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Topic Review
Enterococcus and COVID-19
Based on the uncontrolled use of antibiotics and the lack of worldwide-accepted healthcare policies, the COVID-19 pandemic has provided the best premises for the emergence of life-threatening infections. Based on changes described in the intestinal microbiome, showing an increased number of Enterococcus bacteria and increased intestinal permeability due to viral infection, infections with Enterococcus have taken the spotlight in the healthcare setting. The COVID-19 pandemic has launched the best premises for the development of highly resistant bacterial strains due to unregulated antimicrobial use and the lack of proper worldwide-accepted protocols. Enterococcus genus represents one of the most common findings in human infections. It is no surprise that during the pandemic, a high number of this type of infection was anticipated.
  • 627
  • 21 Jun 2022
Topic Review
Epimedium Flavonoids
Epimedium is a classical Chinese herbal medicine, which has been used extensively to treat various diseases, such as sexual dysfunction, osteoporosis, cancer, rheumatoid arthritis, and brain diseases. Flavonoids, such as icariin, baohuoside I, icaritin, and epimedin C, are the main active ingredients with diverse pharmacological activities.
  • 387
  • 23 Oct 2023
Topic Review
Escherichia coli Antimicrobial Resistance in Humans
To date, the scientific literature on health variables for Escherichia coli antimicrobial resistance (AMR) has been investigated throughout several systematic reviews, often with a focus on only one aspect of the One Health variables: human, animal, or environment.
  • 273
  • 03 Jan 2024
Topic Review
Escherichia coli-Based Therapeutic Protein Expression
Therapeutic proteins treat many acute and chronic diseases that were, until recently, considered untreatable. However, their high development cost keeps them out of reach of most patients around the world. One possible way to make manufacturing cheaper is to use newer technologies, such as Escherichia coli to make larger molecules, like full-length antibodies, that are normally only made in Chinese Hamster Ovary (CHO) cells, switch to continuous manufacturing, and change the process to cell-free synthesis. The advantages of using E. coli include a shorter production cycle, little risk of viral contamination, cell host stability, and a highly reproducible post-translational modification.
  • 128
  • 08 Dec 2023
Topic Review
Eucalyptus globulus Leaves in Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common neurodegenerative disorder affecting elderly people worldwide. Currently, there are no effective treatments for AD able to prevent disease progression, highlighting the urgency of finding new therapeutic strategies to stop or delay this pathology. Several plants exhibit potential as source of safe and multi-target new therapeutic molecules for AD treatment. Meanwhile, Eucalyptus globulus extracts revealed important pharmacological activities, namely antioxidant and anti-inflammatory properties, which can contribute to the reported neuroprotective effects.
  • 865
  • 17 Aug 2022
Topic Review
Euphorbia neriifolia Linn.
Medicinal plants have considerable potential as antimicrobial agents due to the presence of secondary metabolites. Researchers aim to summarize the classification, morphology, and ethnobotanical uses of Euphorbia neriifolia L. and its derived phytochemicals with the recent updates on the pharmacological properties against emerging infectious diseases, mainly focusing on bacterial, viral, fungal, and parasitic infections. 
  • 1.6K
  • 14 Jul 2022
Topic Review
Euphorbia officinarum L.
Euphorbia officinarum L. is a Moroccan endemic plant known as “Tikiout” and “Daghmus” that can also be found in Mauritania, Western Sahara, and Algeria. This species has been used in folk medicine as anti-diabetic; in the treatment of skin diseases when associated with Opuntia ficus-barbarica, Zea mays and Ziziphus lotus, and honey for eliminating helminths, in the treatment of pyelonephritis and cystitis. Triterpenes, phytosterols and ingol diterpenes have been isolated and identified in the latex of Moroccan E. officinarum, nevertheless the biggest interest has been to obtain derivatives by hemisynthesis from natural triterpenes with insecticidal and antimicrobial activity. In Morocco, the E. officinarum honey is considered the most precious; nevertheless, many times it is mixed with other Euphorbiaceae honeys. To increase the commercial value of a monofloral E. officinarum honey, it would be important to find one or more specific markers for this type of honey to be sure of its authenticity.
  • 520
  • 31 Jan 2023
Topic Review
Ferula sinkiangensis (Chou-AWei, Chinese Ferula)
F. sinkiangensis K.M. Shen (Chou-AWei, Chinese Ferula, (Xinjiang’awei)) is an important member of this genus. F. sinkiangensis is a perennial plant endemic in Xinjiang Uygur Autonomous Region, China.
  • 452
  • 21 Feb 2023
Topic Review
Fleur de sel
As mechanized processes developed, small producers of traditional sea salt ceased to be competitive. However, when the valuable salt flower (a.k.a. fleur de sel, flower of salt) market appeared, it gave new breath to the activity of traditional salt pan production. Salt flower sensitivity and delicateness became a part of modern food habits. Its crystals present some grain differentiation and these can fulfill diversified consumer tastes. In cooking art, a regular fine flower of salt can be used to finish dishes, whereas a longer and thin grain known as ‘scale’ (a.k.a. écaille de fleur de sel in French) can be used for a more gourmet-like palate.
  • 644
  • 03 Aug 2022
Topic Review
Fusarium-Derived Secondary Metabolites with Antimicrobial Effects
Fungal microbes are important in the creation of new drugs, given their unique genetic and metabolic diversity. As one of the most commonly found fungi in nature, Fusarium spp. has been well regarded as a prolific source of secondary metabolites (SMs) with diverse chemical structures and a broad spectrum of biological properties. However, little information is available concerning their derived SMs with antimicrobial effects. By extensive literature search and data analysis, as many as 185 antimicrobial natural products as SMs had been discovered from Fusarium strains by the end of 2022.
  • 239
  • 21 Apr 2023
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