic Review
Karl Barth on Creation-care
At the height of the current pandemic, this article seeks to explore the identity of the Creator God in Karl Barth’s doctrine of creation. Attention is given to his understanding of the eternal covenant God has made with humanity and how we are cared for within a covenantal fellowship. The study also concerns itself with how Barth’s distaste for the notion of analogia entis is somewhat unsustained in his treatment of creation. I argue that, to some extent, the analogy of being vis-à-vis the cosmos is complementarily employed with analogia fides in Barth’s articulation of creation care. This is the case as he reconfigures the talk on creation rigidly in and through Jesus Christ as Creator and creature.
  • 1.2K
  • 30 Sep 2021
Topic Review
Biomarkers of Coronary Artery Plaques
Causing more than 1.8 million deaths a year worldwide, acute coronary syndrome (ACS) represents a major global health burden. It has so far been well-established that most of the plaques leading to ACS are not a result of gradual narrowing of the vessel lumen, but rather a result of sudden disruption of vulnerable atherosclerotic plaques. Apart from various imaging modalities, multiple biomarkers were proposed to identify the presence of vulnerable plaques or plaques at different stages of remodeling. A logic behind measurement of biomarkers in blood that reflect the presence of vulnerable plaque is dual. Certain molecules could arise as a consequence of leakage from unstable plaques, whereas others could merely indicate that a patient is susceptible to the development of a vulnerable plaque as those molecules are implicated in plaque destabilization.
  • 1.2K
  • 30 Jun 2021
Topic Review
EndMT
Endothelial mesenchymal transition (EndMT) is a complex biological process in which endothelial cells lose their specific markers, such as vascular endothelial cadherin (VE-cadherin), and acquire a mesenchymal or myofibroblastic phenotype, expressing specific products, such as α-smooth muscle actin (α-SMA) and type I collagen.
  • 1.2K
  • 02 Jul 2021
Topic Review
LRRK2 in Parkinson’s Disease
LRRK2 is a large (2527 amino acids, 286 kDa), multidomain protein, that bears two enzymatic functions: kinase and GTPase, and several protein-protein interaction domains. Numerous genomic LRRK2 variants have been repeatedly confirmed as pathogenic in Parkinson's Disease (PD). Inhibition of LRRK2 was shown to rescue neurite shortening caused by PD mutations in this protein. This entry discusses possible ways of targetting LRRK2 as potential treatment for PD.
  • 1.2K
  • 09 Aug 2021
Topic Review
Microdosing in Business
Abusing psychoactive substances has been a popular sport in the business world since the mid-19th century. First, they were appreciated for their stimulating or tonic effects, but later with psychedelics on the scene, their importance in subculture matured. In the last decade, it has become very popular to use LSD and cocaine in subtle doses, which provides users with a high that is enough to feel their psychoactive potential, but not as high that significant behavioral changes can be seen. Unlike regular use, microdosing is usually sufficient to affect a few without undue finish and withdrawal symptoms. It allows for abuse in the regular mode of the working week with a rest phase on the weekend. The diametric difference between the abuse of standard dosing and micro-dosing is also in the decreasing tolerance of the organism.
  • 1.2K
  • 29 Mar 2022
Topic Review
Effects of Microwaves, Ultrasonication, and Thermosonication on Milk
Cow’s milk is considered an excellent protein source. However, the digestibility of milk proteins needs to be improved. The milk protein content was reduced as the microwave processing time and the temperature increased. The final milk protein available in the sample was lower when microwave processing was conducted at 75 °C and 90 °C compared to 60 °C, whereas the ultrasound treatment significantly improved the protein content, and no particular trend was observed for the thermosonicated samples. Thus, ultrasound processing shows a potential application in improving the protein quality of cow’s milk.
  • 1.2K
  • 13 Jan 2022
Topic Review
Lung Cancer: Genotype Prediction in Computer-Aided Decision Systems
Genotype studies are the fundamental keys in the development of personalized medicine in lung cancer and they enable the progress of targeted therapies. Furthermore, gene analysis allows to identify biomarkers that can be used for early cancer detection, predict the prognosis and the response to the treatment plans, and monitor disease progression.
