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Topic Review
H2S in Oncological Disorders and Non-Coding RNAs Regulation
H2S is colorless, flammable, and water-soluble gas with a characteristic smell of rotten eggs; it is now widely recognized as an endogenous biological mediator. Since its discovery, H2S has been found to have vital functions in various physiological and pathological conditions. Non-coding RNAs (ncRNAs) form a relatively recent class of post-transcriptional regulators that is widely expanding. Non-coding RNAs (ncRNAs) have been reported to play a dominating role in the regulation of the endogenous machinery system of H2S in several pathological contexts. A growing list of microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are leading the way as upstream regulators for H2S biosynthesis in different mammalian cells during the development and progression of human diseases.
  • 190
  • 05 Feb 2024
Topic Review
Onco-Breastomics: An Eco-Evo-Devo Holistic Approach
Many mechanisms of cancer progression have been explained by principles of ecology, developmental biology, and evolutionary paradigms. Many authors have discussed ecological, developmental, and evolutionary strategies for more successful anti-cancer therapies, or for understanding the ecological, developmental, and evolutionary bases of breast cancer (BC) exploitable vulnerabilities. Researchers use the integrated framework of three well known ecological theories: the Bronfenbrenner’s theory of human development, the Vannote’s River Continuum Concept (RCC), and the Ecological Evolutionary Developmental Biology (Eco-Evo-Devo) theory, to explain and understand several eco-evo-devo-based principles that govern BC progression.
  • 168
  • 05 Feb 2024
Topic Review
Microbial Therapy and Breast Cancer Management
Microorganisms play an indirect role in affecting the emergence, natural course, and/or severity of various cancers. The presence of a unique microbiome in breast tissue, previously unacknowledged, has gained recognition through research. Microbiome dissimilarities have been observed between healthy and cancerous breast tissue, implying that cancer may disturb the natural balance of the microbiome in this area. Interestingly, breast tumor tissue showed a decrease in total bacterial DNA, and an inverse relationship was observed between the bacterial DNA load and advanced cancer stages.
  • 134
  • 05 Feb 2024
Topic Review
Rare Earth Elements (REE)
The rare earth elements (REE) comprise a group of 16 chemically very similar elements that occur widespread in rocks, soils, and water bodies, share similar ionic radii to the essential element Ca2+, and consequently also occur in biota. Given that REE form mainly trivalent cations, they also share similarities to Al3+. Compared to their chemical cognate Ca, they have a higher reactivity. Thus, their accumulation in soils may constitute a severe environmental threat. Over the last decades, the increasing use of REE in modern technology and fertilizers raised concerns about the pollution of soils and water bodies, which led to a rapidly increasing number of publications dealing with REE toxicity to plants, animals and humans, the fate of REE in soil–plant systems, REE cycling in ecosystems and impacts of REE pollution on food security.
  • 303
  • 05 Feb 2024
Topic Review
Food Applications of W1/O/W2 and O1/W/O2 DEs
Double emulsions (DEs) present promising applications as alternatives to conventional emulsions in the pharmaceutical, cosmetic, and food industries. Generally, double emulsions are classified into two main categories, water-in-oil-in-water emulsions denoted by W1/O/W2 and oil-in-water-in-oil emulsions denoted by O1/W/O2, to distinguish between two aqueous and oil phases with different compositions
  • 233
  • 05 Feb 2024
Topic Review
Wood Vinegar as Antimicrobial Agent in Animal Husbandry
Wood vinegar (WV), also known as pyroligneous acid, as an alternative antimicrobial with good potential to replace conventional products. Many studies have demonstrated that WV is a promising product. WV is a nontoxic additive widely employed in the food industry to impart a smoked flavor to foods. Studies have shown that, depending on the WV concentration, good results can be achieved using it as an antimicrobial against pathogenic bacteria and fungi and a valuable growth promoter for poultry and pigs.
  • 320
  • 05 Feb 2024
Topic Review
Insights into AMR Mechanisms from Laboratory Evolution
Laboratory evolution studies provide invaluable insights into the dynamic landscape of resistance, revealing intricate details about the evolutionary trajectories, population dynamics, and metabolic adaptations shaping bacterial responses to drug exposure. The complex interplay of cross-resistance and collateral sensitivity in the evolution of antimicrobial resistance (AMR) has been intensively analyzed using E. coli as a model bacterium.
  • 296
  • 05 Feb 2024
Topic Review
Abyssinian genet
The Abyssinian genet (Genetta abyssinica) is a carnivorous mammal belonging to the family Viverridae. Endemic to the highlands of Ethiopia, it is characterized by its sleek, spotted coat and long tail. This nocturnal creature plays a vital role in local ecosystems as an efficient hunter of small vertebrates and insects.
  • 221
  • 04 Feb 2024
Topic Review
Side-striped Jackal
The Side-striped Jackal (Canis adustus) is a medium-sized carnivore native to sub-Saharan Africa. Identified by the distinct white stripe running along its flanks, this adaptable canid inhabits a variety of habitats, demonstrating omnivorous feeding habits and a complex social structure within its family groups.
  • 250
  • 04 Feb 2024
Topic Review
White-tailed Mongoose
The White-tailed Mongoose (Ichneumia albicauda) is a captivating carnivorous mammal native to the African continent, distinguished by its striking white-tipped tail and sleek, slender physique. Inhabiting a variety of habitats, from woodlands to grasslands, this elusive mongoose species plays a vital role in the ecosystems it calls home.
  • 291
  • 04 Feb 2024
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