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Topic Review
Streptobacillus Moniliformis
Streptobacillus moniliformis is a non-motile, Gram-negative rod-shaped bacterium that is a member of the family Leptotrichiaceae. The genome of S. moniliformis is one of two completed sequences of the order Fusobacteriales. Its name comes from the Greek word streptos for "curved" or "twisted", and the Latin words bacillus meaning "small rod" and moniliformis for "necklace". S. moniliformis is microaerophilic, requiring less oxygen than is present in the atmosphere for its growth.
  • 639
  • 03 Nov 2022
Topic Review
Streptavidin
Streptavidin /ˌstrɛpˈtævɪdɪn/ is a 52.8 kDa protein purified from the bacterium Streptomyces avidinii. Streptavidin homo-tetramers have an extraordinarily high affinity for biotin (also known as vitamin B7 or vitamin H). With a dissociation constant (Kd) on the order of ≈10−14 mol/L, the binding of biotin to streptavidin is one of the strongest non-covalent interactions known in nature. Streptavidin is used extensively in molecular biology and bionanotechnology due to the streptavidin-biotin complex's resistance to organic solvents, denaturants (e.g. guanidinium chloride), detergents (e.g. SDS, Triton), proteolytic enzymes, and extremes of temperature and pH.
  • 1.5K
  • 25 Oct 2022
Topic Review
Street Dog Sterilisation Programmes
Humane Society International (HSI) facilitates dog sterilisation programmes internationally, which includes population surveys of street dogs to gain basic demographic information and to set a baseline for future monitoring operations. HSI has developed a web and mobile application suite called ‘HSIApps’ with custom tailored workflows to improve the efficiency (lower programmatic cost) and improve the welfare of dogs in care throughout the sterilisation process.
  • 709
  • 30 Aug 2022
Topic Review
STRC Gene
Stereocilin: The STRC gene provides instructions for making a protein called stereocilin. 
  • 519
  • 24 Dec 2020
Topic Review
Strawberry Fungal Leaf Scorch Disease Identification
Plant health is the basis of agricultural development. Plant diseases are a major factor for crop losses in agriculture. Plant diseases are difficult to diagnose correctly, and the manual disease diagnosis process is time consuming. For this reason, it is highly desirable to automatically identify the diseases in strawberry plants to prevent loss of crop quality. Deep learning (DL) has recently gained popularity in image classification and identification due to its high accuracy and fast learning. In this research, deep learning models were used to identify the leaf scorch disease in strawberry plants. Four convolutional neural networks (SqueezeNet, EfficientNet-B3, VGG-16 and AlexNet) CNN models were trained and tested for the classification of healthy and leaf scorch disease infected plants. The performance accuracy of EfficientNet-B3 and VGG-16 was higher for the initial and severe stage of leaf scorch disease identification as compared to AlexNet and SqueezeNet. It was also observed that the severe disease (leaf scorch) stage was correctly classified more often than the initial stage of the disease. All the trained CNN models were integrated with a machine vision system for real-time image acquisition under two different lighting situations (natural and controlled) and identification of leaf scorch disease in strawberry plants. The field experiment results with controlled lightening arrangements, showed that the model EfficientNet-B3 achieved the highest classification accuracy, with 0.80 and 0.86 for initial and severe disease stages, respectively, in real-time. AlexNet achieved slightly lower validation accuracy (0.72, 0.79) in comparison with VGGNet and EfficientNet-B3. Experimental results stated that trained CNN models could be used in conjunction with variable rate agrochemical spraying systems, which will help farmers to reduce agrochemical use, crop input costs and environmental contamination.
  • 451
  • 18 Jan 2022
Topic Review
Strawberry Biostimulation
Plant biostimulation consists of using or applying physical, chemical, or biological stimuli that trigger a response—called induction or elicitation—with a positive effect on crop growth, development, and quality. Biostimulation provides tolerance to biotic and abiotic stress, and more absorption and accumulation of nutrients, favoring the metabolism of the plants. The strawberry is a highly appreciated fruit for its high organoleptic and nutraceutical qualities since it is rich in phenolic compounds, vitamins, and minerals, in addition to being a product with high commercial value.
  • 512
  • 13 Jan 2023
Topic Review
Strategies to Target Myofibroblasts for Scarless Skin Healing
Myofibroblasts have drawn much attention among scientific research communities from multiple disciplines and specialisations. As further research uncovers the characterisations of myofibroblast formation, function, and regulation, the realisation of novel interventional routes for myofibroblasts within pathologies has emerged. The research community is approaching the means to finally target these cells, to prevent fibrosis, accelerate scarless wound healing, and attenuate associated disease-processes in clinical settings.
  • 293
  • 11 Aug 2023
Topic Review
Strategies to Potentiate the Therapeutic Properties of MSCs
Beneficial properties of mesenchymal stromal cells (MSCs) have prompted their use in preclinical and clinical research. Accumulating evidence has been provided for the therapeutic effects of MSCs in several pathologies, including neurodegenerative diseases, myocardial infarction, skin problems, liver disorders and cancer, among others. Although MSCs are found in multiple tissues, the number of MSCs is low, making in vitro expansion a required step before MSC application. However, culture-expanded MSCs exhibit notable differences in terms of cell morphology, physiology and function, which decisively contribute to MSC heterogeneity. The changes induced in MSCs during in vitro expansion may account for the variability in the results obtained in different MSC-based therapy studies, including those using MSCs as living drug delivery systems. 
  • 297
  • 24 Jun 2022
Topic Review
Strategies to Mitigate Against Pathogenic Drug Resistant Fungi
Antifungal resistance, antifungal drug tolerance, and biofilm formation directly contribute to rising cases of fungal morbidity and mortality. As with all of the infectious diseases, prevention is the optimal way to mitigate disease outbreak and transmission. The application of effective disinfection and sterilization regimes, particularly in hospital settings, is vitally important, where a focus on fungal biofilm formation on indwelling medical devices is important. Preventing the growth of mycotoxin-producing fungi on foods through the performance of appropriate end-to-end processes is advisable, as mycotoxins are recalcitrant and challenging to eliminate once they have been formed. Adopting the OneHealth approach will support and enable solutions to address this complex societal challenge.
  • 521
  • 31 Jan 2023
Topic Review
Strategies to Manage an Outbreak for Avian Influenza
Avian influenza (AI) is a contagious disease among the poultry population with high avian mortality, which generates significant economic losses and elevated costs for disease control and outbreak eradication. AI is caused by an RNA virus part of the Orthomyxoviridae family; however, only Influenzavirus A is capable of infecting birds. AI pathogenicity is based on the lethality, signs, and molecular characteristics of the virus. Low pathogenic avian influenza (LPAI) virus has a low mortality rate and ability to infect, whereas the highly pathogenic avian influenza (HPAI) virus can cross respiratory and intestinal barriers, diffuse to the blood, damage all tissues of the bird, and has a high mortality rate.
  • 262
  • 26 Apr 2023
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