  • 1.2K
  • 27 Apr 2022
Topic Review
Oscillation of Solutions for Fractional Difference Equations
Oscillation is one of the important branches in applied mathematics and can be induced or destroyed by the introduction of nonlinearity, delay, or a stochastic term. The oscillation of differential and difference equations contributes to many realistic applications, such as torsional oscillations, the oscillation of heart beats, sinusoidal oscillation, voltage-controlled neuron models, and harmonic oscillation with damping. 
  • 1.2K
  • 29 Apr 2022
Topic Review
Mycomerge: Mycelium-Based NFRC on A Rattan Framework
Counteracting the usual fabrication techniques, the proposed design method aims to guide mycelium’s growth on a natural rattan framework that serves as a supportive structure for the mycelium substrate and its fiber reinforcement. The rattan skeleton is integrated into the finished composite product, forming a fully biodegradable unit, which can support a load beyond 20 times its own weight. 
  • 1.2K
  • 12 May 2022
Topic Review
Agrivoltaics in Ontario Canada
Well-intentioned regulations to protect Canada’s most productive farmland restrict large-scale solar photovoltaic (PV) development. The recent innovation of agrivoltaics, which is the co-development of land for both PV and agriculture, makes these regulations obsolete. Burgeoning agrivoltaics research has shown agricultural benefits, including increased yield for a wide range of crops, plant protection from excess solar energy and hail, and improved water conservation, while maintaining agricultural employment and local food supplies. In addition, the renewable electricity generation decreases greenhouse gas emissions while increasing farm revenue.  The background on Ontario land-use Policy and policy recommendations about agrivoltaics are discussed. 
  • 1.2K
  • 05 Aug 2022
Topic Review
Gee Bee Model R
The Gee Bee Model R Super Sportster was a special purpose racing aircraft made by Granville Brothers Aircraft of Springfield, Massachusetts at the now-abandoned Springfield Airport (Massachusetts). Gee Bee stands for Granville Brothers.
  • 1.2K
  • 02 Nov 2022
Topic Review
Dignity Taking
Dignity taking is the destruction or confiscation of property rights from owners or occupiers, where the intentional or unintentional outcome is dehumanization or infantilization. There are two requirements: (1) involuntary property destruction or confiscation and (2) dehumanization or infantilization. Dehumanization is “the failure to recognize an individual or group’s humanity” and infantilization is “the restriction of an individual or group’s autonomy based on the failure to recognize and respect their full capacity to reason.” Evidence of a dignity taking can be established empirically through either a top-down approach, examining the motive and intent behind those who initiated the taking, or a bottom-up approach, examining the viewpoints of dispossessed people. When this larger harm called a dignity taking occurs, mere reparations (or compensation for physical things taken) are not enough. Dignity restoration is required. Dignity restoration is a remedy that seeks to provide dispossessed individuals and communities with material compensation through processes that affirm their humanity and reinforce their agency. In practical terms, the remedial process places dispossessed individuals or communities in the driver’s seat and gives them a significant degree of autonomy in deciding how they are made whole. The dignity takings/dignity restoration framework was first created by Professor Bernadette Atuahene following her empirical exploration of land dispossession and restitution in South Africa in her book, We Want What’s Ours: Learning from South Africa’s Restitution Program (Oxford University Press 2014). Since then, many scholars across disciplines have applied these socio-legal concepts to an array of case studies in various time periods and geographic locations, providing a transnational, historicized approach to understanding involuntary property loss and its material and non-material consequences. The dignity takings/dignity restoration framework provides a lexicon to describe and analyze property takings from poor and vulnerable populations across the globe in different historical periods; focuses on redress by linking events of property dispossession to highlight opportunities for learning, resistance, and solidarity; allows people who are not property scholars to participate in the conversation about involuntary property loss and adequate remedies; captures the both the material and immaterial consequences of property confiscation; and inserts dignity into the scholarly discourse about property, countering the singular focus on efficiency, which has dominated legal analysis since the ascendancy of law and economics.
  • 1.2K
  • 30 Nov 2022
Topic Review
Phytopharmaceutical Formulations and Other Uses of Moringa oleifera
Moringa oleifera, also known as the “tree of life” or “miracle tree,” is classified as an important herbal plant due to its immense medicinal and non-medicinal benefits. The plant is used to cure wounds, pain, ulcers, liver disease, heart disease, cancer, and inflammation. 
