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Topic Review
Biosensors for the Detection of L-Amino Acids
The field of biosensors is filled with reports and designs of various sensors, with the vast majority focusing on glucose sensing. However, in addition to glucose, there are many other important analytes that are worth investigating as well. In particular, L-amino acids appear as important diagnostic markers for a number of conditions. The need to determine L-amino acids from clinical samples has risen. More clinical data appear to demonstrate that abnormal concentrations of L-amino acids are related to various clinical conditions such as inherited metabolic disorders, dyslipidemia, type 2 diabetes, muscle damage, etc.
  • 266
  • 03 Jan 2024
Topic Review
Nutritional Strategies to Mitigate Post-Weaning Challenges in Pigs
The pig-farming industry faces significant challenges in ensuring the health and growth of piglets, particularly during the weaning phase. This critical period involves multiple stressors, such as environmental changes, dietary shifts, and social separation, which can adversely affect the piglet’s digestive health, immune system, and overall well-being.
  • 478
  • 02 Jan 2024
Topic Review
Fundamentals of Covalent Organic Frameworks Based Electrochemical Sensors
The international community has been paying close attention to the issue of food safety as a matter of public health. The presence of a wide range of contaminants in food poses a significant threat to human health, making it vital to develop detection methods for monitoring these chemical contaminants. Electrochemical sensors using emerging materials have been widely employed to detect food-derived contaminants. Covalent organic frameworks (COFs) have the potential for extensive applications due to their unique structure, high surface area, and tunable pore sizes.
  • 255
  • 02 Jan 2024
Topic Review
Tryptophan and Proline Oxidation Products in Adipokinetic Hormones
Adipokinetic hormones (AKHs) regulate important physiological processes in insects. AKHs are short peptides with blocked termini and Trp in position 8. Often, proline occupies position 6. Few post-translational modifications have been found, including hydroxyproline ([Hyp6]) and kynurenine (Kyn). Researchers' latest data suggest that the Hyp- and Kyn-containing AKHs occur more often than originally thought and researchers investigated if they are natural or artifactual. Experimental evidence indicated that Hyp occurs endogenously in insect corpora cardiaca.
  • 242
  • 02 Jan 2024
Topic Review
Kaempferol- and Quercetin-Rich Herbs in Alzheimer’s Disease Treatment
Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder impairing cognition and memory in the elderly. This disorder has a complex etiology, including senile plaque and neurofibrillary tangle formation, neuroinflammation, oxidative stress, and damaged neuroplasticity. The treatment options are limited, so alternative treatments such as herbal medicine could suppress symptoms while slowing cognitive decline.
  • 695
  • 02 Jan 2024
Topic Review
Oligonucleotides as Therapeutic Agents
Nucleic acids have emerged as powerful biomaterials, revolutionizing the field of biomedicine. Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), possess unique properties such as molecular recognition ability, programmability, and ease of synthesis, making them versatile tools in biosensing and for gene regulation, drug delivery, and targeted therapy.
  • 279
  • 02 Jan 2024
Topic Review
Hemp-Derived CBD Used in Food and Food Supplements
Cannabis sativa L., a plant historically utilized for textile fibers, oil, and animal feed, is progressively being recognized as a potential food source.
  • 316
  • 02 Jan 2024
Topic Review
Post-Harvest Technological Advances and Ripening Techniques for Peach
Post-harvest handling and ripening techniques have an impact on peach quality and shelf life, which has a big impact on consumer satisfaction and market competitiveness.
  • 257
  • 02 Jan 2024
Topic Review
Plant Toxins: Recombinant Production as Components of Immunotoxins
Plant toxins that target eukaryotic 28S ribosomal RNA (Ribosome Inactivating Proteins, RIPs), such as the catalytic (A) chain of ricin (a dimeric A-B toxin from Ricinus communis) and saporin (a single chain A toxin from Saponaria officinalis), have found widespread use in the construction of immunotoxins. Both these toxins depurinate ribosomal 28S RNA at a specific site (GAGA loop) inhibiting the binding of elongation factor 2 and blocking protein synthesis. Their high toxicity towards eukaryotic cells has thus justified their use as components of chimeric toxins in cancer treatment. A brief description of recombinant RIPs production is given.
  • 173
  • 02 Jan 2024
Topic Review
Auxin Signaling by Smut Fungi during Plant Colonization
A common feature of many plant-colonizing organisms is the exploitation of plant signaling and developmental pathways to successfully establish and proliferate in their hosts. Auxins are central plant growth hormones, and their signaling is heavily interlinked with plant development and immunity responses. Smuts, as one of the largest groups in basidiomycetes, are biotrophic specialists that successfully manipulate their host plants and cause fascinating phenotypes in so far largely enigmatic ways. 
  • 189
  • 02 Jan 2024
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