Topic Review
Gastro-
Gastro- is a common English-language prefix derived from the ancient Greek γαστήρ gastēr ("stomach").
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  • 25 Oct 2022
Topic Review
Homocysteine and Mitochondria
Elevated concentration of homocysteine (Hcy) in the blood plasma, hyperhomocysteinemia (HHcy), has been implicated in various disorders, including cardiovascular and neurodegenerative diseases. Accumulating evidence indicates that pathophysiology of these diseases is linked with mitochondrial dysfunction. Mitochondria are essential for maintaining cellular homeostasis and function. The interaction between Hcy and mitochondria is complex and reactive oxygen species (ROS) seem to be important mediators of Hcy effects. Although oxidative damage to mitochondria is frequently demonstrated under HHcy, Hcy may have also beneficial effects on mitochondrial function and cell viability.
  • 1.3K
  • 11 Nov 2020
Topic Review
Epstein–Barr Virus Latency
Epstein–Barr virus (EBV) is one of eight known herpesviruses with the potential to infect humans. EBV latency, and more particularly the proteins expressed during this phase of the viral cycle, is heavily implicated in EBV-mediated oncogenesis.
  • 1.3K
  • 30 Nov 2022
Topic Review
Potato Affected by Heat and Drought Stress
Potato crop species are highly prone to different abiotic (high-temperature stress, drought, salinity, and mineral stress).
  • 1.3K
  • 01 Nov 2022
Topic Review
WASF3
WASF3 (WAVE3), a Wiskott–Aldrich syndrome protein family member, appears to play a major role not only in the regulation of actin cytoskeleton dynamics but also in cancer cell invasion/metastasis. Blocking the WASF3-dependent metastatic signaling network remains an attractive and promising therapeutic option for the treatment of advanced tumors. 
  • 1.3K
  • 02 Feb 2021
Topic Review
Metabolic Reprogramming
Metabolic reprogramming is now recognized as a hallmark of cancer cells and supports cancer growth. Elucidating the underlying mechanisms of metabolic reprogramming in cancer cells may help identifying cancer targets and treatment strategies.
  • 1.3K
  • 20 Jan 2021
Topic Review
Biogas as Energy in Rural Sector and Significance
In rural areas, where access to conventional energy sources is limited, alternative energy options such as biogas production offer tremendous potential. The sustainable utilization of biowaste resources for biogas production is a promising solution for meeting rural bioenergy requirements. Biowaste, such as agricultural residues, food waste, and animal manure, represents a significant source of organic material that can be converted into biogas through anaerobic digestion.
  • 1.3K
  • 27 Jul 2023
Topic Review
Neutrophils in Obesity
Obesity is characterized by an increase in body weight associated with an exaggerated enlargement of the adipose tissue. Accumulation of fat in adipose tissue causes stress and malfunction of adipocytes, which then initiate inflammation. Next, adipose tissue is infiltrated by cells of the innate immune system. It has become evident that neutrophils, the most abundant leukocytes in blood, are the first immune cells infiltrating the adipose tissue. Neutrophils then get activated and release inflammatory factors that recruit macrophages and other immune cells. These immune cells, in turn, perpetuate the inflammation state by producing cytokines and chemokines that can reach other parts of the body, creating a systemic inflammatory condition.
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  • 14 Jul 2022
Topic Review Video
Bee Nutritional Demands
For all bee species, the pollen quality determines the overall quality of the larval food, influences the development of individuals and shapes their populations. However, not all plants produce pollen that fully satisfies the nutritional requirements of bees. Lack of understanding of the nutritional requirements of wild bees may lead to unintended negative effects of conservation efforts. Ecological stoichiometry provides an approach to better understand the nutritional constraints on growing and developing organisms and their colonies and populations. It makes reference to elements that, if scarce in the environment, prevent the construction of biologically important organic molecules. The least understood aspect of the nutritional requirements of bees concerns stoichiometric balancing and the need for adequate ratios of nutritional elements in consumed food. This text provides theoretical foundation for the project aiming at determining the likely limitations imposed on wild bees by the lack of nutritionally balanced pollen. The following hypotheses may be tested: 1. Pollen stoichiometry vary among plant species and populations but will differ more widely among species than within different populations of the same species.2. The stoichiometry of bees will vary substantially among bee species and between sexes within a species, which suggests the existence of different nutritional demands. Therefore, it is expected that the stoichiometric mismatches experienced by bees will vary in a species-specific and sex-specific manner.3. For a given bee species, specific pollen species allow the overcoming of stoichiometric mismatches and will balance the diet. Accordingly, it is expected expect that flora diversity and, thus, pollen diversity matches the stoichiometric niches of bees. I predict that the occurrence of specific key host plant species that produce stoichiometrically desirable pollen allows bees to stoichiometrically balance their diets. The project may ask if and how floral diversity, particularly the accessibility of nutritionally desirable key species, may influence bee populations. The obtained data will allow the parameterization of a conceptual model of nutritional limitations (to be developed in the future), which will enable to predict how floral community influences wild bee populations via supply and demand of nutrients.
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  • 05 Nov 2020
Topic Review
Tea and Its Active Constituents in Cosmetics
Tea plant itself and its extracts together with their centuries-old tradition of use play an important role on the cosmetics market. In general, cosmetics products containing tea extracts rich in polyphenols have a positive effect on the skin appearance and ameliorate skin damage, erythema and lipid peroxidation following UV exposure.
  • 1.3K
  • 29 Mar 2022
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