  • 1.2K
  • 13 Feb 2023
Topic Review
Behavioral and Psychiatric Observations in Autism
Autism spectrum disorder (ASD) consists of a group of heterogeneous genetic neurobehavioral disorders associated with developmental impairments in social communication skills and stereotypic, rigid or repetitive behaviors. Behavioral and psychiatric disorders are more prevalent in autistic individuals compared to the general population, and their symptom overlap with core features of autism can create diagnostic challenges. 
  • 1.2K
  • 03 Apr 2023
Topic Review
The Role of Calcium in Cytosolic Protein-Mediated Apoptosis
Calcium is an essential intracellular messenger that plays a vital role in controlling a broad range of cellular processes, including apoptosis. Cytosolic calcium levels are tightly regulated, and an imbalance in calcium concentrations can trigger apoptosis through various mechanisms involving cytosolic proteins.
  • 1.2K
  • 30 May 2023
Topic Review
Potential Pharmacological Effects of Lucidenic Acids
Ganoderma lucidum has long been used as a multi-purpose plant and functional food. The pharmacological properties of G. lucidum are primarily attributed to its polysaccharides and triterpenoids. Ganoderic and lucidenic acids are the two major triterpenoids groups in G. lucidum. Despite the discovery of 22 types of lucidenic acids, research on lucidenic acids is significantly less extensive compared to that on ganoderic acid. 
  • 1.2K
  • 14 Jul 2023
Topic Review
LaAlO3-Based Solid Oxide Fuel Cell Electrolytes
Solid oxide fuel cells (SOFCs) are efficient electrochemical devices that allow for the direct conversion of fuels (their chemical energy) into electricity. Although conventional SOFCs based on yttria-stabilized zirconia (YSZ) electrolytes are widely used from laboratory to commercial scales, the development of alternative ion-conducting electrolytes is of great importance for improving SOFC performance at reduced operation temperatures. The basic information has been researched (synthesis, structure, morphology, functional properties, applications in SOFCs) on representative family of oxygen-conducting electrolytes, such as doped lanthanum aluminates (LaAlO3).
  • 1.2K
  • 16 Jun 2022
Topic Review
Yersiniabactin and Yersinopine
The pathogenic anaerobic bacteria Yersinia pestis (Y. pestis), which is well known as the plague causative agent, has the ability to escape or inhibit innate immune system responses, which can result in host death even before the activation of adaptive responses. Yersinia pestis produces two metallophores: yersiniabactin, for iron chelation (siderophore), and an opine type metallophore called yersinopine.
  • 1.2K
  • 27 Apr 2023
Topic Review
LGAD-Based Silicon Sensors for 4D Detectors
Low-Gain Avalanche Diodes (LGAD) are a class of silicon sensors developed for the fast detection of Minimum Ionizing Particles (MIPs). The development was motivated by the need of resolving piled-up tracks of charged particles emerging from several vertexes originating from the same bunch-crossing in High-Energy Physics (HEP) collider experiments, which, however, are separated not only in space but also in time by a few tens of picoseconds. Built on thin silicon substrates and featuring an internal moderate gain, they provide fast signals for excellent timing performance, which are therefore useful to distinguish the different tracks. Unfortunately, this comes at the price of poor spatial resolution. To overcome this limitation, other families of LGAD-based silicon sensors which can deliver in the same substrate both excellent timing and spatial information are under development.
  • 1.2K
  • 06 Mar 2023
Topic Review
Thermal Transport in 2D Materials
Two-dimensional materials are characterized by excellent structural, mechanical, and physical properties, making them suitable for basic science and engineering applications because of their superb properties. In nanomaterials, thermal transport has revealed many unique phenomena, which, when understood, will open up new possibilities for the development of new nanotechnologies in thermal management. New technologies have become increasingly dependent on thermal conductivity as an essential parameter. Many benefits can be derived from nanoelectronic devices using 2D materials and they may potentially extend electronics into new fields of application.
  • 1.2K
  • 22 Feb 2023
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