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Topic Review
Biography
Topic Review
Histone Loss in Aging and Senescence
Aging is a complex and multifactorial process characterized by a combination of aging hallmarks that contribute to declines at the molecular, cellular, and systemic levels in an organism. The dysregulation of the cellular epigenome during aging and senescence is a complex phenomenon that manifests through various elements, including global histone levels, histone positioning on the DNA sequence, post-translational modifications (PTMs) of histones, histone variants, DNA methylation, and noncoding RNAs.
179
27 Feb 2024
Topic Review
Resurrection Plants as Source of Natural Bioactive Compounds
Resurrection plant species are a group of higher plants whose vegetative tissues are able to withstand long periods of almost full desiccation and recover quickly upon rewatering. Apart from being a model system for studying desiccation tolerance, resurrection plant species appear to be a valuable source of metabolites, with various areas of application. A significant number of papers have been published with respect to the extraction and application of bioactive compounds from higher resurrection plant species in various test systems. Promising results have been obtained with respect to antioxidative and antiaging effects in various test systems, particularly regarding valuable anticancer effects in human cell lines.
113
27 Feb 2024
Topic Review
Pharmaceuticals with Obesogen Action Impact Male Fertility
Obesogens have been identified as a significant factor associated with increasing obesity rates, particularly in developed countries. Substances with obesogenic traits are prevalent in consumer products, including certain pharmaceuticals. Specific classes of pharmaceuticals have been recognized for their ability to induce weight gain, often accompanied by hormonal alterations that can adversely impact male fertility.
96
27 Feb 2024
Topic Review
Toxic Effects of Pyrrolizidine Alkaloids
Pyrrolizidine alkaloids (PAs) are naturally occurring secondary metabolites of plants. More than 660 types of PAs have been identified from an estimated 6000 plants, and approximately 120 of these PAs are hepatotoxic. As a result of PAs being found in spices, herbal teas, honey, and milk, PAs are considered contaminants in foods, posing a potential risk to human health.
208
27 Feb 2024
Topic Review
Breeding Approaches for Orchid Cultivation and Conservation
Orchid cultivation is gaining momentum attributed to the development of new orchid varieties with unique features of colors and appearance. To bridge this demand and supply gap, both traditional and molecular breeding approaches are employed with consistent efforts.
321
27 Feb 2024
Topic Review
Sarcocystis
Infecting Old World and South American camelids
Sarcocystis spp. are coccidian protozoans belonging to the Apicomplexa phylum. As with other members of this phylum, they are obligate intracellular parasites with complex cellular machinery for the invasion of host cells. Sarcocystis spp. display dixenous life cycles, involving a predator and a prey as definitive and intermediate hosts, respectively. Specifically, these parasites develop sarcocysts in the tissues of their intermediate hosts, ranging in size from microscopic to visible to the naked eye, depending on the species. When definitive hosts consume sarcocysts, infective forms are produced in the digestive system and discharged into the environment via feces.
139
27 Feb 2024
Topic Review
Plant Microbial Fuel Cells
PubMed (NCBI) has pointed to an exponential growth of publications on the subject of a “biofuel cell” in the first decade of our century, and this interest persisted throughout the following years. It should be noted that biofuel elements based on microorganisms (microbial fuel cells, MFCs) are a promising technology to produce bioelectricity since they simultaneously solve the problems of contamination with anthropogenic organic waste, which can be used by microorganisms as a source of carbon and energy.
321
27 Feb 2024
Topic Review
Essential Oils in Meat Preservation
Consumers are looking for safer and more natural food options that are produced through natural methods without using synthetic preservatives. They also desire extended shelf life for their food products. Several medicinal and aromatic plants species combine food, spice, aromatic, and medicinal recognized attributes. The essential oils from these plants contain a unique mixture of compounds specific to each plant, showing notable antioxidant and antimicrobial properties.
131
27 Feb 2024
Topic Review
Development and Growth of Intramuscular Fat in Cattle
Besides protein, beef contains a significant amount of fat. Intramuscular fat (IMF), also referred to as marbling fat, is the white fat deposited within skeletal muscle tissue. The content of intramuscular fat in the skeletal muscle, particularly the longissimus dorsi muscle, of cattle is a critical determinant of beef quality and value. Physiologically, IMF is believed to have similar functions to other fat depots in cattle, serving as an energy reserve and providing fuel during times of increased metabolic demand or inadequate nutrient supply. As food, IMF substantially enhances the texture and flavor of the meat and the overall satisfaction of consumers.
166
27 Feb 2024
Topic Review
Cell Envelope Synthesis Enzymes
Life-threatening systemic fungal infections occur in immunocompromised patients at an alarming rate. Current antifungal therapies face challenges like drug resistance and patient toxicity, emphasizing the need for new treatments. Membrane-bound enzymes account for a large proportion of antifungal targets, especially ones that contribute to cell wall and cell membrane biosynthesis. Moreover, structural biology has led to a better understanding of the mechanisms by which these enzymes synthesize their products, as well as the mechanism of action for some antifungals.
178
27 Feb 2024
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