Topic Review
Associations between Childhood Abuse and Adult Psychopathology
Research consistently shows that abuse during childhood is related to adult psychopathology. Adverse childhood experiences, including emotional, physical, and sexual abuse, have been consistently linked to mental health problems in children and adults.
  • 113
  • 05 Mar 2024
Topic Review
Corticosteroids for the Management of Diabetic Macular Edema
Diabetic macular edema (DME) is a common complication of diabetes mellitus and a leading cause of visual impairment worldwide. It is defined as the diabetes-related accumulation of fluid, proteins, and lipids, with retinal thickening, within the macular area. DME affects a significant proportion of individuals with diabetes, with the prevalence increasing with disease duration and severity. Corticosteroids (CSs) are a group of hormones produced by the adrenal cortex.
  • 285
  • 05 Mar 2024
Topic Review
Discovering Amino Acid Transporter Inhibitors
Amino acid transporters are abundant amongst the solute carrier family and have an important role in facilitating the transfer of amino acids across cell membranes. Because of their impact on cell nutrient distribution, they also appear to have an important role in the growth and development of cancer. Naturally, this has made amino acid transporters a novel target of interest for the development of new anticancer drugs. 
  • 97
  • 05 Mar 2024
Topic Review
Applications of Gas Chromatography for Tricyclic Antidepressants Analysis
Tricyclic antidepressant drugs (TCAs) are a main category of antidepressants, which are widely used for the treatment of psychological disorders due to their low cost and their high efficiency. Therefore, there is a great demand for method development for the determination of TCAs in biofluids, especially for therapeutic drug monitoring. Gas chromatography (GC) was the first chromatographic technique implemented for this purpose. With the development in the field of sample preparation, many novel GC applications have been developed. 
  • 141
  • 05 Mar 2024
Topic Review
White Coat in the Domestic Horse
Traits such as shape, size, and color often influence the economic and sentimental value of a horse. Around the world, horses are bred and prized for the colors and markings that make their unique coat patterns stand out from the crowd. The underlying genetic mechanisms determining the color of a horse’s coat can vary greatly in their complexity.
  • 126
  • 05 Mar 2024
Topic Review
Artificial Intelligence Advancements in Cervical Cancer
Artificial intelligence has yielded remarkably promising results in several medical fields, namely those with a strong imaging component. Gynecology relies heavily on imaging since it offers useful visual data on the female reproductive system, leading to a deeper understanding of pathophysiological concepts. The applicability of artificial intelligence technologies has not been as noticeable in gynecologic imaging as in other medical fields. However, due to growing interest in this area, some studies have been performed with exciting results. From urogynecology to oncology, artificial intelligence algorithms, particularly machine learning and deep learning, have shown huge potential to revolutionize the overall healthcare experience for women’s reproductive health.
  • 188
  • 05 Mar 2024
Topic Review
Promoting Health among Children and Adolescents via Gamification
The rapid growth in digital technology usage among children and adolescents has highlighted the need for novel approaches to promote their physical and mental health. Promoting children and adolescents’ physical and mental health through gamified techniques, these interventions can provide an interactive and engaging platform for encouraging physical activity, promoting healthy nutrition, enhancing emotional regulation, and promoting mental health. The significance of this topic stems from the pervasive use of electronic games, beginning at a young age, which makes them popular educational tools.
  • 331
  • 05 Mar 2024
Topic Review
Experimental Approach to Silicon Heterojunction Tandem Solar Cells
A solar cell, or a photovoltaic (PV) cell, is an electrical device that converts light energy directly into electricity by the photovoltaic effect. There are different types of solar cells. Tandem solar cells could have a very good conversion efficiency in comparison with other types of solar cells. Tandem solar cells are considered the industry’s next step in photovoltaics due to their excellent conversion efficiency. A very good example is the perovskite absorber material that has been developed for efficient tandem solar cells. 
  • 182
  • 05 Mar 2024
Topic Review
Novel Biomarkers of Bone Metabolism
Bone represents a metabolically active tissue subject to continuous remodeling orchestrated by the dynamic interplay between osteoblasts and osteoclasts. These cellular processes are modulated by a complex interplay of biochemical and mechanical factors, which are instrumental in assessing bone remodeling. This comprehensive evaluation aids in detecting disorders arising from imbalances between bone formation and reabsorption. Osteoporosis, characterized by a reduction in bone mass and strength leading to heightened bone fragility and susceptibility to fractures, is one of the more prevalent chronic diseases. Some epidemiological studies, especially in patients with chronic kidney disease (CKD), have identified an association between osteoporosis and vascular calcification. Notably, low bone mineral density has been linked to an increased incidence of aortic calcification, with shared molecules, mechanisms, and pathways between the two processes. Certain molecules emerging from these shared pathways can serve as biomarkers for bone and mineral metabolism. Detecting and evaluating these alterations early is crucial, requiring the identification of biomarkers that are reliable for early intervention. While traditional biomarkers for bone remodeling and vascular calcification exist, they suffer from limitations such as low specificity, low sensitivity, and conflicting results across studies. In response, efforts are underway to explore new, more specific biomarkers that can detect alterations at earlier stages. 
  • 148
  • 05 Mar 2024
Topic Review
Connections between Intestinal Flora and Kynurenine Pathway
The intestinal flora has been the focus of numerous investigations recently, with inquiries not just into the gastrointestinal aspects but also the pathomechanism of other diseases such as nervous system disorders and mitochondrial diseases. Mitochondrial disorders are the most common type of inheritable metabolic illness caused by mutations of mitochondrial and nuclear DNA. Metabolites of the kynurenine pathway are linked to many disorders, such as depression, schizophrenia, migraine, and also diseases associated with impaired mitochondrial function. The kynurenine pathway includes many substances, for instance kynurenic acid and quinolinic acid. 
  • 93
  • 05 Mar 2024
  • Page
  • of
  • 5351
Video Production Service