Topic Review
Transformation of Natural Philosophy
Is there any reason, to believe a modern natural philosophy makes sense? The history of natural philosophy is marked by the search for principles that determine all beings independently whether they are abiotic matter or living organisms. Empirical data on the key features of life contradict even the possibility to find such principles because life in contrast to abiotic matter offers some main characteristics that are completely absent on abiotic planets. This means, if a modern natural philosophy should have any benefit it must be divided into a natural philosophy of physics or cosmology and a natural philosophy of life. If it is possible to give an updated definition of life, empirically based, non-reductive, non-mechanistic and without metaphysical assumptions, this would be an appropriate basis for a global consensus how future of humans may be generated in symbiosis with global biosphere. If we think on billions invested in health and drug research a new natural philosophy of life could orientate future of research on health and new drugs and avoid misinvestments.
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  • 09 Nov 2020
Topic Review
Michelia × alba (M. alba)
Michelia × alba (M. alba) is a flowering tree best known for its essential oil, which has long been used as a fragrance ingredient for perfume and cosmetics. 
  • 2.2K
  • 10 Jun 2022
Topic Review
Short-Term Memory
Short-term memory (or "primary" or "active memory") is the capacity for holding, but not manipulating, a small amount of information in mind in an active, readily available state for a short period of time. For example, short-term memory can be used to remember a phone number that has just been recited. The duration of short-term memory (when rehearsal or active maintenance is prevented) is believed to be in the order of seconds. A commonly cited capacity of items to remember is The Magical Number Seven, Plus or Minus Two (also called Miller's Law, despite Miller calling the figure "little more than a joke" (Miller, 1989, page 401)). Cowan (2001) suggests that a more realistic figure is 4±1 items. In contrast, long-term memory holds information indefinitely. Short-term memory should be distinguished from working memory, which refers to structures and processes used for temporarily storing and manipulating information (see details below).
  • 2.2K
  • 12 Oct 2022
Topic Review
Medicinal Value of Dandelion
The genus Taraxacum is part of the Asteraceae family of the Cichorioideae subfamily, Lactuceae tribe. This plant's geographical distribution is usually around the warm areas of the Northern Hemisphere and its users have been cherishing it for its curative properties since ancient times. Reports show that traditional medicine practitioners used Taraxacum officinale L. for treating dyspepsia, spleen, liver disorders, hepatitis, and anorexia. Aqueous extracts of dandelion were also used traditionally through Asia, Europe, and North America for treating different types of cancer like leukemia and breast cancer, even if their working mechanisms were unknown. The main reported components of dandelions consist of phenolic acids (chicoric, caffeic, and chlorogenic acids), terpenes (taraxacoside, ainslioside, taraxinic acid), and storage carbohydrates (inulin), which are thought to be accountable for the plant’s health-related properties. This entry is based on a literature review and highlights the beneficial and therapeutic action of dandelion extracts and their confirmed or hypothesized mechanism of action in diabetes, hepatic disorders, and cardiovascular disease, as indicated by the results of in vivo an in vitro studies, on cell lines, human and animal models.
  • 2.2K
  • 10 May 2021
Topic Review
Vitamin D Metabolism Gene Polymorphisms
Vitamin D is a potent immunonutrient that through its main metabolite calcitriol, regulates the immunomodulation of macrophages, dendritic cells, T and B lymphocytes, which express the vitamin D receptor (VDR), and they produce and respond to calcitriol. Genetic association studies have shown that up to 65% of vitamin D serum variance may be explained due to genetic background. 
  • 2.2K
  • 01 Jan 2022
Topic Review
Light, Water, and Melatonin Relationship with Hydrogen Bonds
The synergistic relationship between melatonin, water, and light may have originated billions of years ago when primitive unicellular organisms depended on this effective and precise synergy to modulate phase separation to control protein aggregation and associated biological effects. The efficacy of this synergy also provides a credible explanation for the immensely successful and rapid distribution of melatonin via horizontal gene transfer. The discovery of the serotonin N-acetyltransferase (SNAT) gene responsible for the synthesis of essential melatonin substrate N-acetylserotonin (NAS) in archaea firmly establishes the quintessential role played by melatonin in early primitive organisms that use phase separation as the fundamental driver for relevant biochemical and biophysical processes to support metabolism, replication, and survival.
  • 2.2K
  • 27 Mar 2023
Topic Review
Forensic Facial Comparison
Forensic facial comparison is a human observer-based technique employed in forensic facial identification. Facial identification falls under the broader discipline of facial imaging, and involves the use of visual facial information to assist in person identification. Through the analysis of photographic or video evidence (e.g., CCTV), forensic facial identification is routinely utilized to associate persons of interest to criminal activity in a judicial context. The recommended approach to forensic facial comparison is facial examination by morphological analysis, whereby a facial feature list is used to analyze, compare, and evaluate visible facial features between a target image and a potential matching image. This process is then validated by a second analyst. Forensic facial comparison, and its broader discipline of facial identification, should not be confused with automated facial recognition technology or the innate psychological process of facial recognition.
  • 2.2K
  • 13 Dec 2021
Topic Review
Medicinal Value of Chicory
Cichorium intybus L., commonly named chicory, is a perennial herbal plant of the dandelion family Asteraceae, mainly seen with bright blue flowers, and seldom pink or white. Generally distributed in Asia and Europe, all the plants’ parts were traditionally used in medicinal preparations due to their considerable contents of antioxidant phytochemicals thought to have a beneficial impact in preventing and treating various illnesses such as fever, diarrhea, jaundice, and gallstones. Different chicory types are grown for their salad leaves, chicons, or roots, and regularly used for inulin extraction, for preparing coffee substitutes, or for feeding livestock. This entry is based on a literature review and highlights the beneficial and therapeutic action of chicory extracts and their confirmed or hypothesized mechanism of action in diabetes, hepatic disorders, and cardiovascular disease, as indicated by the results of in vivo and in vitro studies, on cell lines, human and animal models.
  • 2.2K
  • 10 May 2021
Topic Review
Phospholipase A1
Phospholipase A1 (PLA1) is an enzyme that cleaves an ester bond at the sn-1 position of glycerophospholipids, producing a free fatty acid and a lysophospholipid.
  • 2.2K
  • 27 Apr 2022
Topic Review
The Impact of Climate Change on Egyptian Livestock
Egypt is one of the hottest countries in the world, and extreme climate events are becoming more frequent, which is consistent with the warming of the planet. The impact of this warming on ecosystems is severe, including on livestock production systems. Under Egyptian conditions, livestock already suffer heat stress periods in summer. The predicted increases in temperature as result of climate change will affect livestock production by reducing growth and milk production because of appetite suppression and conception rate reductions and will increase animal welfare concerns. In severe cases, these effects can result in death.
  • 2.2K
  • 05 Aug 2022
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