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Topic Review
Multicomponent Shape-Memory Polymers
Shape-memory polymers (SMPs)  are often combined with other functional materials. For example, polymers, metals, or other inorganic materials, in the shape of particles, fibers, and laminates, are combined to create multicomponent systems. Since these multicomponent systems are built up from discrete phases consisting of SMPs mixed with other polymers at the macroscopic or molecular level or reinforced with other domains (e.g., inorganic particle), they are particularly suited for the realization of multifunctionality.
  • 358
  • 09 Aug 2022
Topic Review
Mucoadhesive and Mucopenetrating Polymer-Based Adjuvants
Mucus is a viscoelastic gel that acts as a protective barrier for epithelial surfaces. The mucosal vehicles and adjuvants need to pass through the mucus layer to make drugs and vaccine delivery by mucosal routes possible. The mucoadhesion of polymer particle adjuvants significantly increases the contact time between vaccine formulations and the mucosa; then, the particles can penetrate the mucus layer and epithelium to reach mucosa-associated lymphoid tissues.
  • 337
  • 23 May 2023
Topic Review
Molecularly Imprinted Polymers
Molecularly imprinted polymers (MIPs) are synthetic recognition materials obtained by the polymerisation of functional and cross-linking monomers in the presence of a template. MIPs are attractive not only for their recognition properties that are close to those of natural receptors and their availability for a wide range of targets but also for their superior chemical and physical stability compared to biological receptors. 
  • 1.2K
  • 10 Jun 2021
Topic Review
Molecularly Imprinted Polydopamine in Sensing Applications
Molecularly imprinted polymers (MIPs) are synthetic receptors that mimic the specificity of biological antibody–antigen interactions. By using a “lock and key” process, MIPs selectively bind to target molecules that were used as templates during polymerization. While MIPs are typically prepared using conventional monomers, such as methacrylic acid and acrylamide, contemporary advancements have pivoted towards the functional potential of dopamine as a novel monomer. The overreaching goal of the proposed review is to fully unlock the potential of molecularly imprinted polydopamine (MIPda) within the realm of cutting-edge sensing applications. 
  • 152
  • 19 Oct 2023
Topic Review
Molecular Weight of Polyamides
Polyamides (PAs) undergo local environmental degradation, leading to a decline in their mechanical properties over time. PAs can experience various forms of degradation, such as thermal degradation, oxidation, hydrothermal oxidation, UV oxidation, and hydrolysis. In order to better comprehend the degradation process of PAs, it is crucial to understand each of these degradation mechanisms individually.
  • 539
  • 09 Jan 2024
Topic Review
Modified Starch-Based Adhesives
Consumer trends towards environmentally friendly products are driving plastics industries to investigate more benign alternatives to petroleum-based polymers. In the case of adhesives, one possibility to achieve sustainable production is to use non-toxic, low-cost starches as biodegradable raw materials for adhesive production. While native starch contains only hydroxyl groups and has limited scope, chemically modified starch shows superior water resistance properties for adhesive applications. Esterified starches, starches with ester substituents, can be feasibly produced and utilized to prepare bio-based adhesives with improved water resistance. Syntheses of esterified starch materials can involve esterification, transesterification, alkylation, acetylation, succinylation, or enzymatic reactions.
  • 2.5K
  • 31 May 2022
Topic Review
Modification of Glucomannan as an Excipient
Glucomannan (GM) is a polysaccharide generally extracted from the tuber of Amorphophallus konjac. It consists of mannose and glucose residues linked by β-(1-4) and exhibits hydrocolloid characteristics which can be applied as thickening and gelling agents. However, it has poor water resistance and low mechanical strength when used as an excipient in solid form. Several physical and chemical modifications have been carried out to improve these drawbacks. Chemical modification involves the substitution of functional groups in GM’s structure including esterification and etherification. It causes a decrease in its high hydrophilic film behavior and produce water-resistant films. Physical modification involves mixing native GM with other excipients through processes involving milling, moisture, temperature, pressure, radiation, etc. It causes variations to particle size, shape, surface properties, porosity, density, and to functional properties such as swelling capacity and gelation ability
  • 732
  • 26 Jul 2022
Topic Review
Mixed-Matrix Membranes for Gas Separation
Nanocomposite membranes, obtained by dispersing solid particles within a polymeric matrix, are referred to as mixed-matrix membranes (MMMs) and are potentially capable to exceed the trade-off restrictions between membrane permeability and selectivity, that is an intrinsic trait for polymeric membranes applied to gas separation. Making the most appropriate combination of filler and polymer is an exciting challenge for materials scientists.
  • 1.0K
  • 28 Jan 2022
Topic Review
MIPs Preparation by Computational Simulation–Aided
Molecularly imprinted polymers (MIP) are obtained by initiating the polymerization of functional monomers surrounding the template molecule in the presence of crosslinkers and porogens. Usually the best adsorption performance can be obtained by optimizing the polymerization conditions, but the process is time-consuming and labor-intensive. At the same time, the use of a large number of organic reagents in the process of experimental optimization also limits the development and promotion of molecular imprinting technology. Theoretical calculation based on calculation simulation and intermolecular force is an effective method to solve this problem because it is convenient, versatile, environmentally friendly and low in price. It is not affected by the space environment, and the calculation efficiency is high.
  • 696
  • 27 Aug 2021
Topic Review
MIP Application for the Detection of Infectious Diseases
Molecularly imprinted polymer (MIP)-based biosensors have enormous potential for disease detection. Infectious diseases can be detected and identified using MIPs, which are imprinted with whole viruses or specific proteins—biomarkers. Simple detection of the virus can be achieved by whole virus surface imprinting because viruses are easily identified by their morphology and surface properties. Other imprinting techniques and related sensitivity of the prepared MIP-based sensors are bulk imprinting, soft lithography, self-assembly, and the particle core-shell (template immobilization technique). Using MIP-based technology, viruses can be detected by a whole virus, as in the case of the Japanese encephalitis virus imprinted in the tetraethyl orthosilicate or hepatitis A virus imprinted in polydopamine (PDA), virus aptamer (e.g., HIV-1 gene imprinted in poly(o-phenylenediamine on ITO), main protein (e.g., spike protein or NS1 (non-structural protein 1—a specific and sensitive biomarker for dengue virus infection) or HIV-p24 (human immunodeficiency virus p24)), epitope (e.g., glycoprotein 41, gp41 (of related protein to human immunodeficiency virus type 1 (HIV-1))) templates. 
  • 325
  • 03 Jul 2023
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