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Topic Review
Biography
Topic Review
Nanozymes
Nanozymes are advanced nanomaterials which possess unique physicochemical properties with the precise structural fabrication capability to mimic intrinsic biologically relevant reactions.
4.0K
19 Jan 2021
Topic Review
Nanozyme-Based Glucose Biofuel Cells
The appearance and evolution of biofuel cells can be categorized into three groups: microbial biofuel cells (MBFCs), enzymatic biofuel cells (EBFCs), and enzyme-like nanomaterial (nanozyme)-based biofuel cells (NBFCs). MBFCs can produce electricity from waste; however, they have significantly low power output as well as difficulty in controlling electron transfer and microbial growth. EBFCs are more productive in generating electricity with the assistance of natural enzymes, but their vulnerability under diverse environmental conditions has critically hindered practical applications.
662
26 Aug 2021
Topic Review
Nanozyme Platforms for Antibacterial Applications
Some key enzymes or classes of enzymes, such as superoxide dismutase (SOD), catalase (CAT), oxidase (OXD), peroxidase (POD), deoxyribonuclease (DNase), etc., have been implicated in antibacterial therapy.
673
21 Jun 2022
Topic Review
Nanotube Functionalization
The carbon nanotubes (CNTs) are modified by different routes, such as covalent and non-covalent modification of the outer surface, the substitution of atoms or the filling of CNT channels. Covalent functionalization (adsorption) requires reactive species that can form covalent adducts with the sp2 carbon of CNT. The main advantage of the covalent functionalization of CNTs is that it is stronger than non-covalent interactions, however, it requires damage to the sidewalls. Unlike non-covalent functionalization, it changes the electronic structure, resulting in the irreversible loss of double bonds. These changes can affect conductivity properties and therefore, some applications.
398
16 Aug 2022
Topic Review
Nanotoxicity in Human Primary and Cancer Cells
Nanomaterial toxicity tests using normal and cancer cells may yield markedly different results. Nanomaterial toxicity between cancer and primary human cells was compared to determine the basic cell line selection criteria for nanomaterial toxicity analyses.
963
31 Mar 2022
Topic Review
Nanotechnology-Based Tumor Tissue-Specific Drug Targeting Delivery Systems
Owing to high efficacy and safety, natural medicines have found their way into the field of cancer therapy over the past few decades. However, the effective ingredients of natural medicines have shortcomings of poor solubility and low bioavailability. Nanoparticles can not only solve the problems above but also have outstanding targeting ability. Targeting preparations can be classified into three levels, which are target tissues, cells, and organelles. On the premise of clarifying the therapeutic purpose of drugs, one or more targeting methods can be selected to achieve more accurate drug delivery and consequently to improve the anti-tumor effects of drugs and reduce toxicity and side effects.
228
12 Dec 2023
Topic Review
Nanotechnology-Based Techniques for Sensing Amino Acids/Peptides/Proteins
Protein, peptide- and amino acid-based drug delivery systems have proficiently transformed nanotechnology via immense flexibility in their features for attaching various drug molecules and biodegradable polymers. In this regard, novel nanostructures including carbon nanotubes, electrospun carbon nanofibers, gold nanoislands, and metal-based nanoparticles have been introduced as nanosensors for accurate detection of these organic compounds. These nanostructures can bind the biological receptor to the sensor surface and increase the surface area of the working electrode, significantly enhancing the biosensor performance.
554
13 Dec 2021
Topic Review
Nanotechnology-Based Bioactive Antifeedant for Plant Protection
An antifeedant approach for insect control in crop management has been comprehensively studied by many researchers, though it has only been restricted to plant-based compounds and to the laboratory level at least. Nano-delivery formulations of biopesticides offer a wide variety of benefits, including increased effectiveness and efficiency with the improved properties of the antifeedant. An antifeedant nano-delivery system can increase their bioactivities, such as increasing sublethal bioactivity or reducing toxicity levels in both crude extracts/essential oils (EOs) and pure compounds.
412
07 Mar 2022
Topic Review
Nanotechnology with Photo- and Radiotherapy for Colorectal Cancer
Colorectal cancer is the third most common cancer worldwide. Despite recent advances in the treatment of this pathology, which include a personalized approach using radio- and chemotherapies in combination with advanced surgical techniques, it is imperative to enhance the performance of these treatments and decrease their detrimental side effects on patients’ health. Nanomedicine is likely the pathway towards solving this challenge by enhancing both the therapeutic and diagnostic capabilities. In particular, plasmonic nanoparticles show remarkable potential due to their dual therapeutic functionalities as photothermal therapy agents and as radiosensitizers in radiotherapy.
279
03 Mar 2023
Topic Review
Nanotechnology Used for Retinoblastoma
Retinoblastoma is a rare type of cancer, and its treatment, as well as diagnosis, is challenging, owing to mutations in the tumor-suppressor genes and lack of targeted, efficient, cost-effective therapy, exhibiting a significant need for novel approaches to address these concerns. For this purpose, nanotechnology has revolutionized the field of medicine with versatile potential capabilities for both the diagnosis, as well as the treatment, of retinoblastoma via the targeted and controlled delivery of anticancer drugs via binding to the overexpressed retinoblastoma gene. Nanotechnology has also generated massive advancements in the treatment of retinoblastoma based on the use of surface-tailored multi-functionalized nanocarriers.
546
22 Sep 2021
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